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OncoImmunology Volume 7, 2018 - Issue 8
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Original Research

Microvesicles released from multiple myeloma cells are equipped with ectoenzymes belonging to canonical and non-canonical adenosinergic pathways and produce adenosine from ATP and NAD+

F. MorandiStem Cell Laboratory and Cell Therapy Center, Istituto Giannina Gaslini, Genova, ItalyCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-2849-7595 http://orcid.org/0000-0002-2849-7595View further author information
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D. MarimpietriStem Cell Laboratory and Cell Therapy Center, Istituto Giannina Gaslini, Genova, ItalyORCID Iconhttp://orcid.org/0000-0001-6360-1661View further author information
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A. L. HorensteinLaboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, Italy;CeRMS, University of Torino, Torino, ItalyORCID Iconhttp://orcid.org/0000-0002-0382-0595View further author information
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M. BolzoniDepartment of Medicine and Surgery, University of Parma, Parma, ItalyORCID Iconhttp://orcid.org/0000-0002-0821-8093View further author information
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D. ToscaniDepartment of Medicine and Surgery, University of Parma, Parma, ItalyORCID Iconhttp://orcid.org/0000-0003-3492-4415View further author information
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F. CostaDepartment of Medicine and Surgery, University of Parma, Parma, ItalyORCID Iconhttp://orcid.org/0000-0002-1742-9212View further author information
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B. CastellaLaboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, ItalyORCID Iconhttp://orcid.org/0000-0002-5880-2263View further author information
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A. C. FainiLaboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, ItalyORCID Iconhttp://orcid.org/0000-0003-2193-4577View further author information
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M. MassaiaCeRMS, University of Torino, Torino, Italy;SC Ematologia AO S. Croce Carle, Cuneo, ItalyORCID Iconhttp://orcid.org/0000-0002-0021-1428View further author information
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V. PistoiaImmunology Area, Pediatric Hospital Bambino Gesù, Rome, ItalyORCID Iconhttp://orcid.org/0000-0003-0528-9563View further author information
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N. GiulianiDepartment of Medicine and Surgery, University of Parma, Parma, ItalyORCID Iconhttp://orcid.org/0000-0003-3457-3774View further author information
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F. MalavasiLaboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, Italy;CeRMS, University of Torino, Torino, ItalyORCID Iconhttp://orcid.org/0000-0002-1844-174XView further author information
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Article: e1458809 | Received 17 Jan 2018, Accepted 26 Mar 2018, Published online: 07 May 2018

Citations (4)

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Read on this site (3)

Fabio Morandi, Danilo Marimpietri, Alberto L. Horenstein, Maria Valeria Corrias & Fabio Malavasi. (2019) Microvesicles expressing adenosinergic ectoenzymes and their potential role in modulating bone marrow infiltration by neuroblastoma cells. OncoImmunology 8:5.
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Luciana De Luca, Ilaria Laurenzana, Stefania Trino, Daniela Lamorte, Antonella Caivano & Pellegrino Musto. (2019) An update on extracellular vesicles in multiple myeloma: a focus on their role in cell-to-cell cross-talk and as potential liquid biopsy biomarkers. Expert Review of Molecular Diagnostics 19:3, pages 249-258.
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Jayeeta Ghose, Domenico Viola, Cesar Terrazas, Enrico Caserta, Estelle Troadec, Jihane Khalife, Emine Gulsen Gunes, James Sanchez, Tinisha McDonald, Guido Marcucci, Balveen Kaur, Michael Rosenzweig, Jonathan Keats, Steven Rosen, Amrita Krishnan, Abhay R Satoskar, Craig C Hofmeister & Flavia Pichiorri. (2018) Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. OncoImmunology 7:10.
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Articles from other publishers (1)

David Allard, Pavel Chrobak, Bertrand Allard, Nouredin Messaoudi & John Stagg. (2019) Targeting the CD73-adenosine axis in immuno-oncology. Immunology Letters 205, pages 31-39.
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