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OncoImmunology Volume 6, 2017 - Issue 7
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Original Research

Adjuvant immunotherapy with autologous dendritic cells for hepatocellular carcinoma, randomized phase II study

Jeong-Hoon LeeDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, KoreaORCID Iconhttp://orcid.org/0000-0002-0315-2080
ORCID Icon,
Won Young TakDepartment of Internal Medicine, Kyungpook National University School of Medicine, Daegu, KoreaORCID Iconhttp://orcid.org/0000-0002-1914-5141
ORCID Icon,
Yoon LeeDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea;JW CreaGene Research Institute, JW CreaGene Inc., Seongnam-si, Gyeonggi-do, KoreaORCID Iconhttp://orcid.org/0000-0002-4595-5367
ORCID Icon,
Min-Kyu HeoJW CreaGene Research Institute, JW CreaGene Inc., Seongnam-si, Gyeonggi-do, KoreaORCID Iconhttp://orcid.org/0000-0002-7836-0829
ORCID Icon,
Jae-Sung SongJW CreaGene Research Institute, JW CreaGene Inc., Seongnam-si, Gyeonggi-do, KoreaORCID Iconhttp://orcid.org/0000-0002-9108-7695
ORCID Icon,
Hak-Yeop KimJW CreaGene Research Institute, JW CreaGene Inc., Seongnam-si, Gyeonggi-do, KoreaORCID Iconhttp://orcid.org/0000-0002-7744-8386
ORCID Icon,
Soo Young ParkDepartment of Internal Medicine, Kyungpook National University School of Medicine, Daegu, KoreaORCID Iconhttp://orcid.org/0000-0002-4944-4396
ORCID Icon,
Si Hyun BaeThe Catholic University Liver Research Center, The Catholic University of Korea, Seoul, Korea
,
Joon Hyeok LeeSamsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
,
Jeong HeoDepartment of Internal Medicine, Pusan National University School of Medicine, Busan, Republic of KoreaORCID Iconhttp://orcid.org/0000-0003-0961-7851
ORCID Icon,
Ki-Hwan KimJW CreaGene Research Institute, JW CreaGene Inc., Seongnam-si, Gyeonggi-do, KoreaORCID Iconhttp://orcid.org/0000-0001-7219-8966
ORCID Icon,
Yong-Soo BaeDepartment of Biological Science, Sungkyunkwan University, Suwon, Korea;JW CreaGene Research Institute, JW CreaGene Inc., Seongnam-si, Gyeonggi-do, KoreaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-2233-9449
ORCID Icon &
Yoon Jun KimDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, KoreaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-9141-7773
ORCID Icon show all
Article: e1328335 | Received 10 Feb 2017, Accepted 05 May 2017, Published online: 28 Jun 2017

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Yinjie Fan, Hang Xue & Huachuan Zheng. (2022) Systemic Therapy for Hepatocellular Carcinoma: Current Updates and Outlook. Journal of Hepatocellular Carcinoma 9, pages 233-263.
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Jenny Sprooten, Jolien Ceusters, An Coosemans, Patrizia Agostinis, Steven De Vleeschouwer, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi & Abhishek D. Garg. (2019) Trial watch: dendritic cell vaccination for cancer immunotherapy. OncoImmunology 8:11.
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Wei Zhang, Bixiang Zhang & Xiao-ping Chen. (2021) Adjuvant treatment strategy after curative resection for hepatocellular carcinoma. Frontiers of Medicine 15:2, pages 155-169.
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Han Xiao, Ben Wang, Hai‐Xia Xiong, Jia‐Fu Guan, Jian Wang, Tao Tan, Kang Lin, Shu‐Bing Zou, Zhi‐Gang Hu & Kai Wang. (2020) A novel prognostic index of hepatocellular carcinoma based on immunogenomic landscape analysis. Journal of Cellular Physiology 236:4, pages 2572-2591.
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Xiao-Dong Zhu, Kang-Shuai Li & Hui-Chuan Sun. (2020) Adjuvant therapies after curative treatments for hepatocellular carcinoma: Current status and prospects. Genes & Diseases 7:3, pages 359-369.
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Muhammad Tarek Abdel Ghafar, Morad Ahmed Morad, Enas A. El-Zamarany, Dina Ziada, Hanan Soliman, Sherief Abd-Elsalam & Marwa Salama. (2020) Autologous dendritic cells pulsed with lysate from an allogeneic hepatic cancer cell line as a treatment for patients with advanced hepatocellular carcinoma: A pilot study. International Immunopharmacology 82, pages 106375.
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David Prince, Ken Liu, Weiqi Xu, Minjiang Chen, Jin-Yu Sun, Xiao-Jie Lu & Jiansong Ji. (2020) Management of patients with intermediate stage hepatocellular carcinoma. Therapeutic Advances in Medical Oncology 12, pages 175883592097084.
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Eishiro Mizukoshi & Shuichi Kaneko. (2019) Immune cell therapy for hepatocellular carcinoma. Journal of Hematology & Oncology 12:1.
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Jing Cao, Fan-Hua Kong, Xi Liu & Xiao-Bo Wang. (2019) Immunotherapy with dendritic cells and cytokine-induced killer cells for hepatocellular carcinoma: A meta-analysis. World Journal of Gastroenterology 25:27, pages 3649-3663.
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Yuri Cho, Jimin Han & Won Kim. (2019) Recent Advances and Future Directions in Immunotherapeutics for Hepatocellular Carcinoma. Journal of Liver Cancer 19:1, pages 1-11.
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Anne Huber, Floris Dammeijer, Joachim G. J. V. Aerts & Heleen Vroman. (2018) Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?. Frontiers in Immunology 9.
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Naofumi Mukaida & Yasunari Nakamoto. (2018) Emergence of immunotherapy as a novel way to treat hepatocellular carcinoma. World Journal of Gastroenterology 24:17, pages 1839-1858.
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Jeong-Hoon Lee & Jung-Hwan Yoon. 2017. Immunotherapy of Hepatocellular Carcinoma. Immunotherapy of Hepatocellular Carcinoma 69 84 .

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