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Original Articles

An epimer of deoxynivalenol: purification and structure identification of 3-epi-deoxynivalenol

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Pages 1523-1530 | Received 07 May 2015, Accepted 07 Jul 2015, Published online: 06 Aug 2015

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Matthew G. Bakker, Daren W. Brown, Amy C. Kelly, Hye-Seon Kim, Cletus P. Kurtzman, Susan P. Mccormick, Kerry L. O’Donnell, Robert H. Proctor, Martha M. Vaughan & Todd J. Ward. (2018) Fusarium mycotoxins: a trans-disciplinary overview. Canadian Journal of Plant Pathology 40:2, pages 161-171.
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Articles from other publishers (25)

Yuang Tu, Shiqi Liu, Peiran Cai & Tizhong Shan. (2023) Global distribution, toxicity to humans and animals, biodegradation, and nutritional mitigation of deoxynivalenol: A review. Comprehensive Reviews in Food Science and Food Safety.
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Yuqian Tang, Dingna Xiao & Chendi Liu. (2023) Two-Step Epimerization of Deoxynivalenol by Quinone-Dependent Dehydrogenase and Candida parapsilosis ACCC 20221. Toxins 15:4, pages 286.
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Nadine Abraham, Kurt L. Schroeter, Yan Zhu, Jonathan Chan, Natasha Evans, Matthew S. Kimber, Jason Carere, Ting Zhou & Stephen Y. K. Seah. (2022) Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol. Scientific Reports 12:1.
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Hina Shanakhat, Susan P. McCormick, Mark Busman, Joseph O. Rich & Matthew G. Bakker. (2022) Modification of Deoxynivalenol by a Fungal Laccase Paired with Redox Mediator TEMPO. Toxins 14:8, pages 548.
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Xiu-Zhen Li, Yousef I. Hassan, Dion Lepp, Yan Zhu & Ting Zhou. (2022) 3-keto-DON, but Not 3-epi-DON, Retains the in Planta Toxicological Potential after the Enzymatic Biotransformation of Deoxynivalenol. International Journal of Molecular Sciences 23:13, pages 7230.
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Hua Yang, Ruxue Yan, Yue Li, Zhaoxin Lu, Xiaomei Bie, Haizhen Zhao, Fengxia Lu & Meirong Chen. (2022) Structure–Function Analysis of a Quinone-Dependent Dehydrogenase Capable of Deoxynivalenol Detoxification. Journal of Agricultural and Food Chemistry 70:22, pages 6764-6774.
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Honghai Zhang, Heng Zhang, Xing Qin, Xiaolu Wang, Yuan Wang, Yao Bin, Xiangming Xie, Fei Zheng & Huiying Luo. (2021) Biodegradation of Deoxynivalenol by Nocardioides sp. ZHH-013: 3-keto-Deoxynivalenol and 3-epi-Deoxynivalenol as Intermediate Products. Frontiers in Microbiology 12.
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Somayyeh Gandomkar, Raquel Rocha, Frieda A. Sorgenfrei, Lía Martínez Montero, Michael Fuchs & Wolfgang Kroutil. (2020) PQQ‐dependent Dehydrogenase Enables One‐pot Bi‐enzymatic Enantio‐convergent Biocatalytic Amination of Racemic sec ‐Allylic Alcohols . ChemCatChem 13:5, pages 1290-1293.
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Gang Wang, Yanxia Wang, Huizi Man, Yin-Won Lee, Jianrong Shi & Jianhong Xu. (2020) Metabolomics-guided analysis reveals a two-step epimerization of deoxynivalenol catalyzed by the bacterial consortium IFSN-C1. Applied Microbiology and Biotechnology 104:13, pages 6045-6056.
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Yousef I. Hassan, Jian Wei He, Dion Lepp & Ting Zhou. (2019) Understanding the Bacterial Response to Mycotoxins: The Transcriptomic Analysis of Deoxynivalenol-Induced Changes in Devosia mutans 17-2-E-8. Frontiers in Pharmacology 10.
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Gang Wang, Yanxia Wang, Fang Ji, Limei Xu, Mingzheng Yu, Jianrong Shi & Jianhong Xu. (2019) Biodegradation of deoxynivalenol and its derivatives by Devosia insulae A16. Food Chemistry 276, pages 436-442.
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S.A. TittlemierB. CramerC. Dall’AstaM.H. IhaV.M.T. LattanzioR.J. MaloneC. MaragosM. SolfrizzoM. Stranska-ZachariasovaJ. Stroka. (2019) Developments in mycotoxin analysis: an update for 2017-2018. World Mycotoxin Journal 12:1, pages 3-29.
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Jason Carere, Yousef I. Hassan, Dion Lepp & Ting Zhou. (2018) The enzymatic detoxification of the mycotoxin deoxynivalenol: identification of DepA from the DON epimerization pathway. Microbial Biotechnology 11:6, pages 1106-1111.
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Jason Carere, Yousef I. Hassan, Dion Lepp & Ting Zhou. (2018) The Identification of DepB: An Enzyme Responsible for the Final Detoxification Step in the Deoxynivalenol Epimerization Pathway in Devosia mutans 17-2-E-8. Frontiers in Microbiology 9.
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Yan Zhu, Yousef I. Hassan, Suqin Shao & Ting Zhou. (2018) Employing immuno-affinity for the analysis of various microbial metabolites of the mycotoxin deoxynivalenol. Journal of Chromatography A 1556, pages 81-87.
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Y.I. Hassan & T. Zhou. (2018) Addressing the mycotoxin deoxynivalenol contamination with soil-derived bacterial and enzymatic transformations targeting the C3 carbon. World Mycotoxin Journal 11:1, pages 101-112.
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Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Sarah De Saeger, Gunnar Sundstøl Eriksen, Peter Farmer, Jean‐Marc Fremy, Yun Yun Gong, Karsten Meyer, Hanspeter Naegeli, Dominique Parent‐Massin, Ivonne Rietjens, Hans van Egmond, Andrea Altieri, Mari Eskola, Petra Gergelova, Luisa Ramos Bordajandi, Bistra Benkova, Barbara Dörr, Athanasios Gkrillas, Nicklas Gustavsson, Mathijs van Manen & Lutz Edler. (2017) Risks to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed. EFSA Journal 15:9.
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Yousef I. Hassan, Jian Wei He, Norma Perilla, KaiJie Tang, Petr Karlovsky & Ting Zhou. (2017) The enzymatic epimerization of deoxynivalenol by Devosia mutans proceeds through the formation of 3-keto-DON intermediate. Scientific Reports 7:1.
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Nina Wilson, Nicole McMaster, Dash Gantulga, Cara Soyars, Susan McCormick, Ken Knott, Ryan Senger & David Schmale. (2017) Modification of the Mycotoxin Deoxynivalenol Using Microorganisms Isolated from Environmental Samples. Toxins 9:4, pages 141.
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Yan Zhu, Yousef Hassan, Dion Lepp, Suqin Shao & Ting Zhou. (2017) Strategies and Methodologies for Developing Microbial Detoxification Systems to Mitigate Mycotoxins. Toxins 9:4, pages 130.
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Ilse Vanhoutte, Laura De Mets, Marthe De Boevre, Valdet Uka, José Di Mavungu, Sarah De Saeger, Leen De Gelder & Kris Audenaert. (2017) Microbial Detoxification of Deoxynivalenol (DON), Assessed via a Lemna minor L. Bioassay, through Biotransformation to 3-epi-DON and 3-epi-DOM-1. Toxins 9:2, pages 63.
Crossref
Yousef Hassan, Honghui Zhu, Yan Zhu & Ting Zhou. (2016) Beyond Ribosomal Binding: The Increased Polarity and Aberrant Molecular Interactions of 3-epi-deoxynivalenol. Toxins 8:9, pages 261.
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Alix Pierron, Sabria Mimoun, Leticia S. Murate, Nicolas Loiseau, Yannick Lippi, Ana-Paula F. L. Bracarense, Gerd Schatzmayr, Jian Wei He, Ting Zhou, Wulf-Dieter Moll & Isabelle P. Oswald. (2016) Microbial biotransformation of DON: molecular basis for reduced toxicity. Scientific Reports 6:1.
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Jian Wei He, Yousef I. Hassan, Norma Perilla, Xiu-Zhen Li, Greg J. Boland & Ting Zhou. (2016) Bacterial Epimerization as a Route for Deoxynivalenol Detoxification: the Influence of Growth and Environmental Conditions. Frontiers in Microbiology 7.
Crossref
Jian Wei He, Genevieve S. Bondy, Ting Zhou, Don Caldwell, Greg J. Boland & Peter M. Scott. (2015) Toxicology of 3-epi-deoxynivalenol, a deoxynivalenol-transformation product by Devosia mutans 17-2-E-8. Food and Chemical Toxicology 84, pages 250-259.
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