OncoImmunology, Volume 4, Issue 8 (2015)

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OncoImmunology, Volume 4, Issue 8 (2015)

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Author's View

Opinion
Tumor cell-derived microparticles: a new form of cancer vaccine
Huafeng Zhang & Bo Huang
Article: e1017704
Published online: 30 Jun 2015
AbstractforTumor cell-derived microparticles: a new form of cancer vaccine | Full Text | References | PDF (142.5 KB)
  • 1403 Views
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Opinion
A clinical trial of multiple peptides vaccination for advanced head and neck cancer patients induced immune responses and prolonged OS
Yoshihiro Yoshitake, Yasuharu Nishimura, Yusuke Nakamura & Masanori Shinohara
Article: e1022307
Published online: 30 Jun 2015
AbstractforA clinical trial of multiple peptides vaccination for advanced head and neck cancer patients induced immune responses and prolonged OS | Full Text | References | PDF (409.8 KB)
  • 565 Views
  • 5 CrossRef citations
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Opinion
Fbxw7 suppresses cancer metastasis by inhibiting niche formation
Kanae Yumimoto & Keiichi I Nakayama
Article: e1022308
Published online: 30 Jun 2015
AbstractforFbxw7 suppresses cancer metastasis by inhibiting niche formation | Full Text | References | PDF (237 KB)
  • 813 Views
  • 9 CrossRef citations
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Opinion
Long-lasting antitumor effects provided by radiotherapy combined with the immunocytokine L19-IL2
Nicolle H Rekers, Catharina ML Zegers, Wilfred TV Germeraad, Ludwig Dubois & Philippe Lambin
Article: e1021541
Published online: 30 Jun 2015
AbstractforLong-lasting antitumor effects provided by radiotherapy combined with the immunocytokine L19-IL2 | Full Text | References | PDF (155.4 KB)
  • 919 Views
  • 16 CrossRef citations
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Open Access
Opinion
TLR5 signaling, commensal microbiota and systemic tumor promoting inflammation: the three parcae of malignant progression
Melanie R Rutkowski & Jose R Conejo-Garcia
Article: e1021542
Published online: 30 Jun 2015
AbstractforTLR5 signaling, commensal microbiota and systemic tumor promoting inflammation: the three parcae of malignant progression | Full Text | References | PDF (299.9 KB)
  • 679 Views
  • 7 CrossRef citations
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Opinion
HHLA2 and TMIGD2: new immunotherapeutic targets of the B7 and CD28 families
Murali Janakiram, Jordan M Chinai, Aimin Zhao, Joseph A Sparano & Xingxing Zang
Article: e1026534
Published online: 30 Jun 2015
AbstractforHHLA2 and TMIGD2: new immunotherapeutic targets of the B7 and CD28 families | Full Text | References | PDF (162.9 KB)
  • 2591 Views
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Opinion
miR-155 releases the brakes on antitumor T cells
Yun Ji & Luca Gattinoni
Article: e1026533
Published online: 30 Jun 2015
AbstractformiR-155 releases the brakes on antitumor T cells | Full Text | References | PDF (270.2 KB)
  • 803 Views
  • 4 CrossRef citations
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Opinion
Autocrine signaling of type 1 interferons in successful anticancer chemotherapy
Erika Vacchelli, Antonella Sistigu, Takahiro Yamazaki, Ilio Vitale, Laurence Zitvogel & Guido Kroemer
Article: e988042
Published online: 25 Jul 2015
AbstractforAutocrine signaling of type 1 interferons in successful anticancer chemotherapy | Full Text | References | PDF (211.7 KB)
  • 824 Views
  • 3 CrossRef citations
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Opinion
Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses
Anna Vilgelm & Ann Richmond
Article: e1009299
Published online: 25 Jul 2015
AbstractforCombined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses | Full Text | References | PDF (224.4 KB)
  • 568 Views
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Review

Review
Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy
Heleen H Van Acker, Sébastien Anguille, Viggo F Van Tendeloo & Eva Lion
Article: e1021538
Published online: 25 Jun 2015
AbstractforEmpowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy | Full Text | References | PDF (227.5 KB)
  • 3469 Views
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Open Access

MIATA Compliant Research Paper

Article
Survivin-targeted immunotherapy drives robust polyfunctional T cell generation and differentiation in advanced ovarian cancer patients
Neil L Berinstein, Mohan Karkada, Amit M Oza, Kunle Odunsi, Jeannine A Villella, John J Nemunaitis, Michael A Morse, Tanja Pejovic, James Bentley, Marc Buyse, Rita Nigam, Genevieve M Weir, Lisa D MacDonald, Tara Quinton, Rajkannan Rajagopalan, Kendall Sharp, Andrea Penwell, Leeladhar Sammatur, Tomasz Burzykowski, Marianne M Stanford & Marc Mansour
Article: e1026529
Published online: 29 Jun 2015
AbstractforSurvivin-targeted immunotherapy drives robust polyfunctional T cell generation and differentiation in advanced ovarian cancer patients | Full Text | References | PDF (534.2 KB) | Supplemental
  • 3259 Views
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Open Access

Original Research

Article
Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients
Kalijn F Bol, Carl G Figdor, Erik HJG Aarntzen, Marieke EB Welzen, Michelle M van Rossum, Willeke AM Blokx, Mandy WMM van de Rakt, Nicole M Scharenborg, Annemiek J de Boer, Jeanette M Pots, Michel AM olde Nordkamp, Tom GM van Oorschot, Roel DM Mus, Sandra AJ Croockewit, Joannes FM Jacobs, Gerold Schuler, Bart Neyns, Jonathan M Austyn, Cornelis JA Punt, Gerty Schreibelt & I Jolanda M de Vries
Article: e1019197
Published online: 25 Jun 2015
AbstractforIntranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients | Full Text | References | PDF (363.6 KB) | Supplemental
  • 2452 Views
  • 52 CrossRef citations
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Open Access
Article
The nitric oxide radical scavenger carboxy-PTIO reduces the immunosuppressive activity of myeloid-derived suppressor cells and potentiates the antitumor activity of adoptive cytotoxic T lymphocyte immunotherapy
Kosuke Hirano, Akihiro Hosoi, Hirokazu Matsushita, Tamaki Iino, Satoshi Ueha, Kouji Matsushima, Yasuyuki Seto & Kazuhiro Kakimi
Article: e1019195
Published online: 30 Jun 2015
AbstractforThe nitric oxide radical scavenger carboxy-PTIO reduces the immunosuppressive activity of myeloid-derived suppressor cells and potentiates the antitumor activity of adoptive cytotoxic T lymphocyte immunotherapy | Full Text | References | PDF (1.1 MB)
  • 1433 Views
  • 19 CrossRef citations
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Article
Depletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells
Kyle A Wilson, Stephen R Goding, Harold R Neely, Kristina M Harris & Paul Andrew Antony
Article: e1019196
Published online: 30 Jun 2015
AbstractforDepletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells | Full Text | References | PDF (725.4 KB) | Supplemental
  • 1719 Views
  • 9 CrossRef citations
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Open Access
Article
Cross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103− and XCR1+CD103+ dendritic cells
Ben Wylie, Elke Seppanen, Kun Xiao, Rachael Zemek, Damien Zanker, Sandro Prato, Bree Foley, Prue H Hart, Richard A Kroczek, Weisan Chen & Jason Waithman
Article: e1019198
Published online: 13 Jul 2015
AbstractforCross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103− and XCR1+CD103+ dendritic cells | Full Text | References | PDF (747.4 KB)
  • 1976 Views
  • 27 CrossRef citations
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Article
Identification of characteristic TRB V usage in HBV-associated HCC by using differential expression profiling analysis
Yingxin Han, Xing Liu, Yuqi Wang, Xiaolei Wu, Yanfang Guan, Hongmei Li, Xinchun Chen, Boping Zhou, Qing Yuan, Ying Ou, Renhua Wu, Wanqiu Huang, Yun Wang, Ming Zhang, Yinxin Zhang, Dongxing Zhu, Hongmei Zhu, Ling Yang, Xin Yi, Chen Huang & Jian Huang
Article: e1021537
Published online: 30 Jun 2015
AbstractforIdentification of characteristic TRB V usage in HBV-associated HCC by using differential expression profiling analysis | Full Text | References | PDF (892.8 KB) | Supplemental
  • 1990 Views
  • 30 CrossRef citations
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Article
Intratumoral oncolytic adenoviral treatment modulates the glioma microenvironment and facilitates systemic tumor-antigen-specific T cell therapy
Jian Qiao, Mahua Dey, Alan L Chang, Julius W Kim, Jason Miska, Alex Ling, Dirk M Nettlebeck, Yu Han, Lingjiao Zhang & Maciej S Lesniak
Article: e1022302
Published online: 30 Jun 2015
AbstractforIntratumoral oncolytic adenoviral treatment modulates the glioma microenvironment and facilitates systemic tumor-antigen-specific T cell therapy | Full Text | References | PDF (750.5 KB)
  • 1199 Views
  • 21 CrossRef citations
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Article
Antitumor activity of epigenetic immunomodulation combined with CTLA-4 blockade in syngeneic mouse models
A Covre, S Coral, H Nicolay, G Parisi, C Fazio, F Colizzi, E Fratta, A M Di Giacomo, L Sigalotti, P G Natali & M Maio
Article: e1019978
Published online: 30 Jun 2015
AbstractforAntitumor activity of epigenetic immunomodulation combined with CTLA-4 blockade in syngeneic mouse models | Full Text | References | PDF (583.5 KB)
  • 1378 Views
  • 52 CrossRef citations
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Article
Lectin-like transcript 1 is a marker of germinal center-derived B-cell non-Hodgkin's lymphomas dampening natural killer cell functions
Claire Germain, Thierry Guillaudeux, Elisabeth D Galsgaard, Catherine Hervouet, Nedra Tekaya, Anne-Sophie Gallouet, Julien Fassy, Franck Bihl, Gwenola Poupon, Anne Lazzari, Pieter Spee, Fabienne Anjuère, Céline Pangault, Karin Tarte, Patrick Tas, Luc Xerri & Veronique M Braud
Article: e1026503
Published online: 30 Jun 2015
AbstractforLectin-like transcript 1 is a marker of germinal center-derived B-cell non-Hodgkin's lymphomas dampening natural killer cell functions | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1412 Views
  • 28 CrossRef citations
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Article
Several immune escape patterns in non-Hodgkin's lymphomas
Camille Laurent, Konstantina Charmpi, Pauline Gravelle, Marie Tosolini, Camille Franchet, Loïc Ysebaert, Pierre Brousset, Alexandre Bidaut, Bernard Ycart & Jean-Jacques Fournié
Article: e1026530
Published online: 25 Jul 2015
AbstractforSeveral immune escape patterns in non-Hodgkin's lymphomas | Full Text | References | PDF (1.9 MB)
  • 3265 Views
  • 72 CrossRef citations
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Open Access
Article
Evidence of Th2 polarization of the sentinel lymph node (SLN) in melanoma
Travis E Grotz, James W Jakub, Aaron S Mansfield, Rachel Goldenstein, Elizabeth Ann L Enninga, Wendy K Nevala, Alexey A Leontovich & Svetomir N Markovic
Article: e1026504
Published online: 30 Jun 2015
AbstractforEvidence of Th2 polarization of the sentinel lymph node (SLN) in melanoma | Full Text | References | PDF (552.8 KB)
  • 1350 Views
  • 24 CrossRef citations
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Open Access
Article
Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression
Wendy WJ Unger, Christian T Mayer, Steef Engels, Christina Hesse, Maurizio Perdicchio, Franz Puttur, Ingeborg Streng-Ouwehand, Manja Litjens, Hakan Kalay, Luciana Berod, Tim Sparwasser & Yvette van Kooyk
Article: e970462
Published online: 30 Jun 2015
AbstractforAntigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression | Full Text | References | PDF (583.1 KB)
  • 1651 Views
  • 28 CrossRef citations
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Open Access
Article
Phenotypic analysis of T cells infiltrating colon cancers: Correlations with oncogenetic status
Mircea Chirica, Lionel Le Bourhis, Jacqueline Lehmann-Che, Victor Chardiny, Fatiha Bouhidel, Laure Foulboeuf, Jean Marc Gornet, Nelson Lourenco, Nicolas Dulphy, Antoine Toubert & Matthieu Allez
Article: e1016698
Published online: 15 Jul 2015
AbstractforPhenotypic analysis of T cells infiltrating colon cancers: Correlations with oncogenetic status | Full Text | References | PDF (1.3 MB) | Supplemental
  • 718 Views
  • 11 CrossRef citations
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Article
BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties
Cara L Haymaker, Richard C Wu, Krit Ritthipichai, Chantale Bernatchez, Marie-Andrée Forget, Jie Qing Chen, Hui Liu, Ena Wang, Francesco Marincola, Patrick Hwu & Laszlo G Radvanyi
Article: e1014246
Published online: 25 Jul 2015
AbstractforBTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties | Full Text | References | PDF (1.1 MB) | Supplemental
  • 3026 Views
  • 39 CrossRef citations
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Open Access
Article
Anti-proliferative and pro-apoptotic activity of GD2 ganglioside-specific monoclonal antibody 3F8 in human melanoma cells
Chun-Yen Tsao, Francesco Sabbatino, Nai-Kong V Cheung, Jeff Chi-feng Hsu, Vincenzo Villani, Xinhui Wang & Soldano Ferrone
Article: e1023975
Published online: 25 Jul 2015
AbstractforAnti-proliferative and pro-apoptotic activity of GD2 ganglioside-specific monoclonal antibody 3F8 in human melanoma cells | Full Text | References | PDF (678.2 KB) | Supplemental
  • 1116 Views
  • 23 CrossRef citations
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