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Original Research

Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS

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Article: e1114203 | Received 03 Aug 2015, Accepted 24 Oct 2015, Published online: 19 Apr 2016

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Timothy T. Spear, Yuan Wang, Thomas W. SmithJr.Jr., Patricia E. Simms, Elizabeth Garrett-Mayer, Lance M. Hellman, Brian M. Baker & Michael I. Nishimura. (2018) Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells. Molecular Therapy 26:4, pages 996-1007.
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