Citations (52)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (7)
Yu Zhang, Xue-Li Wang, Jing-Jing Liu, Zhen-Yuan Qian, Zheng-Yang Pan, Ni-Ping Song, Hui-Yan Chen, Wei Zhang & Xin Zhang. (2023) ICOS/ICOSLG and PD-1 Co-Expression is Associated with the Progression of Colorectal Precancerous- Carcinoma Immune Microenvironment. Journal of Inflammation Research 16, pages 977-992.
Read now
Read now
Agustinus Darmadi Hariyanto, Tiara Bunga Mayang Permata & Soehartati Argadikoesoema Gondhowiardjo. (2022) Role of CD4+CD25+FOXP3+ TReg cells on tumor immunity. Immunological Medicine 45:2, pages 94-107.
Read now
Read now
Jie Sun, Xiaoquan Zhu, Yanyang Zhao, Qi Zhou, Ruomei Qi & Hui Liu. (2021) CHN1 is a Novel Prognostic Marker for Diffuse Large B-Cell Lymphoma. Pharmacogenomics and Personalized Medicine 14, pages 397-408.
Read now
Read now
Luka de Vos, Ingela Grünwald, Emma Grace Bawden, Jörn Dietrich, Kathrin Scheckenbach, Constanze Wiek, Romina Zarbl, Friedrich Bootz, Jennifer Landsberg & Dimo Dietrich. (2020) The landscape of CD28, CD80, CD86, CTLA4, and ICOS DNA methylation in head and neck squamous cell carcinomas. Epigenetics 15:11, pages 1195-1212.
Read now
Read now
Florent Amatore, Laurent Gorvel & Daniel Olive. (2020) Role of Inducible Co-Stimulator (ICOS) in cancer immunotherapy. Expert Opinion on Biological Therapy 20:2, pages 141-150.
Read now
Read now
Florent Amatore, Laurent Gorvel & Daniel Olive. (2018) Inducible Co-Stimulator (ICOS) as a potential therapeutic target for anti-cancer therapy. Expert Opinion on Therapeutic Targets 22:4, pages 343-351.
Read now
Read now
Mariona Cabo, Rienk Offringa, Laurence Zitvogel, Guido Kroemer, Aura Muntasell & Lorenzo Galluzzi. (2017) Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications. OncoImmunology 6:12.
Read now
Read now
Articles from other publishers (45)
Maxime Borgeaud, Jose Sandoval, Michel Obeid, Giuseppe Banna, Olivier Michielin, Alfredo Addeo & Alex Friedlaender. (2023) Novel targets for immune-checkpoint inhibition in cancer. Cancer Treatment Reviews 120, pages 102614.
Crossref
Crossref
Zhengchun Kang, Bingchen Chen, Xiuzhu Ma, Feihu Yan & Zhen Wang. (2023) Immune-related gene-based model predicts the survival of colorectal carcinoma and reflected various biological statuses. Frontiers in Molecular Biosciences 10.
Crossref
Crossref
Xiao‐Kai Zhan, Xi‐Kun Liu, Sen Zhang & Hong Chen. (2023) Expression and prognosis of inducible T‐cell co‐stimulator and its ligand in Chinese stage I–III lung adenocarcinoma patients. Animal Models and Experimental Medicine 6:5, pages 464-473.
Crossref
Crossref
Liang Zeng, Hui Xu, Shu-Hua Li, Shuo-Yu Xu, Kai Chen, Liang-Jun Qin, Lei Miao, Fang Wang, Ling Deng, Feng-Hua Wang, Le Li, Sha Fu, Na Liu, Ran Wang, Ying-Qing Li & Hai-Yun Wang. (2023) Cross-cohort analysis identified an immune checkpoint-based signature to predict the clinical outcomes of neuroblastoma. Journal for ImmunoTherapy of Cancer 11:5, pages e005980.
Crossref
Crossref
Sang Hyuk Lee, Seung Hwan Kim, Taek Min Nam, Ji Hwan Jang, Kyu Hong Kim, Young-Sam Lee, Minseok S. Kim, Mee-Seon Kim, Sung Yup Jin, Moonok Lee, Sung-Hun Lee & Young Zoon Kim. (2023) Epigenetic Regulation of the Expression of T Cell Stimulatory and Inhibitory Factors by Histone H3 Lysine Modification Enzymes and Its Prognostic Roles in Glioblastoma. Journal of Korean Medical Science 38:33.
Crossref
Crossref
Meenakshi Gupta, Kumari Chandan & Maryam Sarwat. (2022) Natural products and their derivatives as immune check point inhibitors: Targeting cytokine/chemokine signalling in cancer. Seminars in Cancer Biology 86, pages 214-232.
Crossref
Crossref
Jin Wang, Fei Shi & Aijun Shan. (2022) Transcriptome profile and clinical characterization of ICOS expression in gliomas. Frontiers in Oncology 12.
Crossref
Crossref
Iman M. Talaat, Noha M. Elemam, Shroque Zaher & Maha Saber-Ayad. (2022) Checkpoint molecules on infiltrating immune cells in colorectal tumor microenvironment. Frontiers in Medicine 9.
Crossref
Crossref
Marius Külp, Anna Lena Siemund, Patrizia Larghero, Alissa Dietz, Julia Alten, Gunnar Cario, Cornelia Eckert, Aurélie Caye-Eude, Hélène Cavé, Michela Bardini, Giovanni Cazzaniga, Paola De Lorenzo, Maria Grazia Valsecchi, Laura Diehl, Halvard Bonig, Claus Meyer & Rolf Marschalek. (2022) The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t(4;11) acute lymphoblastic leukemia. iScience 25:7, pages 104613.
Crossref
Crossref
Abdo Alnabulsi, Tiehui Wang, Wei Pang, Marius Ionescu, Stephanie G Craig, Matthew P Humphries, Kris McCombe, Manuel Salto Tellez, Ayham Alnabulsi & Graeme I Murray. (2022) Identification of a prognostic signature in colorectal cancer using combinatorial algorithm‐driven analysis. The Journal of Pathology: Clinical Research 8:3, pages 245-256.
Crossref
Crossref
Nicolas Huyghe, Elena Benidovskaya, Philippe Stevens & Marc Van den Eynde. (2022) Biomarkers of Response and Resistance to Immunotherapy in Microsatellite Stable Colorectal Cancer: Toward a New Personalized Medicine. Cancers 14:9, pages 2241.
Crossref
Crossref
Xinru Hu, Yuyue Qiu, Xiaoping Zeng & Hongmei Wang. (2022) Exosomes reveal the dual nature of radiotherapy in tumor immunology. Cancer Science 113:4, pages 1105-1112.
Crossref
Crossref
Jennifer Londregan, Jeffrey Maslanka, Naomi Goldman, John Somerville & James E. Riggs. (2022) IgD ligation allows peritoneal cavity B cell proliferation. Immunobiology 227:2, pages 152181.
Crossref
Crossref
Sai Batchu, Owen Seamus Henry & Siyuan Yu. (2021) Transcriptomic deconvolution reveals unique tumor microenvironmental interactions across intracranial meningioma WHO grades. Gene Reports 25, pages 101388.
Crossref
Crossref
Grégory Noël, Mireille Langouo Fontsa, Soizic Garaud, Pushpamali De Silva, Alexandre de Wind, Gert G. Van den Eynden, Roberto Salgado, Anaïs Boisson, Hanne Locy, Noémie Thomas, Cinzia Solinas, Edoardo Migliori, Céline Naveaux, Hugues Duvillier, Sophie Lucas, Ligia Craciun, Kris Thielemans, Denis Larsimont & Karen Willard-Gallo. (2021) Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity. Journal of Clinical Investigation 131:19.
Crossref
Crossref
Daoliang Song, Jie Tian, Xuefeng Han & Xin Li. (2021) A model of seven immune checkpoint-related genes predicting overall survival for head and neck squamous cell carcinoma. European Archives of Oto-Rhino-Laryngology 278:9, pages 3467-3477.
Crossref
Crossref
Daniel DiToro & Rajatava Basu. (2021) Emerging Complexity in CD4+T Lineage Programming and Its Implications in Colorectal Cancer. Frontiers in Immunology 12.
Crossref
Crossref
Violaine Randrian, Camille Evrard & David Tougeron. (2021) Microsatellite Instability in Colorectal Cancers: Carcinogenesis, Neo-Antigens, Immuno-Resistance and Emerging Therapies. Cancers 13:12, pages 3063.
Crossref
Crossref
Chao Li, Tao Liu, Yi Liu, Jiantao Zhang & Didi Zuo. (2021) Prognostic value of tumour microenvironment‐related genes by TCGA database in rectal cancer. Journal of Cellular and Molecular Medicine 25:12, pages 5811-5822.
Crossref
Crossref
Jii Bum Lee, Sang-Jun Ha & Hye Ryun Kim. (2021) Clinical Insights Into Novel Immune Checkpoint Inhibitors. Frontiers in Pharmacology 12.
Crossref
Crossref
Matthew Alderdice, Stephanie G Craig, Matthew P Humphries, Alan Gilmore, Nicole Johnston, Victoria Bingham, Vicky Coyle, Seedevi Senevirathne, Daniel B Longley, Maurice B Loughrey, Stephen McQuaid, Jacqueline A James, Manuel Salto-Tellez, Mark Lawler & Darragh G McArt. (2021)
Evolutionary genetic algorithm identifies
IL2RB
as a potential predictive biomarker for immune-checkpoint therapy in colorectal cancer
. NAR Genomics and Bioinformatics 3:2.
Crossref
Crossref
Lena Seifert, Ioana Plesca, Luise Müller, Ulrich Sommer, Max Heiduk, Janusz von Renesse, David Digomann, Jessica Glück, Anna Klimova, Jürgen Weitz, Marc Schmitz & Adrian M. Seifert. (2021) LAG-3-Expressing Tumor-Infiltrating T Cells Are Associated with Reduced Disease-Free Survival in Pancreatic Cancer. Cancers 13:6, pages 1297.
Crossref
Crossref
Matthew P. Humphries, Stephanie G. Craig, Rafal Kacprzyk, Natalie C. Fisher, Victoria Bingham, Stephen McQuaid, Graeme I. Murray, Damian McManus, Richard C. Turkington, Jacqueline James & Manuel Salto-Tellez. (2020) The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation. BMC Cancer 20:1.
Crossref
Crossref
Deena M. Maurer, Juraj Adamik, Patricia M. Santos, Jian Shi, Michael R. Shurin, John M. Kirkwood, Walter J. Storkus & Lisa H. Butterfield. (2020) Dysregulated NF-κB–Dependent ICOSL Expression in Human Dendritic Cell Vaccines Impairs T-cell Responses in Patients with Melanoma. Cancer Immunology Research 8:12, pages 1554-1567.
Crossref
Crossref
Richard C.A. Sainson, Anil K. Thotakura, Miha Kosmac, Gwenoline Borhis, Nahida Parveen, Rachael Kimber, Joana Carvalho, Simon J. Henderson, Kerstin L. Pryke, Tracey Okell, Siobhan O'Leary, Stuart Ball, Cassie Van Krinks, Lauriane Gamand, Emma Taggart, Eleanor J. Pring, Hanif Ali, Hannah Craig, Vivian W.Y. Wong, Qi Liang, Robert J. Rowlands, Morgane Lecointre, Jamie Campbell, Ian Kirby, David Melvin, Volker Germaschewski, Elisabeth Oelmann, Sonia Quaratino & Matthew McCourt. (2020) An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression. Cancer Immunology Research 8:12, pages 1568-1582.
Crossref
Crossref
Dan-Yang Li & Xian-Zhi Xiong. (2020) ICOS+ Tregs: A Functional Subset of Tregs in Immune Diseases. Frontiers in Immunology 11.
Crossref
Crossref
Liang Guo, Chuanlei Wang, Xiang Qiu, Xiaoyu Pu & Pengyu Chang. (2020) Colorectal Cancer Immune Infiltrates: Significance in Patient Prognosis and Immunotherapeutic Efficacy. Frontiers in Immunology 11.
Crossref
Crossref
Nausicaa Clemente, Elena Boggio, Luca Casimiro Gigliotti, Davide Raineri, Benedetta Ferrara, Gianluca Miglio, Monica Argenziano, Annalisa Chiocchetti, Giuseppe Cappellano, Francesco Trotta, Fabrizio Caldera, Maria Teresa Capucchio, Junji Yagi, Maria Josè Rojo, Filippo Renò, Roberta Cavalli, Chiara Dianzani & Umberto Dianzani. (2020) Immunotherapy of experimental melanoma with ICOS-Fc loaded in biocompatible and biodegradable nanoparticles. Journal of Controlled Release 320, pages 112-124.
Crossref
Crossref
Q. Jiao, Q. Qian, C. Liu, Y. Luo, F. Fang, M. Wang, J. Ji, H. Qian, X. Zhang & M. Maurer. (2019) T helper 22 cells from Han Chinese patients with atopic dermatitis exhibit high expression of inducible T‐cell costimulator. British Journal of Dermatology 182:3, pages 648-657.
Crossref
Crossref
Yiwen Lu, Qiyi Zhao, Jian-You Liao, Erwei Song, Qidong Xia, Jiayao Pan, Yihong Li, Jiaqian Li, Boxuan Zhou, Yingying Ye, Can Di, Shubin Yu, Yunjie Zeng & Shicheng Su. (2020) Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity. Cell 180:6, pages 1081-1097.e24.
Crossref
Crossref
Varun Sasidharan Nair, Salman M Toor, Rowaida Z Taha, Ayman A Ahmed, Mohamed A Kurer, Khaled Murshed, Madiha E Soofi, Khalid Ouararhni, Nehad M. Alajez, Mohamed Abu Nada & Eyad Elkord. (2020) Transcriptomic Profiling of Tumor-Infiltrating CD4+TIM-3+ T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer Patients. Vaccines 8:1, pages 71.
Crossref
Crossref
Geng Zhang, Yi Xu, Sen Zhang & Huifang Zhou. (2020) The ICOSL Expression Predicts Better Prognosis for Nasopharyngeal Carcinoma via Enhancing Oncoimmunity. BioMed Research International 2020, pages 1-9.
Crossref
Crossref
Seongju Jeong & Su-Hyung Park. (2020) Co-Stimulatory Receptors in Cancers and Their Implications for Cancer Immunotherapy. Immune Network 20:1.
Crossref
Crossref
Cinzia Solinas, Chunyan Gu-Trantien & Karen Willard-Gallo. (2020) The rationale behind targeting the ICOS-ICOS ligand costimulatory pathway in cancer immunotherapy. ESMO Open 5:1, pages e000544.
Crossref
Crossref
Geng Zhang, Yi Xu & Huifang Zhou. (2018) The Infiltration of ICOS+ Cells in Nasopharyngeal Carcinoma is Beneficial for Improved Prognosis. Pathology & Oncology Research 26:1, pages 365-370.
Crossref
Crossref
Guillaume Beyrend, Esmé van der Gracht, Ayse Yilmaz, Suzanne van Duikeren, Marcel Camps, Thomas Höllt, Anna Vilanova, Vincent van Unen, Frits Koning, Noel F. C. C. de Miranda, Ramon Arens & Ferry Ossendorp. (2019) PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors. Journal for ImmunoTherapy of Cancer 7:1.
Crossref
Crossref
Shuhao Zhang, Shyamal Goswami, Jiaqiang Ma, Lu Meng, Youping Wang, Fangming Zhu, Dandan Zhang, Shan Zheng, Rui Dong, Xianmin Xiao, Xiaoming Zhang & Gong Chen. (2019) CD4+T Cell Subset Profiling in Biliary Atresia Reveals ICOS− Regulatory T Cells as a Favorable Prognostic Factor. Frontiers in Pediatrics 7.
Crossref
Crossref
Gangjian Wang, Xiaorui Fu, Yu Chang, Xin Li, Xiaolong Wu, Ling Li, Lei Zhang, Zhenchang Sun, Xudong Zhang & Mingzhi Zhang. (2019) B7-CD28 gene family expression is associated with prognostic and immunological characteristics of diffuse large B-cell lymphoma. Aging 11:12, pages 3939-3957.
Crossref
Crossref
Rituparna Chakrabarti, Bhavya Kapse & Gayatri Mukherjee. (2019) Soluble immune checkpoint molecules: Serum markers for cancer diagnosis and prognosis. CANCER REPORTS, pages e1160.
Crossref
Crossref
Samantha Burugu, Amanda R. Dancsok & Torsten O. Nielsen. (2018) Emerging targets in cancer immunotherapy. Seminars in Cancer Biology 52, pages 39-52.
Crossref
Crossref
S. Assoun, M.-A. Benderra, A. Géraud, A. Bayle, A. Boilève, D. Grazziotin-Soares & J.-P. Lotz. (2018) Congrès de l’association américaine de recherche contre le cancer — AACR 2018. Oncologie 20:3-4, pages 49-70.
Crossref
Crossref
Chia-Wei Li, Yun-Ju Lai, Jennifer L. Hsu & Mien-Chie Hung. (2018) Activation of phagocytosis by immune checkpoint blockade. Frontiers of Medicine 12:4, pages 473-480.
Crossref
Crossref
Yong Mao, Cheng Wang, Fanyi Meng, Jiehong Kong, Suping Cao, Yiguo Jiang, Weipeng Wang & Dong Hua. (2018) Polymorphisms in the ICOS/CD28-ICOSL pathway are related to capecitabine-based chemotherapy response in advanced colon cancer patients. Molecular Immunology 96, pages 78-82.
Crossref
Crossref
Ya Cao, Tinghua Cao, Weidong Zhao, Fanghua He, Ye Lu, Guangbo Zhang, Hao Hu & Zhenxin Wang. (2018) Expression of B7-H2 on CD8+ T cells in colorectal cancer microenvironment and its clinical significance. International Immunopharmacology 56, pages 128-134.
Crossref
Crossref
Marius Külp, Anna Lena Siemund, Patrizia Larghero, Alissa Dietz, Julia Alten, Gunnar Cario, Cornelia Eckert, Aurelie Caye-Eude, Helene Cavé, Michela Bardini, Giovanni Cazzaniga, Paola De Lorenzo, Maria Grazia Valsecchi, Laura Diehl, Bonig Halvard, Claus Meyer & Rolf Marschalek. (2022) The Immune Checkpoint ICOSLG is a Relapse-Predicting Biomarker and Therapeutic Target in Infant t(4;11) Acute Lymphoblastic Leukemia. SSRN Electronic Journal.
Crossref
Crossref