Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

Christopher A. SeidSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Kathryn M. JonesSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA

Jeroen PolletSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA

Brian KeeganSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Elissa HudspethSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Molly HammondSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Junfei WeiSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

C. Patrick McAteeSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Leroy VersteegSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Amanda GutierrezSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Zhuyun LiuSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA

Bin ZhanSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA

Jonathan L. RespressSouthwest Electronic Energy Medical Research Institute (SWEMRI), Missouri City, TX, USA

Ulrich StrychSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA

Maria Elena BottazziSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USACorrespondence[email protected]

Peter J. HotezSabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, Houston, TX, USA;Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA;James A. Baker III Institute for Public Policy, Rice University, Houston, TX, USA

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Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

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Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

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