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Virulence Volume 11, 2020 - Issue 1
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Research Paper

Identification of FDA-approved antivirulence drugs targeting the Pseudomonas aeruginosa quorum sensing effector protein PqsE

Valerio Baldellia Department of Science, University Roma Tre, Rome, ItalyView further author information
,
Francesca D’Angeloa Department of Science, University Roma Tre, Rome, ItalyORCID Iconhttps://orcid.org/0000-0001-5880-1087View further author information
ORCID Icon,
Viola Pavoncelloa Department of Science, University Roma Tre, Rome, ItalyORCID Iconhttps://orcid.org/0000-0003-0110-9094View further author information
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Ersilia Vita Fiscarellib Laboratory of Cystic Fibrosis Microbiology, Bambino Gesú Hospital, Rome, ItalyView further author information
,
Paolo Viscaa Department of Science, University Roma Tre, Rome, ItalyView further author information
,
Giordano Rampionia Department of Science, University Roma Tre, Rome, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1735-8565View further author information
ORCID Icon &
Livia Leonia Department of Science, University Roma Tre, Rome, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2046-4297View further author information
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Pages 652-668 | Received 30 Jan 2020, Accepted 05 May 2020, Published online: 28 May 2020

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Xiaolong Shao, Yingpeng Xie, Yingchao Zhang, Jingui Liu, Yiqing Ding, Min Wu, Xin Wang & Xin Deng. (2020) Novel therapeutic strategies for treating Pseudomonas aeruginosa infection. Expert Opinion on Drug Discovery 15:12, pages 1403-1423.
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Matteo Calcagnile, Inès Jeguirim, Salvatore Maurizio Tredici, Fabrizio Damiano & Pietro Alifano. (2023) Spiramycin Disarms Pseudomonas aeruginosa without Inhibiting Growth. Antibiotics 12:3, pages 499.
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Qiaoqiang Li, Shen Mao, Hong Wang & Xinyi Ye. (2022) The Molecular Architecture of Pseudomonas aeruginosa Quorum-Sensing Inhibitors. Marine Drugs 20:8, pages 488.
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Morgana Letizia, Marta Mellini, Alessandra Fortuna, Paolo Visca, Francesco Imperi, Livia Leoni & Giordano Rampioni. (2022) PqsE Expands and Differentially Modulates the RhlR Quorum Sensing Regulon in Pseudomonas aeruginosa. Microbiology Spectrum 10:3.
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Kayla A. Simanek & Jon E. Paczkowski. (2022) Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance. Microorganisms 10:6, pages 1247.
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Ronit Vogt Sionov & Doron Steinberg. (2022) Targeting the Holy Triangle of Quorum Sensing, Biofilm Formation, and Antibiotic Resistance in Pathogenic Bacteria. Microorganisms 10:6, pages 1239.
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Pengfei She, Yaqian Liu, Lanlan Xu, Yimin Li, Zehao Li, Shasha Liu, Zubair Hussain & Yong Wu. (2022) SPR741, Double- or Triple-Combined With Erythromycin and Clarithromycin, Combats Drug-Resistant Klebsiella pneumoniae, Its Biofilms, and Persister Cells. Frontiers in Cellular and Infection Microbiology 12.
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Janne G. Thöming & Susanne Häussler. 2022. Pseudomonas aeruginosa. Pseudomonas aeruginosa 303 323 .
Aishwarya Vetrivel, Monica Ramasamy, Preethi Vetrivel, Santhi Natchimuthu, Shobana Arunachalam, Gon-Sup Kim & Rajeswari Murugesan. (2021) Pseudomonas aeruginosa Biofilm Formation and Its Control. Biologics 1:3, pages 312-336.
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Vuong Van Hung Le & Jasna Rakonjac. (2021) Nitrofurans: Revival of an “old” drug class in the fight against antibiotic resistance. PLOS Pathogens 17:7, pages e1009663.
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Isabelle R. Taylor, Jon E. Paczkowski, Philip D. Jeffrey, Brad R. Henke, Chari D. Smith & Bonnie L. Bassler. (2021) Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production . ACS Chemical Biology 16:4, pages 740-752.
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Gloria Soberón‐Chávez, Abigail González‐Valdez, Martín P. Soto‐Aceves & Miguel Cocotl‐Yañez. (2020) Rhamnolipids produced by Pseudomonas : from molecular genetics to the market . Microbial Biotechnology 14:1, pages 136-146.
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María Claudia Peña-González, Naybi Muñoz-Cázares & Luis Manuel Peña-Rodríguez. (2021) Natural Inhibitors of Quorum-Sensing Factors: a Novel Strategy to Control Pathogenic Bacteria. Revista Brasileira de Farmacognosia 30:6, pages 743-755.
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