OncoImmunology, Volume 8, Issue 3 (2019)

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OncoImmunology, Volume 8, Issue 3 (2019)

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Brief Report

Brief Report
PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression
Francesca R. Mariotti, Stefania Petrini, Tiziano Ingegnere, Nicola Tumino, Francesca Besi, Francesca Scordamaglia, Enrico Munari, Silvia Pesce, Emanuela Marcenaro, Alessandro Moretta, Paola Vacca & Lorenzo Moretta
Article: 1557030
Published online: 25 Dec 2018
AbstractforPD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
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Commentary

Article Commentary
Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)
Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Meijing Wu, Denise M. Scholtens, Rohan Savoor, Bin Zhang, Jennifer D. Wu, Craig Horbinski, Rimas V. Lukas, David C. Binder & Derek A. Wainwright
Article: 1548242
Published online: 13 Dec 2018
AbstractforCommentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017) | Full Text | References | PDF (1.1 MB) | EPUB
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Original Research

Article
APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy
Amélie Boichard, Timothy V. Pham, Huwate Yeerna, Aaron Goodman, Pablo Tamayo, Scott Lippman, Garrett M. Frampton, Igor F. Tsigelny & Razelle Kurzrock
Article: 1550341
Published online: 24 Dec 2018
AbstractforAPOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 3071 Views
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Article
Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells
Ahdab Alsaieedi, Angelika Holler, Pedro Velica, Gavin Bendle & Hans J. Stauss
Article: 1542917
Published online: 05 Dec 2018
AbstractforSafety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 3260 Views
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Article
Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer
Ann Hanna, Brandon J. Metge, Sarah K. Bailey, Dongquan Chen, Darshan S. Chandrashekar, Sooryanarayana Varambally, Rajeev S. Samant & Lalita A. Shevde
Article: 1548241
Published online: 12 Dec 2018
AbstractforInhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer | Full Text | References | PDF (2.6 MB) | EPUB | Supplemental
  • 4125 Views
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Article
CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches
Elise Ramia, Anna Maria Chiaravalli, Farah Bou Nasser Eddine, Alessandra Tedeschi, Fausto Sessa, Roberto S. Accolla & Greta Forlani
Article: 1548243
Published online: 26 Nov 2018
AbstractforCIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches | Full Text | References | PDF (3.1 MB) | EPUB | Supplemental
  • 1577 Views
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Article
PD-1 signaling modulates interferon-γ production by Gamma Delta (γδ) T-Cells in response to leukemia
Timm Hoeres, Elisabeth Holzmann, Manfred Smetak, Josef Birkmann & Martin Wilhelm
Article: 1550618
Published online: 14 Dec 2018
AbstractforPD-1 signaling modulates interferon-γ production by Gamma Delta (γδ) T-Cells in response to leukemia | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 3349 Views
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Article
Anticancer effects of anti-CD47 immunotherapy in vivo
Kristina Iribarren, Aitziber Buque, Laura Mondragon, Wei Xie, Sarah Lévesque, Jonathan Pol, Laurence Zitvogel, Oliver Kepp & Guido Kroemer
Article: 1550619
Published online: 11 Dec 2018
AbstractforAnticancer effects of anti-CD47 immunotherapy in vivo | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 2810 Views
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Article
Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model
Jose M. Ayuso, Regan Truttschel, Max M. Gong, Mouhita Humayun, Maria Virumbrales-Munoz, Ross Vitek, Mildred Felder, Stephen D. Gillies, Paul Sondel, Kari B. Wisinski, Manish Patankar, David J. Beebe & Melissa C. Skala
Article: 1553477
Published online: 12 Dec 2018
AbstractforEvaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 6179 Views
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Article
A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo
Mathias Vormehr, Katharina Reinhard, Renata Blatnik, Kathrin Josef, Jan David Beck, Nadja Salomon, Martin Suchan, Abderraouf Selmi, Fulvia Vascotto, Johannes Zerweck, Holger Wenschuh, Mustafa Diken, Sebastian Kreiter, Özlem Türeci, Angelika B. Riemer & Ugur Sahin
Article: 1553478
Published online: 24 Dec 2018
AbstractforA non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo | Full Text | References | PDF (3.9 MB) | EPUB | Supplemental
  • 2772 Views
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Article
Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma
Cédric Rossi, Pauline Gravelle, Emilie Decaup, Julie Bordenave, Mary Poupot, Marie Tosolini, Don-Marc Franchini, Camille Laurent, Renaud Morin, Jean-Michel Lagarde, Loïc Ysebaert, Laetitia Ligat, Christine Jean, Ariel Savina, Christian Klein, Alba Matas Céspedes, Patricia Perez-Galan, Jean-Jacques Fournié & Christine Bezombes
Article: 1554175
Published online: 17 Dec 2018
AbstractforBoosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma | Full Text | References | PDF (3 MB) | EPUB | Supplemental
  • 2009 Views
  • 45 CrossRef citations
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Article
Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors
Raffaella Fontana, Laura Raccosta, Lucrezia Rovati, Knut R. Steffensen, Aida Paniccia, Tomas Jakobsson, Giulio Melloni, Alessandro Bandiera, Giorgia Mangili, Alice Bergamini, Daniela Maggioni, Claudio Doglioni, Roberto Crocchiolo, Marina Cella, Michela Mattioli, Cristina Battaglia, Marco Colonna & Vincenzo Russo
Article: 1554967
Published online: 13 Dec 2018
AbstractforNuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors | Full Text | References | PDF (3.2 MB) | EPUB | Supplemental
  • 1871 Views
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Article
The regulatory capacity of B cells directs the aggressiveness of CLL
Audrey Mohr, Marie Cumin, Cristina Bagacean, Pierre Pochard, Christelle Le Dantec, Sophie Hillion, Yves Renaudineau, Christian Berthou, Adrian Tempescul, Hussam Saad, Jacques-Olivier Pers, Anne Bordron & Christophe Jamin
Article: 1554968
Published online: 12 Dec 2018
AbstractforThe regulatory capacity of B cells directs the aggressiveness of CLL | Full Text | References | PDF (2 MB) | EPUB
  • 1076 Views
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Article
Neoantigen characteristics in the context of the complete predicted MHC class I self-immunopeptidome
Scott D. Brown & Robert A. Holt
Article: 1556080
Published online: 22 Dec 2018
AbstractforNeoantigen characteristics in the context of the complete predicted MHC class I self-immunopeptidome | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 3364 Views
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Open Access
Article
A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma
Thijs T. Wind, Mathilde Jalving, Jacco J. de Haan, Elisabeth G. E. de Vries, Marcel A. T. M. van Vugt, Dirk-Jan Reijngoud, Rozemarijn S. van Rijn, John B. A. G. Haanen, Christian U. Blank, Geke A. P. Hospers & Rudolf S. N. Fehrmann
Article: 1558664
Published online: 03 Jan 2019
AbstractforA large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 1752 Views
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Article
Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma
Axel Lechner, Hans A. Schlößer, Martin Thelen, Kerstin Wennhold, Sacha I. Rothschild, Ramona Gilles, Alexander Quaas, Oliver G. Siefer, Christian U. Huebbers, Engin Cukuroglu, Jonathan Göke, Axel Hillmer, Birgit Gathof, Moritz F. Meyer, Jens P. Klussmann, Alexander Shimabukuro-Vornhagen, Sebastian Theurich, Dirk Beutner & Michael von Bergwelt-Baildon
Article: 1535293
Published online: 10 Jan 2019
AbstractforTumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 4390 Views
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Article
Local immunomodulation combined to radiofrequency ablation results in a complete cure of local and distant colorectal carcinoma
Katia Lemdani, Nathalie Mignet, Vincent Boudy, Johanne Seguin, Edward Oujagir, Olivia Bawa, Frédérique Peschaud, Jean-François Emile, Claude Capron & Robert Malafosse
Article: 1550342
Published online: 10 Jan 2019
AbstractforLocal immunomodulation combined to radiofrequency ablation results in a complete cure of local and distant colorectal carcinoma | Full Text | References | PDF (2.7 MB) | EPUB | Supplemental
  • 3567 Views
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Article
Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1α antibody, in a phase III randomized study of advanced colorectal cancer
Razelle Kurzrock, Tamas Hickish, Lucjan Wyrwicz, Mark Saunders, Qian Wu, Michael Stecher, Prasant Mohanty, Charles A. Dinarello & John Simard
Article: 1551651
Published online: 12 Dec 2018
AbstractforInterleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1α antibody, in a phase III randomized study of advanced colorectal cancer | Full Text | References | PDF (775 KB) | EPUB
  • 2322 Views
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Article
Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
Nadia Mensali, Amalie Grenov, Niladri Bhusan Pati, Pierre Dillard, Marit Renée Myhre, Gustav Gaudernack, Gunnar Kvalheim, Else Marit Inderberg, Oddmund Bakke & Sébastien Wälchli
Article: 1558663
Published online: 11 Jan 2019
AbstractforAntigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity | Full Text | References | PDF (3.3 MB) | EPUB | Supplemental
  • 3248 Views
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Article
Exosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention
Kavitha Yaddanapudi, Shuhan Meng, Aaron G. Whitt, Numan Al Rayyan, Jamaal Richie, Allison Tu, John W. Eaton & Chi Li
Article: 1561119
Published online: 09 Jan 2019
AbstractforExosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 2113 Views
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