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Original Articles

Pyrrolizidine alkaloids in food and feed on the Belgian market

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Pages 1939-1951 | Received 16 Apr 2015, Accepted 17 Aug 2015, Published online: 15 Oct 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Ana Catarina Sousa, Cláudia Ribeiro, Virgínia M.F. Gonçalves, Inês Pádua & Sandra Leal. (2023) Chromatographic Methods for Detection and Quantification of Pyrrolizidine Alkaloids in Flora, Herbal Medicines, and Food: An Overview. Critical Reviews in Analytical Chemistry 0:0, pages 1-25.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2020) Application of the sum parameter method for the determination of pyrrolizidine alkaloids in teas. Food Additives & Contaminants: Part A 37:4, pages 622-633.
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Christina Kast, Verena Kilchenmann, Hans Reinhard, Benoit Droz, Matteo Angelo Lucchetti, Arne Dübecke, Gudrun Beckh & Otmar Zoller. (2018) Chemical fingerprinting identifies Echium vulgare, Eupatorium cannabinum and Senecio spp. as plant species mainly responsible for pyrrolizidine alkaloids in bee-collected pollen. Food Additives & Contaminants: Part A 35:2, pages 316-327.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2017) Determination of pyrrolizidine alkaloids in selected feed materials with gas chromatography-mass spectrometry. Food Additives & Contaminants: Part A 34:5, pages 853-863.
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Articles from other publishers (32)

Adrián Fuente-Ballesteros, Ondrej Brabenec, Aristeidis S. Tsagkaris, Ana M. Ares, Jana Hajslova & José Bernal. (2024) Comprehensive overview of the analytical methods for determining pyrrolizidine alkaloids and their derived oxides in foods. Journal of Food Composition and Analysis 125, pages 105758.
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Ke Zan, Zhao Wang, Ying Wang, Jian-Dong Yu, Hong-Yu Jin & Shuang-Cheng Ma. (2023) Distribution, determination method, risk assessment, and strategy of exogenous pyrrolizidine alkaloids in tea. Pharmacological Research - Modern Chinese Medicine 8, pages 100277.
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Mariantonietta Peloso, Gaetan Minkoumba Sonfack, Sandra Paduano, Michele De Martino, Barbara De Santis & Elisabetta Caprai. (2023) Pyrrolizidine Alkaloids in Food on the Italian Market. Molecules 28:14, pages 5346.
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Ailsa G. Hardie, Kagisho Olifant, J.F.Naude Smith & J.Eduard Hoffman. (2023) Scientific evidence of soil transfer of pyrrolizidine alkaloids originating from weed species to rooibos tea. South African Journal of Botany 157, pages 159-166.
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Paola Roncada, Gloria Isani, Mariantonietta Peloso, Thomas Dalmonte, Stefania Bonan & Elisabetta Caprai. (2023) Pyrrolizidine Alkaloids from Monofloral and Multifloral Italian Honey. International Journal of Environmental Research and Public Health 20:7, pages 5410.
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Bowen Gong, Shiyu Zhang, Xin Wang, Guangyun Ran, Xiaohong Zhang, Jing Xi, Zhenna Gao, Yuyang Lei, Jie Pan, Ying Liu, Yang Luan, Xinyu Zhang, Ying Peng, Weiwei Li & Jiang Zheng. (2023) Inflammation Intensifies Monocrotaline-Induced Liver Injury. Journal of Agricultural and Food Chemistry.
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Adriana L. Silva, Joana L. Oliveira, Ravena P. do Nascimento, Letícia O. Santos, Fillipe M. de Araújo, Balbino L. dos Santos, Rejane C. Santana, Eduardo Luiz T. Moreira, Maria José M. Batatinha, Iura M. Alves, Eudes S. Velozo, Mauricio M. Victor, Adriano M. Assis, Roberto F. Almeida, Diogo O.G. de Souza, Victor Diógenes A. Silva & Silvia L. Costa. (2023) Monocrotaline induces acutely cerebrovascular lesions, astrogliosis and neuronal degeneration associated with behavior changes in rats: A model of vascular damage in perspective. NeuroToxicology 94, pages 59-70.
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Marianna Martinello, Chiara Manzinello, Albino Gallina & Franco Mutinelli. (2022) In‐house validation and application of UHPLC‐MS/MS method for the quantification of pyrrolizidine and tropane alkaloids in commercial honey bee‐collected pollen, teas and herbal infusions purchased on Italian market in 2019–2020 referring to recent European Union regulations. International Journal of Food Science & Technology 57:12, pages 7505-7516.
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Lisa Monika Klein, Angelika Miriam Gabler, Michael Rychlik, Christoph Gottschalk & Florian Kaltner. (2022) A sensitive LC–MS/MS method for isomer separation and quantitative determination of 51 pyrrolizidine alkaloids and two tropane alkaloids in cow’s milk. Analytical and Bioanalytical Chemistry 414:28, pages 8107-8124.
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Martins Jansons, Deniss Fedorenko, Romans Pavlenko, Zane Berzina & Vadims Bartkevics. (2022) Nanoflow liquid chromatography mass spectrometry method for quantitative analysis and target ion screening of pyrrolizidine alkaloids in honey, tea, herbal tinctures, and milk. Journal of Chromatography A 1676, pages 463269.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2022) Simultaneous determination of pyrrolizidine and tropane alkaloids in honey by liquid chromatography–mass spectrometry. Journal of Veterinary Research 66:2, pages 235-243.
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Natalia Casado, Begoña Fernández-Pintor, Sonia Morante-Zarcero & Isabel Sierra. (2022) Quick and Green Microextraction of Pyrrolizidine Alkaloids from Infusions of Mallow, Calendula, and Hibiscus Flowers Using Ultrahigh-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry Analysis. Journal of Agricultural and Food Chemistry 70:25, pages 7826-7841.
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Natalia Casado, Sonia Morante-Zarcero & Isabel Sierra. (2022) The concerning food safety issue of pyrrolizidine alkaloids: An overview. Trends in Food Science & Technology 120, pages 123-139.
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Ziqi Wang, Haolei Han, Chen Wang, Qinqin Zheng, Hongping Chen, Xiangchun Zhang & Ruyan Hou. (2021) Hepatotoxicity of Pyrrolizidine Alkaloid Compound Intermedine: Comparison with Other Pyrrolizidine Alkaloids and Its Toxicological Mechanism. Toxins 13:12, pages 849.
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Els Van Pamel, Jean Henrottin, Christof Van Poucke, Nathalie Gillard & Els Daeseleire. (2021) Multi-Class UHPLC-MS/MS Method for Plant Toxins and Cyanotoxins in Food Supplements and Application for Belgian Market Samples. Planta Medica 87:12/13, pages 1069-1079.
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Bart Huybrechts, Svetlana V. Malysheva & Julien Masquelier. (2021) A Targeted UHPLC-MS/MS Method Validated for the Quantification of Ergot Alkaloids in Cereal-Based Baby Food from the Belgian Market. Toxins 13:8, pages 531.
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E. Xiang, Qi Guo, Yong-guo Dai, Xiao-xiang Sun, Jie Liu, Yan-qing Wang, Shuai-kai Qiu, Yan-juan Zhao, Hui Wang & Yu Guo. (2020) Female-specific activation of pregnane X receptor mediates sex difference in fetal hepatotoxicity by prenatal monocrotaline exposure. Toxicology and Applied Pharmacology, pages 115137.
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C. Rückert, I. Emmerich, R. Hertzsch & I. Vervuert. (2018) Pyrrolizidine alkaloids in commercial feedstuffs for horses. Equine Veterinary Journal 51:4, pages 495-499.
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Jia-Yin CHEN, Jürgen Brockmöller, Mladen V. Tzvetkov, Li-Jun WANG & Xi-Jing CHEN. (2019) An in vitro study on interaction of anisodine and monocrotaline with organic cation transporters of the SLC22 and SLC47 families. Chinese Journal of Natural Medicines 17:7, pages 490-497.
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Yu Guo, Di Xiao, Xiaojing Yang, Jiang Zheng, Shuwei Hu, Panfeng Wu, Xiaoxia Li, Hao Kou & Hui Wang. (2019) Prenatal exposure to pyrrolizidine alkaloids induced hepatotoxicity and pulmonary injury in fetal rats. Reproductive Toxicology 85, pages 34-41.
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Christina KastMatteo A. Lucchetti. 2019. Chemical hazards in foods of animal origin. Chemical hazards in foods of animal origin 529 542 .
Oliver Keuth, Hans-Ulrich Humpf & Peter Fürst. 2019. Encyclopedia of Food Chemistry. Encyclopedia of Food Chemistry 348 355 .
Chuanhui Ma, Yang Liu, Lin Zhu, Hong Ji, Xun Song, Hui Guo & Tao Yi. (2018) Determination and regulation of hepatotoxic pyrrolizidine alkaloids in food: A critical review of recent research. Food and Chemical Toxicology 119, pages 50-60.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2018) Use of a new LC-MS method for the determination of pyrrolizidine alkaloids in feeds. Journal of Veterinary Research 62:2, pages 183-191.
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Ewelina Kowalczyk & Krzysztof Kwiatek. (2018) Pyrrolizidine alkaloids in honey: determination with liquid chromatography-mass spectrometry method. Journal of Veterinary Research 62:2, pages 173-181.
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Katarína Kromerová & Vladimír Bencko. (2018) Selected plant toxins in honey and their health effects. Hygiena 63:2, pages 50-53.
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Xia Li, Xiaojing Yang, E Xiang, Jinyuan Luo, Shuaikai Qiu, Yan Fang, Li Zhang, Yu Guo, Jiang Zheng & Hui Wang. (2018) Maternal-Fetal Disposition and Metabolism of Retrorsine in Pregnant Rats. Drug Metabolism and Disposition 46:4, pages 422-428.
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Marianna Martinello, Alice Borin, Roberto Stella, Davide Bovo, Giancarlo Biancotto, Albino Gallina & Franco Mutinelli. (2017) Development and validation of a QuEChERS method coupled to liquid chromatography and high resolution mass spectrometry to determine pyrrolizidine and tropane alkaloids in honey. Food Chemistry 234, pages 295-302.
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B.-E. Van Wyk, M.A. Stander & H.S. Long. (2017) Senecio angustifolius as the major source of pyrrolizidine alkaloid contamination of rooibos tea (Aspalathus linearis). South African Journal of Botany 110, pages 124-131.
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Shimon Barel, Dani Elad, Olga Cuneah & Jakob A Shimshoni. (2017) The new Israeli feed safety law: challenges in relation to animal and public health. Journal of the Science of Food and Agriculture 97:4, pages 1073-1083.
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Jeremy Robertson & Kiri Stevens. (2017) Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis. Natural Product Reports 34:1, pages 62-89.
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Matteo A. Lucchetti, Gaetan Glauser, Verena Kilchenmann, Arne Dübecke, Gudrun Beckh, Christophe Praz & Christina Kast. (2016) Pyrrolizidine Alkaloids from Echium vulgare in Honey Originate Primarily from Floral Nectar . Journal of Agricultural and Food Chemistry 64:25, pages 5267-5273.
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