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Original Articles

Pyrrolizidine alkaloids in honey: comparison of analytical methods

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Pages 332-347 | Received 04 May 2010, Accepted 30 Aug 2010, Published online: 15 Nov 2010

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Maria G. Campos, Ofélia Anjos, Manuel Chica, Pascual Campoy, Janka Nozkova, Norma Almaraz-Abarca, Lidia M. R. C. Barreto, João Carlos Nordi, Leticia M. Estevinho, Ananias Pascoal, Vanessa Branco Paula, Altino Chopina, Luis G. Dias, Živoslav L. j. Tešić, Mirjana D. Mosić, Aleksandar Ž. Kostić, Mirjana B. Pešić, Dušanka M. Milojković-Opsenica, Wiebke Sickel, Markus J. Ankenbrand, Gudrun Grimmer, Ingolf Steffan-Dewenter, Alexander Keller, Frank Förster, Chrysoula H. Tananaki, Vasilios Liolios, Dimitrios Kanelis, Maria-Anna Rodopoulou, Andreas Thrasyvoulou, Luísa Paulo, Christina Kast, Matteo A. Lucchetti, Gaëtan Glauser, Olena Lokutova, Ligia Bicudo de Almeida-Muradian, Teresa Szczęsna & Norman L. Carreck. (2021) Standard methods for pollen research. Journal of Apicultural Research 60:4, pages 1-109.
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Andressa Camargo Valese, Heitor Daguer, Carmen Maria Oliveira Muller, Luciano Molognoni, Cynthia Fernandes Pinto da Luz, Daniel de Barcellos Falkenberg, Luciano Valdemiro Gonzaga, Patricia Brugnerotto, Silvana Lima Gorniak, Fabiano Barreto, Roseane Fett & Ana Carolina Oliveira Costa. (2021) Quantification of pyrrolizidine alkaloids in Senecio brasiliensis, beehive pollen, and honey by LC-MS/MS. Journal of Environmental Science and Health, Part B 56:7, pages 685-694.
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Caroline T. Griffin, Simon M. Mitrovic, Martin Danaher & Ambrose Furey. (2015) Development of a fast isocratic LC-MS/MS method for the high-throughput analysis of pyrrolizidine alkaloids in Australian honey. Food Additives & Contaminants: Part A 32:2, pages 214-228.
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Monique de Nijs, Ingrid J.W. Elbers & Patrick P.J. Mulder. (2014) Inter-laboratory comparison study for pyrrolizidine alkaloids in animal feed using spiked and incurred material. Food Additives & Contaminants: Part A 31:2, pages 288-299.
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Christina Kast, Arne Dübecke, Verena Kilchenmann, Katharina Bieri, Michael Böhlen, Otmar Zoller, Gudrun Beckh & Cord Lüllmann. (2014) Analysis of Swiss honeys for pyrrolizidine alkaloids. Journal of Apicultural Research 53:1, pages 75-83.
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F.J. Orantes-Bermejo, J. Serra Bonvehí, A. Gómez-Pajuelo, M. Megías & C. Torres. (2013) Pyrrolizidine alkaloids: their occurrence in Spanish honey collected from purple viper’s bugloss (Echium spp.). Food Additives & Contaminants: Part A 30:10, pages 1799-1806.
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Marinela Cvetanoska, Marijana Pocrnić, Marina Stefova, Nives Galić & Jasmina Petreska Stanoeva. UHPLC-Q-TOF analysis of pyrrolizidine alkaloids in North-Macedonian honey. Food Additives & Contaminants: Part B 0:0, pages 1-11.
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Articles from other publishers (49)

Adrián Fuente-Ballesteros, Ondrej Brabenec, Aristeidis S. Tsagkaris, Ana M. Ares, Jana Hajslova & José Bernal. (2024) Comprehensive overview of the analytical methods for determining pyrrolizidine alkaloids and their derived oxides in foods. Journal of Food Composition and Analysis 125, pages 105758.
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Haiping Wu, Dingyan Fan & Jiangchuang Cheng. (2023) Development and Validation of an UHPLC–MS/MS Method for the Determination of 32 Pyrrolizidine Alkaloids in Chinese Wild Honey. Journal of AOAC INTERNATIONAL 106:1, pages 56-64.
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Sarah F. Al-Subaie, Abdullah M. Alowaifeer & Maged E. Mohamed. (2022) Pyrrolizidine Alkaloid Extraction and Analysis: Recent Updates. Foods 11:23, pages 3873.
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Tobias Schlappack, Matthias Rainer, Nikolaus Weinberger & Günther K. Bonn. (2022) Sulfonated halloysite nanotubes as a novel cation exchange material for solid phase extraction of toxic pyrrolizidine alkaloids. Analytical Methods 14:27, pages 2689-2697.
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Natalia Casado, Sonia Morante-Zarcero & Isabel Sierra. (2022) Application of the QuEChERS Strategy as a Useful Sample Preparation Tool for the Multiresidue Determination of Pyrrolizidine Alkaloids in Food and Feed Samples: A Critical Overview. Applied Sciences 12:9, pages 4325.
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Jürgen Müller, Denny Wiedow, Mohammad Said Chmit & Till Beuerle. (2022) Utilization of Biomasses from Landscape Conservation Growths Dominated by Common Ragwort (Jacobaea vulgaris Gaertn.) for Biomethanization. Plants 11:6, pages 813.
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Wu Wang, Ju Jin, Huifeng Xu, Yanling Shi, Mark Boersch & Yuhe Yin. (2022) Comparative analysis of the main medicinal substances and applications of Echium vulgare L. and Echium plantagineum L.: A review. Journal of Ethnopharmacology 285, pages 114894.
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Natalia Casado, Sonia Morante-Zarcero & Isabel Sierra. (2022) The concerning food safety issue of pyrrolizidine alkaloids: An overview. Trends in Food Science & Technology 120, pages 123-139.
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Sha Yan, Kai Wang, Yahya Al Naggar, Yvan Vander Heyden, Lingling Zhao, Liming Wu & Xiaofeng Xue. (2022) Natural plant toxins in honey: An ignored threat to human health. Journal of Hazardous Materials 424, pages 127682.
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Lorena Lucatello, Roberta Merlanti, Luciana De Jesus Inacio, Vittoria Bisutti, Ludovica Montanucci & Francesca Capolongo. (2021) Pyrrolizidine alkaloid concentrations in local Italian and retail honeys of different origin: A scenario of human exposure. Journal of Food Composition and Analysis 104, pages 104182.
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Andrew J. Pearson, Jeane E. F. Nicolas, Jane E. Lancaster & C. Wymond Symes. (2021) Characterization and Lifetime Dietary Risk Assessment of Eighteen Pyrrolizidine Alkaloids and Pyrrolizidine Alkaloid N-Oxides in New Zealand Honey. Toxins 13:12, pages 843.
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Ning Jia, Shaodong Zeng, Wuhai Chen, Hongbin Guo, Jianzhi Ye, Ling Lin & Chunliang Yang. (2021) Application of liquid chromatography-mass spectrometry technology in the detection of pyrrolizidine alkaloids in agricultural products. Journal of Physics: Conference Series 2021:1, pages 012102.
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Pavel Kalač & Florian Kaltner. (2021) Pyrrolizidine alkaloids of European Senecio/Jacobaea species in forage and their carry-over to milk: A review. Animal Feed Science and Technology 280, pages 115062.
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Christoph Gottschalk, Florian Kaltner, Matthias Zimmermann, Rainer Korten, Oliver Morris, Karin Schwaiger & Manfred Gareis. (2020) Spread of Jacobaea vulgaris and Occurrence of Pyrrolizidine Alkaloids in Regionally Produced Honeys from Northern Germany: Inter- and Intra-Site Variations and Risk Assessment for Special Consumer Groups. Toxins 12:7, pages 441.
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Natasha Hungerford, Steve Carter, Shalona Anuj, Benjamin Tan, Darina Hnatko, Christopher Martin, Elipsha Sharma, Mukan Yin, Thao Nguyen, Kevin Melksham & Mary Fletcher. (2019) Analysis of Pyrrolizidine Alkaloids in Queensland Honey: Using Low Temperature Chromatography to Resolve Stereoisomers and Identify Botanical Sources by UHPLC-MS/MS. Toxins 11:12, pages 726.
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Won Tae Jeong & Heung Bin Lim. (2019) Determination and Chemical Profiling of Toxic Pyrrolizidine Alkaloids in Botanical Samples with UPLC–Q-TOFMS. Chromatographia 82:11, pages 1653-1664.
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Jawameer R. Hama & Bjarne W. Strobel. (2019) Pyrrolizidine alkaloids quantified in soil and water using UPLC-MS/MS. RSC Advances 9:52, pages 30350-30357.
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Tingting Wang, Henrik Lauritz Frandsen, Natasha Roed Christiansson, Sofie Elisabeth Rosendal, Mikael Pedersen & Jørn Smedsgaard. (2019) Pyrrolizidine alkaloids in honey: Quantification with and without standards. Food Control 98, pages 227-237.
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Jens Flade, Heidrun Beschow, Monika Wensch-Dorendorf, Andreas Plescher & Wim Wätjen. (2019) Occurrence of Nine Pyrrolizidine Alkaloids in Senecio vulgaris L. Depending on Developmental Stage and Season. Plants 8:3, pages 54.
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Sebastian Schramm, Nikolai Köhler & Wilfried Rozhon. (2019) Pyrrolizidine Alkaloids: Biosynthesis, Biological Activities and Occurrence in Crop Plants. Molecules 24:3, pages 498.
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Oliver Keuth, Hans-Ulrich Humpf & Peter Fürst. 2019. Encyclopedia of Food Chemistry. Encyclopedia of Food Chemistry 348 355 .
Rute Moreira, David Pereira, Patrícia Valentão & Paula Andrade. (2018) Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety. International Journal of Molecular Sciences 19:6, pages 1668.
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Lin Zhu, Zhangting Wang, Lailai Wong, Yisheng He, Zhongzhen Zhao, Yang Ye, Peter P. Fu & Ge Lin. (2018) Contamination of hepatotoxic pyrrolizidine alkaloids in retail honey in China. Food Control 85, pages 484-494.
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Caroline T. Griffin, Aisling Sheehan, Martin Danaher & Ambrose Furey. 2017. Analysis of Food Toxins and Toxicants. Analysis of Food Toxins and Toxicants 267 318 .
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B.-E. Van Wyk, M.A. Stander & H.S. Long. (2017) Senecio angustifolius as the major source of pyrrolizidine alkaloid contamination of rooibos tea (Aspalathus linearis). South African Journal of Botany 110, pages 124-131.
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J. StrokaC.M. Maragos. (2016) Challenges in the analysis of multiple mycotoxins. World Mycotoxin Journal 9:5, pages 847-861.
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Matteo A. Lucchetti, Gaetan Glauser, Verena Kilchenmann, Arne Dübecke, Gudrun Beckh, Christophe Praz & Christina Kast. (2016) Pyrrolizidine Alkaloids from Echium vulgare in Honey Originate Primarily from Floral Nectar . Journal of Agricultural and Food Chemistry 64:25, pages 5267-5273.
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Lucatello Lorena, Merlanti Roberta, Rossi Alessandra, Montesissa Clara & Capolongo Francesca. (2015) Evaluation of Some Pyrrolizidine Alkaloids in Honey Samples from the Veneto Region (Italy) by LC-MS/MS. Food Analytical Methods 9:6, pages 1825-1836.
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Helge Neumann & Aiko Huckauf. (2015) Jakobs-Kreuzkraut (Senecio jacobaea): eine Ursache für Pyrrolizidin-Alkaloide im Sommerhonig?Tansy ragwort (Senecio jacobaea): a source of pyrrolizidine alkaloids in summer honey?. Journal für Verbraucherschutz und Lebensmittelsicherheit 11:2, pages 105-115.
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Clemens Allgaier & Stephanie Franz. (2015) Risk assessment on the use of herbal medicinal products containing pyrrolizidine alkaloids. Regulatory Toxicology and Pharmacology 73:2, pages 494-500.
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Inga Mädge, Luise Cramer, Ines Rahaus, Gerold Jerz, Peter Winterhalter & Till Beuerle. (2015) Pyrrolizidine alkaloids in herbal teas for infants, pregnant or lactating women. Food Chemistry 187, pages 491-498.
Crossref
Alexander Schenk, Beate Siewert, Stephan Toff & Jürgen Drewe. (2015) UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339). Journal of Chromatography B 997, pages 23-29.
Crossref
Nikoletta Jedlinszki & Dezső Csupor. (2015) A Validated, Rapid HPLC-ESI-MS/MS Method for the Determination of Lycopsamine. Natural Product Communications 10:7, pages 1934578X1501000.
Crossref
John A. Edgar, Russell J. Molyneux & Steven M. Colegate. (2014) Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease. Chemical Research in Toxicology 28:1, pages 4-20.
Crossref
Caroline T. Griffin, John O’Mahony, Martin Danaher & Ambrose Furey. (2014) Liquid Chromatography Tandem Mass Spectrometry Detection of Targeted Pyrrolizidine Alkaloids in Honeys Purchased within Ireland. Food Analytical Methods 8:1, pages 18-31.
Crossref
Brás Heleno de Oliveira. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry 1 20 .
Lizandra Czermainski Bretanha, Marcel Piovezan, Alysson Fernandez Vasques Sako, Moacir Geraldo Pizzolatti & Gustavo Amadeu Micke. (2014) Strategy for a Fast and Simple Method for Trace Determination of Senecionine and Senecionine N-Oxide in Honey Using LVI in HPLC-MS/MS. American Journal of Analytical Chemistry 05:10, pages 681-687.
Crossref
Michalina Oplatowska, Christopher T. Elliott, Anne-Catherine Huet, Mark McCarthy, Patrick P. J. Mulder, Christoph von Holst, Philippe Delahaut, Hans P. Van Egmond & Katrina Campbell. (2013) Development and validation of a rapid multiplex ELISA for pyrrolizidine alkaloids and their N-oxides in honey and feed. Analytical and Bioanalytical Chemistry 406:3, pages 757-770.
Crossref
Wim Reybroeck. 2014. Beekeeping for Poverty Alleviation and Livelihood Security. Beekeeping for Poverty Alleviation and Livelihood Security 481 506 .
Luise Cramer, Hans-Martin Schiebel, Ludger Ernst & Till Beuerle. (2013) Pyrrolizidine Alkaloids in the Food Chain: Development, Validation, and Application of a New HPLC-ESI-MS/MS Sum Parameter Method. Journal of Agricultural and Food Chemistry 61:47, pages 11382-11391.
Crossref
Colin Crews. 2013. Natural Products. Natural Products 1049 1068 .
B. Dusemund, A.E.M.F. Soffers & I.M.C.M. Rietjens. 2012. Chemical Contaminants and Residues in Food. Chemical Contaminants and Residues in Food 394 417 .
Irina I. Koleva, Teris A. van Beek, Ans E. M. F. Soffers, Birgit Dusemund & Ivonne M. C. M. Rietjens. (2011) Alkaloids in the human food chain – Natural occurrence and possible adverse effects. Molecular Nutrition & Food Research 56:1, pages 30-52.
Crossref
. (2011) Scientific Opinion on Pyrrolizidine alkaloids in food and feed. EFSA Journal 9:11.
Crossref

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