OncoImmunology, Volume 5, Issue 7 (2016)

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OncoImmunology, Volume 5, Issue 7 (2016)

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Author's View

Opinion
MHC-multimer guided isolation of neoepitopes specific T cells as a potent-personalized cancer treatment strategy
Roni Bareli & Cyrille J. Cohen
Article: e1159370
Published online: 11 Jul 2016
AbstractforMHC-multimer guided isolation of neoepitopes specific T cells as a potent-personalized cancer treatment strategy | Full Text | References | PDF (363.6 KB)
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Brief Report

Brief Report
Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition
Mohammed S. Chaudhry, Kimberly C. Gilmour, Imran G. House, Mark Layton, Nicki Panoskaltsis, Mamta Sohal, Joseph A. Trapani & Ilia Voskoboinik
Article: e1179415
Published online: 30 Jun 2016
AbstractforMissense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition | Full Text | References | PDF (442.7 KB)
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Brief Report
Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop
Roch Houot, Philippe Gaulard, Robert Schreiber, Ira Mellman, Olivier Lambotte, Pierre G. Coulie, Thierry Fest, Alan Korman, Ronald Levy, Margaret Shipp, Karin Tarte, Holbrook Kohrt, Aurélien Marabelle, Stephen Ansell, Hervé Watier, Andrea van Elsas, Arun Balakumaran, Frederick Arce Vargas, Sergio A. Quezada, Gilles Salles & Daniel Olive
Article: e1186323
Published online: 15 Jul 2016
AbstractforImmunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop | Full Text | References | PDF (484.5 KB)
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MIATA Compliant Research Paper

Article
PEG-rIL-10 treatment decreases FoxP3+ Tregs despite upregulation of intratumoral IDO
Ivan H. Chan, Victoria Wu, Melissa Bilardello, Brett Jorgenson, Harminder Bal, Scott McCauley, Peter Van Vlasselaer & John B. Mumm
Article: e1197458
Published online: 15 Jul 2016
AbstractforPEG-rIL-10 treatment decreases FoxP3+ Tregs despite upregulation of intratumoral IDO | Full Text | References | PDF (1.3 MB) | Supplemental
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Original Research

Article
Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy
Rikke B. Holmgaard, Alexandra Brachfeld, Billel Gasmi, David R. Jones, Marissa Mattar, Thompson Doman, Mary Murphy, David Schaer, Jedd D. Wolchok & Taha Merghoub
Article: e1151595
Published online: 23 Jun 2016
AbstractforTiming of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy | Full Text | References | PDF (1.1 MB)
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Article
Combined treatment with dabrafenib and trametinib with immune-stimulating antibodies for BRAF mutant melanoma
Blanca Homet Moreno, Stephen Mok, Begonya Comin-Anduix, Siwen Hu-Lieskovan & Antoni Ribas
Article: e1052212
Published online: 29 Jun 2016
AbstractforCombined treatment with dabrafenib and trametinib with immune-stimulating antibodies for BRAF mutant melanoma | Full Text | References | PDF (440.3 KB) | Supplemental
  • 3558 Views
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Open Access
Article
Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer
Rosemary Millen, Jordane Malaterre, Ryan S. Cross, Sandra Carpinteri, Jayesh Desai, Ben Tran, Phillip Darcy, Peter Gibbs, Oliver Sieber, Nikolajs Zeps, Paul Waring, Stephen Fox, Lloyd Pereira & Robert G. Ramsay
Article: e1149667
Published online: 29 Jun 2016
AbstractforImmunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer | Full Text | References | PDF (1.4 MB) | Supplemental
  • 1460 Views
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Article
Extracellular HSP110 skews macrophage polarization in colorectal cancer
Kevin Berthenet, Christophe Boudesco, Ada Collura, Magali Svrcek, Sarah Richaud, Arlette Hammann, Sebastien Causse, Nadhir Yousfi, Kristell Wanherdrick, Laurence Duplomb, Alex Duval, Carmen Garrido & Gaetan Jego
Article: e1170264
Published online: 29 Jun 2016
AbstractforExtracellular HSP110 skews macrophage polarization in colorectal cancer | Full Text | References | PDF (1.1 MB) | Supplemental
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Article
Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen
Christine Sedlik, Adèle Heitzmann, Sophie Viel, Rafik Ait Sarkouh, Cornélie Batisse, Frédéric Schmidt, Philippe De La Rochere, Nathalie Amzallag, Eduardo Osinaga, Pablo Oppezzo, Otto Pritsch, Xavier Sastre-Garau, Pascale Hubert, Sebastian Amigorena & Eliane Piaggio
Article: e1171434
Published online: 29 Jun 2016
AbstractforEffective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen | Full Text | References | PDF (1.3 MB)
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Article
Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer
Eleonora Timperi, Ilenia Pacella, Valeria Schinzari, Chiara Focaccetti, Luca Sacco, Francesco Farelli, Roberto Caronna, Gabriella Del Bene, Flavia Longo, Antonio Ciardi, Sergio Morelli, Anna Rita Vestri, Piero Chirletti, Vincenzo Barnaba & Silvia Piconese
Article: e1175800
Published online: 29 Jun 2016
AbstractforRegulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer | Full Text | References | PDF (1.2 MB) | Supplemental
  • 2348 Views
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Article
PD-L1 expression as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with hepatocellular carcinoma
Chang-Long Chen, Qiu-Zhong Pan, Jing-Jing Zhao, Ying Wang, Yong-Qiang Li, Qi-Jing Wang, Ke Pan, De-Sheng Weng, Shan-Shan Jiang, Yan Tang, Xiao-Fei Zhang, Hong-Xia Zhang, Zi-Qi Zhou, Yi-Xin Zeng & Jian-Chuan Xia
Article: e1176653
Published online: 29 Jun 2016
AbstractforPD-L1 expression as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with hepatocellular carcinoma | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2138 Views
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Article
Calreticulin expression: Interaction with the immune infiltrate and impact on survival in patients with ovarian and non-small cell lung cancer
Gautier Stoll, Kristina Iribarren, Judith Michels, Alexandra Leary, Laurence Zitvogel, Isabelle Cremer & Guido Kroemer
Article: e1177692
Published online: 29 Jun 2016
AbstractforCalreticulin expression: Interaction with the immune infiltrate and impact on survival in patients with ovarian and non-small cell lung cancer | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1568 Views
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Article
Proof of concept study with an HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform
Josef Singer, Krisztina Manzano-Szalai, Judit Fazekas, Kathrin Thell, Anna Bentley-Lukschal, Caroline Stremnitzer, Franziska Roth-Walter, Margit Weghofer, Mirko Ritter, Kerstin Pino Tossi, Markus Hörer, Uwe Michaelis & Erika Jensen-Jarolim
Article: e1171446
Published online: 30 Jun 2016
AbstractforProof of concept study with an HER-2 mimotope anticancer vaccine deduced from a novel AAV-mimotope library platform | Full Text | References | PDF (924.2 KB) | Supplemental
  • 2572 Views
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Article
The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27
Sènan M. d’Almeida, Gilles Kauffenstein, Charlotte Roy, Laetitia Basset, Loukas Papargyris, Daniel Henrion, Véronique Catros, Norbert Ifrah, Philippe Descamps, Anne Croue, Pascale Jeannin, Marc Grégoire, Yves Delneste & Julie Tabiasco
Article: e1178025
Published online: 30 Jun 2016
AbstractforThe ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27 | Full Text | References | PDF (848.1 KB) | Supplemental
  • 2234 Views
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Article
TLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models
Felipe V. Pereira, Amanda C. L. Melo, Filipe M. de Melo, Diego Mourão-Sá, Priscila Silva, Rodrigo Berzaghi, Carolina C. A. Herbozo, Jordana Coelho-dos-Reis, Jorge A. Scutti, Clarice S. T. Origassa, Rosana M. Pereira, Luis Juliano, Maria Aparecida Juliano, Adriana K. Carmona, Niels O. S. Câmara, Moriya Tsuji, Luiz R. Travassos & Elaine G. Rodrigues
Article: e1178420
Published online: 30 Jun 2016
AbstractforTLR4-mediated immunomodulatory properties of the bacterial metalloprotease arazyme in preclinical tumor models | Full Text | References | PDF (1.6 MB) | Supplemental
  • 1115 Views
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Article
Progressive natural killer cell dysfunction associated with alterations in subset proportions and receptor expression in soft-tissue sarcoma patients
Veit Bücklein, Tina Adunka, Anna N. Mendler, Rolf Issels, Marion Subklewe, Jan C. Schmollinger & Elfriede Noessner
Article: e1178421
Published online: 30 Jun 2016
AbstractforProgressive natural killer cell dysfunction associated with alterations in subset proportions and receptor expression in soft-tissue sarcoma patients | Full Text | References | PDF (1,016.6 KB) | Supplemental
  • 1236 Views
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Article
MHC class II tetramer analyses in AE37-vaccinated prostate cancer patients reveal vaccine-specific polyfunctional and long-lasting CD4+ T-cells
Eleftheria A. Anastasopoulou, Ioannis F. Voutsas, Michael Papamichail, Constantin N. Baxevanis & Sonia A. Perez
Article: e1178439
Published online: 30 Jun 2016
AbstractforMHC class II tetramer analyses in AE37-vaccinated prostate cancer patients reveal vaccine-specific polyfunctional and long-lasting CD4+ T-cells | Full Text | References | PDF (1.1 MB) | Supplemental
  • 966 Views
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Article
Programmed death ligand 1 as an indicator of pre-existing adaptive immune responses in human hepatocellular carcinoma
Qian-Kun Xie, Yu-Jie Zhao, Tao Pan, Ning Lyu, Lu-Wen Mu, Shao-Long Li, Mu-De Shi, Zhen-Feng Zhang, Peng-Hui Zhou & Ming Zhao
Article: e1181252
Published online: 30 Jun 2016
AbstractforProgrammed death ligand 1 as an indicator of pre-existing adaptive immune responses in human hepatocellular carcinoma | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1957 Views
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Article
Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice
Ava Vila-Leahey, Sharon A. Oldford, Paola A. Marignani, Jun Wang, Ian D. Haidl & Jean S. Marshall
Article: e1151591
Published online: 01 Jul 2016
AbstractforRanitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice | Full Text | References | PDF (1.2 MB) | Supplemental
  • 2773 Views
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Article
Tumor-released autophagosomes induce IL-10-producing B cells with suppressive activity on T lymphocytes via TLR2-MyD88-NF-κB signal pathway
Meng Zhou, Zhifa Wen, Feng Cheng, Jie Ma, Weixia Li, Hongyan Ren, Yemeng Sheng, Huixia Dong, Liwei Lu, Hong-Ming Hu & Li-Xin Wang
Article: e1180485
Published online: 01 Jul 2016
AbstractforTumor-released autophagosomes induce IL-10-producing B cells with suppressive activity on T lymphocytes via TLR2-MyD88-NF-κB signal pathway | Full Text | References | PDF (1.5 MB) | Supplemental
  • 2477 Views
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Article
Plasma Chromogranin A as a marker of cardiovascular involvement in Erdheim–Chester disease
Elisabetta Ferrero, Angelo Corti, Julien Haroche, Daniela Belloni, Barbara Colombo, Alvise Berti, Giulio Cavalli, Corrado Campochiaro, Antonello Villa, Fleur Cohen-Aubart, Zahir Amoura, Claudio Doglioni, Lorenzo Dagna & Marina Ferrarini
Article: e1181244
Published online: 01 Jul 2016
AbstractforPlasma Chromogranin A as a marker of cardiovascular involvement in Erdheim–Chester disease | Full Text | References | PDF (805.3 KB)
  • 923 Views
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Article
BRAF V600E mutation correlates with suppressive tumor immune microenvironment and reduced disease-free survival in Langerhans cell histiocytosis
Kaixuan Zeng, Zhe Wang, Koichi Ohshima, Yixiong Liu, Weichen Zhang, Lu Wang, Linni Fan, Mingyang Li, Xia Li, Yingmei Wang, Zhou Yu, Qingguo Yan, Shuangping Guo, Jie Wei & Ying Guo
Article: e1185582
Published online: 01 Jul 2016
AbstractforBRAF V600E mutation correlates with suppressive tumor immune microenvironment and reduced disease-free survival in Langerhans cell histiocytosis | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1783 Views
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Article
Large-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas
Marie Tosolini, Christelle Algans, Frédéric Pont, Bernard Ycart & Jean-Jacques Fournié
Article: e1188246
Published online: 01 Jul 2016
AbstractforLarge-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1938 Views
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Article
Intra-cheek immunization as a novel vaccination route for therapeutic vaccines of head and neck squamous cell carcinomas using plasmo virus-like particles
Rodney Macedo, Juliette Rochefort, Maude Guillot-Delost, Kae Tanaka, Aline Le Moignic, Clara Noizat, Claude Baillou, Véronique Mateo, Antoine F. Carpentier, Eric Tartour, Chloé Bertolus, Bertrand Bellier, Géraldine Lescaille & François M. Lemoine
Article: e1164363
Published online: 06 Jul 2016
AbstractforIntra-cheek immunization as a novel vaccination route for therapeutic vaccines of head and neck squamous cell carcinomas using plasmo virus-like particles | Full Text | References | PDF (1.2 MB) | Supplemental
  • 989 Views
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Article
The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells
Isabel Gonçalves Silva, Laura Rüegg, Bernhard F. Gibbs, Marco Bardelli, Alexander Fruehwirth, Luca Varani, Steffen M. Berger, Elizaveta Fasler-Kan & Vadim V. Sumbayev
Article: e1195535
Published online: 29 Jun 2016
AbstractforThe immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells | Full Text | References | PDF (1.4 MB) | Supplemental
  • 2450 Views
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Article
Ligand–receptor dissociated expression explains high TSLP without prognostic impact in human primary head and neck squamous cell carcinoma
Maude Guillot-Delost, Lia Guilleré, Frédérique Berger, Aurore Ventre, Paula Michea, Philémon Sirven, Lucia Pattarini, Alix Scholer-Dahirel, Fatima-Zahra Kebir, Michel Huerre, Olfa Chouchane-Mlik, Emmanuelle Lappartient, José Rodriguez, Thomas Jouffroy, Jerzy Klijanienko, André Nicolas, Xavier Sastre-Garau, Sofia Honorio, Véronique Mosseri, Nelly Le Peltier, Marie-Paule Sablin, Christophe Le Tourneau, Éric Tartour, Cécile Badoual & Vassili Soumelis
Article: e1179414
Published online: 13 Jul 2016
AbstractforLigand–receptor dissociated expression explains high TSLP without prognostic impact in human primary head and neck squamous cell carcinoma | Full Text | References | PDF (1.2 MB) | Supplemental
  • 863 Views
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Article
The association of clinical outcome and peripheral T-cell subsets in metastatic colorectal cancer patients receiving first-line FOLFIRI plus bevacizumab therapy
Mario Roselli, Vincenzo Formica, Vittore Cereda, Caroline Jochems, Jacob Richards, Italia Grenga, Augusto Orlandi, Patrizia Ferroni, Fiorella Guadagni & Jeffrey Schlom
Article: e1188243
Published online: 13 Jul 2016
AbstractforThe association of clinical outcome and peripheral T-cell subsets in metastatic colorectal cancer patients receiving first-line FOLFIRI plus bevacizumab therapy | Full Text | References | PDF (825 KB) | Supplemental
  • 1072 Views
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Article
Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity
Fernando Souza-Fonseca-Guimaraes, Stephen J. Blake, Amani Makkouk, Cariad Chester, Holbrook E. Kohrt & Mark J. Smyth
Article: e1192740
Published online: 13 Jul 2016
AbstractforAnti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity | Full Text | References | PDF (1.3 MB) | Supplemental
  • 1318 Views
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Article
The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells
Sonja Textor, Felicitas Bossler, Kai-Oliver Henrich, Moritz Gartlgruber, Julia Pollmann, Nathalie Fiegler, Annette Arnold, Frank Westermann, Nina Waldburger, Kai Breuhahn, Sven Golfier, Mathias Witzens-Harig & Adelheid Cerwenka
Article: e1116674
Published online: 28 Jul 2016
AbstractforThe proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells | Full Text | References | PDF (1,012.9 KB) | Supplemental
  • 1719 Views
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Article
Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition
M. Kuttke, E. Sahin, J. Pisoni, S. Percig, A. Vogel, D. Kraemmer, L. Hanzl, J. S. Brunner, H. Paar, K. Soukup, A. Halfmann, A. M. Dohnal, C. W. Steiner, S. Blüml, J. Basilio, B. Hochreiter, M. Salzmann, B. Hoesel, G. Lametschwandtner, R. Eferl, J. A. Schmid & G. Schabbauer
Article: e1164918
Published online: 28 Mar 2016
AbstractforMyeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition | Full Text | References | PDF (1.6 MB) | Supplemental
  • 1699 Views
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Article
CD169 identifies an activated CD8+ T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients
Jiali Zhang, Jing Xu, Rong-xin Zhang, Yi Zhang, Qing-jian Ou, Jin-qing Li, Ze-zhou Jiang, Xiao-jun Wu, Yu-jing Fang & Limin Zheng
Article: e1177690
Published online: 15 Jul 2016
AbstractforCD169 identifies an activated CD8+ T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients | Full Text | References | PDF (1.2 MB) | Supplemental
  • 1490 Views
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Article
IL12-mediated sensitizing of T-cell receptor-dependent and -independent tumor cell killing
Matthias Braun, Marie L. Ress, Young-Eun Yoo, Claus J. Scholz, Matthias Eyrich, Paul G. Schlegel & Matthias Wölfl
Article: e1188245
Published online: 11 Jul 2016
AbstractforIL12-mediated sensitizing of T-cell receptor-dependent and -independent tumor cell killing | Full Text | References | PDF (1 MB) | Supplemental
  • 1405 Views
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Article
A novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice
Gabriela Maria Wiedemann, Severin Johannes Jacobi, Michael Chaloupka, Angelina Krächan, Svetlana Hamm, Stefan Strobl, Roland Baumgartner, Simon Rothenfusser, Peter Duewell, Stefan Endres & Sebastian Kobold
Article: e1189051
Published online: 11 Jul 2016
AbstractforA novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice | Full Text | References | PDF (887.3 KB) | Supplemental
  • 1958 Views
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Article
Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients
Steve Boudewijns, Kalijn F. Bol, Gerty Schreibelt, Harm Westdorp, Johannes C. Textor, Michelle M. van Rossum, Nicole M. Scharenborg, Annemiek J. de Boer, Mandy W. M. M. van de Rakt, Jeanne M. Pots, Tom G. M. van Oorschot, Tjitske Duiveman-de Boer, Michel A. Olde Nordkamp, Wilmy S. E. C. van Meeteren, Winette T. A. van der Graaf, Johannes J. Bonenkamp, Johannes H. W. de Wilt, Erik H. J. G. Aarntzen, Cornelis J. A. Punt, Winald R. Gerritsen, Carl G. Figdor & I. Jolanda M. de Vries
Article: e1191732
Published online: 11 Jul 2016
AbstractforAdjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients | Full Text | References | PDF (1 MB) | Supplemental
  • 1335 Views
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Article
Macrophages promote matrix protrusive and invasive function of breast cancer cells via MIP-1β dependent upregulation of MYO3A gene in breast cancer cells
Khemraj Singh Baghel, Brij Nath Tewari, Richa Shrivastava, Showkat Ahmad Malik, Mehraj U-Din Lone, Nem Kumar Jain, Chakrapani Tripathi, Ranjana Kumari Kanchan, Sameer Dixit, Kavita Singh, Kalyan Mitra, Mahendra Pal Singh Negi, Mukesh Srivastava, Sanjeev Misra, Madan Lal Brahma Bhatt & Smrati Bhadauria
Article: e1196299
Published online: 15 Jul 2016
AbstractforMacrophages promote matrix protrusive and invasive function of breast cancer cells via MIP-1β dependent upregulation of MYO3A gene in breast cancer cells | Full Text | References | PDF (2.7 MB) | Supplemental
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ORIGINAL RESEARCH

Article
Ipilimumab reshapes T cell memory subsets in melanoma patients with clinical response
Joana Felix, Jérome Lambert, Marie Roelens, Eve Maubec, Hélène Guermouche, Cécile Pages, Irina Sidina, Debora J. Cordeiro, Guitta Maki, François Chasset, Raphaël Porcher, Martine Bagot, Anne Caignard, Antoine Toubert, Céleste Lebbé & Hélène Moins-Teisserenc
Article: 1136045
Published online: 11 Jul 2016
AbstractforIpilimumab reshapes T cell memory subsets in melanoma patients with clinical response | Full Text | References | PDF (876 KB) | Supplemental
  • 1544 Views
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Review

Review
Current tools for predicting cancer-specific T cell immunity
David Gfeller, Michal Bassani-Sternberg, Julien Schmidt & Immanuel F. Luescher
Article: e1177691
Published online: 29 Jun 2016
AbstractforCurrent tools for predicting cancer-specific T cell immunity | Full Text | References | PDF (683.9 KB)
  • 3168 Views
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Review
Embracing rejection: Immunologic trends in brain metastasis
S. Harrison Farber, Vadim Tsvankin, Jessica L. Narloch, Grace J. Kim, April K. S. Salama, Gordana Vlahovic, Kimberly L. Blackwell, John P. Kirkpatrick & Peter E. Fecci
Article: e1172153
Published online: 29 Jun 2016
AbstractforEmbracing rejection: Immunologic trends in brain metastasis | Full Text | References | PDF (625.8 KB)
  • 1440 Views
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Review
The dual role of tumor lymphatic vessels in dissemination of metastases and immune response development
Joanna Stachura, Malgorzata Wachowska, Witold W. Kilarski, Esra Güç, Jakub Golab & Angelika Muchowicz
Article: e1182278
Published online: 30 Jun 2016
AbstractforThe dual role of tumor lymphatic vessels in dissemination of metastases and immune response development | Full Text | References | PDF (778.6 KB)
  • 2031 Views
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Review
Investigating potential exogenous tumor initiating and promoting factors for Cutaneous T-Cell Lymphomas (CTCL), a rare skin malignancy
Ivan V. Litvinov, Anna Shtreis, Kenneth Kobayashi, Steven Glassman, Matthew Tsang, Anders Woetmann, Denis Sasseville, Niels Ødum & Madeleine Duvic
Article: e1175799
Published online: 29 Jun 2016
AbstractforInvestigating potential exogenous tumor initiating and promoting factors for Cutaneous T-Cell Lymphomas (CTCL), a rare skin malignancy | Full Text | References | PDF (406.5 KB)
  • 1936 Views
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Review
Chemotherapy and immunotherapy: A close interplay to fight cancer?
Aurélie Hanoteau & Muriel Moser
Article: e1190061
Published online: 15 Jul 2016
AbstractforChemotherapy and immunotherapy: A close interplay to fight cancer? | Full Text | References | PDF (553.1 KB)
  • 1157 Views
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Review
Improving cancer immunotherapy by targeting the STATe of MDSCs
Nienke de Haas, Coco de Koning, Lisanne Spilgies, I. Jolanda M. de Vries & Stanleyson V. Hato
Article: e1196312
Published online: 27 Jun 2016
AbstractforImproving cancer immunotherapy by targeting the STATe of MDSCs | Full Text | References | PDF (1.1 MB)
  • 2585 Views
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