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OncoImmunology Volume 7, 2018 - Issue 2
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Original Research

High numbers of PDCD1 (PD-1)-positive T cells and B2M mutations in microsatellite-unstable colorectal cancer

Jonas JanikovitsDepartment of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL Heidelberg
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Meike MüllerDepartment of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL Heidelberg
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Julia KrzykallaDivision of Biostatistics, DKFZ (German Cancer Research Center), Heidelberg, Germany
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Sandrina KörnerDepartment of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL Heidelberg
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Fabian EchterdiekDepartment of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL Heidelberg
,
Bernd LahrmannHamamatsu Tissue Imaging and Analysis (TIGA) Center, Heidelberg, Germany
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Niels GrabeHamamatsu Tissue Imaging and Analysis (TIGA) Center, Heidelberg, Germany
,
Martin SchneiderDepartment of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
,
Axel BennerDivision of Biostatistics, DKFZ (German Cancer Research Center), Heidelberg, Germany
,
Magnus von Knebel DoeberitzDepartment of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL HeidelbergORCID Iconhttps://orcid.org/0000-0002-0498-6781
ORCID Icon &
Matthias KloorDepartment of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL HeidelbergCorrespondence[email protected]
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Article: e1390640 | Received 30 Jun 2017, Accepted 05 Oct 2017, Published online: 06 Nov 2017

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Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi & Abhishek D. Garg. (2020) Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology. OncoImmunology 9:1.
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Mine Ozcan, Jonas Janikovits, Magnus von Knebel Doeberitz & Matthias Kloor. (2018) Complex pattern of immune evasion in MSI colorectal cancer. OncoImmunology 7:7.
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