5,174
Views
47
CrossRef citations to date
0
Altmetric
Short Communication

Single molecule characterization of individual extracellular vesicles from pancreatic cancer

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, , , , , , , , , & ORCID Icon show all
Article: 1685634 | Received 02 Apr 2019, Accepted 21 Oct 2019, Published online: 04 Nov 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Chenxuan Bao, Huayuan Xiang, Qiaoqiao Chen, Yuxue Zhao, Qianqian Gao, Feng Huang & Lingxiang Mao. (2023) A Review of Labeling Approaches Used in Small Extracellular Vesicles Tracing and Imaging. International Journal of Nanomedicine 18, pages 4567-4588.
Read now
Joshua A. Welsh, Edwin van der Pol, Britta A. Bettin, David R. F. Carter, An Hendrix, Metka Lenassi, Marc-André Langlois, Alicia Llorente, Arthur S. van de Nes, Rienk Nieuwland, Vera Tang, Lili Wang, Kenneth W. Witwer & Jennifer C. Jones. (2020) Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration. Journal of Extracellular Vesicles 9:1.
Read now
Kevin Burbidge, Virginia Zwikelmaier, Ben Cook, Michael M. Long, Barak Balva, Michael Lonigro, Grace Ispas, David J. Rademacher & Edward M. Campbell. (2020) Cargo and cell-specific differences in extracellular vesicle populations identified by multiplexed immunofluorescent analysis. Journal of Extracellular Vesicles 9:1.
Read now

Articles from other publishers (44)

Karama Asleh, Valerie Dery, Catherine Taylor, Michelle Davey, Marie-Ange Djeungoue-Petga & Rodney J. Ouellette. (2023) Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology. Biomarker Research 11:1.
Crossref
Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Luong T. H. Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, Kim Truc Nguyen, Karunya Albert, Minh‐Dao Duong‐Thi, Nicole Walters, Kwang Joo Kwak, Min Jin Yoon, Hong Li, Jacob Doon‐Ralls, Colin L. Hisey, Daeyong Lee, Yifan Wang, Jonghoon Ha, Kelsey Scherler, Shannon Fallen, Inyoul Lee, Andre F. Palmer, Wen Jiang, Setty M. Magaña, Kai Wang, Betty Y. S. Kim, L. James Lee & Eduardo Reátegui. (2023) Engineering a tunable micropattern‐array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ. Journal of Extracellular Vesicles 12:11.
Crossref
Jie Zhang, Jiacheng Wu, Guanzhao Wang, Luxuan He, Ziwei Zheng, Minhao Wu & Yuanqing Zhang. (2023) Extracellular Vesicles: Techniques and Biomedical Applications Related to Single Vesicle Analysis. ACS Nano.
Crossref
Andras Saftics, Sarah Abuelreich, Eugenia Romano, Ima Ghaeli, Nan Jiang, Michail Spanos, Kathleen M. Lennon, Gagandeep Singh, Saumya Das, Kendall Van Keuren‐Jensen & Tijana Jovanovic‐Talisman. (2023) Single Extracellular VEsicle Nanoscopy. Journal of Extracellular Vesicles 12:7.
Crossref
Zhouxiao Li, Yiyang Gao, Yang Cao, Feifan He, Runyi Jiang, Hanyuan Liu, Hongzhou Cai & Tao Zan. (2023) Extracellular RNA in melanoma: Advances, challenges, and opportunities. Frontiers in Cell and Developmental Biology 11.
Crossref
Sujitha Puthukodan, Martina Hofmann, Mario Mairhofer, Hannah Janout, Jonas Schurr, Fabian Hauser, Christoph Naderer, Johannes Preiner, Stephan Winkler, Dmitry Sivun & Jaroslaw Jacak. (2023) Purification Analysis, Intracellular Tracking, and Colocalization of Extracellular Vesicles Using Atomic Force and 3D Single-Molecule Localization Microscopy. Analytical Chemistry 95:14, pages 6061-6070.
Crossref
Seung-Ryoung Jung, James Kim, Lucia Vojtech, Joshua C. Vaughan & Daniel T. Chiu. (2023) Error-Correction Method for High-Throughput Sizing of Nanoscale Vesicles with Single-Molecule Localization Microscopy. The Journal of Physical Chemistry B 127:12, pages 2701-2707.
Crossref
Roger Riera, Emmanouil Archontakis, Glenn Cremers, Tom de Greef, Peter Zijlstra & Lorenzo Albertazzi. (2023) Precision and Accuracy of Receptor Quantification on Synthetic and Biological Surfaces Using DNA-PAINT. ACS Sensors 8:1, pages 80-93.
Crossref
Lei Qiu, Xingzhu Liu, Libo Zhu, Liqiang Luo, Na Sun & Renjun Pei. (2023) Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis. Biosensors 13:1, pages 129.
Crossref
Marta Garcia-Contreras & AvneshS Thakor. (2023) Extracellular vesicles in Alzheimer’s disease: from pathology to therapeutic approaches. Neural Regeneration Research 18:1, pages 18.
Crossref
Jugal Suthar, Marissa Taub, Randy P. Carney, Gareth R. Williams & Stefan Guldin. (2022) Recent developments in biosensing methods for extracellular vesicle protein characterization. WIREs Nanomedicine and Nanobiotechnology 15:1.
Crossref
Charles P. Hinzman, Meth Jayatilake, Sunil Bansal, Brian L. Fish, Yaoxiang Li, Yubo Zhang, Shivani Bansal, Michael Girgis, Anton Iliuk, Xiao Xu, Jose A. Fernandez, John H. Griffin, Elizabeth A. Ballew, Keith Unger, Marjan Boerma, Meetha Medhora & Amrita K. Cheema. (2022) An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure. Journal of Translational Medicine 20:1.
Crossref
Wei Zhang, Douglas H. Campbell, Bradley J. Walsh, Nicolle H. Packer, Dingbin Liu & Yuling Wang. (2022) Cancer-derived small extracellular vesicles: emerging biomarkers and therapies for pancreatic ductal adenocarcinoma diagnosis/prognosis and treatment. Journal of Nanobiotechnology 20:1.
Crossref
Xiangdong Gongye, Ming Tian, Peng Xia, Chengmin Qu, Zhang Chen, Jigang Wang, Qian Zhu, Zhijie Li & Yufeng Yuan. (2022) Multi-omics analysis revealed the role of extracellular vesicles in hepatobiliary & pancreatic tumor. Journal of Controlled Release 350, pages 11-25.
Crossref
Luong T. H. Nguyen, Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Kwang Joo Kwak, Tamio Okimoto, Joseph Amann, Min Jin Yoon, Takehito Shukuya, Chi‐Ling Chiang, Nicole Walters, Yifan Ma, Donald Belcher, Hong Li, Andre F. Palmer, David P. Carbone, L. James Lee & Eduardo Reátegui. (2022) An immunogold single extracellular vesicular RNA and protein ( Au SERP) biochip to predict responses to immunotherapy in non‐small cell lung cancer patients . Journal of Extracellular Vesicles 11:9.
Crossref
Scott Ferguson, Katherine S. Yang & Ralph Weissleder. (2022) Single extracellular vesicle analysis for early cancer detection. Trends in Molecular Medicine 28:8, pages 681-692.
Crossref
Bogdan Mateescu, Jennifer C. Jones, Roger P. Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T. Chiu, Robert J. Coffey, Saumya Das, Peter De Hoff, Andrew deMello, Crislyn D’Souza-Schorey, David Elashoff, Kiarash R. Eliato, Jeffrey L. Franklin, David J. Galas, Mark B. Gerstein, Ionita H. Ghiran, David B. Go, Stephen Gould, Tristan R. Grogan, James N. Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K. Jeppesen, Tijana Jovanovic-Talisman, Betty Y.S. Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R. Kitchen, Vaughan Knouse, Emily L. LaPlante, Carlito B. Lebrilla, L. James Lee, Kathleen M. Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L. Maddox, Kyle McCarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P. De Oliveira Junior, Michael E. Paulaitis, Tuan Anh Phu, Robert L. Raffai, Eduardo Reátegui, Matthew E. Roth, David A. Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K. Sood, Stavros Stavrakis, Alessandra Stürchler, Muneesh Tewari, Juan P. Tosar, Alexander K. Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C. Vickers, Lucia Vojtech, Wyatt N. Vreeland, Ceming Wang, Kai Wang, ZeYu Wang, Joshua A. Welsh, Kenneth W. Witwer, David T.W. Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikołaj P. Zaborowski, Chenguang Zhang, Qin Zhang, Angela M. Zivkovic & Louise C. Laurent. (2022) Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research. iScience 25:8, pages 104653.
Crossref
Julia Bauzá‐Martinez, Gad Armony, Matti F. Pronker & Wei Wu. (2022) Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL). Journal of Extracellular Vesicles 11:8.
Crossref
Kathleen M. Lennon, Andras Saftics, Sarah Abuelreich, Parul Sahu, H. Immo Lehmann, Adam L. Maddox, Reem Bagabas, James L. Januzzi, Kendall Van Keuren‐Jensen, Ravi Shah, Saumya Das & Tijana Jovanovic‐Talisman. (2022) Cardiac troponin T in extracellular vesicles as a novel biomarker in human cardiovascular disease. Clinical and Translational Medicine 12:8.
Crossref
Ting Wang, Yanlong Xing, Ziyi Cheng & Fabiao Yu. (2022) Analysis of single extracellular vesicles for biomedical applications with especial emphasis on cancer investigations. TrAC Trends in Analytical Chemistry 152, pages 116604.
Crossref
Wei Zhang, Ling Wang, Dan Li, Douglas H. Campbell, Bradley J. Walsh, Nicolle H. Packer, Qing Dong, Erkang Wang & Yuling Wang. (2022) Phenotypic profiling of pancreatic ductal adenocarcinoma plasma-derived small extracellular vesicles for cancer diagnosis and cancer stage prediction: a proof-of-concept study. Analytical Methods 14:23, pages 2255-2265.
Crossref
Charles P. Hinzman, Baldev Singh, Shivani Bansal, Yaoxiang Li, Anton Iliuk, Michael Girgis, Kelly M. Herremans, Jose G. Trevino, Vijay K. Singh, Partha P. Banerjee & Amrita K. Cheema. (2022) A multi‐omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells. Journal of Extracellular Vesicles 11:6.
Crossref
Raquel Vaz, Verónica M. Serrano, Yuselis Castaño-Guerrero, Ana R. Cardoso, Manuela F. Frasco & M. Goreti F. Sales. (2022) Breaking the classics: Next-generation biosensors for the isolation, profiling and detection of extracellular vesicles. Biosensors and Bioelectronics: X 10, pages 100115.
Crossref
Susanne Dechantsreiter, Ashley R. Ambrose, Jonathan D. Worboys, Joey M. E. Lim, Sylvia Liu, Rajesh Shah, M. Angeles Montero, Anne Marie Quinn, Tracy Hussell, Gillian M. Tannahill & Daniel M. Davis. (2022) Heterogeneity in extracellular vesicle secretion by single human macrophages revealed by super‐resolution microscopy. Journal of Extracellular Vesicles 11:4.
Crossref
Ryan P. McNamara, Yijun Zhou, Anthony B. Eason, Justin T. Landis, Meredith G. Chambers, Smaranda Willcox, Tiffany A. Peterson, Blake Schouest, Nicholas J. Maness, Andrew G. MacLean, Lindsey M. Costantini, Jack D. Griffith & Dirk Peter Dittmer. (2022) Imaging of surface microdomains on individual extracellular vesicles in 3‐D. Journal of Extracellular Vesicles 11:3.
Crossref
Xuehui Liu, Zhiyou Zong, Xinzhuo Liu, Qiang Li, Ang Li, Chen Xu & Dingbin Liu. (2021) Stimuli‐Mediated Specific Isolation of Exosomes from Blood Plasma for High‐Throughput Profiling of Cancer Biomarkers. Small Methods 6:2.
Crossref
Elisa Pesce, Nicola Manfrini, Chiara Cordiglieri, Spartaco Santi, Alessandra Bandera, Andrea Gobbini, Paola Gruarin, Andrea Favalli, Mauro Bombaci, Alessandro Cuomo, Federica Collino, Giulia Cricrì, Riccardo Ungaro, Andrea Lombardi, Davide Mangioni, Antonio Muscatello, Stefano Aliberti, Francesco Blasi, Andrea Gori, Sergio Abrignani, Raffaele De Francesco, Stefano Biffo & Renata Grifantini. (2022) Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response. Frontiers in Immunology 12.
Crossref
Sarah Owen, Emily Prantzalos, Valerie Gunchick, Vaibhav Sahai & Sunitha Nagrath. (2022) Synergistic Analysis of Circulating Tumor Cells Reveals Prognostic Signatures in Pilot Study of Treatment-Naïve Metastatic Pancreatic Cancer Patients. Biomedicines 10:1, pages 146.
Crossref
Yoon-Jin Lee, Chul Won Seo, Donghyeong Lee & Dongsic Choi. (2022) Proteomics of Extracellular Vesicle in Glioblastoma. Brain Tumor Research and Treatment 10:4, pages 207.
Crossref
Joshua A. Welsh, Bryce Killingsworth, Julia Kepley, Tim Traynor, Sean Cook, Jason Savage, Jenn Marte, Min-Jung Lee, Hoyoung M. Maeng, Michelle L. Pleet, Setty Magana, André Gorgens, Cecile L. Maire, Katrin Lamszus, Franz L. Ricklefs, Maria J. Merino, W. Marston Linehan, Tim Greten, Tomer Cooks, Curtis C. Harris, Andrea Apolo, Asim Abdel-Mageed, Alexander R. Ivanov, Jane B. Trepel, Matthew Roth, Mercedes Tkach, Aleksandar Milosavljevic, Clotilde Théry, Amy LeBlanc, Jay A. Berzofsky, Eytan Ruppin, Kenneth Aldape, Kevin Camphausen, James L. Gulley, Ionita Ghiran, Steve Jacobson & Jennifer C. Jones. (2022) MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays. Cell Reports Methods 2:1, pages 100136.
Crossref
Diogo Fortunato, Danilo Mladenović, Mattia Criscuoli, Francesca Loria, Kadi-Liis Veiman, Davide Zocco, Kairi Koort & Natasa Zarovni. (2021) Opportunities and Pitfalls of Fluorescent Labeling Methodologies for Extracellular Vesicle Profiling on High-Resolution Single-Particle Platforms. International Journal of Molecular Sciences 22:19, pages 10510.
Crossref
Mareike Waldenmaier, Tanja Seibold, Thomas Seufferlein & Tim Eiseler. (2021) Pancreatic Cancer Small Extracellular Vesicles (Exosomes): A Tale of Short- and Long-Distance Communication. Cancers 13:19, pages 4844.
Crossref
Surya Shrivastava, Roslyn M. Ray, Leo Holguin, Lilliana Echavarria, Nicole Grepo, Tristan A. Scott, John Burnett & Kevin V. Morris. (2021) Exosome-mediated stable epigenetic repression of HIV-1. Nature Communications 12:1.
Crossref
Zubair Ahmed Nizamudeen, Rachael Xerri, Christopher Parmenter, Kiran Suain, Robert Markus, Lisa Chakrabarti & Virginie Sottile. (2021) Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties. Cells 10:9, pages 2413.
Crossref
Ki Woo Kim. (2021) In situ and ex situ imaging of plant extracellular vesicles as nanovectors for cross‐domain communication . Journal of Phytopathology 169:9, pages 515-524.
Crossref
Yue Du, Chenze Wang, Chen Zhang, Lingyun Guo, Yanzhu Chen, Meng Yan, Qianghui Feng, Mingtao Shang, Weibing Kuang, Zhengxia Wang & Zhen-Li Huang. (2021) Computational framework for generating large panoramic super-resolution images from localization microscopy. Biomedical Optics Express 12:8, pages 4759.
Crossref
Sara Cavallaro, Petra Hååg, Kristina Viktorsson, Anatol Krozer, Kristina Fogel, Rolf Lewensohn, Jan Linnros & Apurba Dev. (2021) Comparison and optimization of nanoscale extracellular vesicle imaging by scanning electron microscopy for accurate size-based profiling and morphological analysis. Nanoscale Advances 3:11, pages 3053-3063.
Crossref
Federico Colombo, Erienne G. Norton & Emanuele Cocucci. (2021) Microscopy approaches to study extracellular vesicles. Biochimica et Biophysica Acta (BBA) - General Subjects 1865:4, pages 129752.
Crossref
Joshua A. Welsh, Bryce Killingsworth, Julia Kepley, Tim Traynor, Kathy McKinnon, Jason Savage, Deven Appel, Kenneth Aldape, Kevin Camphausen, Jay A. Berzofsky, Alexander R. Ivanov, Ionita H. Ghiran & Jennifer C. Jones. (2021) A simple, high-throughput method of protein and label removal from extracellular vesicle samples. Nanoscale 13:6, pages 3737-3745.
Crossref
Bart de Jong, Eric Raul Barros, Joost G. J. Hoenderop & Juan Pablo Rigalli. (2020) Recent Advances in Extracellular Vesicles as Drug Delivery Systems and Their Potential in Precision Medicine. Pharmaceutics 12:11, pages 1006.
Crossref
Hongqiang Ma & Yang Liu. (2020) Super-resolution localization microscopy: Toward high throughput, high quality, and low cost. APL Photonics 5:6.
Crossref
Lenka Lorencova, Tomas Bertok, Aniko Bertokova, Veronika Gajdosova, Stefania Hroncekova, Alica Vikartovska, Peter Kasak & Jan Tkac. (2020) Exosomes as a Source of Cancer Biomarkers: Advances in Electrochemical Biosensing of Exosomes. ChemElectroChem 7:9, pages 1956-1973.
Crossref
Su Wang, Adeel Khan, Rongrong Huang, Shiyi Ye, Kaili Di, Tao Xiong & Zhiyang Li. (2020) Recent advances in single extracellular vesicle detection methods. Biosensors and Bioelectronics 154, pages 112056.
Crossref
Fabiao Yu, Yanlong Xing, Ting Wang & Ziyi Cheng. (2022) Analysis of Single Extracellular Vesicles for Biomedical Applications with Especial Emphasis on Cancer Investigations. SSRN Electronic Journal.
Crossref