OncoImmunology, Volume 4, Issue 5 (2015)

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OncoImmunology, Volume 4, Issue 5 (2015)

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Original Research

Highly clonal regulatory T-cell population in follicular lymphoma – inverse correlation with the diversity of CD8+ T cells
Xiao Liu, Girish Venkataraman, Jiaying Lin, Kazuma Kiyotani, Sonali Smith, Magdeline Montoya, Yusuke Nakamura & Justin Kline
Article: e1002728
Published online: 21 May 2015
AbstractforHighly clonal regulatory T-cell population in follicular lymphoma – inverse correlation with the diversity of CD8+ T cells | Full Text | References | PDF (1.4 MB) | Supplemental
  • 1856 Views
  • 23 CrossRef citations
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Open Access
PDL1 expression is an independent prognostic factor in localized GIST
François Bertucci, Pascal Finetti, Emilie Mamessier, Maria Abbondanza Pantaleo, Annalisa Astolfi, Jerzy Ostrowski & Daniel Birnbaum
Article: e1002729
Published online: 21 May 2015
AbstractforPDL1 expression is an independent prognostic factor in localized GIST | Full Text | References | PDF (231.1 KB) | Supplemental
  • 2342 Views
  • 59 CrossRef citations
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Author's View

Article
The mutually regulatory loop of epithelial–mesenchymal transition and immunosuppression in cancer progression
Limo Chen, John V Heymach, F Xiao-Feng Qin & Don L Gibbons
Article: e1002731
Published online: 21 May 2015
AbstractforThe mutually regulatory loop of epithelial–mesenchymal transition and immunosuppression in cancer progression | Full Text | References | PDF (175.4 KB)
  • 921 Views
  • 21 CrossRef citations
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Free Access
Article
Chronic inflammation in endometriosis and endometriosis-associated ovarian cancer: New roles for the “old” complement pathway
Robert P Edwards, Xin Huang & Anda M Vlad
Article: e1002732
Published online: 21 May 2015
AbstractforChronic inflammation in endometriosis and endometriosis-associated ovarian cancer: New roles for the “old” complement pathway | Full Text | References | PDF (169.1 KB)
  • 1149 Views
  • 24 CrossRef citations
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Original Research

TCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance
Florent Guerville, Sophie Daburon, Romain Marlin, Lydia Lartigue, Severine Loizon, Vincent Pitard, Lionel Couzi, Jean-François Moreau, Julie Déchanet-Merville & Benjamin Faustin
Article: e1003011
Published online: 21 May 2015
AbstractforTCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance | Full Text | References | PDF (818.6 KB)
  • 1472 Views
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Author's View

Article
Expression profile of the human IDO1 protein, a cancer drug target involved in tumoral immune resistance
Nathalie Vigneron, Nicolas van Baren & Benoît J Van den Eynde
Article: e1003012
Published online: 21 May 2015
AbstractforExpression profile of the human IDO1 protein, a cancer drug target involved in tumoral immune resistance | Full Text | References | PDF (362.2 KB)
  • 2153 Views
  • 19 CrossRef citations
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Open Access
Article
Shaping the tumor microenvironment with Modified Vaccinia Virus Ankara and TLR9 ligand
Xavier Préville, Karola Rittner & Laetitia Fend
Article: e1003013
Published online: 21 May 2015
AbstractforShaping the tumor microenvironment with Modified Vaccinia Virus Ankara and TLR9 ligand | Full Text | References | PDF (183.8 KB)
  • 570 Views
  • 1 CrossRef citations
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Open Access
Article
CD39: A complementary target to immune checkpoints to counteract tumor-mediated immunosuppression
Nathalie Bonnefoy, Jérémy Bastid, Gilles Alberici, Armand Bensussan & Jean-François Eliaou
Article: e1003015
Published online: 21 May 2015
AbstractforCD39: A complementary target to immune checkpoints to counteract tumor-mediated immunosuppression | Full Text | References | PDF (56.4 KB)
  • 1486 Views
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Free Access
Article
Time to Akt
Superior tumor-reactive T cells for adoptive immunotherapy
Anniek B van der Waart, Willemijn Hobo & Harry Dolstra
Article: e1003016
Published online: 21 May 2015
AbstractforTime to Akt | Full Text | References | PDF (140.3 KB)
  • 988 Views
  • 2 CrossRef citations
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Original Research

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8+ T-cell proliferation and survival
Rasha Abu Eid, Kevin M Friedman, Mikayel Mkrtichyan, Andrea Walens, William King, John Janik & Samir N Khleif
Article: e1005448
Published online: 21 May 2015
AbstractforAkt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8+ T-cell proliferation and survival | Full Text | References | PDF (1.1 MB) | Supplemental
  • 2456 Views
  • 38 CrossRef citations
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Open Access
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival
Giulia Di Lullo, Magda Marcatti, Silvia Heltai, Emanuela Brunetto, Cristina Tresoldi, Attilio Bondanza, Chiara Bonini, Maurilio Ponzoni, Giovanni Tonon, Fabio Ciceri, Claudio Bordignon & Maria Pia Protti
Article: e1005460
Published online: 21 May 2015
AbstractforTh22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival | Full Text | References | PDF (1 MB) | Supplemental
  • 2291 Views
  • 34 CrossRef citations
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Open Access
Antitumor immunization of mothers delays tumor development in cancer-prone offspring
Giuseppina Barutello, Claudia Curcio, Michela Spadaro, Maddalena Arigoni, Rosalinda Trovato, Elisabetta Bolli, Yujuan Zheng, Francesco Ria, Elena Quaglino, Manuela Iezzi, Federica Riccardo, Lars Holmgren, Guido Forni & Federica Cavallo
Article: e1005500
Published online: 21 May 2015
AbstractforAntitumor immunization of mothers delays tumor development in cancer-prone offspring | Full Text | References | PDF (454.3 KB)
  • 990 Views
  • 11 CrossRef citations
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Author's View

Article
Restoration of defective cross-presentation in tumors by gemcitabine
Alison M McDonnell, W Joost Lesterhuis, Andrea Khong, Anna K Nowak, Richard A Lake, Andrew J Currie & Bruce WS Robinson
Article: e1005501
Published online: 21 May 2015
AbstractforRestoration of defective cross-presentation in tumors by gemcitabine | Full Text | References | PDF (130.9 KB)
  • 782 Views
  • 13 CrossRef citations
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Open Access
Article
Intratumoral delivery of mRNA: Overcoming obstacles for effective immunotherapy
Kevin Van der Jeught, Sandra Van Lint, Kris Thielemans & Karine Breckpot
Article: e1005504
Published online: 21 May 2015
AbstractforIntratumoral delivery of mRNA: Overcoming obstacles for effective immunotherapy | Full Text | References | PDF (113 KB)
  • 1108 Views
  • 9 CrossRef citations
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Free Access
Article
HLA class I as a predictor of clinical prognosis and CTL infiltration as a predictor of chemosensitivity in ovarian cancer
Yoshihiko Hirohashi, Toshihiko Torigoe, Tasuku Mariya, Vitaly Kochin, Tsuyoshi Saito & Noriyuki Sato
Article: e1005507
Published online: 21 May 2015
AbstractforHLA class I as a predictor of clinical prognosis and CTL infiltration as a predictor of chemosensitivity in ovarian cancer | Full Text | References | PDF (141.4 KB)
  • 717 Views
  • 10 CrossRef citations
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Free Access
Article
B cells drive Th2 responses by instructing human dendritic cell maturation
Mohan S Maddur & Jagadeesh Bayry
Article: e1005508
Published online: 21 May 2015
AbstractforB cells drive Th2 responses by instructing human dendritic cell maturation | Full Text | References | PDF (155.7 KB)
  • 895 Views
  • 12 CrossRef citations
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Free Access
Article
Deciphering the genetic evolution of T-cell resistance in melanoma
Antje Sucker & Annette Paschen
Article: e1005510
Published online: 21 May 2015
AbstractforDeciphering the genetic evolution of T-cell resistance in melanoma | Full Text | References | PDF (135.8 KB)
  • 767 Views
  • 3 CrossRef citations
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Free Access
Article
Personalized peptide vaccination for advanced colorectal cancer
Tetsuro Sasada, Shiro Kibe, Yoshito Akagi & Kyogo Itoh
Article: e1005512
Published online: 21 May 2015
AbstractforPersonalized peptide vaccination for advanced colorectal cancer | Full Text | References | PDF (166.6 KB)
  • 833 Views
  • 7 CrossRef citations
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Open Access

Review

Trial Watch: Therapeutic vaccines in metastatic renal cell carcinoma
Pierre Combe, Eleonore de Guillebon, Constance Thibault, Clémence Granier, Eric Tartour & Stéphane Oudard
Article: e1001236
Published online: 21 May 2015
AbstractforTrial Watch: Therapeutic vaccines in metastatic renal cell carcinoma | Full Text | References | PDF (154.4 KB)
  • 3689 Views
  • 20 CrossRef citations
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Free Access

Original Research

Rapid generation of NY-ESO-1-specific CD4+ THELPER1 cells for adoptive T-cell therapy
Simone Kayser, Cristina Boβ, Judith Feucht, Kai-Erik Witte, Alexander Scheu, Hans-Jörg Bülow, Stefanie Joachim, Stefan Stevanović, Michael Schumm, Susanne M Rittig, Peter Lang, Martin Röcken, Rupert Handgretinger & Tobias Feuchtinger
Article: e1002723
Published online: 21 May 2015
AbstractforRapid generation of NY-ESO-1-specific CD4+ THELPER1 cells for adoptive T-cell therapy | Full Text | References | PDF (698 KB) | Supplemental
  • 1616 Views
  • 17 CrossRef citations
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Free Access

Review

Article
Trial watch: Naked and vectored DNA-based anticancer vaccines
Norma Bloy, Aitziber Buqué, Fernando Aranda, Francesca Castoldi, Alexander Eggermont, Isabelle Cremer, Catherine Sautès-Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
Article: e1026531
Published online: 21 May 2015
AbstractforTrial watch: Naked and vectored DNA-based anticancer vaccines | Full Text | References | PDF (169.4 KB)
  • 2879 Views
  • 24 CrossRef citations
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Author's View

Article
New role for antigen-presenting activated pDCs in promoting Th17 cells and impacting antitumor immunity
Leslie Guéry & Stéphanie Hugues
Article: e_988476
Published online: 21 May 2015
AbstractforNew role for antigen-presenting activated pDCs in promoting Th17 cells and impacting antitumor immunity | Full Text | References | PDF (230.3 KB)
  • 927 Views
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Open Access

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