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Virulence Volume 8, 2017 - Issue 7
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Research paper

Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against Klebsiella pneumoniae ST258

Valéria SzijártóArsanis Biosciences GmbH, Vienna, AustriaCorrespondence[email protected] [email protected]
,
Luis M. GuachallaArsanis Biosciences GmbH, Vienna, Austria
,
Katharina HartlArsanis Biosciences GmbH, Vienna, Austria
,
Cecília VargaArsanis Biosciences GmbH, Vienna, Austria
,
Adriana BadarauArsanis Biosciences GmbH, Vienna, Austria
,
Irina MirkinaArsanis Biosciences GmbH, Vienna, Austria
,
Zehra C. VisramArsanis Biosciences GmbH, Vienna, Austria
,
Lukas StulikArsanis Biosciences GmbH, Vienna, Austria
,
Christine A. PowerArsanis Biosciences GmbH, Vienna, Austria
,
Eszter NagyArsanis Biosciences GmbH, Vienna, Austria
&
Gábor NagyArsanis Biosciences GmbH, Vienna, AustriaCorrespondence[email protected] [email protected]
 show all
Pages 1203-1215 | Received 08 Sep 2016, Accepted 03 Jan 2017, Published online: 14 Feb 2017

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Sophia K. Berry, Steven Rust, Carolina Caceres, Lorraine Irving, Josefin Bartholdson Scott, David E. Tabor, Gordon Dougan, Graham Christie, Paul Warrener, Ralph Minter & Andrew J. Grant. (2022) Phenotypic whole-cell screening identifies a protective carbohydrate epitope on Klebsiella pneumoniae. mAbs 14:1.
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Rachelle Babb & Liise-anne Pirofski. (2017) Help is on the way: Monoclonal antibody therapy for multi-drug resistant bacteria. Virulence 8:7, pages 1055-1058.
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Mirella Luciani & Luigi Iannetti. (2017) Monoclonal antibodies and bacterial virulence. Virulence 8:6, pages 635-636.
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Articles from other publishers (29)

Paeton L. Wantuch & David A. Rosen. (2023) Klebsiella pneumoniae: adaptive immune landscapes and vaccine horizons. Trends in Immunology.
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Ahlam N. QerqezRui P. Silva & Jennifer A. Maynard. (2023) Outsmarting Pathogens with Antibody Engineering. Annual Review of Chemical and Biomolecular Engineering 14:1, pages 217-241.
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Chirag K. Kumar, Kirsty Sands, Timothy R. Walsh, Seamus O’Brien, Mike Sharland, Joseph A. Lewnard, Hao Hu, Padmini Srikantiah & Ramanan Laxminarayan. (2023) Global, regional, and national estimates of the impact of a maternal Klebsiella pneumoniae vaccine: A Bayesian modeling analysis. PLOS Medicine 20:5, pages e1004239.
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Tiago Barcelos Valiatti, Rodrigo Cayô, Fernanda Fernandes Santos, Francisco Ozório Bessa-Neto, Ramon Giovani Brandão Silva, Ruanita Veiga, Márcia de Nazaré Miranda Bahia, Lívia Maria Guimarães Dutra Guerra, Antônio Carlos Campos Pignatari, Cintya de Oliveira Souza, Danielle Murici Brasiliense & Ana Cristina Gales. (2022) Genomic Analysis of Klebsiella pneumoniae ST258 Strain Coproducing KPC-2 and CTX-M-14 Isolated from Poultry in the Brazilian Amazon Region. Antibiotics 11:12, pages 1835.
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Daria Artyszuk, Radosław Izdebski, Anna Maciejewska, Marta Kaszowska, Aleksandra Herud, Valeria Szijártó, Marek Gniadkowski & Jolanta Lukasiewicz. (2020) The Impact of Insertion Sequences on O-Serotype Phenotype and Its O-Locus-Based Prediction in Klebsiella pneumoniae O2 and O1. International Journal of Molecular Sciences 21:18, pages 6572.
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M. Courtney Safir, Sujata M. Bhavnani, Christine M. Slover, Paul G. Ambrose & Christopher M. Rubino. (2020) Antibacterial Drug Development: A New Approach Is Needed for the Field to Survive and Thrive. Antibiotics 9:7, pages 412.
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Antonio J. Martín-Galiano & Michael J. McConnell. (2019) Using Omics Technologies and Systems Biology to Identify Epitope Targets for the Development of Monoclonal Antibodies Against Antibiotic-Resistant Bacteria. Frontiers in Immunology 10.
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L. Ponoop Prasad Patro & Thenmalarchelvi Rathinavelan. (2019) Targeting the Sugary Armor of Klebsiella Species. Frontiers in Cellular and Infection Microbiology 9.
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Steven D. Kelly, Bradley R. Clarke, Olga G. Ovchinnikova, Ryan P. Sweeney, Monica L. Williamson, Todd L. Lowary & Chris Whitfield. (2019) Klebsiella pneumoniae O1 and O2ac antigens provide prototypes for an unusual strategy for polysaccharide antigen diversification. Journal of Biological Chemistry 294:28, pages 10863-10876.
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Petrosillo, Taglietti & Granata. (2019) Treatment Options for Colistin Resistant Klebsiella pneumoniae: Present and Future. Journal of Clinical Medicine 8:7, pages 934.
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Michael P. Motley, Kasturi Banerjee & Bettina C. Fries. (2019) Monoclonal antibody-based therapies for bacterial infections. Current Opinion in Infectious Diseases 32:3, pages 210-216.
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Michael J. McConnell. (2019) Where are we with monoclonal antibodies for multidrug-resistant infections?. Drug Discovery Today 24:5, pages 1132-1138.
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Michele Mutti, Katharina Ramoni, Gábor Nagy, Eszter Nagy & Valéria Szijártó. (2018) A New Tool for Complement Research: In vitro Reconstituted Human Classical Complement Pathway. Frontiers in Immunology 9.
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Roberto Adamo & Immaculada Margarit. (2018) Fighting Antibiotic-Resistant Klebsiella pneumoniae with “Sweet” Immune Targets. mBio 9:3.
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Jiwon Lee & George Georgiou. (2018) High-affinity IgA against microbial glycans. Nature Immunology 19:6, pages 514-515.
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Tim Rollenske, Valeria Szijarto, Jolanta Lukasiewicz, Luis M. Guachalla, Katarina Stojkovic, Katharina Hartl, Lukas Stulik, Simone Kocher, Felix Lasitschka, Mohammed Al-Saeedi, Jutta Schröder-Braunstein, Moritz von Frankenberg, Gereon Gaebelein, Peter Hoffmann, Sabrina Klein, Klaus Heeg, Eszter Nagy, Gabor Nagy & Hedda Wardemann. (2018) Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen. Nature Immunology 19:6, pages 617-624.
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Elizabeth Diago-Navarro, Michael P. Motley, Gonzalo Ruiz-Peréz, Winnie Yu, Julianne Austin, Bruna M. S. Seco, Guozhi Xiao, Aniska Chikhalya, Peter H. Seeberger & Bettina C. Fries. (2018) Novel, Broadly Reactive Anticapsular Antibodies against Carbapenem-Resistant Klebsiella pneumoniae Protect from Infection. mBio 9:2.
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Bradley R. Clarke, Olga G. Ovchinnikova, Steven D. Kelly, Monica L. Williamson, Jennifer E. Butler, Bin Liu, Lu Wang, Xi Gou, Rainer Follador, Todd L. Lowary & Chris Whitfield. (2018) Molecular basis for the structural diversity in serogroup O2-antigen polysaccharides in Klebsiella pneumoniae. Journal of Biological Chemistry 293:13, pages 4666-4679.
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Meghan E. Pennini, Anna De Marco, Mark Pelletier, Jessica Bonnell, Romana Cvitkovic, Martina Beltramello, Elisabetta Cameroni, Siro Bianchi, Fabrizia Zatta, Wei Zhao, Xiaodong Xiao, Maria M. Camara, Antonio DiGiandomenico, Elena Semenova, Antonio Lanzavecchia, Paul Warrener, JoAnn Suzich, Qun Wang, Davide Corti & C. Kendall Stover. (2017) Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae. Nature Communications 8:1.
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Luis M. Guachalla, Katharina Hartl, Cecília Varga, Lukas Stulik, Irina Mirkina, Stefan Malafa, Eszter Nagy, Gábor Nagy & Valéria Szijártó. (2017) Multiple Modes of Action of a Monoclonal Antibody against Multidrug-Resistant Escherichia coli Sequence Type 131- H 30 . Antimicrobial Agents and Chemotherapy 61:11.
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Luis M. Guachalla, Katarina Stojkovic, Katharina Hartl, Marta Kaszowska, Yadhu Kumar, Benjamin Wahl, Tobias Paprotka, Eszter Nagy, Jolanta Lukasiewicz, Gábor Nagy & Valéria Szijártó. (2017) Discovery of monoclonal antibodies cross-reactive to novel subserotypes of K. pneumoniae O3. Scientific Reports 7:1.
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Eszter Nagy, Gábor Nagy, Christine A. Power, Adriana Badarau & Valéria Szijártó. 2017. Recombinant Antibodies for Infectious Diseases. Recombinant Antibodies for Infectious Diseases 119 153 .

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