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OncoImmunology
Volume 5, 2016 - Issue 5
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Original Research
Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS
Ornella FranzeseDepartment of Systems Medicine, University of Tor Vergata, Rome, Italy
, Belinda PalermoDepartment of Molecular Medicine, University of Rome “La Sapienza;” Rome, Italy;Department of Research, Advanced Diagnostics and Technological Innovation, Regina Elena National Cancer Institute, Rome, Italy
, Cosmo Di DonnaDepartment of Research, Advanced Diagnostics and Technological Innovation, Regina Elena National Cancer Institute, Rome, Italy
, Isabella SperdutiBiostatistics and Scientific Direction, Regina Elena National Cancer Institute, Rome, Italy
, Virginia FerraresiDepartment of Experimental Oncology, Medical Oncology 1, Regina Elena National Cancer Institute, Rome, Italy
, Helena StabileDepartment of Molecular Medicine, University of Rome “La Sapienza;” Rome, Italy
, Angela GismondiDepartment of Molecular Medicine, University of Rome “La Sapienza;” Rome, Italy
, Angela SantoniDepartment of Molecular Medicine, University of Rome “La Sapienza;” Rome, Italy
& Paola NisticòDepartment of Research, Advanced Diagnostics and Technological Innovation, Regina Elena National Cancer Institute, Rome, ItalyCorrespondence[email protected].
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Article: e1114203
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Received 03 Aug 2015, Accepted 24 Oct 2015, Published online: 19 Apr 2016
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