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Original Articles

Risk assessment of plant food supplements and other herbal products containing aristolochic acids using the margin of exposure (MOE) approach

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Pages 135-144 | Received 12 Oct 2016, Accepted 13 Nov 2016, Published online: 16 Dec 2016

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G. Vo Van Regnault, M. C. Costa, A. Adanić Pajić, A. P. Bico, S. Bischofova, U. Blaznik, F. Menniti-Ippolito, K. Pilegaard, C. Rodrigues & I. Margaritis. (2022) The need for European harmonization of Nutrivigilance in a public health perspective: a comprehensive review. Critical Reviews in Food Science and Nutrition 62:29, pages 8230-8246.
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Gerhard Prinsloo, Francois Steffens, Jacques Vervoort & Ivonne M.C.M. Rietjens. (2019) Risk assessment of herbal supplements containing ingredients that are genotoxic and carcinogenic. Critical Reviews in Toxicology 49:7, pages 567-579.
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Bashir Mohammed Abubakar, Faezah Mohd Salleh, Mohd Shahir Shamsir Omar & Alina Wagiran. (2018) Assessing product adulteration of Eurycoma longifolia (Tongkat Ali) herbal medicinal product using DNA barcoding and HPLC analysis. Pharmaceutical Biology 56:1, pages 368-377.
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Articles from other publishers (11)

Cheng-I. Liao, Hua-Chang Fang, Po-Tsang Lee, Chih-Yang Hsu, Chien-Liang Chen, Chien-Wei Huang, Xin-You Chen, Shih-Hsiang Ou, Chun-Teng Tsai & Kang-Ju Chou. (2023) Trends in the incidence of urothelial carcinoma in Taiwan after the ban on aristolochic acid-containing Chinese herbal preparations, 2001–2018: a national population-based cohort study. Journal of Cancer Research and Clinical Oncology 149:11, pages 8201-8211.
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Piao Luo, Jiayun Chen, Qian Zhang, Fei Xia, Chen Wang, Yunmeng Bai, Huan Tang, Dandan Liu, Liwei Gu, Qingfeng Du, Wei Xiao, Chuanbin Yang & Jigang Wang. (2022) Dissection of cellular and molecular mechanisms of aristolochic acid-induced hepatotoxicity via single-cell transcriptomics. Precision Clinical Medicine 5:4.
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Tetyana Kobets, Benjamin P. C. Smith & Gary M. Williams. (2022) Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk. Foods 11:18, pages 2828.
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Nur Azra M. Pauzi, Manraj S. Cheema, Amin Ismail, Ahmad Rohi Ghazali & Rozaini Abdullah. (2022) Safety assessment of natural products in Malaysia: current practices, challenges, and new strategies. Reviews on Environmental Health 37:2, pages 169-179.
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Kamil Jurowski & Mirosław Krośniak. (2022) The Human Health Risk Assessment of Heavy Metals Impurities (Cd and Pb) in Herbal Medicinal Products as Menthae piperitae tinctura (Mentha × piperita L., folium) Available in Pharmacies from Poland. Toxics 10:5, pages 273.
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Mohanarangam Thangavelu, Asmaa Ismail, Ahmed Zakaria, Hazem Elmansy, Walid Shahrour, Owen Prowse & Ahmed Kotb. (2022) Aristolochic acid: What urologists should know. Archivio Italiano di Urologia e Andrologia 94:1, pages 123-125.
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Dan Xu, Lizi Yin, Juchun Lin, Hualin Fu, Xi Peng, Lijen Chang, Yilei Zheng, Xiaoling Zhao & Gang Shu. (2021) Aristolochic Acid I-Induced Hepatotoxicity in Tianfu Broilers Is Associated with Oxidative-Stress-Mediated Apoptosis and Mitochondrial Damage. Animals 11:12, pages 3437.
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Mohammed Bourhia, Ayoub Lahmadi, Hafid Achtak, Ayoub Touis, Jamal Elbrahmi, Riaz Ullah, Abdelaaty A. Shahat, Hafiz Majid Mahmood, Souad Aboudkhil, Laila Benbacer & Naima Khlil. (2019) Phytochemical Analysis and Toxicity Study of Aristolochia paucinervis Rhizomes Decoction Used in Moroccan Alternative Medicine: Histopathological and Biochemical Profiles . Evidence-Based Complementary and Alternative Medicine 2019, pages 1-11.
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Jiayin Han, Zhong Xian, Yushi Zhang, Jing Liu & Aihua Liang. (2019) Systematic Overview of Aristolochic Acids: Nephrotoxicity, Carcinogenicity, and Underlying Mechanisms. Frontiers in Pharmacology 10.
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Tiziana Sgamma, Eva Masiero, Purvi Mali, Maslinda Mahat & Adrian Slater. (2018) Sequence-Specific Detection of Aristolochia DNA – A Simple Test for Contamination of Herbal Products. Frontiers in Plant Science 9.
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G. Prinsloo & N. Nogemane. (2018) The effects of season and water availability on chemical composition, secondary metabolites and biological activity in plants. Phytochemistry Reviews 17:4, pages 889-902.
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