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OncoImmunology Volume 4, 2015 - Issue 8
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Original Research

The nitric oxide radical scavenger carboxy-PTIO reduces the immunosuppressive activity of myeloid-derived suppressor cells and potentiates the antitumor activity of adoptive cytotoxic T lymphocyte immunotherapy

Kosuke HiranoDepartment of Immunotherapeutics; The University of Tokyo Hospital; Tokyo, Japan;Department of Gastrointestinal Surgery; The University of Tokyo Hospital; Tokyo, Japan
,
Akihiro HosoiDepartment of Immunotherapeutics; The University of Tokyo Hospital; Tokyo, Japan;Medinet Co. Ltd.; Kanagawa, Japan
,
Hirokazu MatsushitaDepartment of Immunotherapeutics; The University of Tokyo Hospital; Tokyo, Japan
,
Tamaki IinoDepartment of Immunotherapeutics; The University of Tokyo Hospital; Tokyo, Japan;Medinet Co. Ltd.; Kanagawa, Japan
,
Satoshi UehaDepartment of Molecular Preventive Medicine; Graduate School of Medicine; The University of Tokyo; Tokyo, Japan
,
Kouji MatsushimaDepartment of Molecular Preventive Medicine; Graduate School of Medicine; The University of Tokyo; Tokyo, Japan
,
Yasuyuki SetoDepartment of Gastrointestinal Surgery; The University of Tokyo Hospital; Tokyo, Japan
&
Kazuhiro KakimiDepartment of Immunotherapeutics; The University of Tokyo Hospital; Tokyo, JapanCorrespondence[email protected]
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Article: e1019195 | Received 13 Jan 2015, Accepted 09 Feb 2015, Published online: 30 Jun 2015

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Koji Nagaoka, Akihiro Hosoi, Tamaki Iino, Yasuyuki Morishita, Hirokazu Matsushita & Kazuhiro Kakimi. (2018) Dendritic cell vaccine induces antigen-specific CD8+ T cells that are metabolically distinct from those of peptide vaccine and is well-combined with PD-1 checkpoint blockade. OncoImmunology 7:3.
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