1,751
Views
14
CrossRef citations to date
0
Altmetric
Original Research

Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen

, , , , , , , , , , , , , & show all
Article: e1171434 | Received 09 Dec 2015, Accepted 23 Mar 2016, Published online: 29 Jun 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Jillian M. Prendergast, Ana Paula Galvao da Silva, David A. Eavarone, Darius Ghaderi, Mai Zhang, Dane Brady, Joan Wicks, Julie DeSander, Jeff Behrens & Bo R. Rueda. (2017) Novel anti-Sialyl-Tn monoclonal antibodies and antibody-drug conjugates demonstrate tumor specificity and anti-tumor activity. mAbs 9:4, pages 615-627.
Read now

Articles from other publishers (13)

Yasuyuki Matsumoto & Tongzhong Ju. (2023) Aberrant Glycosylation as Immune Therapeutic Targets for Solid Tumors. Cancers 15:14, pages 3536.
Crossref
Yasuyuki Matsumoto, Nan Jia, Jamie Heimburg-Molinaro & Richard D. Cummings. (2023) Targeting Tn-positive tumors with an afucosylated recombinant anti-Tn IgG. Scientific Reports 13:1.
Crossref
Yuna Guo, Wenshuang Jia, Jingru Yang & Xianquan Zhan. (2022) Cancer glycomics offers potential biomarkers and therapeutic targets in the framework of 3P medicine. Frontiers in Endocrinology 13.
Crossref
Lucía Biscari, Cintia Daniela Kaufman, Cecilia Farré, Victoria Huhn, María Florencia Pacini, Camila Bulfoni Balbi, Karina Andrea Gómez, Ana Rosa Pérez & Andrés Alloatti. (2022) Immunization With Lipopolysaccharide-Activated Dendritic Cells Generates a Specific CD8+ T Cell Response That Confers Partial Protection Against Infection With Trypanosoma cruzi. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Charlotte Sorieul, Francesco Papi, Filippo Carboni, Simone Pecetta, Sanjay Phogat & Roberto Adamo. (2022) Recent advances and future perspectives on carbohydrate-based cancer vaccines and therapeutics. Pharmacology & Therapeutics 235, pages 108158.
Crossref
Nora Berois, Alvaro Pittini & Eduardo Osinaga. (2022) Targeting Tumor Glycans for Cancer Therapy: Successes, Limitations, and Perspectives. Cancers 14:3, pages 645.
Crossref
G. S. Maslak, G. P. Chernenko, S. V. Abramov, I. Yu. Pismenetska, I. V. Davydenko, L. M. Lushnya & Makarets M. F.. (2021) Glycobiom Lymphocytes Surface Study of Patients with B-Cell Chronic Lymphocytic Leukemia. Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6:6, pages 134-140.
Crossref
Elizabeth M. Ward, Megan E. Kizer & Barbara Imperiali. (2021) Strategies and Tactics for the Development of Selective Glycan-Binding Proteins. ACS Chemical Biology 16:10, pages 1795-1813.
Crossref
Analía Castro, Nora Berois, Antonio Malanga, Claudia Ortega, Pablo Oppezzo, Otto Pristch, Alvaro W. Mombrú, Eduardo Osinaga & Helena Pardo. (2021) Docetaxel in chitosan-based nanocapsules conjugated with an anti-Tn antigen mouse/human chimeric antibody as a promising targeting strategy of lung tumors. International Journal of Biological Macromolecules 182, pages 806-814.
Crossref
Ming-Chen Yang, Chi-Sheng Shia, Wan-Fen Li, Chun-Chung Wang, I-Ju Chen, Teng-Yi Huang, Yu-Jung Chen, Hui-Wen Chang, Chi-Huan Lu, Yueh-Chin Wu, Nan-Hsuan Wang, Jiann-Shiun Lai, Cheng-Der Yu & Ming-Tain Lai. (2021) Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate. Molecular Cancer Therapeutics 20:6, pages 1121-1132.
Crossref
Natalia Rodrigues Mantuano, Marina Natoli, Alfred Zippelius & Heinz Läubli. (2020) Tumor-associated carbohydrates and immunomodulatory lectins as targets for cancer immunotherapy. Journal for ImmunoTherapy of Cancer 8:2, pages e001222.
Crossref
Park, Lee, Byeon, Shin, Choi, Park & Shin. (2019) Pharmacokinetic and Metabolism Studies of Monomethyl Auristatin F via Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry. Molecules 24:15, pages 2754.
Crossref
Xingchen Pang, Hongjiao Li, Feng Guan & Xiang Li. (2018) Multiple Roles of Glycans in Hematological Malignancies. Frontiers in Oncology 8.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.