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mAbs Volume 13, 2021 - Issue 1
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Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope

Wing Ki Wonga Department of Statistics, University of Oxford, Oxford, UKORCID Iconhttps://orcid.org/0000-0003-4029-6902View further author information
ORCID Icon,
Sarah A. Robinsona Department of Statistics, University of Oxford, Oxford, UKORCID Iconhttps://orcid.org/0000-0003-2500-0173View further author information
ORCID Icon,
Alexander Bujotzekb Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, GermanyView further author information
,
Guy Georgesb Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, GermanyORCID Iconhttps://orcid.org/0000-0001-5737-006XView further author information
ORCID Icon,
Alan P. Lewisc Data and Computational Sciences, GlaxoSmithKline Research and Development, Stevenage, UKView further author information
,
Jiye Shid UCB Pharma, Slough, UKORCID Iconhttps://orcid.org/0000-0002-9628-8680View further author information
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James Snowdend UCB Pharma, Slough, UKView further author information
,
Bruck Taddesee Discovery Sciences, BioPharmaceuticals, R&D, AstraZeneca, Cambridge, UKView further author information
&
Charlotte M. Deanea Department of Statistics, University of Oxford, Oxford, UKCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1388-2252View further author information
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Article: 1873478 | Received 05 Oct 2020, Accepted 04 Jan 2021, Published online: 15 Jan 2021

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Rahul Khetan, Robin Curtis, Charlotte M. Deane, Johannes Thorling Hadsund, Uddipan Kar, Konrad Krawczyk, Daisuke Kuroda, Sarah A. Robinson, Pietro Sormanni, Kouhei Tsumoto, Jim Warwicker & Andrew C.R. Martin. (2022) Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics. mAbs 14:1.
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Rahmad Akbar, Habib Bashour, Puneet Rawat, Philippe A. Robert, Eva Smorodina, Tudor-Stefan Cotet, Karine Flem-Karlsen, Robert Frank, Brij Bhushan Mehta, Mai Ha Vu, Talip Zengin, Jose Gutierrez-Marcos, Fridtjof Lund-Johansen, Jan Terje Andersen & Victor Greiff. (2022) Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies. mAbs 14:1.
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Matthew I. J. Raybould, Anthony R. Rees & Charlotte M. Deane. (2021) Current strategies for detecting functional convergence across B-cell receptor repertoires. mAbs 13:1.
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Articles from other publishers (10)

Jonathan Hurtado, Claudia Flynn, Jeong Hyun Lee, Eugenia C. Salcedo, Christopher A. Cottrell, Patrick D. Skog, Dennis R. Burton, David Nemazee, William R. Schief, Elise Landais, Devin Sok & Bryan Briney. (2023) Efficient isolation of rare B cells using next-generation antigen barcoding. Frontiers in Cellular and Infection Microbiology 12.
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Ahmadreza Ghanbarpour, Min Jiang, Denisa Foster & Qing Chai. (2023) Structure-free antibody paratope similarity prediction for in silico epitope binning via protein language models. iScience 26:2, pages 106036.
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Jennifer Cable, Erica Ollmann Saphire, Adrian C. Hayday, Timothy D. Wiltshire, Jarrod J. Mousa, David P. Humphreys, Esther C. W. Breij, Pierre Bruhns, Matteo Broketa, Genta Furuya, Blake M. Hauser, Matthieu Mahévas, Andrea Carfi, Tineke Cantaert, Peter D. Kwong, Prabhanshu Tripathi, Jonathan H. Davis, Neil Brewis, Bruce A. Keyt, Felix L. Fennemann, Vincent Dussupt, Arvind Sivasubramanian, Philip M. Kim, Reda Rawi, Eve Richardson, Daniel Leventhal, Rachael M. Wolters, Cecile A. W. Geuijen, Matthew A. Sleeman, Niccolo Pengo & Francesca Rose Donnellan. (2022) Antibodies as drugs—a Keystone Symposia report. Annals of the New York Academy of Sciences 1519:1, pages 153-166.
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David B. Jaffe, Payam Shahi, Bruce A. Adams, Ashley M. Chrisman, Peter M. Finnegan, Nandhini Raman, Ariel E. Royall, FuNien Tsai, Thomas Vollbrecht, Daniel S. Reyes, N. Lance Hepler & Wyatt J. McDonnell. (2022) Functional antibodies exhibit light chain coherence. Nature 611:7935, pages 352-357.
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Young-Han Son, Dong-Hee Shin, Ji-Wung Han, Seong-Hyeon Won & Tae-Eui Kam. (2022) GNN-based Antibody Structure Prediction using Quaternion and Euler Angle Combined Representation. GNN-based Antibody Structure Prediction using Quaternion and Euler Angle Combined Representation.
Zichang Xu, Hendra S. Ismanto, Hao Zhou, Dianita S. Saputri, Fuminori Sugihara & Daron M. Standley. (2022) Advances in antibody discovery from human BCR repertoires. Frontiers in Bioinformatics 2.
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Hendra S. Ismanto, Zichang Xu, Dianita S. Saputri, Jan Wilamowski, Songling Li, Dendi K. Nugraha, Yasuhiko Horiguchi, Masato Okada, Hisashi Arase & Daron M Standley. (2022) Landscape of infection enhancing antibodies in COVID-19 and healthy donors. Computational and Structural Biotechnology Journal 20, pages 6033-6040.
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Jarjapu Mahita, Dong-Gun Kim, Sumin Son, Yoonjoo Choi, Hak-Sung Kim & Chris Bailey-Kellogg. (2022) Computational epitope binning reveals functional equivalence of sequence-divergent paratopes. Computational and Structural Biotechnology Journal 20, pages 2169-2180.
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Sarah A. Robinson, Matthew I. J. Raybould, Constantin Schneider, Wing Ki Wong, Claire Marks & Charlotte M. Deane. (2021) Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies. PLOS Computational Biology 17:12, pages e1009675.
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Matthew I. J. Raybould, Claire Marks, Aleksandr Kovaltsuk, Alan P. Lewis, Jiye Shi & Charlotte M. Deane. (2021) Public Baseline and shared response structures support the theory of antibody repertoire functional commonality. PLOS Computational Biology 17:3, pages e1008781.
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