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Improved therapeutic index of an acidic pH-selective antibody

Peter S. Leea Discovery Biotherapeutics, Bristol Myers Squibb, Redwood City, CA, USACorrespondence[email protected]

https://orcid.org/0000-0002-8745-4034 View further author information

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Katherine G. MacDonaldb Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USACorrespondence[email protected]
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Evan Massib Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USAView further author information

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Pamela V. Chewc Oncology Biology, Gilead Sciences, Foster City, CA, USAView further author information

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Christine Beed Discovery Biology, Frontier Medicines, South San Francisco, CA, USAView further author information

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Padma Perkinsb Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USAView further author information

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Bryant Chaue Kyverna, Synthetic Biology, Emeryville, CA, USAView further author information

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Kent Thudiumb Immuno-Oncology Research, Bristol Myers Squibb, Redwood City, CA, USAView further author information

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Jack Lohref In Vivo Pharmacology, Bristol Myers Squibb, Redwood City, CA, USAView further author information

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Pradyot Nandig Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, NJ, USAView further author information

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Ekaterina G. Deyanovag Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, NJ, USAView further author information

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Ishita Barmanh Therapeutic Discovery, 3T Biosciences, South San Francisco, CA, USAView further author information

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Olafur Gudmundssong Pharmaceutical Candidate Optimization, Bristol Myers Squibb, Lawrenceville, NJ, USAView further author information

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Gavin Dollingera Discovery Biotherapeutics, Bristol Myers Squibb, Redwood City, CA, USAView further author information

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Tim Sprouli In Vivo Pharmacology, UNITY Biotechnology, South San Francisco, CA, USAView further author information

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John J. Engelhardtj Immuno-Oncology Discovery, Abbvie, South San Francisco, CA, USAView further author information

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Pavel Stropk Biologics Discovery, Tallac Therapeutics, Burlingame, CA, USAView further author information

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Arvind Rajpall Large Molecule Drug Discovery, Genentech Research and Early Development, South San Francisco, CA, USAView further author information