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Jiayan Lou, Lingjia Wei & He Wang. (2022) SCNN1A Overexpression Correlates with Poor Prognosis and Immune Infiltrates in Ovarian Cancer. International Journal of General Medicine 15, pages 1743-1763.
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Cecilia Pesini, Sandra Hidalgo, Maykel A. Arias, Llipsy Santiago, Carlota Calvo, Maitane Ocariz-Díez, Dolores Isla, Pilar M. Lanuza, M José Agustín, Eva M Galvez, Ariel Ramírez-Labrada & Julián Pardo. (2022) PD-1 is expressed in cytotoxic granules of NK cells and rapidly mobilized to the cell membrane following recognition of tumor cells. OncoImmunology 11:1.
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Francesca Romana Mariotti, Tiziano Ingegnere, Nadine Landolina, Paola Vacca, Enrico Munari & Lorenzo Moretta. (2023) Analysis of the mechanisms regulating soluble PD-1 production and function in human NK cells. Frontiers in Immunology 14.
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Sanja TripkovićMiodrag Jocić, Isidora Stanisavljević, Marina Jovanović, Milena Jurišević, Andjela Petrović, Milan Jovanović, Boško Milev, Veljko Marić & Marina Jovanović. (2023) PD-1 Blockage Facilitates Cytotoxic T and NK Cells Tumoricidal Phenotype in a Murine Breast Carcinoma. Experimental and Applied Biomedical Research (EABR) 0:0.
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Darren Chen Pei Wong, Zekun Xia, Nandi Shao, Ivan Yow, T. Thivakar, Jin Ye Yeo, Andres M. Salazar, Yih‐Cherng Liou, Boon Chuan Low & Jeak Ling Ding. (2023) Hiltonol, a dsRNA Mimic, Promotes NK Cell Anticancer Cytotoxicity Through TAZ Cytoplasmic Sequestration. Advanced Therapeutics 6:8.
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Marco Greppi, Valentina Obino, Rayan Goda, Federico Rebaudi, Simona Carlomagno, Mariella Della Chiesa, Simona Sivori, Gianluca Ubezio, Vanessa Agostini, Alessandra Bo, Silvia Pesce & Emanuela Marcenaro. (2023) Identification of a novel cord blood NK cell subpopulation expressing functional programmed death receptor-1. Frontiers in Immunology 14.
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Sabina Di Matteo, Enrico Munari, Piera Filomena Fiore, Silvia Santopolo, Camilla Sampaoli, Andrea Pelosi, Salem Chouaib, Nicola Tumino, Paola Vacca, Francesca Romana Mariotti, Stefan Ebert, Markus Machwirth, Dorothee Haas, Marco Pezzullo, Gabriella Pietra, Melania Grottoli, Stephanie Buart, Erwan Mortier, Enrico Maggi, Lorenzo Moretta, Ignazio Caruana & Bruno Azzarone. (2023) The roles of different forms of IL-15 in human melanoma progression. Frontiers in Immunology 14.
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Tannaz Dehghani, Alireza Shahrjerdi, Mohammad Saeed Kahrizi, Elnaz Soleimani, Saeideh Ravandeh, Muna S. Merza, Negin Rahnama, Farnoosh Ebrahimzadeh & Morteza Bakhshesh. (2023) Targeting programmed cell death protein 1 (PD-1) for treatment of non-small-cell lung carcinoma (NSCLC); the recent advances. Pathology - Research and Practice 246, pages 154470.
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Lucile Dumolard, Caroline Aspord, Patrice N. Marche & Zuzana Macek Jilkova. (2023) Immune checkpoints on T and NK cells in the context of HBV infection: Landscape, pathophysiology and therapeutic exploitation. Frontiers in Immunology 14.
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Nicoletta Provinciali, Marco Greppi, Silvia Pesce, Mariangela Rutigliani, Irene Maria Briata, Tania Buttiron Webber, Marianna Fava, Andrea DeCensi & Emanuela Marcenaro. (2022) Case report: Variable response to immunotherapy in ovarian cancer: Our experience within the current state of the art. Frontiers in Immunology 13.
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Maryam Bahmanyar, Mohammad Kazem Vakil, Ghaidaa Raheem Lateef Al-Awsi, Seyed Amin Kouhpayeh, Yaser Mansoori, Behnam Mansoori, Ali Moravej, Abdulbaset Mazarzaei & Abdolmajid Ghasemian. (2022) Anticancer traits of chimeric antigen receptors (CARs)-Natural Killer (NK) cells as novel approaches for melanoma treatment. BMC Cancer 22:1.
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Sasitorn Yenyuwadee, Konstantinos Aliazis, Qi Wang, Anthos Christofides, Rushil Shah, Nikolaos Patsoukis & Vassiliki A. Boussiotis. (2022) Immune cellular components and signaling pathways in the tumor microenvironment. Seminars in Cancer Biology 86, pages 187-201.
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Anup S. Pathania, Philip Prathipati, Swati P. Murakonda, Ajay B. Murakonda, Ankit Srivastava, Avadhesh, Siddappa N. Byrareddy, Don W. Coulter, Subash C. Gupta & Kishore B. Challagundla. (2022) Immune checkpoint molecules in neuroblastoma: A clinical perspective. Seminars in Cancer Biology 86, pages 247-258.
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Stephanie Laba, Grace Mallett & Shoba Amarnath. (2022) The depths of PD-1 function within the tumor microenvironment beyond CD8+ T cells. Seminars in Cancer Biology 86, pages 1045-1055.
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Nicholas A. Maskalenko, Dmitry Zhigarev & Kerry S. Campbell. (2022) Harnessing natural killer cells for cancer immunotherapy: dispatching the first responders. Nature Reviews Drug Discovery 21:8, pages 559-577.
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Shweta Joshi & Andrew Sharabi. (2022) Targeting myeloid-derived suppressor cells to enhance natural killer cell-based immunotherapy. Pharmacology & Therapeutics 235, pages 108114.
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Maria-Luisa del Rio, Jose-Antonio Perez-Simon & Jose-Ignacio Rodriguez-Barbosa. (2022) Differential Engraftment of Parental A20 PD-L1 WT and PD-L1 KO Leukemia Cells in Semiallogeneic Recipients in the Context of PD-L1/PD-1 Interaction and NK Cell-Mediated Hybrid Resistance. Frontiers in Immunology 13.
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Anup S. Pathania, Philip Prathipati, Omalla A. Olwenyi, Srinivas Chava, Oghenetejiri V. Smith, Subash C. Gupta, Nagendra K. Chaturvedi, Siddappa N. Byrareddy, Don W. Coulter & Kishore B. Challagundla. (2022) miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma. Molecular Therapy - Oncolytics 25, pages 308-329.
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Rilan Bai & Jiuwei Cui. (2022) Burgeoning Exploration of the Role of Natural Killer Cells in Anti-PD-1/PD-L1 Therapy. Frontiers in Immunology 13.
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Yutao Li, Amit Sharma, Xiaolong Wu, Hans Weiher, Dirk Skowasch, Markus Essler & Ingo G. H. Schmidt-Wolf. (2022) A Combination of Cytokine-Induced Killer Cells With PD-1 Blockade and ALK Inhibitor Showed Substantial Intrinsic Variability Across Non-Small Cell Lung Cancer Cell Lines. Frontiers in Oncology 12.
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Nadine Landolina, Francesca Romana Mariotti, Tiziano Ingegnere, Claudia Alicata, Biancamaria Ricci, Andrea Pelosi, Irene Veneziani, Bruno Giuseppe Azzarone, Cecilia Garlanda, Alberto Mantovani, Lorenzo Moretta & Enrico Maggi. (2022) IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells. Journal for ImmunoTherapy of Cancer 10:3, pages e003858.
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Emily F. Davis-Marcisak, Allison A. Fitzgerald, Michael D. Kessler, Ludmila Danilova, Elizabeth M. Jaffee, Neeha Zaidi, Louis M. Weiner & Elana J. Fertig. (2021) Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors. Genome Medicine 13:1.
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Fehim Esen, Günnur Deniz & Esin Cetin Aktas. (2021) PD-1, CTLA-4, LAG-3, and TIGIT: The roles of immune checkpoint receptors on the regulation of human NK cell phenotype and functions. Immunology Letters 240, pages 15-23.
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Ana Vuletić, Katarina Mirjačić Martinović, Nevena Tišma Miletić, Jerome Zoidakis, Sergi Castellvi-Bel & Milena Čavić. (2021) Cross-Talk Between Tumor Cells Undergoing Epithelial to Mesenchymal Transition and Natural Killer Cells in Tumor Microenvironment in Colorectal Cancer. Frontiers in Cell and Developmental Biology 9.
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Kristian W. Antonsen, Claus V.B. Hviid, Mette K. Hagensen, Boe S. Sørensen & Holger J. Møller. (2021) Soluble PD-1 (sPD-1) is expressed in human macrophages. Cellular Immunology 369, pages 104435.
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Karolina Bednarska, Karthik Nath, William Nicol & Maher K. Gandhi. (2021) Immunity reloaded: Deconstruction of the PD-1 axis in B cell lymphomas. Blood Reviews 50, pages 100832.
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Nadia Mensali, Pierre Dillard, Artem Fayzullin, Hakan Köksal, Gustav Gaudernack, Gunnar Kvalheim, Else Marit Inderberg & Sébastien Wälchli. (2021) “Built‐in” PD‐1 blocker to rescue NK‐92 activity from PD‐L1–mediated tumor escape mechanisms. The FASEB Journal 35:9.
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Shee Kwan Phung, Jeffrey S. Miller & Martin Felices. (2021) Bi-specific and Tri-specific NK Cell Engagers: The New Avenue of Targeted NK Cell Immunotherapy. Molecular Diagnosis & Therapy 25:5, pages 577-592.
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Irina Buckle & Camille Guillerey. (2021) Inhibitory Receptors and Immune Checkpoints Regulating Natural Killer Cell Responses to Cancer. Cancers 13:17, pages 4263.
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Haipeng Zhu & Xiaojun Liu. (2021) Advances of Tumorigenesis, Diagnosis at Early Stage, and Cellular Immunotherapy in Gastrointestinal Malignancies. Frontiers in Oncology 11.
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Elisa Zaghi, Michela Calvi, Simone Puccio, Gianmarco Spata, Sara Terzoli, Clelia Peano, Alessandra Roberto, Federica De Paoli, Jasper J.P. van Beek, Jacopo Mariotti, Chiara De Philippis, Barbara Sarina, Rossana Mineri, Stefania Bramanti, Armando Santoro, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Emanuela Marcenaro, Luca Castagna, Clara Di Vito, Enrico Lugli & Domenico Mavilio. (2021) Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT. JCI Insight 6:12.
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Darawan Rinchai, Elena Verzoni, Veronica Huber, Agata Cova, Paola Squarcina, Loris De Cecco, Filippo Braud, Raffaele Ratta, Matteo Dugo, Luca Lalli, Viviana Vallacchi, Monica Rodolfo, Jessica Roelands, Chiara Castelli, Damien Chaussabel, Giuseppe Procopio, Davide Bedognetti & Licia Rivoltini. (2021) Integrated transcriptional‐phenotypic analysis captures systemic immunomodulation following antiangiogenic therapy in renal cell carcinoma patients. Clinical and Translational Medicine 11:6.
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Hansol Lee, Inês Pires Da Silva, Umaimainthan Palendira, Richard A. Scolyer, Georgina V. Long & James S. Wilmott. (2021) Targeting NK Cells to Enhance Melanoma Response to Immunotherapies. Cancers 13:6, pages 1363.
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Veronica Olivo Pimentel, Damiënne Marcus, Alexander MA van der Wiel, Natasja G Lieuwes, Rianne Biemans, Relinde IY Lieverse, Dario Neri, Jan Theys, Ala Yaromina, Ludwig J Dubois & Philippe Lambin. (2021) Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy. Journal for ImmunoTherapy of Cancer 9:3, pages e001764.
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Johanna Bödder, Tasmin Zahan, Rianne van Slooten, Gerty Schreibelt, I. Jolanda M. de Vries & Georgina Flórez-Grau. (2021) Harnessing the cDC1-NK Cross-Talk in the Tumor Microenvironment to Battle Cancer. Frontiers in Immunology 11.
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Nicola Tumino, Anna Laura Di Pace, Francesca Besi, Linda Quatrini, Paola Vacca & Lorenzo Moretta. (2021) Interaction Between MDSC and NK Cells in Solid and Hematological Malignancies: Impact on HSCT. Frontiers in Immunology 12.
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Mahmoud S. Hanafy, Stephanie Hufnagel, Andrea N. Trementozzi, Wedad Sakran, Jeanne C. Stachowiak, John J. Koleng & Zhengrong Cui. (2021) PD-1 siRNA-Encapsulated Solid Lipid Nanoparticles Downregulate PD-1 Expression by Macrophages and Inhibit Tumor Growth. AAPS PharmSciTech 22:2.
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Linda Quatrini, Paola Vacca, Nicola Tumino, Francesca Besi, Anna Laura Di Pace, Francesca Scordamaglia, Stefania Martini, Enrico Munari, Maria Cristina Mingari, Sophie Ugolini & Lorenzo Moretta. (2021) Glucocorticoids and the cytokines IL-12, IL-15, and IL-18 present in the tumor microenvironment induce PD-1 expression on human natural killer cells. Journal of Allergy and Clinical Immunology 147:1, pages 349-360.
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Joanna Domagala, Mieszko Lachota, Marta Klopotowska, Agnieszka Graczyk-Jarzynka, Antoni Domagala, Andriy Zhylko, Karolina Soroczynska & Magdalena Winiarska. (2020) The Tumor Microenvironment—A Metabolic Obstacle to NK Cells’ Activity. Cancers 12:12, pages 3542.
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Silvia Pesce, Sara Trabanelli, Clara Di Vito, Marco Greppi, Valentina Obino, Fabio Guolo, Paola Minetto, Matteo Bozzo, Michela Calvi, Elisa Zaghi, Simona Candiani, Roberto Massimo Lemoli, Camilla Jandus, Domenico Mavilio & Emanuela Marcenaro. (2020) Cancer Immunotherapy by Blocking Immune Checkpoints on Innate Lymphocytes. Cancers 12:12, pages 3504.
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Linda Quatrini, Francesca Romana Mariotti, Enrico Munari, Nicola Tumino, Paola Vacca & Lorenzo Moretta. (2020) The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy. Cancers 12:11, pages 3285.
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Kaijian Zhou, Shu Guo, Fei Li, Qiang Sun & Guoxin Liang. (2020) Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies. Frontiers in Cell and Developmental Biology 8.
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Aimee M Merino, Hansol Kim, Jeffrey S. Miller & Frank Cichocki. (2020) Unraveling exhaustion in adaptive and conventional NK cells. Journal of Leukocyte Biology 108:4, pages 1361-1368.
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Simona Sivori, Mariella Della Chiesa, Simona Carlomagno, Linda Quatrini, Enrico Munari, Paola Vacca, Nicola Tumino, Francesca Romana Mariotti, Maria Cristina Mingari, Daniela Pende & Lorenzo Moretta. (2020) Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer. Frontiers in Immunology 11.
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Sachin Kumar Singh Chauhan, Ulrike Koehl & Stephan Kloess. (2020) Harnessing NK Cell Checkpoint-Modulating Immunotherapies. Cancers 12:7, pages 1807.
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F.R. Mariotti, L. Quatrini, E. Munari, P. Vacca, N. Tumino, G. Pietra, M.C. Mingari & L. Moretta. (2020) Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28. British Journal of Pharmacology 177:13, pages 2889-2903.
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Monica M. Cho, Aicha E. Quamine, Mallery R. Olsen & Christian M. Capitini. (2020) Programmed cell death protein 1 on natural killer cells: fact or fiction?. Journal of Clinical Investigation 130:6, pages 2816-2819.
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Sean J. Judge, Cordelia Dunai, Ethan G. Aguilar, Sarah C. Vick, Ian R. Sturgill, Lam T. Khuat, Kevin M. Stoffel, Jonathan Van Dyke, Dan L. Longo, Morgan A. Darrow, Stephen K. Anderson, Bruce R. Blazar, Arta M. Monjazeb, Jonathan S. Serody, Robert J. Canter & William J. Murphy. (2020) Minimal PD-1 expression in mouse and human NK cells under diverse conditions. Journal of Clinical Investigation 130:6, pages 3051-3068.
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Yuting Jiang, Chengdi Wang & Shengtao Zhou. (2020) Targeting tumor microenvironment in ovarian cancer: Premise and promise. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1873:2, pages 188361.
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Anna Di Pace, Nicola Tumino, Francesca Besi, Claudia Alicata, Libenzio Conti, Enrico Munari, Enrico Maggi, Paola Vacca & Lorenzo Moretta. (2020) Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor in Exosome-Mediated Cytotoxicity against Tumor. Cancers 12:3, pages 661.
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Silvia Pesce, Marco Greppi, Elisa Ferretti, Valentina Obino, Simona Carlomagno, Mariangela Rutigliani, Fredrik B. Thoren, Simona Sivori, Patrizio Castagnola, Simona Candiani & Emanuela Marcenaro. (2020) miRNAs in NK Cell-Based Immune Responses and Cancer Immunotherapy. Frontiers in Cell and Developmental Biology 8.
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Aviad Ben-Shmuel, Guy Biber & Mira Barda-Saad. (2020) Unleashing Natural Killer Cells in the Tumor Microenvironment–The Next Generation of Immunotherapy?. Frontiers in Immunology 11.
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Muhammad Khan, Sumbal Arooj & Hua Wang. (2020) NK Cell-Based Immune Checkpoint Inhibition. Frontiers in Immunology 11.
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Maite Alvarez, Federico Simonetta, Jeanette Baker, Alyssa R. Morrison, Arielle S. Wenokur, Antonio Pierini, Pedro Berraondo & Robert S. Negrin. (2020) Indirect Impact of PD-1/PD-L1 Blockade on a Murine Model of NK Cell Exhaustion. Frontiers in Immunology 11.
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Nicola Tumino, Paola Vacca, Linda Quatrini, Enrico Munari, Francesca Moretta, Andrea Pelosi, Francesca Romana Mariotti & Lorenzo Moretta. (2020) Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?. Frontiers in Immunology 10.
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Paola Vacca, Gabriella Pietra, Nicola Tumino, Enrico Munari, Maria Cristina Mingari & Lorenzo Moretta. (2020) Exploiting Human NK Cells in Tumor Therapy. Frontiers in Immunology 10.
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Pilar M. Lanuza, Cecilia Pesini, Maykel A. Arias, Carlota Calvo, Ariel Ramirez-Labrada & Julian Pardo. (2020) Recalling the Biological Significance of Immune Checkpoints on NK Cells: A Chance to Overcome LAG3, PD1, and CTLA4 Inhibitory Pathways by Adoptive NK Cell Transfer?. Frontiers in Immunology 10.
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Paola Fisicaro, Marzia Rossi, Andrea Vecchi, Greta Acerbi, Valeria Barili, Diletta Laccabue, Ilaria Montali, Alessandra Zecca, Amalia Penna, Gabriele Missale, Carlo Ferrari & Carolina Boni. (2019) The Good and the Bad of Natural Killer Cells in Virus Control: Perspective for Anti-HBV Therapy. International Journal of Molecular Sciences 20:20, pages 5080.
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Emilio Sanseviero. (2019) NK Cell-Fc Receptors Advance Tumor Immunotherapy. Journal of Clinical Medicine 8:10, pages 1667.
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Jonathan J. Hodgins, Sarwat T. Khan, Maria M. Park, Rebecca C. Auer & Michele Ardolino. (2019) Killers 2.0: NK cell therapies at the forefront of cancer control. Journal of Clinical Investigation 129:9, pages 3499-3510.
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Silvia Pesce, Valerio Belgrano, Marco Greppi, Simona Carlomagno, Margherita Squillario, Annalisa Barla, Mariella Della Chiesa, Stefano Di Domenico, Domenico Mavilio, Lorenzo Moretta, Simona Candiani, Simona Sivori, Franco De Cian & Emanuela Marcenaro. (2019) Different Features of Tumor-Associated NK Cells in Patients With Low-Grade or High-Grade Peritoneal Carcinomatosis. Frontiers in Immunology 10.
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Silvia Pesce, Marco Greppi, Francesco Grossi, Genny Del Zotto, Lorenzo Moretta, Simona Sivori, Carlo Genova & Emanuela Marcenaro. (2019) PD/1-PD-Ls Checkpoint: Insight on the Potential Role of NK Cells. Frontiers in Immunology 10.
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Francesca Romana Mariotti, Linda Quatrini, Enrico Munari, Paola Vacca & Lorenzo Moretta. (2019) Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions. Frontiers in Immunology 10.
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Michela Falco, Daniela Pende, Enrico Munari, Paola Vacca, Maria C. Mingari & Lorenzo Moretta. (2019) Natural killer cells: From surface receptors to the cure of high‐risk leukemia (Ceppellini Lecture). HLA 93:4, pages 185-194.
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