Advanced search
Publication Cover
OncoImmunology Volume 5, 2016 - Issue 4
Submit an article Journal homepage
881
Views
16
CrossRef citations to date
0
Altmetric
Original Research

Vemurafenib and ipilimumab: A promising combination? Results of a case series

Jessica C. HasselDepartment of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, GermanyCorrespondence[email protected]
,
Sophia B. LeeDepartment of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany
,
Frank MeissDepartment of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany
,
Friedegund MeierDepartment of Dermatology, University Hospital Tübingen, Tübingen, Germany
,
Antonia Dimitrakopoulou-StraussClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
,
Dirk JägerDepartment of Medical Oncology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany
&
Alexander H. EnkDepartment of Dermatology and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany
 show all
Article: e1101207 | Received 10 Aug 2015, Accepted 23 Sep 2015, Published online: 08 Apr 2016

Citations (16)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Marcel A. Deken, Jules Gadiot, Ekaterina S. Jordanova, Ruben Lacroix, Melissa van Gool, Paula Kroon, Cristina Pineda, Marnix H. Geukes Foppen, Richard Scolyer, Ji-Ying Song, Inge Verbrugge, Christoph Hoeller, Reinhard Dummer, John B. A. G. Haanen, Georgina V. Long & Christian U. Blank. (2016) Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma. OncoImmunology 5:12.
Read now
Teresa Amaral, Noura Nouri & Claus Garbe. (2016) The safety and efficacy of cobimetinib for the treatment of BRAF V600E or V600K melanoma. Expert Review of Anticancer Therapy 16:7, pages 705-715.
Read now

Articles from other publishers (14)

Shixin Zhao, Yongkang Zhu, Hengdeng Liu, Xuefeng He & Julin Xie. (2023) System analysis based on the pyroptosis-related genes identifes GSDMD as a novel therapy target for skin cutaneous melanoma. Journal of Translational Medicine 21:1.
Crossref
Maximilian Haist, Henner Stege, Michael Kuske, Julia Bauer, Annika Klumpp, Stephan Grabbe & Matthias Bros. (2023) Combination of immune-checkpoint inhibitors and targeted therapies for melanoma therapy: The more, the better?. Cancer and Metastasis Reviews 42:2, pages 481-505.
Crossref
Son Hai Vu, Preethi Vetrivel, Jongmin Kim & Myeong-Sok Lee. (2022) Cancer Resistance to Immunotherapy: Molecular Mechanisms and Tackling Strategies. International Journal of Molecular Sciences 23:18, pages 10906.
Crossref
Emily J. Lelliott, Grant A. McArthur, Jane Oliaro & Karen E. Sheppard. (2021) Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma. Frontiers in Immunology 12.
Crossref
Christos Sachpekidis & Antonia Dimitrakopoulou-Strauss. 2020. Atlas of Response to Immunotherapy. Atlas of Response to Immunotherapy 55 65 .
Ester Simeone, Antonio M Grimaldi, Lucia Festino, Claudia Trojaniello, Maria G Vitale, Vito Vanella, Marco Palla & Paolo A Ascierto. (2019) Immunotherapy in metastatic melanoma: a novel scenario of new toxicities and their management. Melanoma Management 6:4, pages MMT30.
Crossref
Christos Sachpekidis, Annette Kopp-Schneider, Lara Hakim-Meibodi, Antonia Dimitrakopoulou-Strauss & Jessica C. Hassel. (2019) 18F-FDG PET/CT longitudinal studies in patients with advanced metastatic melanoma for response evaluation of combination treatment with vemurafenib and ipilimumab. Melanoma Research 29:2, pages 178-186.
Crossref
Meredith S. Pelster & Rodabe N. Amaria. (2019) Combined targeted therapy and immunotherapy in melanoma: a review of the impact on the tumor microenvironment and outcomes of early clinical trials. Therapeutic Advances in Medical Oncology 11, pages 175883591983082.
Crossref
Yara Abdou, Ankita Kapoor, Lamya Hamad & Marc S. Ernstoff. (2019) Combination of pembrolizumab and imatinib in a patient with double KIT mutant melanoma. Medicine 98:44, pages e17769.
Crossref
Merope Griffin, Daniele Scotto, Debra H. Josephs, Silvia Mele, Silvia Crescioli, Heather J. Bax, Giulia Pellizzari, Matthew D. Wynne, Mano Nakamura, Ricarda M. Hoffmann, Kristina M. Ilieva, Anthony Cheung, James F. Spicer, Sophie Papa, Katie E. Lacy & Sophia N. Karagiannis. (2017) BRAF inhibitors: resistance and the promise of combination treatments for melanoma. Oncotarget 8:44, pages 78174-78192.
Crossref
Aaron C. Tan, Amy B. Heimberger, Alexander M. Menzies, Nick Pavlakis & Mustafa Khasraw. (2017) Immune Checkpoint Inhibitors for Brain Metastases. Current Oncology Reports 19:6.
Crossref
David J. Hermel & Patrick A. Ott. (2017) Combining forces: the promise and peril of synergistic immune checkpoint blockade and targeted therapy in metastatic melanoma. Cancer and Metastasis Reviews 36:1, pages 43-50.
Crossref
Daniel Bauer, Felix Werth, Ha An Nguyen, Felix Kiecker & Jürgen Eberle. (2017) Critical role of reactive oxygen species (ROS) for synergistic enhancement of apoptosis by vemurafenib and the potassium channel inhibitor TRAM-34 in melanoma cells. Cell Death & Disease 8:2, pages e2594-e2594.
Crossref
. (2016) Ipilimumab/vemurafenib. Reactions Weekly 1605:1, pages 107-107.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.