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mAbs Volume 15, 2023 - Issue 1
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Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework

Romain OllierResearch, AC Immune SA, Lausanne, SwitzerlandCorrespondence[email protected]
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Aline FuchsResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Florence GauyeResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Katarzyna PiorkowskaResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Sébastien MenantResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Monisha RatnamResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Paolo MontanariResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Florence GuilhotResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Didier PhillipeResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Mickael AudrainResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Anne-Laure EgesipeResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Damien NévoltrisResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Tamara SeredeninaResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Andrea PfeiferResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Marie Kosco-VilboisResearch, AC Immune SA, Lausanne, SwitzerlandView further author information
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Tariq AfrozResearch, AC Immune SA, Lausanne, SwitzerlandCorrespondence[email protected]
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Article: 2232087 | Received 27 Mar 2023, Accepted 28 Jun 2023, Published online: 05 Jul 2023

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Marissa Mock, Alex W. Jacobitz, Christopher James Langmead, Athena Sudom, Daniel Yoo, Sara C. Humphreys, Mai Alday, Larysa Alekseychyk, Nicolas Angell, Vivian Bi, Hannah Catterall, Chen-Chun Chen, Hui-Ting Chou, Kip P. Conner, Kevin D. Cook, Ana R. Correia, Andrew Dykstra, Sudipa Ghimire-Rijal, Kevin Graham, Peter Grandsard, Joon Huh, John O. Hui, Mani Jain, Victoria Jann, Lei Jia, Sheree Johnstone, Neelam Khanal, Carl Kolvenbach, Linda Narhi, Rupa Padaki, Emma M. Pelegri-O’Day, Wei Qi, Vladimir Razinkov, Austin J. Rice, Richard Smith, Christopher Spahr, Jennitte Stevens, Yax Sun, Veena A. Thomas, Sarah van Driesche, Robert Vernon, Victoria Wagner, Kenneth W. Walker, Yangjie Wei, Dwight Winters, Melissa Yang & Iain D. G. Campuzano. (2023) Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies. mAbs 15:1.
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Tatyana A. Shelkovnikova & Guillaume M. Hautbergue. 2024. Motor Neurone Disease. Motor Neurone Disease 455 479 .
Mickael Audrain, Anne-Laure Egesipe, Noémie Tentillier, Laure Font, Monisha Ratnam, Lorene Mottier, Mathieu Clavel, Morgan Le Roux-Bourdieu, Alexis Fenyi, Romain Ollier, Elodie Chevalier, Florence Guilhot, Aline Fuchs, Kasia Piorkowska, Becky Carlyle, Steven E Arnold, James D Berry, Ruth Luthi-Carter, Oskar Adolfsson, Andrea Pfeifer, Marie Kosco-Vilbois, Tamara Seredenina & Tariq Afroz. (2023) Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF. Brain Communications 5:6.
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