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mAbs Volume 14, 2022 - Issue 1
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Review

David versus goliath: ACE2-Fc receptor traps as potential SARS-CoV-2 inhibitors

Mohamed A. Alfaleha Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, JeddahSaudi Arabia;b Vaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, JeddahSaudi ArabiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3716-0019View further author information
ORCID Icon,
Ayat Zawawib Vaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, JeddahSaudi Arabia;c Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, JeddahSaudi ArabiaView further author information
,
Sawsan S. Al-Amrib Vaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, JeddahSaudi ArabiaView further author information
&
Anwar M. Hashemb Vaccines and Immunotherapy Unit, King Fahd Medical Research Center, King Abdulaziz University, JeddahSaudi Arabia;d Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, JeddahSaudi ArabiaView further author information
Article: 2057832 | Received 10 Feb 2022, Accepted 22 Mar 2022, Published online: 05 Apr 2022

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Meghan M. Verstraete, Florian Heinkel, Janessa Li, Siran Cao, Anh Tran, Elizabeth C. Halverson, Robert Gene, Elizabeth Stangle, Begonia Silva-Moreno, Sifa Arrafi, Jegarubee Bavananthasivam, Madeline Fung, Mariam Eji-Lasisi, Stephanie Masterman, Steve Xanthoudakis, Surjit Dixit, John Babcook, Brandon Clavette, Mark Fogg & Eric Escobar-Cabrera. (2023) Multivalent IgM scaffold enhances the therapeutic potential of variant-agnostic ACE2 decoys against SARS-CoV-2. mAbs 15:1.
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Articles from other publishers (5)

Mohamed A Alfaleh, Reem M Alsulaiman, Sarah A Almahboub, Leena Nezamuldeen, Ayat Zawawi, Najwa D Aljehani, Muhammad Yasir, Rwaa H Abdulal, Rami Alkhaldi, Assala Helal, Sawsan S Alamri, Jana Malki, Rowa Y Alhabbab, Turki S Abujamel, Nabil A Alhakamy, Aisha Alnami, Abdullah Algaissi, Mazen Hassanain & Anwar M Hashem. (2024) ACE2-Fc and DPP4-Fc decoy receptors against SARS-CoV-2 and MERS-CoV variants: a quick therapeutic option for current and future coronaviruses outbreaks. Antibody Therapeutics 7:1, pages 53-66.
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Rohan Ameratunga, Emily Mears, Euphemia Leung, Russell Snell, See-Tarn Woon, William Kelton, Natalie Medlicott, Anthony Jordan, William Abbott, Richard Steele, William Rolleston, Hilary Longhurst & Klaus Lehnert. (2023) Soluble wild-type ACE2 molecules inhibit newer SARS-CoV-2 variants and are a potential antiviral strategy to mitigate disease severity in COVID-19. Clinical and Experimental Immunology 214:3, pages 289-295.
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Sopisa Benjakul, Aina Karen Anthi, Anette Kolderup, Marina Vaysburd, Heidrun Elisabeth Lode, Donna Mallery, Even Fossum, Elisabeth Lea Vikse, Anna Albecka, Aleksandr Ianevski, Denis Kainov, Karine Flem Karlsen, Siri Aastedatter Sakya, Mari Nyquist-Andersen, Torleif Tollefsrud Gjølberg, Morten C Moe, Magnar Bjørås, Inger Sandlie, Leo C James & Jan Terje Andersen. (2023) A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery. PNAS Nexus 2:12.
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А. S. Zmitrukevich & A. E. Mamedova. (2023) Arterial hypertension in COVID-19. Clinical Medicine (Russian Journal) 101:1, pages 26-31.
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Corbin England, Jonathan TrejoMartinez, Paula PerezSanchez, Uddhab Karki & Jianfeng Xu. (2023) Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19. Life 13:3, pages 617.
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