Advanced search
Publication Cover
OncoImmunology Volume 5, 2016 - Issue 2
Submit an article Journal homepage
1,792
Views
33
CrossRef citations to date
0
Altmetric
Original Research

Drug-induced hyperploidy stimulates an antitumor NK cell response mediated by NKG2D and DNAM-1 receptors

Andrea Acebes-HuertaDepartamento de Biología Funcional, Inmunología, IUOPA, Universidad de Oviedo, Oviedo, Spain
,
Seila Lorenzo-HerreroDepartamento de Biología Funcional, Inmunología, IUOPA, Universidad de Oviedo, Oviedo, Spain
,
Alicia R. FolguerasDepartamento de Bioquímica y Biología Molecular, IUOPA, Universidad de Oviedo, Oviedo, Spain
,
Leticia Huergo-ZapicoDepartamento de Biología Funcional, Inmunología, IUOPA, Universidad de Oviedo, Oviedo, Spain
,
Carlos Lopez-LarreaDepartamento de Biología Funcional, Inmunología, IUOPA, Universidad de Oviedo, Oviedo, Spain;Departamento de Inmunología, Hospital Universitario Central de Asturias, Oviedo, Spain;Fundación Renal Iñigo Álvarez de Toledo, Madrid, Spain
,
Alejandro López-SotoDepartamento de Biología Funcional, Inmunología, IUOPA, Universidad de Oviedo, Oviedo, Spain;Departamento de Inmunología, Hospital Universitario Central de Asturias, Oviedo, SpainCorrespondence[email protected] [email protected]
&
Segundo GonzalezDepartamento de Biología Funcional, Inmunología, IUOPA, Universidad de Oviedo, Oviedo, SpainCorrespondence[email protected] [email protected]
 show all
Article: e1074378 | Received 14 Jul 2015, Accepted 15 Jul 2015, Published online: 26 Feb 2016

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Fernando Aranda, Kariman Chaba, Norma Bloy, Pauline Garcia, Chloé Bordenave, Isabelle Martins, Gautier Stoll, Antoine Tesniere, Guido Kroemer & Laura Senovilla. (2018) Immune effectors responsible for the elimination of hyperploid cancer cells. OncoImmunology 7:8.
Read now
Claire Vanpouille-Box, Claire Lhuillier, Lucillia Bezu, Fernando Aranda, Takahiro Yamazaki, Oliver Kepp, Jitka Fucikova, Radek Spisek, Sandra Demaria, Silvia C. Formenti, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2017) Trial watch: Immune checkpoint blockers for cancer therapy. OncoImmunology 6:11.
Read now
Alejandro López-Soto, Segundo Gonzalez & Lorenzo Galluzzi. (2017) Soluble NKG2D ligands limit the efficacy of immune checkpoint blockade. OncoImmunology 6:10.
Read now
Ji Sung Kim, Bo Ram Shin, Hong Kyung Lee, Jae Hee Lee, Ki Hun Kim, Jeong Eun Choi, A Young Ji, Jin Tae Hong, Youngsoo Kim & Sang-Bae Han. (2017) Cd226 natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis in vivo. OncoImmunology 6:8.
Read now

Articles from other publishers (29)

Reena Gupta, Mustafa M. Kadhim, Abduladheem Turki Jalil, Mohammed Qasim Alasheqi, Fahad Alsaikhan, Nurkhan Khalimovna Mukhamedova, Andrés Alexis Ramírez-Coronel, Zanko Hassan Jawhar, Pushpamala Ramaiah & Masoud Najafi. (2023) The interactions of docetaxel with tumor microenvironment. International Immunopharmacology 119, pages 110214.
Crossref
Christian Sordo-Bahamonde, Seila Lorenzo-Herrero, Ana P. Gonzalez-Rodriguez, Alejandra Martínez-Pérez, Juan P. Rodrigo, Juana M. García-Pedrero & Segundo Gonzalez. (2023) Chemo-Immunotherapy: A New Trend in Cancer Treatment. Cancers 15:11, pages 2912.
Crossref
Mohammad Hossein Kazemi, Mahdieh Shokrollahi Barough, Zahra Momeni-Varposhti, Alireza Ghanavatinejad, Ali Zarehzadeh Mehrabadi, Behnam Sadeghi & Reza Falak. (2023) Pentoxifylline changes the balance of immune cell population in breast tumor-infiltrating lymphocytes. Medical Oncology 40:6.
Crossref
Amber B. Jones, Abbey Rocco, Lawrence S. Lamb, Gregory K. Friedman & Anita B. Hjelmeland. (2022) Regulation of NKG2D Stress Ligands and Its Relevance in Cancer Progression. Cancers 14:9, pages 2339.
Crossref
You Nie, Dandan Liu, Wen Yang, Yazhuo Li, Lihua Zhang, Xia Cheng, Ruyu Chen, Bingbing Yuan, Guangzheng Zhang & Hongwei Wang. (2022) Increased expression of TIGIT and KLRG1 correlates with impaired CD56bright NK cell immunity in HPV16-related cervical intraepithelial neoplasia. Virology Journal 19:1.
Crossref
Yanwei Song, Yucui Zhao, Zheng Deng, Ruyi Zhao & Qian Huang. (2021) Stress-Induced Polyploid Giant Cancer Cells: Unique Way of Formation and Non-Negligible Characteristics. Frontiers in Oncology 11.
Crossref
Congying PuSiyao TaoJun XuMin Huang. (2021) Harnessing Genomic Stress for Antitumor Immunity. Antioxidants & Redox Signaling 34:14, pages 1128-1150.
Crossref
Elisa C. Toffoli, Abdolkarim Sheikhi, Yannick D. Höppner, Pita de Kok, Mahsa Yazdanpanah-Samani, Jan Spanholtz, Henk M. W. Verheul, Hans J. van der Vliet & Tanja D. de Gruijl. (2021) Natural Killer Cells and Anti-Cancer Therapies: Reciprocal Effects on Immune Function and Therapeutic Response. Cancers 13:4, pages 711.
Crossref
Yuqing Cao, Xiaoyu Wang, Tianqiang Jin, Yu Tian, Chaoliu Dai, Crystal Widarma, Rui Song & Feng Xu. (2020) Immune checkpoint molecules in natural killer cells as potential targets for cancer immunotherapy. Signal Transduction and Targeted Therapy 5:1.
Crossref
Kuo-Ching Mei, Yu-Pei Liao, Jinhong Jiang, Michelle Chiang, Mercedeh Khazaieli, Xiangsheng Liu, Xiang Wang, Qi Liu, Chong Hyun Chang, Xiao Zhang, Juan Li, Ying Ji, Brenda Melano, Donatello Telesca, Tian Xia, Huan Meng & Andre E. Nel. (2020) Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors. ACS Nano 14:10, pages 13343-13366.
Crossref
Lilianne Beola, Laura Asín, Catarina Roma-Rodrigues, Yilian Fernández-Afonso, Raluca M. Fratila, David Serantes, Sergiu Ruta, Roy W. Chantrell, Alexandra R. Fernandes, Pedro V. Baptista, Jesús M. de la Fuente, Valeria Grazú & Lucía Gutiérrez. (2020) The Intracellular Number of Magnetic Nanoparticles Modulates the Apoptotic Death Pathway after Magnetic Hyperthermia Treatment. ACS Applied Materials & Interfaces 12:39, pages 43474-43487.
Crossref
Romain Donne, Maëva Saroul-Aïnama, Pierre Cordier, Séverine Celton-Morizur & Chantal Desdouets. (2020) Polyploidy in liver development, homeostasis and disease. Nature Reviews Gastroenterology & Hepatology 17:7, pages 391-405.
Crossref
Maria Esperanza Rodriguez-Ruiz, Ilio Vitale, Kevin J. Harrington, Ignacio Melero & Lorenzo Galluzzi. (2019) Immunological impact of cell death signaling driven by radiation on the tumor microenvironment. Nature Immunology 21:2, pages 120-134.
Crossref
Seila Lorenzo-Herrero, Christian Sordo-Bahamonde, Segundo González & Alejandro López-Soto. 2020. Tumor Immunology and Immunotherapy – Cellular Methods Part A. Tumor Immunology and Immunotherapy – Cellular Methods Part A 483 495 .
Andréa E. Tijhuis, Sarah C. Johnson & Sarah E. McClelland. (2019) The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity. Molecular Cytogenetics 12:1.
Crossref
Xin Xie, Lingman Ma, Yiran Zhou, Wen Shen, Duiyue Xu, Jie Dou, Baiyong Shen & Changlin Zhou. (2019) Polysaccharide enhanced NK cell cytotoxicity against pancreatic cancer via TLR4/MAPKs/NF-κB pathway in vitro/vivo. Carbohydrate Polymers 225, pages 115223.
Crossref
Saeid Shahrabi, Zeinab D. Zayeri, Narges Ansari, Elham H. Hadad & Elham Rajaei. (2019) Flip‐flops of natural killer cells in autoimmune diseases versus cancers: Immunologic axis. Journal of Cellular Physiology 234:10, pages 16998-17010.
Crossref
Seila Lorenzo-Herrero, Christian Sordo-Bahamonde, Segundo González & Alejandro López-Soto. 2019. Cancer Immunosurveillance. Cancer Immunosurveillance 131 139 .
Seila Lorenzo-Herrero, Christian Sordo-Bahamonde, Segundo Gonzalez & Alejandro López-Soto. 2019. Cancer Immunosurveillance. Cancer Immunosurveillance 119 130 .
Seila Lorenzo-Herrero, Alejandro López-Soto, Christian Sordo-Bahamonde, Ana Gonzalez-Rodriguez, Massimo Vitale & Segundo Gonzalez. (2018) NK Cell-Based Immunotherapy in Cancer Metastasis. Cancers 11:1, pages 29.
Crossref
Kalpana Mujoo, Clayton R. Hunt, Raj K. Pandita, Mauro Ferrari, Sunil Krishnan, John P. Cooke, Stephen Hahn & Tej K. Pandita. (2018) Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes. Molecular Cancer Research 16:8, pages 1209-1214.
Crossref
Michelle S. Levine & Andrew J. Holland. (2018) The impact of mitotic errors on cell proliferation and tumorigenesis. Genes & Development 32:9-10, pages 620-638.
Crossref
Ruth Seelige, Stephen Searles & Jack D Bui. (2018) Innate sensing of cancer's non-immunologic hallmarks. Current Opinion in Immunology 50, pages 1-8.
Crossref
Ruth Seelige, Stephen Searles & Jack D. Bui. (2017) Mechanisms regulating immune surveillance of cellular stress in cancer. Cellular and Molecular Life Sciences 75:2, pages 225-240.
Crossref
Alejandro López-Soto, Segundo Gonzalez, Carlos López-Larrea & Guido Kroemer. (2017) Immunosurveillance of Malignant Cells with Complex Karyotypes. Trends in Cell Biology 27:12, pages 880-884.
Crossref
Loredana Cifaldi, Franco Locatelli, Emiliano Marasco, Lorenzo Moretta & Vito Pistoia. (2017) Boosting Natural Killer Cell-Based Immunotherapy with Anticancer Drugs: a Perspective. Trends in Molecular Medicine 23:12, pages 1156-1175.
Crossref
Alessandra Zingoni, Cinzia Fionda, Cristiana Borrelli, Marco Cippitelli, Angela Santoni & Alessandra Soriani. (2017) Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance. Frontiers in Immunology 8.
Crossref
Jiacheng Bi & Zhigang Tian. (2017) NK Cell Exhaustion. Frontiers in Immunology 8.
Crossref
Nidhi Gera & Kenneth D. Swanson. 2016. Alternating Electric Fields Therapy in Oncology. Alternating Electric Fields Therapy in Oncology 1 14 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.