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OncoImmunology Volume 9, 2020 - Issue 1
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Review

Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis

Boris Shulgina M&S Decisions LLC, Moscow, RussiaView further author information
,
Yuri Kosinskya M&S Decisions LLC, Moscow, RussiaView further author information
,
Andrey Omelchenkoa M&S Decisions LLC, Moscow, RussiaView further author information
,
Lulu Chub PK Sciences Modeling & Simulation, Novartis Institutes of BioMedical Research, Cambridge, MA, USAView further author information
,
Ganesh Mugunduc Clinical Pharmacology & Quantitative Pharmacology, R&D BioPharmaceuticals, AstraZeneca, Waltham, MA, USAView further author information
,
Sergey Aksenovc Clinical Pharmacology & Quantitative Pharmacology, R&D BioPharmaceuticals, AstraZeneca, Waltham, MA, USAView further author information
,
Rodrigo Pimenteld Medical Affairs, AstraZeneca, Gaithersburg, MD, USAView further author information
,
Garrett DeYuliad Medical Affairs, AstraZeneca, Gaithersburg, MD, USAView further author information
,
Geoffrey Kime Applied Innovation, BeiGene, Cambridge, MA, USAView further author information
,
Kirill Peskova M&S Decisions LLC, Moscow, Russia;f I.M.Sechenov first Moscow State Medical University of the Russian Ministry of Health, Moscow, RussiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0678-5729View further author information
ORCID Icon &
Gabriel Helmlingerg Clinical Pharmacology & Toxicology, Obsidian Therapeutics, Cambridge, MA, USAORCID Iconhttps://orcid.org/0000-0003-4925-2463View further author information
ORCID Icon show all
Article: 1748982 | Received 29 Aug 2019, Accepted 21 Jan 2020, Published online: 21 May 2020

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Raquel S Laureano, Jenny Sprooten, Isaure Vanmeerbeerk, Daniel M Borras, Jannes Govaerts, Stefan Naulaerts, Zwi N Berneman, Benoit Beuselinck, Kalijn F Bol, Jannie Borst, an Coosemans, Angeliki Datsi, Jitka Fučíková, Lisa Kinget, Bart Neyns, Gerty Schreibelt, Evelien Smits, Rüdiger V Sorg, Radek Spisek, Kris Thielemans, Sandra Tuyaerts, Steven De Vleeschouwer, I Jolanda M de Vries, Yanling Xiao & Abhishek D Garg. (2022) Trial watch: Dendritic cell (DC)-based immunotherapy for cancer. OncoImmunology 11:1.
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Aditya Arra, Maximilian Pech, Hang Fu, Holger Lingel, Franziska Braun, Christian Beyer, Myra Spiliopoulou, Barbara M. Bröker, Karen Lampe, Christoph Arens, Katrin Vogel, Mandy Pierau & Monika C. Brunner-Weinzierl. (2021) Immune-checkpoint blockade of CTLA-4 (CD152) in antigen-specific human T-cell responses differs profoundly between neonates, children, and adults. OncoImmunology 10:1.
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Irina Kareva & Jana L. Gevertz. (2024) Mitigating non-genetic resistance to checkpoint inhibition based on multiple states of immune exhaustion. npj Systems Biology and Applications 10:1.
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Bao-Toan Nguyen Dang, Taeg Kyu Kwon, Sooyeun Lee, Jee-Heon Jeong & Simmyung Yook. (2024) Nanoparticle-based immunoengineering strategies for enhancing cancer immunotherapy. Journal of Controlled Release 365, pages 773-800.
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Chien-Hsiang Kao, Hao Lin, Chien-Ting Liu, Yu-Che Ou, Hung-Chun Fu, Chia-Che Wu & Chen-Hsuan Wu. (2023) Real-world efficacy and safety of low-dose pembrolizumab in patients with advanced and refractory gynecologic cancers. Journal of the Formosan Medical Association.
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Yumin Zheng, Huijing Dong, Yixuan Yu, Zixin Hu, Chongxiang Xue, Xu Zhang & Huijuan Cui. (2023) Treatment-related adverse events of immune checkpoint inhibitors combined with angiogenesis inhibitors in advanced lung cancer: A systematic review and meta-analysis. International Immunopharmacology 123, pages 110785.
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Ryosuke Matsukane, Kimitaka Suetsugu, Kojiro Hata, Keisuke Matsuda, Satoshi Nakao, Haruna Minami, Hiroyuki Watanabe, Takeshi Hirota, Nobuaki Egashira & Ichiro Ieiri. (2023) Systematic surveillance of immune-related adverse events in clinical practice and impact of subsequent steroid medication on survival outcomes. International Journal of Clinical Oncology 28:7, pages 860-871.
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Kimberly M. Winges & Lynn K. Gordon. (2022) Neuro-ophthalmic complications of immune checkpoint inhibitor therapy: Current status and future directions. Frontiers in Ophthalmology 2.
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Anna M. Czarnecka, Marcin Kleibert, Iga Płachta, Paweł Rogala, Michał Wągrodzki, Przemysław Leszek & Piotr Rutkowski. (2022) Myocarditis Induced by Immunotherapy in Metastatic Melanoma—Review of Literature and Current Guidelines. Journal of Clinical Medicine 11:17, pages 5182.
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Phyllis Chan, Kirill Peskov & Xuyang Song. (2022) Applications of Model-Based Meta-Analysis in Drug Development. Pharmaceutical Research 39:8, pages 1761-1777.
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Tadashi Mizukoshi, Hidenori Fukuoka & Yutaka Takahashi. (2022) Immune checkpoint inhibitor-related hypophysitis. Best Practice & Research Clinical Endocrinology & Metabolism 36:3, pages 101668.
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Kazumasa Soma, Tsutomu Nishida, Naoto Osugi, Osamu Morimura, Shiro Adachi, Yoshifumi Fujii, Aya Sugimoto, Kaori Mukai, Dai Nakamatsu, Kengo Matsumoto & Masashi Yamamoto. (2021) Nivolumab dose escalation triggered immune checkpoint inhibitor-induced colitis after 147 weeks of prolonged stable use in a patient with lung cancer: a case report. Clinical Journal of Gastroenterology 15:1, pages 128-133.
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Niccolò Bartalucci & Lorenzo Galluzzi. 2022. Cellular and Molecular Aspects of Myeloproliferative Neoplasms – Part B. Cellular and Molecular Aspects of Myeloproliferative Neoplasms – Part B ix xx .
Carolina Czichos, Bartlomiej Wawrzynów, Christos Chamalis & Burkhard von Jagow. (2021) Beidseitige Nivolumab-assoziierte Vogt-Koyanagi-Harada-artige Uveitis bei einem Patienten mit metastasiertem Nierenzellkarzinom. Klinische Monatsblätter für Augenheilkunde 238:06, pages 711-714.
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R. Kleef, R. Nagy, A. Baierl, V. Bacher, H. Bojar, D. L. McKee, R. Moss, N. H. Thoennissen, M. Szász & T. Bakacs. (2020) Low-dose ipilimumab plus nivolumab combined with IL-2 and hyperthermia in cancer patients with advanced disease: exploratory findings of a case series of 131 stage IV cancers – a retrospective study of a single institution. Cancer Immunology, Immunotherapy 70:5, pages 1393-1403.
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Chiara Cremolini, Emanuela Vitale, Raffaella Rastaldo & Claudia Giachino. (2021) Advanced Nanotechnology for Enhancing Immune Checkpoint Blockade Therapy. Nanomaterials 11:3, pages 661.
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Niccolò Bartalucci & Lorenzo Galluzzi. 2021. Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A. Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A ix xx .
Francesco Del Galdo. (2020) New lessons for an old problem: ASSET open-label extension. The Lancet Rheumatology 2:12, pages e726-e727.
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Layal Antoury, Nolan J. Maloney, Daniel Q. Bach, Carolyn Goh & Kyle Cheng. (2020) Alopecia areata as an immune‐related adverse event of immune checkpoint inhibitors: A review. Dermatologic Therapy 33:6.
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