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Original Research

Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients

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Article: e1323618 | Received 03 Feb 2017, Accepted 21 Apr 2017, Published online: 20 Jun 2017

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Ernest Y. Lee & Rajan P. Kulkarni. (2019) Circulating biomarkers predictive of tumor response to cancer immunotherapy. Expert Review of Molecular Diagnostics 19:10, pages 895-904.
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Alejandro López-Soto, Segundo Gonzalez & Lorenzo Galluzzi. (2017) Soluble NKG2D ligands limit the efficacy of immune checkpoint blockade. OncoImmunology 6:10.
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Hansol Lee, Inês Pires Da Silva, Umaimainthan Palendira, Richard A. Scolyer, Georgina V. Long & James S. Wilmott. (2021) Targeting NK Cells to Enhance Melanoma Response to Immunotherapies. Cancers 13:6, pages 1363.
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Nguyen Hoang Viet, Nguyen Quang Trung, Le Thanh Dong, Ly Quoc Trung & J. Luis Espinoza. (2021) Genetic variants in NKG2D axis and susceptibility to Epstein–Barr virus-induced nasopharyngeal carcinoma. Journal of Cancer Research and Clinical Oncology 147:3, pages 713-723.
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G. Karakousis. (2019) Immune checkpoint blockade: an urgent call for biomarkers to help guide treatment. British Journal of Dermatology 182:5, pages 1085-1086.
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Alexandra Frazao, Louise Rethacker, Meriem Messaoudene, Marie-Françoise Avril, Antoine Toubert, Nicolas Dulphy & Anne Caignard. (2019) NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment. Frontiers in Immunology 10.
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Fausto Petrelli, Raffaele Ardito, Barbara Merelli, Veronica Lonati, Mary Cabiddu, Silvia Seghezzi, Sandro Barni & Antonio Ghidini. (2019) Prognostic and predictive role of elevated lactate dehydrogenase in patients with melanoma treated with immunotherapy and BRAF inhibitors: a systematic review and meta-analysis. Melanoma Research 29:1, pages 1-12.
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Sheila López-Cobo, Carmen Campos-Silva, Amanda Moyano, Myriam Oliveira-Rodríguez, Annette Paschen, María Yáñez-Mó, María Carmen Blanco-López & Mar Valés-Gómez. (2018) Immunoassays for scarce tumour-antigens in exosomes: detection of the human NKG2D-Ligand, MICA, in tetraspanin-containing nanovesicles from melanoma. Journal of Nanobiotechnology 16:1.
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Claire Lhuillier, Claire Vanpouille-Box, Lorenzo Galluzzi, Silvia Chiara Formenti & Sandra Demaria. (2018) Emerging biomarkers for the combination of radiotherapy and immune checkpoint blockers. Seminars in Cancer Biology 52, pages 125-134.
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Marie-Andrée Forget, Cara Haymaker, Kenneth R. Hess, Yuzhong Jeff Meng, Caitlin Creasy, Tatiana Karpinets, Orenthial J. Fulbright, Jason Roszik, Scott E. Woodman, Young Uk Kim, Donastas Sakellariou-Thompson, Ankit Bhatta, Arely Wahl, Esteban Flores, Shawne T. Thorsen, René J. Tavera, Renjith Ramachandran, Audrey M. Gonzalez, Christopher L. Toth, Seth Wardell, Rahmatu Mansaray, Vruti Patel, Destiny Joy Carpio, Carol Vaughn, Chantell M. Farinas, Portia G. Velasquez, Wen-Jen Hwu, Sapna P. Patel, Michael A. Davies, Adi Diab, Isabella C. Glitza, Hussein Tawbi, Michael K. Wong, Suzanne Cain, Merrick I. Ross, Jeffrey E. Lee, Jeffrey E. Gershenwald, Anthony Lucci, Richard Royal, Janice N. Cormier, Jennifer A. Wargo, Laszlo G. Radvanyi, Carlos A. Torres-Cabala, Rameen Beroukhim, Patrick Hwu, Rodabe N. Amaria & Chantale Bernatchez. (2018) Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome. Clinical Cancer Research 24:18, pages 4416-4428.
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Dominik Schmiedel & Ofer Mandelboim. (2018) NKG2D Ligands–Critical Targets for Cancer Immune Escape and Therapy. Frontiers in Immunology 9.
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Sam Sheppard, Amir Ferry, Joana Guedes & Nadia Guerra. (2018) The Paradoxical Role of NKG2D in Cancer Immunity. Frontiers in Immunology 9.
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Lorenzo Pilla & Cristina Maccalli. (2018) Immune Profiling of Cancer Patients Treated with Immunotherapy: Advances and Challenges. Biomedicines 6:3, pages 76.
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Kristina Buder-Bakhaya & Jessica C. Hassel. (2018) Biomarkers for Clinical Benefit of Immune Checkpoint Inhibitor Treatment—A Review From the Melanoma Perspective and Beyond. Frontiers in Immunology 9.
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Payal Dhar & Jennifer D Wu. (2018) NKG2D and its ligands in cancer. Current Opinion in Immunology 51, pages 55-61.
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