1,930
Views
51
CrossRef citations to date
0
Altmetric
Original Research

CTLA4 blockade reduces immature myeloid cells in head and neck squamous cell carcinoma

, , , , , , & show all
Article: e1151594 | Received 19 Nov 2015, Accepted 02 Feb 2016, Published online: 28 Jun 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Xin Yu, Lijun Xu, Yongqiang Zhou, Xiaorong Zhou, Lei Yang & Yan Zhou. (2023) NUP62CL as an Immunological and Prognostic Biomarker of Oral Squamous Cell Carcinoma. Journal of Inflammation Research 16, pages 3799-3809.
Read now
Lei Wu, Guang-Tao Yu, Wei-Wei Deng, Liang Mao, Lei-Lei Yang, Si-Rui Ma, Lin-Lin Bu, Ashok B. Kulkarni, Wen-Feng Zhang, Lu Zhang & Zhi-Jun Sun. (2018) Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma. OncoImmunology 7:4.
Read now
Mariona Cabo, Rienk Offringa, Laurence Zitvogel, Guido Kroemer, Aura Muntasell & Lorenzo Galluzzi. (2017) Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications. OncoImmunology 6:12.
Read now
Claire Vanpouille-Box, Claire Lhuillier, Lucillia Bezu, Fernando Aranda, Takahiro Yamazaki, Oliver Kepp, Jitka Fucikova, Radek Spisek, Sandra Demaria, Silvia C. Formenti, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2017) Trial watch: Immune checkpoint blockers for cancer therapy. OncoImmunology 6:11.
Read now
Wei-Wei Deng, Liang Mao, Guang-Tao Yu, Lin-Lin Bu, Si-Rui Ma, Bing Liu, J. Silvio Gutkind, Ashok B. Kulkarni, Wen-Feng Zhang & Zhi-Jun Sun. (2016) LAG-3 confers poor prognosis and its blockade reshapes antitumor response in head and neck squamous cell carcinoma. OncoImmunology 5:11.
Read now

Articles from other publishers (46)

Shi-Rou Chang, Chung-Hsien Chou, Chung-Ji Liu, Yu-Cheng Lin, Hsi-Feng Tu, Kuo-Wei Chang & Shu-Chun Lin. (2023) The Concordant Disruption of B7/CD28 Immune Regulators Predicts the Prognosis of Oral Carcinomas. International Journal of Molecular Sciences 24:6, pages 5931.
Crossref
Francesco De Sanctis, Annalisa Adamo, Stefania Canè & Stefano Ugel. (2022) Targeting tumour-reprogrammed myeloid cells: the new battleground in cancer immunotherapy. Seminars in Immunopathology 45:2, pages 163-186.
Crossref
Qiaoqiao Huang, Ying Han, Edward Shen, Ziyang Feng, Yinghui Peng, Le Gao, Yan Gao, Yongting Liu, Wei Li, Ping Liu, Yihong Chen, Cao Guo, Shan Zeng, Changjing Cai & Hong Shen. (2023) MTFR2 shapes a barrier of immune microenvironment in hepatocellular carcinoma. iScience 26:1, pages 105095.
Crossref
Marcos Paulo S. Damasio, Camila Sales Nascimento, Lidia M. Andrade, Vivian L. de Oliveira & Carlos Eduardo Calzavara-Silva. (2022) The role of T-cells in head and neck squamous cell carcinoma: From immunity to immunotherapy. Frontiers in Oncology 12.
Crossref
Takuya Kato, Ryuhei Okada, Aki Furusawa, Hiroaki Wakiyama, Hideyuki Furumoto, Hiroshi Fukushima, Shuhei Okuyama, Peter L. Choyke & Hisataka Kobayashi. (2022) Comparison of the Effectiveness of IgG Antibody versus F(ab′) 2 Antibody Fragment in CTLA4-Targeted Near-Infrared Photoimmunotherapy . Molecular Pharmaceutics 19:10, pages 3600-3611.
Crossref
Zhi-Min Yang, Bing Liao, Si-Si Yang, Tong Su, Jing Zhang & Wei-Ming Wang. (2022) Predictive Role of NEK6 in Prognosis and Immune Infiltration in Head and Neck Squamous Cell Carcinoma. Frontiers in Endocrinology 13.
Crossref
Michael Kuske, Maximilian Haist, Thomas Jung, Stephan Grabbe & Matthias Bros. (2022) Immunomodulatory Properties of Immune Checkpoint Inhibitors—More than Boosting T-Cell Responses?. Cancers 14:7, pages 1710.
Crossref
Niki Gavrielatou, Panagiota Economopoulou & Amanda Psyrri. 2022.
Angeliki Datsi & Rüdiger V. Sorg. (2021) Dendritic Cell Vaccination of Glioblastoma: Road to Success or Dead End. Frontiers in Immunology 12.
Crossref
Takuya Kato, Ryuhei Okada, Aki Furusawa, Fuyuki Inagaki, Hiroaki Wakiyama, Hideyuki Furumoto, Shuhei Okuyama, Hiroshi Fukushima, Peter L. Choyke & Hisataka Kobayashi. (2021) Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models. Molecular Cancer Therapeutics 20:11, pages 2262-2273.
Crossref
Ben Ma, Hongyi Jiang, Yi Luo, Tian Liao, Weibo Xu, Xiao Wang, Chuanpeng Dong, Qinghai Ji & Yu Wang. (2021) Tumor-Infiltrating Immune-Related Long Non-Coding RNAs Indicate Prognoses and Response to PD-1 Blockade in Head and Neck Squamous Cell Carcinoma. Frontiers in Immunology 12.
Crossref
Simin Li, Zhaoyi Mai, Wenli Gu, Anthony Chukwunonso Ogbuehi, Aneesha Acharya, George Pelekos, Wanchen Ning, Xiangqiong Liu, Yupei Deng, Hanluo Li, Bernd Lethaus, Vuk Savkovic, Rüdiger Zimmerer, Dirk Ziebolz, Gerhard Schmalz, Hao Wang, Hui Xiao & Jianjiang Zhao. (2021) Molecular Subtypes of Oral Squamous Cell Carcinoma Based on Immunosuppression Genes Using a Deep Learning Approach. Frontiers in Cell and Developmental Biology 9.
Crossref
He Zhang, Guohui Qin, Hui Yu, Xu Han & Sha Zhu. (2020) Comprehensive genomic and immunophenotypic analysis of CD4 T cell infiltrating human triple-negative breast cancer. Cancer Immunology, Immunotherapy 70:6, pages 1649-1665.
Crossref
Takuya Kato, Hiroaki Wakiyama, Aki Furusawa, Peter L. Choyke & Hisataka Kobayashi. (2021) Near Infrared Photoimmunotherapy; A Review of Targets for Cancer Therapy. Cancers 13:11, pages 2535.
Crossref
Florencia Veigas, Yamil D. Mahmoud, Joaquin Merlo, Adriana Rinflerch, Gabriel Adrian Rabinovich & María Romina Girotti. (2021) Immune Checkpoints Pathways in Head and Neck Squamous Cell Carcinoma. Cancers 13:5, pages 1018.
Crossref
Sandra Ortiz-Cuaran, Jebrane Bouaoud, Andy Karabajakian, Jérôme Fayette & Pierre Saintigny. (2021) Precision Medicine Approaches to Overcome Resistance to Therapy in Head and Neck Cancers. Frontiers in Oncology 11.
Crossref
Xiuting Liu, Graham D Hogg & David G DeNardo. (2021) Rethinking immune checkpoint blockade: ‘Beyond the T cell’. Journal for ImmunoTherapy of Cancer 9:1, pages e001460.
Crossref
Liangjie Jin, Song Shen, Youju Huang, Dongdong Li & Xianzhu Yang. (2021) Corn-like Au/Ag nanorod-mediated NIR-II photothermal/photodynamic therapy potentiates immune checkpoint antibody efficacy by reprogramming the cold tumor microenvironment. Biomaterials 268, pages 120582.
Crossref
Damilola Oyewole-Said, Vanaja Konduri, Jonathan Vazquez-Perez, Scott A. Weldon, Jonathan M. Levitt & William K. Decker. (2020) Beyond T-Cells: Functional Characterization of CTLA-4 Expression in Immune and Non-Immune Cell Types. Frontiers in Immunology 11.
Crossref
Maryam Esmaily, Ali Masjedi, Shahin Hallaj, Mohsen Nabi Afjadi, Farinaz Malakotikhah, Sepideh Ghani, Armin Ahmadi, Mozhdeh Sojoodi, Hadi Hassannia, Fatemeh Atyabi, Afshin Namdar, Gholamreza Azizi, Ghasem Ghalamfarsa & Farhad Jadidi-Niaragh. (2020) Blockade of CTLA-4 increases anti-tumor response inducing potential of dendritic cell vaccine. Journal of Controlled Release 326, pages 63-74.
Crossref
Christiana M. Neophytou, Chryso Pierides, Maria-Ioanna Christodoulou, Paul Costeas, Theodora-Christina Kyriakou & Panagiotis Papageorgis. (2020) The Role of Tumor-Associated Myeloid Cells in Modulating Cancer Therapy. Frontiers in Oncology 10.
Crossref
Zhen Zhang, Jinyan Liu, Chaoqi Zhang, Feng Li, Lifeng Li, Dan Wang, Damini Chand, Fangxia Guan, Xingxing Zang & Yi Zhang. (2020) Over-Expression and Prognostic Significance of HHLA2, a New Immune Checkpoint Molecule, in Human Clear Cell Renal Cell Carcinoma. Frontiers in Cell and Developmental Biology 8.
Crossref
Luisa Barrueto, Francheska Caminero, Lindsay Cash, Courtney Makris, Purushottam Lamichhane & Rahul R. Deshmukh. (2020) Resistance to Checkpoint Inhibition in Cancer Immunotherapy. Translational Oncology 13:3, pages 100738.
Crossref
Keunok Jung, Jeong-Ah Kim, Ye-Jin Kim, Hyun Woo Lee, Chul-Ho Kim, Seokjin Haam & Yong-Sung Kim. (2020) A Neuropilin-1 Antagonist Exerts Antitumor Immunity by Inhibiting the Suppressive Function of Intratumoral Regulatory T Cells. Cancer Immunology Research 8:1, pages 46-56.
Crossref
Hong-Gang Xiong, Hao Li, Yao Xiao, Qi-Chao Yang, Lei-Lei Yang, Lei Chen, Lin-Lin Bu, Wen-Feng Zhang, Jia-Li Zhang & Zhi-Jun Sun. (2019) Long noncoding RNA MYOSLID promotes invasion and metastasis by modulating the partial epithelial-mesenchymal transition program in head and neck squamous cell carcinoma. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Lei Wu, Liang Mao, Jian-Feng Liu, Lei Chen, Guang-Tao Yu, Lei-Lei Yang, Hao Wu, Lin-Lin Bu, Ashok B. Kulkarni, Wen-Feng Zhang & Zhi-Jun Sun. (2019) Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma. Cancer Immunology Research 7:10, pages 1700-1713.
Crossref
Ronald Anderson, Annette J. Theron & Bernardo L. Rapoport. (2019) Immunopathogenesis of Immune Checkpoint Inhibitor-Related Adverse Events: Roles of the Intestinal Microbiome and Th17 Cells. Frontiers in Immunology 10.
Crossref
Yao Xiao, Hao Li, Lei-Lei Yang, Liang Mao, Cong-Cong Wu, Wen-Feng Zhang & Zhi-Jun Sun. (2019) The Expression Patterns and Associated Clinical Parameters of Human Endogenous Retrovirus-H Long Terminal Repeat-Associating Protein 2 and Transmembrane and Immunoglobulin Domain Containing 2 in Oral Squamous Cell Carcinoma. Disease Markers 2019, pages 1-9.
Crossref
Joshua D. Horton, Hannah M. Knochelmann, Terry A. Day, Chrystal M. Paulos & David M. Neskey. (2019) Immune Evasion by Head and Neck Cancer: Foundations for Combination Therapy. Trends in Cancer 5:4, pages 208-232.
Crossref
Yi Wang, Yao-Xin Lin, Sheng-Lin Qiao, Jie Wang & Hao Wang. (2019) Progress in Tumor-Associated Macrophages: From Bench to Bedside. Advanced Biosystems 3:2, pages 1800232.
Crossref
Gonçalo Boleto, Yannick Allanore & Jérôme Avouac. (2018) Targeting Costimulatory Pathways in Systemic Sclerosis. Frontiers in Immunology 9.
Crossref
Bo Yang, Tingjun Liu, Yang Qu, Hangbo Liu, Song Guo Zheng, Bin Cheng & Jianbo Sun. (2018) Progresses and Perspectives of Anti-PD-1/PD-L1 Antibody Therapy in Head and Neck Cancers. Frontiers in Oncology 8.
Crossref
Guang-Tao Yu, Liang Mao, Lei Wu, Wei-Wei Deng, Lin-Lin Bu, Jian-Feng Liu, Lei Chen, Lei-Lei Yang, Hao Wu, Wen-Feng Zhang & Zhi-Jun Sun. (2018) Inhibition of SRC family kinases facilitates anti-CTLA4 immunotherapy in head and neck squamous cell carcinoma. Cellular and Molecular Life Sciences 75:22, pages 4223-4234.
Crossref
Purushottam Lamichhane, Neha Amin, Manuj Agarwal & Narottam Lamichhane. (2018) Checkpoint Inhibition: Will Combination with Radiotherapy and Nanoparticle-Mediated Delivery Improve Efficacy?. Medicines 5:4, pages 114.
Crossref
Cong-Cong Wu, Hao Li, Yao Xiao, Lei-Lei Yang, Lei Chen, Wei-Wei Deng, Lei Wu, Wen-Feng Zhang & Zhi-Jun Sun. (2018) Over-expression of IQGAP1 indicates poor prognosis in head and neck squamous cell carcinoma. Journal of Molecular Histology 49:4, pages 389-398.
Crossref
Rebekka Bent, Lorna Moll, Stephan Grabbe & Matthias Bros. (2018) Interleukin-1 Beta—A Friend or Foe in Malignancies?. International Journal of Molecular Sciences 19:8, pages 2155.
Crossref
Lei Chen, Cong-Fa Huang, Yi-Cun Li, Wei-Wei Deng, Liang Mao, Lei Wu, Wen-Feng Zhang, Lu Zhang & Zhi-Jun Sun. (2017) Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses in head and neck squamous cell carcinoma. Cellular and Molecular Life Sciences 75:11, pages 2045-2058.
Crossref
Sophie Outh-Gauer, Marie Alt, Christophe Le Tourneau, Jérémy Augustin, Chloé Broudin, Cassandre Gasne, Thomas Denize, Haitham Mirghani, Elizabeth Fabre, Madeleine Ménard, Florian Scotte, Eric Tartour & Cécile Badoual. (2018) Immunotherapy in head and neck cancers: A new challenge for immunologists, pathologists and clinicians. Cancer Treatment Reviews 65, pages 54-64.
Crossref
W-W Deng, L Wu & Z-J Sun. (2018) Co-inhibitory immune checkpoints in head and neck squamous cell carcinoma. Oral Diseases 24:1-2, pages 120-123.
Crossref
Liang Mao, Zhi‐Li Zhao, Guang‐Tao Yu, Lei Wu, Wei‐Wei Deng, Yi‐Cun Li, Jian‐Feng Liu, Lin‐Lin Bu, Bing Liu, Ashok B. Kulkarni, Wen‐Feng Zhang, Lu Zhang & Zhi‐Jun Sun. (2017) γ‐Secretase inhibitor reduces immunosuppressive cells and enhances tumour immunity in head and neck squamous cell carcinoma. International Journal of Cancer 142:5, pages 999-1009.
Crossref
Cong-Fa Huang, Lei Chen, Yi-Cun Li, Lei Wu, Guang-Tao Yu, Wen-Feng Zhang & Zhi-Jun Sun. (2017) NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma. Journal of Experimental & Clinical Cancer Research 36:1.
Crossref
Liang Mao, Teng-Fei Fan, Lei Wu, Guang-Tao Yu, Wei-Wei Deng, Lei Chen, Lin-Lin Bu, Si-Rui Ma, Bing Liu, Yansong Bian, Ashok B. Kulkarni, Wen-Feng Zhang & Zhi-Jun Sun. (2017) Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma. Journal of Cellular and Molecular Medicine 21:9, pages 2199-2210.
Crossref
Lei Wu, Wei-Wei Deng, Cong-Fa Huang, Lin-Lin Bu, Guang-Tao Yu, Liang Mao, Wen-Feng Zhang, Bing Liu & Zhi-Jun Sun. (2017) Expression of VISTA correlated with immunosuppression and synergized with CD8 to predict survival in human oral squamous cell carcinoma. Cancer Immunology, Immunotherapy 66:5, pages 627-636.
Crossref
Michael A. Podolsky, Jacob T. Bailey, Andrew J. Gunderson, Carrie J. Oakes, Kyle Breech & Adam B. Glick. (2017) Differentiated State of Initiating Tumor Cells Is Key to Distinctive Immune Responses Seen in H-RasG12V–Induced Squamous Tumors. Cancer Immunology Research 5:3, pages 198-210.
Crossref
Sophie Outh-Gauer, Christophe Le Tourneau, Chloé Broudin, Florian Scotte, Hélène Roussel, Stéphane Hans, Marion Mandavit, Eric Tartour & Cécile Badoual. (2017) Actualités sur l’immunothérapie en pathologie des voies aérodigestives supérieures. Annales de Pathologie 37:1, pages 79-89.
Crossref
Jian-Feng Liu, Si-Rui Ma, Liang Mao, Lin-Lin Bu, Guang-Tao Yu, Yi-Cun Li, Cong-Fa Huang, Wei-Wei Deng, Ashok B. Kulkarni, Wen-Feng Zhang & Zhi-Jun Sun. (2017) T-cell immunoglobulin mucin 3 blockade drives an antitumor immune response in head and neck cancer. Molecular Oncology 11:2, pages 235-247.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.