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Andrew B. Waight, David Prihoda, Rojan Shrestha, Kevin Metcalf, Marc Bailly, Marco Ancona, Talal Widatalla, Zachary Rollins, Alan C Cheng, Danny A. Bitton & Laurence Fayadat-Dilman. (2023) A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties. mAbs 15:1.
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Tushar Jain, Todd Boland & Maximiliano Vásquez. (2023) Identifying developability risks for clinical progression of antibodies using high-throughput in vitro and in silico approaches. mAbs 15:1.
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Joshuaine Grant, Fei Hua, Joshua F. Apgar, John M. Burke & Diana H. Marcantonio. (2023) Mechanistic PK/PD modeling to address early-stage biotherapeutic dosing feasibility questions. mAbs 15:1.
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Marjorie A. Shapiro. (2024) Regulatory considerations in the design, development and quality of monoclonal antibodies and related products for the diagnosis and treatment of cancer. Frontiers in Oncology 14.
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Paul Arras, Han Byul Yoo, Lukas Pekar, Thomas Clarke, Lukas Friedrich, Christian Schröter, Jennifer Schanz, Jason Tonillo, Vanessa Siegmund, Achim Doerner, Simon Krah, Enrico Guarnera, Stefan Zielonka & Andreas Evers. (2023) AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study. Frontiers in Molecular Biosciences 10.
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Emily K. Makowski, Tiexin Wang, Jennifer M. Zupancic, Jie Huang, Lina Wu, John S. Schardt, Anne S. De Groot, Stephanie L. Elkins, William D. Martin & Peter M. Tessier. (2023) Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning. Nature Biomedical Engineering 8:1, pages 45-56.
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Evi B. Struble, Jonathan M. O. Rawson, Tzanko Stantchev, Dorothy Scott & Marjorie A. Shapiro. (2023) Uses and Challenges of Antiviral Polyclonal and Monoclonal Antibody Therapies. Pharmaceutics 15:5, pages 1538.
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Shufang Liu & Dhaval K. Shah. (2023) Physiologically Based Pharmacokinetic Modeling to Characterize the Effect of Molecular Charge on Whole-Body Disposition of Monoclonal Antibodies. The AAPS Journal 25:3.
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Andreas Evers, Shipra Malhotra, Wolf-Guido Bolick, Ahmad Najafian, Maria Borisovska, Shira Warszawski, Yves Fomekong Nanfack, Daniel Kuhn, Friedrich Rippmann, Alejandro Crespo & Vanita Sood. 2023. Genotype Phenotype Coupling. Genotype Phenotype Coupling
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Ranjani Gopal, Emmett Fitzpatrick, Niharika Pentakota, Akila Jayaraman, Kannan Tharakaraman & Ishan Capila. (2022) Optimizing Antibody Affinity and Developability Using a Framework–CDR Shuffling Approach—Application to an Anti-SARS-CoV-2 Antibody. Viruses 14:12, pages 2694.
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