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mAbs Volume 14, 2022 - Issue 1
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Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms

Elizabeth Sara Hechta Microchemistry, Proteomics, and Lipidomics, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Shrenik Mehtab Pharmaceutical Development, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Aaron T. Weckslerc Protein Analytical Chemistry, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Ben Aguilard IonDX, IncMonterey, CA, USAView further author information
,
Nathaniel Swansonb Pharmaceutical Development, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Wilson Phunga Microchemistry, Proteomics, and Lipidomics, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Ananya Dubey Kelsoed IonDX, IncMonterey, CA, USAView further author information
,
W. Henry Bennerd IonDX, IncMonterey, CA, USAView further author information
,
Devin Tesarb Pharmaceutical Development, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Robert F. Kelleyb Pharmaceutical Development, Genentech, IncSouth San Francisco, CA, USAView further author information
,
Wendy Sandovala Microchemistry, Proteomics, and Lipidomics, Genentech, IncSouth San Francisco, CA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4672-0762View further author information
ORCID Icon &
Alavattam Sreedharab Pharmaceutical Development, Genentech, IncSouth San Francisco, CA, USACorrespondence[email protected]
View further author information
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Article: 2135183 | Received 12 Jun 2022, Accepted 07 Oct 2022, Published online: 25 Oct 2022

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Jia Guo, Regina Kufer, Delia Li, Stefanie Wohlrab, Midori Greenwood-Goodwin & Feng Yang. (2023) Technical advancement and practical considerations of LC-MS/MS-based methods for host cell protein identification and quantitation to support process development. mAbs 15:1.
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Articles from other publishers (7)

Shao-Lei Geng, Xiao-Jie Zhao, Xi Zhang, Ji-Hong Zhang, Chun-Liu Mi & Tian-Yun Wang. (2024) Recombinant therapeutic proteins degradation and overcoming strategies in CHO cells. Applied Microbiology and Biotechnology 108:1.
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Melanie Maier, Stefan Schneider, Linus Weiss, Simon Fischer, Daniel Lakatos, Joey Studts & Matthias Franzreb. (2024) Tailoring polishing steps for effective removal of polysorbate‐degrading host cell proteins in antibody purification. Biotechnology and Bioengineering.
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Azadeh Eskandari, Thean Chor Leow, Mohd Basyaruddin Abdul Rahman & Siti Nurbaya Oslan. (2024) Recent insight into the advances and prospects of microbial lipases and their potential applications in industry. International Microbiology.
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Suyang Wu, Stephanie A. Ketcham, Claudia Corredor, Douglas Both, Yuxiang Zhao, James K. Drennen & Carl A. Anderson. (2024) Adaptive modeling optimized by the data fusion strategy: Real‐time dying cell percentage prediction using capacitance spectroscopy . Biotechnology Progress 40:2.
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Deseree J. Reid, Stephanie Thibert & Mowei Zhou. (2023) Dissecting the structural heterogeneity of proteins by native mass spectrometry. Protein Science 32:4.
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Sajid Ali, Sumera Afzal Khan, Muhammad Hamayun & In-Jung Lee. (2023) The Recent Advances in the Utility of Microbial Lipases: A Review. Microorganisms 11:2, pages 510.
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ES Hecht, EC Obiorah, X Liu, L Morrison, H Shion & M Lauber. (2022) Microflow size exclusion chromatography to preserve micromolar affinity complexes and achieve subunit separations for native state mass spectrometry. Journal of Chromatography A 1685, pages 463638.
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