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OncoImmunology Volume 5, 2016 - Issue 12
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Original Research

T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy

Jon Amund KyteDepartment for Cell Therapy, Oslo University Hospital, Oslo, Norway;Department of Oncology, Oslo University Hospital, Oslo, Norway;Department of Haematology, UCL Cancer Institute, University College London, London, UKCorrespondence[email protected]
,
Gustav GaudernackDepartment for Immunology, Cancer Research Institute, Oslo University Hospital, Oslo, Norway;Faculty of Medicine, University of Oslo, Oslo, Norway
,
Anne FaaneDepartment for Cell Therapy, Oslo University Hospital, Oslo, Norway
,
Kari LislerudDepartment for Cell Therapy, Oslo University Hospital, Oslo, Norway
,
Else Marit InderbergDepartment for Cell Therapy, Oslo University Hospital, Oslo, Norway
,
Paal BrunsvigClinical Trial Unit, Department of Oncology, Oslo University Hospital, Oslo, Norway
,
Steinar AamdalFaculty of Medicine, University of Oslo, Oslo, Norway;Clinical Trial Unit, Department of Oncology, Oslo University Hospital, Oslo, Norway
,
Gunnar KvalheimDepartment for Cell Therapy, Oslo University Hospital, Oslo, Norway
,
Sébastien WälchliDepartment for Cell Therapy, Oslo University Hospital, Oslo, Norway;Department for Immunology, Cancer Research Institute, Oslo University Hospital, Oslo, Norway
&
Martin PuleDepartment of Haematology, UCL Cancer Institute, University College London, London, UK
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Article: e1249090 | Received 27 Jun 2016, Accepted 12 Oct 2016, Published online: 05 Dec 2016

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Jon Amund Kyte, Anne Fåne, Martin Pule & Gustav Gaudernack. (2019) Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination. OncoImmunology 8:4.
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Articles from other publishers (12)

Carole Beck, Nicholas Paul Casey, Irene Persiconi, Neda Nejati Moharrami, Adam Sike, Yixin Jin & Jon Amund Kyte. (2023) Development of a TGFβ—IL-2/15 Switch Receptor for Use in Adoptive Cell Therapy. Biomedicines 11:2, pages 459.
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Dimitrios Bafaloukos, Kalliopi Petraki, Aikaterini Bousmpoukea, Eleni Chatzichristou, Ioannis Pieris, Christos Koutserimpas & George Samonis. (2022) Therapeutic Effect of mRNA SARS-CoV-2 Vaccine on Melanoma Skin Metastases. Vaccines 10:4, pages 525.
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Jon Amund Kyte. (2022) Strategies for Improving the Efficacy of CAR T Cells in Solid Cancers. Cancers 14:3, pages 571.
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Anqi Lin, Hongman Zhang, Hui Meng, Ze Deng, Tianqi Gu, Peng Luo & Jian Zhang. (2021) TNF-Alpha Pathway Alternation Predicts Survival of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer. Frontiers in Immunology 12.
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Robert H Vonderheide, Kimberly A Kraynyak, Anthony F Shields, Autumn J McRee, Jennifer M Johnson, Weijing Sun, Ashish V Chintakuntlawar, Jan Pawlicki, Albert J Sylvester, Trevor McMullan, Robert Samuels, Joseph J Kim, David Weiner, Jean D Boyer, Matthew P Morrow, Laurent Humeau & Jeffrey M Skolnik. (2021) Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors. Journal for ImmunoTherapy of Cancer 9:7, pages e003019.
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Pierre Dillard, Hakan Köksal, Solrun Melkorka Maggadottir, Anna Winge-Main, Sylvie Pollmann, Mathilde Menard, Marit Renée Myhre, Gunhild M. Mælandsmo, Vivi Ann Flørenes, Gustav Gaudernack, Gunnar Kvalheim, Sébastien Wälchli & Else Marit Inderberg. (2021) Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy. Molecular Therapy 29:3, pages 1199-1213.
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Simone Negrini, Raffaele De Palma & Gilberto Filaci. (2020) Anti-Cancer Immunotherapies Targeting Telomerase. Cancers 12:8, pages 2260.
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Stina George Fernandes, Rebecca Dsouza, Gouri Pandya, Anuradha Kirtonia, Vinay Tergaonkar, Sook Y. Lee, Manoj Garg & Ekta Khattar. (2020) Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential. Cancers 12:7, pages 1901.
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Alan Chen Chen, Renhuan Xu, Tao Wang, Junping Wei, Xiao-Yi Yang, Cong-Xiao Liu, Gangjun Lei, Herbert Kim Lyerly, Teri Heiland & Zachary Conrad Hartman. (2020) HER2-LAMP vaccines effectively traffic to endolysosomal compartments and generate enhanced polyfunctional T cell responses that induce complete tumor regression. Journal for ImmunoTherapy of Cancer 8:1, pages e000258.
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Thomas W. Smith & Michael I. Nishimura. 2020. Current Immunotherapeutic Strategies in Cancer. Current Immunotherapeutic Strategies in Cancer 129 151 .
Eishiro Mizukoshi & Shuichi Kaneko. (2019) Telomerase-Targeted Cancer Immunotherapy. International Journal of Molecular Sciences 20:8, pages 1823.
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Patricia Mercier-LetondalChrystel MartonMarina DeschampsChristophe FerrandCharline VauchyClément ChenutAurélie BaguetOlivier AdotéviChristophe BorgJeanne GalaineYann Godet. (2018) Isolation and Characterization of an HLA-DRB1*04-Restricted HPV16-E7 T Cell Receptor for Cancer Immunotherapy. Human Gene Therapy 29:10, pages 1202-1212.
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