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OncoImmunology Volume 8, 2019 - Issue 2
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Original Research

Immunological differences between colorectal cancer and normal mucosa uncover a prognostically relevant immune cell profile

Katharina StrasserDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria;CBmed GmbH – Center for Biomarker Research in Medicine, Graz, AustriaORCID Iconhttp://orcid.org/0000-0001-6962-5285View further author information
ORCID Icon,
Hanna BirnleitnerDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0002-5009-5656View further author information
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Andrea BeerDepartment of Pathology, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0002-0726-1233View further author information
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Dietmar PilsDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria;Center for Medical Statistics, Informatics and Intelligent Systems, Section for Clinical Biometrics, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0002-8355-0977View further author information
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Marlene C. GernerDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0002-4378-9254View further author information
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Klaus G. SchmettererDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0001-9328-4871View further author information
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Thomas Bachleitner-HofmannDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0002-4201-8247View further author information
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Anton StiftDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0002-7243-8138View further author information
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Michael BergmannDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, AustriaORCID Iconhttp://orcid.org/0000-0001-8529-1166View further author information
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Rudolf OehlerDepartment of Surgery and Comprehensive Cancer Center, Medical University of Vienna, Vienna, AustriaCorrespondence[email protected]; [email protected]
ORCID Iconhttp://orcid.org/0000-0003-2891-7155View further author information
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Article: e1537693 | Received 24 Jun 2018, Accepted 10 Oct 2018, Published online: 05 Nov 2018

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Song Van Nguyen, Levar Shamoun, Kalle Landerholm, Dick Wågsäter & Jan Dimberg. (2023) Clinicopathological and prognostic value of CD44 gene polymorphism (rs187115) in Swedish patients with colorectal cancer. Nucleosides, Nucleotides & Nucleic Acids 42:10, pages 807-817.
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Wenjie Sun, Qingrong Sun, Anjing Zhong, Anne-Marie Lyne, Dongdong Huang, Fengyan Han, Maode Lai & Honghe Zhang. (2022) TP53 mutation is enriched in colorectal cancer liver metastasis in the context of polyclonal seeding. Pathology - Research and Practice 236, pages 153958.
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Natalie Walterskirchen, Catharina Müller, Cristiano Ramos, Stephan Zeindl, Simone Stang, Daniela Herzog, Monika Sachet, Vanessa Schimek, Lukas Unger, Vasileios Gerakopoulos, Markus Hengstschläger, Thomas Bachleitner-Hofmann, Michael Bergmann, Helmut Dolznig & Rudolf Oehler. (2022) Metastatic colorectal carcinoma-associated fibroblasts have immunosuppressive properties related to increased IGFBP2 expression. Cancer Letters 540, pages 215737.
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William Jayasekara Kothalawala & Balázs Győrffy. (2022) Transcriptomic and cellular content analysis of colorectal cancer by combining multiple independent cohorts. Clinical and Translational Gastroenterology Publish Ahead of Print.
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YaChen Wang, Luping Zhang, Guanghuan Shi, Mingqing Liu, Weidan Zhao, Yingli Zhang, Ying Wang & Nan Zhang. (2022) Effects of Inflammatory Response Genes on the Immune Microenvironment in Colorectal Cancer. Frontiers in Genetics 13.
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Vanessa Schimek, Katharina Strasser, Andrea Beer, Samantha Göber, Natalie Walterskirchen, Christine Brostjan, Catharina Müller, Thomas Bachleitner-Hofmann, Michael Bergmann, Helmut Dolznig & Rudolf Oehler. (2022) Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment. Cell Death & Disease 13:2.
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Qi Zou, Xiaolin Wang, Donglin Ren, Bang Hu, Guannan Tang, Yu Zhang, Meijin Huang, Rish K Pai, Daniel D Buchanan, Aung Ko Win, Polly A Newcomb, William M Grady, Huichuan Yu & Yanxin Luo. (2021) DNA methylation-based signature of CD8+ tumor-infiltrating lymphocytes enables evaluation of immune response and prognosis in colorectal cancer. Journal for ImmunoTherapy of Cancer 9:9, pages e002671.
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