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Human Vaccines & Immunotherapeutics Volume 13, 2017 - Issue 3
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Research Papers

Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

Christopher A. SeidSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Kathryn M. JonesSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA
,
Jeroen PolletSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA
,
Brian KeeganSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Elissa HudspethSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Molly HammondSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Junfei WeiSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
C. Patrick McAteeSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Leroy VersteegSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Amanda GutierrezSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Zhuyun LiuSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA
,
Bin ZhanSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA
,
Jonathan L. RespressSouthwest Electronic Energy Medical Research Institute (SWEMRI), Missouri City, TX, USA
,
Ulrich StrychSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA
,
Maria Elena BottazziSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USACorrespondence[email protected]
&
Peter J. HotezSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA;James A. Baker III Institute for Public Policy, Rice University, Houston, TX, USA
 show all
Pages 621-633 | Received 23 Jun 2016, Accepted 26 Sep 2016, Published online: 18 Dec 2016

Citations (33)

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Wen-Hsiang Chen, Ulrich Strych, Maria Elena Bottazzi & Yi-Pin Lin. (2022) Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights. Expert Review of Vaccines 21:10, pages 1405-1417.
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Kathryn M. Jones, Cristina Poveda, Leroy Versteeg, Maria Elena Bottazzi & Peter J. Hotez. (2022) Preclinical advances and the immunophysiology of a new therapeutic Chagas disease vaccine. Expert Review of Vaccines 21:9, pages 1185-1203.
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Abel Ramos-Vega, Elizabeth Monreal-Escalante, Eric Dumonteil, Bernardo Bañuelos-Hernández & Carlos Angulo. (2021) Plant-made vaccines against parasites: bioinspired perspectives to fight against Chagas disease. Expert Review of Vaccines 20:11, pages 1373-1388.
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