Citations (38)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Carmen L. Pessuti, Quintus G. Medley, Ning Li, Chia-Ling Huang, Joseph Loureiro, Angela Banks, Qin Zhang, Deise F. Costa, Kleber S. Ribeiro, Heloisa Nascimento, Cristina Muccioli, Alessandra G. Commodaro, Qian Huang & Rubens Belfort$suffix/text()$suffix/text(). (2023) Differential Proteins Expression Distinguished Between Patients With Infectious and Noninfectious Uveitis. Ocular Immunology and Inflammation 0:0, pages 1-8.
Read now
Read now
Yuping Guo, Yaning Feng, Peiwen Fan, Xuan Yao, Yanchun Peng, Ruozheng Wang & Gulina Kuerban. (2022) Expression and Clinical Significance of KLRG1 and 2B4 on T Cells in the Peripheral Blood and Tumour of Patients with Cervical Cancer. Immunological Investigations 51:3, pages 670-687.
Read now
Read now
GuangLin Song, YanLing Lu, LiNa Tang, Min Li, Jie Yin, HongMing Chen & JunDa Ling. (2021) (−)-4-O-(4-O-β-D-glucopyranosylcaffeoyl) quinic acid enhanced the efficacy of anti-PD-L1 against esophageal carcinoma through inhibiting PI3K pathway. Immunopharmacology and Immunotoxicology 43:6, pages 806-812.
Read now
Read now
Ornella Franzese, Belinda Palermo, Cosmo Di Donna, Isabella Sperduti, Virginia Ferraresi, Helena Stabile, Angela Gismondi, Angela Santoni & Paola Nisticò. (2016) Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. OncoImmunology 5:5.
Read now
Read now
Articles from other publishers (34)
Renzo Perales-Linares, Nektaria Maria Leli, Hesham Mohei, Silvia Beghi, Osvaldo D. Rivera, Nektarios Kostopoulos, Andrea Giglio, Subin S. George, Mireia Uribe-Herranz, Francesca Costabile, Stefano Pierini, Sergei Pustylnikov, Giorgos Skoufos, Yoseph Barash, Artemis G. Hatzigeorgiou, Constantinos Koumenis, Amit Maity, Michael T. Lotze & Andrea Facciabene. (2023) Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance. Cancer Research 83:21, pages 3562-3576.
Crossref
Crossref
Vardges Tserunyan & Stacey D. Finley. (2023) A systems and computational biology perspective on advancing CAR therapy. Seminars in Cancer Biology 94, pages 34-49.
Crossref
Crossref
Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman & Alan P. Kumar. (2023) PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer. Molecular Cancer 22:1.
Crossref
Crossref
Sylvain Ladoire, Cédric Rébé & François Ghiringhelli. (2023) Associating Immunotherapy and Targeted Therapies: Facts and Hopes. Clinical Cancer Research 29:7, pages 1183-1193.
Crossref
Crossref
Yutong Liu, Adam S. Sperling, Eric L. Smith & David J. Mooney. (2023) Optimizing the manufacturing and antitumour response of CAR T therapy. Nature Reviews Bioengineering 1:4, pages 271-285.
Crossref
Crossref
Yibin Zhang, Tianying Chang, Qi Lu, Yingzi Cui, Dongmei Zhang, Baitong Wang, Peng Xu, Jing Lu, Jinhui Ma, Zhiguo Lv & Jian Wang. (2022) Exploring the Potential Mechanism of Qi-Shen-Di-Huang Drug Formulary for Myasthenia Gravis (MG) based on UHPLC-QE-MS Network Pharmacology and Molecular Docking Techniques. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-16.
Crossref
Crossref
Frances Seymour, Jonathan Carmichael, Claire Taylor, Christopher Parrish & Gordon Cook. (2022) Immune senescence in multiple myeloma—a role for mitochondrial dysfunction?. Leukemia 36:10, pages 2368-2373.
Crossref
Crossref
Mireia Guerau-de-Arellano, Zayda L. Piedra-Quintero & Philip N. Tsichlis. (2022) Akt isoforms in the immune system. Frontiers in Immunology 13.
Crossref
Crossref
Jamie I. Scott, Lorena Mendive-Tapia, Doireann Gordon, Nicole D. Barth, Emily J. Thompson, Zhiming Cheng, David Taggart, Takanori Kitamura, Alberto Bravo-Blas, Edward W. Roberts, Jordi Juarez-Jimenez, Julien Michel, Berber Piet, I. Jolanda de Vries, Martijn Verdoes, John Dawson, Neil O. Carragher, Richard A. O’ Connor, Ahsan R. Akram, Margaret Frame, Alan Serrels & Marc Vendrell. (2022) A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies. Nature Communications 13:1.
Crossref
Crossref
Peter Rose, Natasja K. van den Engel, Julia R. Kovács, Rudolf A. Hatz, Louis Boon & Hauke Winter. (2022) Anti-Gr-1 Antibody Provides Short-Term Depletion of MDSC in Lymphodepleted Mice with Active-Specific Melanoma Therapy. Vaccines 10:4, pages 560.
Crossref
Crossref
Pankaj Gaur, Mikayel Mkrtichyan, Vivek Verma, Nazli Jafarzadeh, Mariana Hattar, Seema Gupta & Samir N. Khleif. 2022. PI3K and AKT Isoforms in Immunity. PI3K and AKT Isoforms in Immunity
217
234
.
Zayd Ahmad & Payaningal R. Somanath. 2022. PI3K and AKT Isoforms in Immunity. PI3K and AKT Isoforms in Immunity
349
366
.
Rasha Abu-Eid & Frank James Ward. (2021) Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients. Immunology Letters 240, pages 1-8.
Crossref
Crossref
Kirit Singh, Kelly M. Hotchkiss, Kisha K. Patel, Daniel S. Wilkinson, Aditya A. Mohan, Sarah L. Cook & John H. Sampson. (2021) Enhancing T Cell Chemotaxis and Infiltration in Glioblastoma. Cancers 13:21, pages 5367.
Crossref
Crossref
Bart Vanhaesebroeck, Matthew W. D. Perry, Jennifer R. Brown, Fabrice André & Klaus Okkenhaug. (2021) PI3K inhibitors are finally coming of age. Nature Reviews Drug Discovery 20:10, pages 741-769.
Crossref
Crossref
Matteo Caforio, Emmanuel de Billy, Biagio De Angelis, Stefano Iacovelli, Concetta Quintarelli, Valeria Paganelli & Valentina Folgiero. (2021) PI3K/Akt Pathway: The Indestructible Role of a Vintage Target as a Support to the Most Recent Immunotherapeutic Approaches. Cancers 13:16, pages 4040.
Crossref
Crossref
Leena Abdullah, L. Benjamin Hills, Evan B. Winter & Yina H. Huang. (2021) Diverse Roles of Akt in T cells. Immunometabolism 3:1, pages e210007.
Crossref
Crossref
Charlotte M. Mousset, Willemijn Hobo, Aafke de Ligt, Sjoerd Baardman, Nicolaas P. M. Schaap, Joop H. Jansen, Anniek B. van der Waart & Harry Dolstra. (2020) Cell composition and expansion strategy can reduce the beneficial effect of AKT-inhibition on functionality of CD8+ T cells. Cancer Immunology, Immunotherapy 69:11, pages 2259-2273.
Crossref
Crossref
Benling Xu, Long Yuan, Guangyu Chen, Tiepeng Li, Jinxue Zhou, Chengjuan Zhang, Peng Qin, Musleh M. Muthana, Shengdian Wang, Xuexiang Du & Quanli Gao. (2019) S-15 in combination of Akt inhibitor promotes the expansion of CD45RA−CCR7+ tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1+Tim-3+ cells as well as regulatory T cells. Cancer Cell International 19:1.
Crossref
Crossref
Vivek Verma, Rajeev K Shrimali, Shamim Ahmad, Winjie Dai, Hua Wang, Sumin Lu, Rahul Nandre, Pankaj Gaur, Jose Lopez, Moshe Sade-Feldman, Keren Yizhak, Stacey L. Bjorgaard, Keith T. Flaherty, Jennifer A. Wargo, Genevieve M. Boland, Ryan J. Sullivan, Gad Getz, Scott A. Hammond, Ming Tan, Jingjing Qi, Phillip Wong, Taha Merghoub, Jedd Wolchok, Nir Hacohen, John E. Janik, Mikayel Mkrtichyan, Seema Gupta & Samir N. Khleif. (2019) PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance. Nature Immunology 20:9, pages 1231-1243.
Crossref
Crossref
Leila Amini, Tino Vollmer, Desiree J. Wendering, Anke Jurisch, Sybille Landwehr-Kenzel, Natalie Maureen Otto, Karsten Jürchott, Hans-Dieter Volk, Petra Reinke & Michael Schmueck-Henneresse. (2019) Comprehensive Characterization of a Next-Generation Antiviral T-Cell Product and Feasibility for Application in Immunosuppressed Transplant Patients. Frontiers in Immunology 10.
Crossref
Crossref
Larissa S. Carnevalli, Charles Sinclair, Molly A. Taylor, Pablo Morentin Gutierrez, Sophie Langdon, Anna M. L. Coenen-Stass, Lorraine Mooney, Adina Hughes, Laura Jarvis, Anna Staniszewska, Claire Crafter, Ben Sidders, Elizabeth Hardaker, Kevin Hudson & Simon T. Barry. (2018) PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity. Journal for ImmunoTherapy of Cancer 6:1.
Crossref
Crossref
Shogo Nabe, Takeshi Yamada, Junpei Suzuki, Koji Toriyama, Toshiaki Yasuoka, Makoto Kuwahara, Atsushi Shiraishi, Katsuto Takenaka, Masaki Yasukawa & Masakatsu Yamashita. (2018)
Reinforce the antitumor activity of
CD
8
+
T cells via glutamine restriction
. Cancer Science 109:12, pages 3737-3750.
Crossref
Crossref
Maryam Honardoost & Seyed Mohammad Ali Hosseini Rad. (2017) Triangle of AKT2, miRNA, and Tumorigenesis in Different Cancers. Applied Biochemistry and Biotechnology 185:2, pages 524-540.
Crossref
Crossref
Sally S. M. Lee-Sayer, Nina Maeshima, Meghan N. Dougan, Anita Dahiya, Arif A. Arif, Manisha Dosanjh, Christopher A. Maxwell & Pauline Johnson. (2018) Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells. European Journal of Immunology 48:5, pages 803-814.
Crossref
Crossref
Hee Jin Lee, Young-Ae Kim, Chan Kyu Sim, Sun-Hee Heo, In Hye Song, Hye Seon Park, Suk Young Park, Won Seon Bang, In Ah Park, Miseon Lee, Jung Hoon Lee, Yeon Sook Cho, Suhwan Chang, Jaeyun Jung, Jisun Kim, Sae Byul Lee, Sung Youl Kim, Myeong Sup Lee & Gyungyub Gong. (2017) Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer. Oncotarget 8:69, pages 113345-113359.
Crossref
Crossref
Christopher A. Klebanoff, Joseph G. Crompton, Anthony J. Leonardi, Tori N. Yamamoto, Smita S. Chandran, Robert L. Eil, Madhusudhanan Sukumar, Suman K. Vodnala, Jinhui Hu, Yun Ji, David Clever, Mary A. Black, Devikala Gurusamy, Michael J. Kruhlak, Ping Jin, David F. Stroncek, Luca Gattinoni, Steven A. Feldman & Nicholas P. Restifo. (2017) Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy. JCI Insight 2:23.
Crossref
Crossref
Rajeev K. Shrimali, Shamim Ahmad, Vivek Verma, Peng Zeng, Sudha Ananth, Pankaj Gaur, Rachel M. Gittelman, Erik Yusko, Catherine Sanders, Harlan Robins, Scott A. Hammond, John E. Janik, Mikayel Mkrtichyan, Seema Gupta & Samir N. Khleif. (2017) Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis. Cancer Immunology Research 5:9, pages 755-766.
Crossref
Crossref
Rasha Abu Eid, Shamim Ahmad, Yuan Lin, Mason Webb, Zuzana Berrong, Rajeev Shrimali, Takumi Kumai, Sudha Ananth, Paulo C. Rodriguez, Esteban Celis, John Janik, Mikayel Mkrtichyan & Samir N. Khleif. (2017)
Enhanced Therapeutic Efficacy and Memory of Tumor-Specific CD8 T Cells by
Ex Vivo
PI3K-δ Inhibition
. Cancer Research 77:15, pages 4135-4145.
Crossref
Crossref
Kinga Majchrzak, Michelle H. Nelson, Jacob S. Bowers, Stefanie R. Bailey, Megan M. Wyatt, John M. Wrangle, Mark P. Rubinstein, Juan C. Varela, Zihai Li, Richard A. Himes, Sherine S.L. Chan & Chrystal M. Paulos. (2017) ?-catenin and PI3K? inhibition expands precursor Th17 cells with heightened stemness and antitumor activity. JCI Insight 2:8.
Crossref
Crossref
Klaus Okkenhaug, Mariona Graupera & Bart Vanhaesebroeck. (2016) Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy. Cancer Discovery 6:10, pages 1090-1105.
Crossref
Crossref
Rasha Abu Eid, Ghazaleh Shoja E. Razavi, Mikayel Mkrtichyan, John Janik & Samir N. Khleif. (2016) Old-School Chemotherapy in Immunotherapeutic Combination in Cancer, A Low-cost Drug Repurposed. Cancer Immunology Research 4:5, pages 377-382.
Crossref
Crossref
Stephanie Zdanov, Magis Mandapathil, Rasha Abu Eid, Saudat Adamson-Fadeyi, Willie Wilson, Jiahua Qian, Andrea Carnie, Nadya Tarasova, Mikayel Mkrtichyan, Jay A. Berzofsky, Theresa L. Whiteside & Samir N. Khleif. (2016) Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells. Cancer Immunology Research 4:4, pages 354-365.
Crossref
Crossref
Michelle Yap, Sophie Brouard, Claire Pecqueur & Nicolas Degauque. (2015) Targeting CD8 T-Cell Metabolism in Transplantation. Frontiers in Immunology 6.
Crossref
Crossref