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Original Research

Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen

Christine SedlikInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France;Centre d'Investigation Clinique Biothérapie CICBT 1428, Institut Curie, Paris, France

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Adèle HeitzmannInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France;Centre d'Investigation Clinique Biothérapie CICBT 1428, Institut Curie, Paris, France

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Sophie VielInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France

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Rafik Ait SarkouhInstitut Curie, PSL Research University, Paris, France;CNRS UMR3666/INSERM U 1143, Paris, France

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Cornélie BatisseInstitut Curie, PSL Research University, Paris, France;CNRS UMR3666/INSERM U 1143, Paris, France

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Frédéric SchmidtInstitut Curie, PSL Research University, Paris, France;CNRS UMR3666/INSERM U 1143, Paris, France

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Philippe De La RochereInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France

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Nathalie AmzallagInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France;Centre d'Investigation Clinique Biothérapie CICBT 1428, Institut Curie, Paris, France

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Eduardo OsinagaDepartamento de Inmunobiología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay;Institut Pasteur de Montevideo, Montevideo, Uruguay

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Pablo OppezzoDepartamento de Inmunobiología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay;Institut Pasteur de Montevideo, Montevideo, Uruguay

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Otto PritschDepartamento de Inmunobiología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay;Institut Pasteur de Montevideo, Montevideo, Uruguay

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Xavier Sastre-GarauDépartement de Biologie des Tumeurs, Institut Curie, Paris, France

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Pascale HubertInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France;Centre d'Investigation Clinique Biothérapie CICBT 1428, Institut Curie, Paris, France

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Sebastian AmigorenaInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France;Centre d'Investigation Clinique Biothérapie CICBT 1428, Institut Curie, Paris, FranceCorrespondence[email protected] [email protected]

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Eliane PiaggioInstitut Curie, PSL Research University, Paris, France;INSERM U932, Paris, France;Centre d'Investigation Clinique Biothérapie CICBT 1428, Institut Curie, Paris, FranceCorrespondence[email protected] [email protected]