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Critical Reviews in Clinical Laboratory Sciences Volume 38, 2001 - Issue 3
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Research Article

Folic Acid

James G. Donnelly The Division of Biochemistry, Department of Pathology, the Ottawa Hospital and the University of Ottawa, Ottawa, Ontario, Canada
Pages 183-223 | Published online: 29 Sep 2008

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Omid Asbaghi, Damoon Ashtary-Larky, Reza Bagheri, Behzad Nazarian, Hadi Pourmirzaei Olyaei, Mahnaz Rezaei Kelishadi, Michael Nordvall, Alexei Wong, Frédéric Dutheil & Amirmansour Alavi Naeini. (2022) Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials. Critical Reviews in Food Science and Nutrition 62:30, pages 8435-8453.
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Dezhao Kong, Liqiang Liu, Shanshan Song, Hua Kuang & Chuanlai Xu. (2016) Development of ic-ELISA and lateral-flow immunochromatographic assay strip for the detection of folic acid in energy drinks and milk samples. Food and Agricultural Immunology 27:6, pages 841-854.
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Shin Young Kim, Jung Wook Lim, Jin Woo Kim, So Yeon Park & Ju Tae Seo. (2015) Association between genetic polymorphisms in folate-related enzyme genes and infertile men with non-obstructive azoospermia. Systems Biology in Reproductive Medicine 61:5, pages 286-292.
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Marie-Laure Frelut, Jean-Pierre Nicolas, Jean-Claude Guilland & Genevieve Potier de Courcy. (2011) Methylenetetrahydrofolate reductase 677 C->T polymorphism: A link between birth weight and insulin resistance in obese adolescents. International Journal of Pediatric Obesity 6:sup3, pages e312-317.
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Articles from other publishers (66)

Irfan, Neha Soleja & Mohd Mohsin. (2023) FRET-based probe for ratiometric detection and imaging of folic acid in real-time. Analytical Biochemistry 679, pages 115285.
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Henry H. L. Wu, Thomas McDonnell & Rajkumar Chinnadurai. (2023) Physiological Associations between Vitamin B Deficiency and Diabetic Kidney Disease. Biomedicines 11:4, pages 1153.
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Hatim Boughanem, Pallavi Kompella, Francisco J Tinahones & Manuel Macias-Gonzalez. (2023) An overview of vitamins as epidrugs for colorectal cancer prevention. Nutrition Reviews 81:4, pages 455-479.
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Sarah Louise Killeen, Niamh Donnellan, Sharleen L. O'Reilly, Mark A. Hanson, Mary L. Rosser, Virna P. Medina, Chandni Maria Jacob, Hema Divakar, Moshe Hod, Liona C. Poon, Lina Bergman, Patrick O'Brien, Anil Kapur, Bo Jacobsson, Cynthia V. Maxwell, Harold David McIntyre, Lesley Regan, Esraa Algurjia, Ronald C. Ma, Sumaiya Adam & Fionnuala M. McAuliffe. (2023) Using FIGO Nutrition Checklist counselling in pregnancy: A review to support healthcare professionals . International Journal of Gynecology & Obstetrics 160:S1, pages 10-21.
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Srijan Mukherjee, Subhrajyoti Ghosh & Shyam Biswas. (2022) A MOF chemosensor for highly sensitive and ultrafast detection of folic acid in biofriendly medium, paper strips and real samples. Inorganic Chemistry Frontiers 9:23, pages 6288-6298.
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Manman Liu, Qingqing Chen, Yalian Sun, Lingzhou Zeng, Hongchen Wu, Qing Gu & Ping Li. (2022) Probiotic Potential of a Folate-Producing Strain Latilactobacillus sakei LZ217 and Its Modulation Effects on Human Gut Microbiota. Foods 11:2, pages 234.
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Omid Zahed, Kianoush Khosravi-Darani, Amir Mohammad Mortazavian & Abdorreza Mohammadi. (2022) Effects of cultivation conditions on biofortification of yogurt with natural folate by Propionibacterium freudenreichii. Biocatalysis and Agricultural Biotechnology 39, pages 102267.
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F. Olmo, A. Rodriguez, A. Colina & A. Heras. (2021) UV/Vis absorption spectroelectrochemistry of folic acid. Journal of Solid State Electrochemistry 26:1, pages 29-37.
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Fereshteh Ansari & Hadi Pourjafar. 2022. Retention of Bioactives in Food Processing. Retention of Bioactives in Food Processing 277 308 .
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Jingbo Fu, Yang Liu, Chen Wang, Hongxia Zhang, Bin Yu, Ye Wang & Haiying Zhu. (2021) Persistent follicular granulosa cell senescence and apoptosis induced by methotrexate leading to oocyte dysfunction and aberrant embryo development. Clinical and Translational Science 14:5, pages 2043-2054.
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Yongquan Wang, Bing Yan, Alireza Abbaspourrad & Yongqiang Cheng. (2021) Improved photostability of folic acid by the radical-scavenging effect of tannic acid. LWT 142, pages 111050.
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Igor Petrone, Paula Sabbo Bernardo, Everton Cruz dos Santos & Eliana Abdelhay. (2021) MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review. Genes 12:4, pages 587.
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Iwona Gęca & Mieczyslaw Korolczuk. (2019) Sensitive Determination of Folic Acid using a Solid Bismuth Microelectrode by Adsorptive Stripping Voltammetry. Electroanalysis 32:3, pages 496-502.
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Mateusz Ochab, Iwona Gęca & Mieczyslaw Korolczuk. (2019) Sensitive Simultaneous Determination of Rutin and Folic Acid with the Use of a Solid Lead Electrode by Means of Adsorptive Stripping Voltammetry. Electroanalysis 31:11, pages 2206-2213.
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Mihaela Baibarac, Ion Smaranda, Andreea Nila & Constantin Serbschi. (2019) Optical properties of folic acid in phosphate buffer solutions: the influence of pH and UV irradiation on the UV-VIS absorption spectra and photoluminescence. Scientific Reports 9:1.
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Antonio Quotadamo, Pasquale Linciano, Maria Paola Costi & Alberto Venturelli. (2019) Optimization of N ‐alkylation in the Synthesis of Methotrexate and Pteridine‐based Derivatives Under Microwave‐Irradiation . ChemistrySelect 4:15, pages 4429-4433.
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Abeer Mahmoud & Mohamed Ali. (2019) Methyl Donor Micronutrients that Modify DNA Methylation and Cancer Outcome. Nutrients 11:3, pages 608.
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Marcelo de Sousa, Luis Augusto Visani de Luna, Leandro Carneiro Fonseca, Selma Giorgio & Oswaldo Luiz Alves. (2018) Folic-Acid-Functionalized Graphene Oxide Nanocarrier: Synthetic Approaches, Characterization, Drug Delivery Study, and Antitumor Screening. ACS Applied Nano Materials 1:2, pages 922-932.
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M Irfan, M Ismail, M Azhar Beg, A Shabbir, A Rashid Kayani & G Kaukab Raja. (2016) Association of the MTHFR C677T (rs1801133) polymorphism with idiopathic male infertility in a local Pakistani population . Balkan Journal of Medical Genetics 19:1, pages 51-62.
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Kazunori Kadota, Kumi Semba, Ryosuke Shakudo, Hideyuki Sato, Yuto Deki, Yoshiyuki Shirakawa & Yuichi Tozuka. (2016) Inhibition of Photodegradation of Highly Dispersed Folic Acid Nanoparticles by the Antioxidant Effect of Transglycosylated Rutin. Journal of Agricultural and Food Chemistry 64:15, pages 3062-3069.
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Ahmad Settin, Rizk El-Baz, Azza Ismaeel, Wafaa Tolba & Wafaa A Allah. (2014) Association of ACE and MTHFR genetic polymorphisms with type 2 diabetes mellitus: Susceptibility and complications . Journal of the Renin-Angiotensin-Aldosterone System 16:4, pages 838-843.
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Hadi Mahmoudi Moghaddam, Hadi Beitollahi, Somayeh Tajik & Hossein Soltani. (2015) Fabrication of a Nanostructure Based Electrochemical Sensor for Voltammetric Determination of Epinephrine, Uric Acid and Folic Acid. Electroanalysis 27:11, pages 2620-2628.
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Luís M. C. Ferreira, Paulo R. Martins, Koiti Araki, Henrique H. Toma & Lúcio Angnes. (2015) Amperometric Folic Acid Quantification Using a Supramolecular Tetraruthenated Nickel Porphyrin µ-Peroxo-Bridged Matrix Modified Electrode Associated to Batch Injection Analysis. Electroanalysis 27:10, pages 2322-2328.
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N.M. Jadavji, L. Deng, O. Malysheva, M.A. Caudill & R. Rozen. (2015) MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring. Neuroscience 300, pages 1-9.
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Ini-Isabée Witzel, Herbert F. Jelinek, Kinda Khalaf, Sungmun Lee, Ahsan H. Khandoker & Habiba Alsafar. (2015) Identifying Common Genetic Risk Factors of Diabetic Neuropathies. Frontiers in Endocrinology 6.
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Mancheng Gong, Wenjing Dong, Tingyu He, Zhirong Shi, Guiying Huang, Rui Ren, Sichong Huang, Shaopeng Qiu & Runqiang Yuan. (2015) MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta-Analysis Involving 26 Studies. PLOS ONE 10:3, pages e0121147.
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D. Montjean, A. Zini, C. Ravel, S. Belloc, A. Dalleac, H. Copin, P. Boyer, K. McElreavey & M. Benkhalifa. (2015) Sperm global DNA methylation level: association with semen parameters and genome integrity. Andrology 3:2, pages 235-240.
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B. Toprak, H. Z. Yalcın & A. Colak. (2014) Vitamin B12 and folate deficiency: should we use a different cutoff value for hematologic disorders?. International Journal of Laboratory Hematology 36:4, pages 409-414.
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Yukinori Tamura, Ayumi Inoue, Yoshinobu Ijiri, Aki Naemura & Junichiro Yamamoto. (2014) Short- and long-term treatment with folic acid suppresses thrombus formation in atherogenic mice in vivo. Pathophysiology 21:2, pages 169-175.
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Rizk El-Baz, Ahmad Settin, Azza Ismaeel, Abd Allah Khaleel, Tarek Abbas, Wafaa Tolba, Wafaa Abd Allah & Mohammed Abd El-Kader Sobh. (2012) MTHFR C677T, A1298C and ACE I/D polymorphisms as risk factors for diabetic nephropathy among type 2 diabetic patients. Journal of the Renin-Angiotensin-Aldosterone System 13:4, pages 472-477.
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Zhao Kun, Zhao Ling, He Yi, Cai Ying, Tian Dongmei, Zang Shuliang & Zhang Yuyang. (2012) Electrochemical behavior of folic acid in neutral solution on the modified glassy carbon electrode: Platinum nanoparticles doped multi-walled carbon nanotubes with Nafion as adhesive. Journal of Electroanalytical Chemistry 677-680, pages 105-112.
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Michel M. Araújo, Eric Marchioni, Martine Bergaentzle, Minjie Zhao, Florent Kuntz, Emeline Hahn & Anna Lucia C. H. Villavicencio. (2011) Irradiation Stability of Folic Acid in Powder and Aqueous Solution. Journal of Agricultural and Food Chemistry 59:4, pages 1244-1248.
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