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Journal of Extracellular Vesicles Volume 8, 2019 - Issue 1
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Research Article

Systematic characterization of extracellular vesicle sorting domains and quantification at the single molecule – single vesicle level by fluorescence correlation spectroscopy and single particle imaging

Giulia CorsoDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, SwedenORCID Iconhttps://orcid.org/0000-0002-1145-0862View further author information
ORCID Icon,
Wolf HeusermannNovartis Institutes for Biomedical Research, Basel, Switzerland;Imaging Core Facility, Biozentrum, University of Basel, Basel, SwitzerlandView further author information
,
Dominic TrojerNovartis Institutes for Biomedical Research, Basel, SwitzerlandView further author information
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André GörgensDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden;Institute for Transfusion Medicine, University Hospital Essen, Essen, GermanyView further author information
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Emmanuelle SteibNovartis Institutes for Biomedical Research, Basel, Switzerland;Department of Cell Biology, Sciences III, University of Geneva, GenevaSwitzerlandView further author information
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Johannes VosholNovartis Institutes for Biomedical Research, Basel, SwitzerlandView further author information
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Alexandra GraffFacility for advanced imaging and microscopy, Friedrich Miescher Institute for Biomedical Research, Basel, SwitzerlandORCID Iconhttps://orcid.org/0000-0001-9312-9230View further author information
ORCID Icon,
Christel GenoudFacility for advanced imaging and microscopy, Friedrich Miescher Institute for Biomedical Research, Basel, SwitzerlandView further author information
,
Yi LeeDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden;Department of Cancer and Stratified Oncology 5, A*star Genome Institute of Singapore, SingaporeView further author information
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Justin HeanNovartis Institutes for Biomedical Research, Basel, SwitzerlandView further author information
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Joel Z. NordinDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, SwedenView further author information
,
Oscar P.B. WiklanderDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, SwedenView further author information
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Samir El AndaloussiDepartment of Laboratory Medicine, Karolinska Institutet, Stockholm, SwedenCorrespondence[email protected] [email protected]
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Nicole Meisner-KoberNovartis Institutes for Biomedical Research, Basel, Switzerland;Department of Biosciences, University of Salzburg, Salzburg, AustriaView further author information
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Article: 1663043 | Received 02 Apr 2019, Accepted 21 Aug 2019, Published online: 18 Sep 2019

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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Maximilian Richter, Pieter Vader & Gregor Fuhrmann. (2021) Approaches to surface engineering of extracellular vesicles. Advanced Drug Delivery Reviews 173, pages 416-426.
Crossref
Teran Cloet, Nikan Momenbeitollahi & Huiyan Li. (2021) Recent advances on protein-based quantification of extracellular vesicles. Analytical Biochemistry 622, pages 114168.
Crossref
Olavi Reinsalu, Anneli Samel, Elen Niemeister & Reet Kurg. (2021) MAGEA4 Coated Extracellular Vesicles Are Stable and Can Be Assembled In Vitro. International Journal of Molecular Sciences 22:10, pages 5208.
Crossref
Federico Colombo, Erienne G. Norton & Emanuele Cocucci. (2021) Microscopy approaches to study extracellular vesicles. Biochimica et Biophysica Acta (BBA) - General Subjects 1865:4, pages 129752.
Crossref
Sara Cavallaro, Federico Pevere, Fredrik Stridfeldt, André Görgens, Carolina Paba, Siddharth S. Sahu, Doste R. Mamand, Dhanu Gupta, Samir El Andaloussi, Jan Linnros & Apurba Dev. (2021) Multiparametric Profiling of Single Nanoscale Extracellular Vesicles by Combined Atomic Force and Fluorescence Microscopy: Correlation and Heterogeneity in Their Molecular and Biophysical Features. Small 17:14.
Crossref
Tanina Arab, Emily R. Mallick, Yiyao Huang, Liang Dong, Zhaohao Liao, Zezhou Zhao, Olesia Gololobova, Barbara Smith, Norman J. Haughey, Kenneth J. Pienta, Barbara S. Slusher, Patrick M. Tarwater, Juan Pablo Tosar, Angela M. Zivkovic, Wyatt N. Vreeland, Michael E. Paulaitis & Kenneth W. Witwer. (2021) Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms. Journal of Extracellular Vesicles 10:6.
Crossref
Elisa Lázaro-Ibáñez, Farid N. Faruqu, Amer F. Saleh, Andreia M. Silva, Julie Tzu-Wen Wang, Janusz Rak, Khuloud T. Al-Jamal & Niek Dekker. (2021) Selection of Fluorescent, Bioluminescent, and Radioactive Tracers to Accurately Reflect Extracellular Vesicle Biodistribution in Vivo . ACS Nano 15:2, pages 3212-3227.
Crossref
Sören Kuypers, Nick Smisdom, Isabel Pintelon, Jean‐Pierre Timmermans, Marcel Ameloot, Luc Michiels, Jelle Hendrix & Baharak Hosseinkhani. (2021) Unsupervised Machine Learning‐Based Clustering of Nanosized Fluorescent Extracellular Vesicles. Small 17:5.
Crossref
Wumei Wei, Qiang Ao, Xiaohong Wang, Yue Cao, Yanying Liu, Song Guo Zheng & Xiaohong Tian. (2021) Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine. Frontiers in Pharmacology 11.
Crossref
Hyosuk Kim, Eun Hye Kim, Gijung Kwak, Sung-Gil Chi, Sun Hwa Kim & Yoosoo Yang. (2020) Exosomes: Cell-Derived Nanoplatforms for the Delivery of Cancer Therapeutics. International Journal of Molecular Sciences 22:1, pages 14.
Crossref
Jina Ko, Yongcheng Wang, Jonathan C. T. Carlson, Angela Marquard, Jeremy Gungabeesoon, Alain Charest, David Weitz, Mikael J. Pittet & Ralph Weissleder. (2020) Single Extracellular Vesicle Protein Analysis Using Immuno‐Droplet Digital Polymerase Chain Reaction Amplification. Advanced Biosystems 4:12, pages 1900307.
Crossref
Srujan Gandham, Xianyi Su, Jacqueline Wood, Angela L. Nocera, Sarath Chandra Alli, Lara Milane, Alan Zimmerman, Mansoor Amiji & Alexander R. Ivanov. (2020) Technologies and Standardization in Research on Extracellular Vesicles. Trends in Biotechnology 38:10, pages 1066-1098.
Crossref
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Crossref
Tamás Matusek, Julien Marcetteau & Pascal P. Thérond. (2020) Functions of Wnt and Hedgehog-containing extracellular vesicles in development and disease. Journal of Cell Science 133:18.
Crossref
Renee V Goreham, Zeineb Ayed, Zarinah M Amin & Garima Dobhal. (2020) The future of quantum dot fluorescent labelling of extracellular vesicles for biomedical applications. Nano Futures 4:2, pages 022001.
Crossref
Pablo Reclusa, Peter Verstraelen, Simona Taverna, Muthukumar Gunasekaran, Marzia Pucci, Isabel Pintelon, Nathalie Claes, Diego de Miguel-Pérez, Riccardo Alessandro, Sara Bals, Sunjay Kaushal & Christian Rolfo. (2020) Improving extracellular vesicles visualization: From static to motion. Scientific Reports 10:1.
Crossref
Su Wang, Adeel Khan, Rongrong Huang, Shiyi Ye, Kaili Di, Tao Xiong & Zhiyang Li. (2020) Recent advances in single extracellular vesicle detection methods. Biosensors and Bioelectronics 154, pages 112056.
Crossref
Yong Weon Yi, Jun Ho Lee, Sang-Yeob Kim, Chan-Gi Pack, Dae Hyun Ha, Sang Rae Park, Jinkwon Youn & Byong Seung Cho. (2020) Advances in Analysis of Biodistribution of Exosomes by Molecular Imaging. International Journal of Molecular Sciences 21:2, pages 665.
Crossref
Benjamin Mary, Shima Ghoroghi, Vincent Hyenne & Jacky G. Goetz. 2020. Extracellular vesicles. Extracellular vesicles 243 275 .
Sara Elgamal, Federico Colombo, Francesca Cottini, John C. Byrd & Emanuele Cocucci. 2020. Extracellular vesicles. Extracellular vesicles 79 107 .

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