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Human Vaccines & Immunotherapeutics Volume 13, 2017 - Issue 12: The International Society for Vaccines 2016 Annual Congress, Boston, Oct. 2-4, 2016
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Research Papers

HIV Env conserved element DNA vaccine alters immunodominance in macaques

Xintao HuHuman Retrovirus Pathogenesis Section, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
,
Antonio ValentinHuman Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
,
Margherita RosatiHuman Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
,
Siriphan ManocheewaDepartments of Microbiology, University of Washington, Seattle, WA, USA
,
Candido AliceaHuman Retrovirus Pathogenesis Section, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
,
Bhabadeb ChowdhuryHuman Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
,
Jenifer BearHuman Retrovirus Pathogenesis Section, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
,
Kate E. BroderickInovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USA
,
Niranjan Y. SardesaiInovio Pharmaceuticals, Inc., Plymouth Meeting, PA, USAORCID Iconhttp://orcid.org/0000-0001-6920-1167
ORCID Icon,
Sylvie Le GallRagon Institute of MGH, MIT and Harvard, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA
,
James I. MullinsDepartments of Microbiology, University of Washington, Seattle, WA, USA;Departments of Medicine, University of Washington, Seattle, WA, USA;Departments of Global Health, University of Washington, Seattle, WA, USA;Departments of Laboratory Medicine, University of Washington, Seattle, WA, USA
,
George N. PavlakisHuman Retrovirus Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA
&
Barbara K. FelberHuman Retrovirus Pathogenesis Section, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USACorrespondence[email protected]
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Pages 2859-2871 | Received 09 Apr 2017, Accepted 04 Jun 2017, Published online: 07 Nov 2017

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Read on this site (3)

Paul Munson. (2022) Progress Towards a Therapeutic HIV DNA Vaccine. Expert Review of Vaccines 21:6, pages 783-798.
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Mohammad Arif Rahman & Marjorie Robert-Guroff. (2019) Accelerating HIV vaccine development using non-human primate models. Expert Review of Vaccines 18:1, pages 61-73.
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Xintao Hu, Zhongyan Lu, Antonio Valentin, Margherita Rosati, Kate E. Broderick, Niranjan Y. Sardesai, Preston A. Marx, James I. Mullins, George N. Pavlakis & Barbara K. Felber. (2018) Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques. Human Vaccines & Immunotherapeutics 14:9, pages 2163-2177.
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Zhujun Ao, Lijun Wang, Hiva Azizi, Titus Abiola Olukitibi, Gary Kobinger & Xiaojian Yao. (2021) Development and Evaluation of an Ebola Virus Glycoprotein Mucin-Like Domain Replacement System as a New Dendritic Cell-Targeting Vaccine Approach against HIV-1. Journal of Virology 95:15.
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Lianxiao Liu, Haixia Gao, Chuanxin Guo, Tao Liu, Ning Li & Qijun Qian. (2021) Therapeutic Mechanism of Nucleic Acid Drugs. ChemistrySelect 6:5, pages 903-916.
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Tatiana M. Garcia-Bates, Mariana L. Palma, Renee R. Anderko, Denise C. Hsu, Jintanat Ananworanich, Bette T. Korber, Gaurav D. Gaiha, Nittaya Phanuphak, Rasmi Thomas, Sodsai Tovanabutra, Bruce D. Walker, John W. Mellors, Paolo A. Piazza, Eugene Kroon, Sharon A. Riddler, Nelson L. Michael, Charles R. Rinaldo & Robbie B. Mailliard. (2021) Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes. EBioMedicine 63, pages 103175.
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Xintao Hu, Barbara K. Felber & Antonio Valentin. 2021. DNA Vaccines. DNA Vaccines 113 131 .
Santhi Devasundaram, Margherita Rosati, Antonio Valentin, Svenja Weiss, Vincenza Itri, Hung V. Trinh, Jenifer Bear, Bhabadeb Chowdhury, Celia C. LaBranche, David Montefiori, Guido Ferrari, Mangala Rao, Xiang-Peng Kong, Susan Zolla-Pazner, George N. Pavlakis & Barbara K. Felber. (2020) Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques. Journal of Virology 95:2.
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Anil Verma, Brian A. Schmidt, Sonny R. Elizaldi, Nancy K. Nguyen, Korey A. Walter, Zoltan Beck, Hung V. Trinh, Ashok R. Dinasarapu, Yashavanth Shaan Lakshmanappa, Niharika N. Rane, Gary R. Matyas, Mangala Rao, Xiaoying Shen, Georgia D. Tomaras, Celia C. LaBranche, Keith A. Reimann, David H. Foehl, Johannes S. Gach, Donald N. Forthal, Pamela A. Kozlowski, Rama R. Amara & Smita S. Iyer. (2020) Impact of T h 1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques . Journal of Virology 94:6.
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Tayebeh Rezaei, Saeed Khalili, Behzad Baradaran, Jafar Mosafer, Sarah Rezaei, Ahad Mokhtarzadeh & Miguel de la Guardia. (2019) Recent advances on HIV DNA vaccines development: Stepwise improvements to clinical trials. Journal of Controlled Release 316, pages 116-137.
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Julie Boucau & Sylvie Le Gall. (2019) Antigen processing and presentation in HIV infection. Molecular Immunology 113, pages 67-74.
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Kunihiko Yamashita. 2019. Therapeutic Vaccines as Novel Immunotherapy. Therapeutic Vaccines as Novel Immunotherapy 57 65 .
Matthew S. Sutton, Amy Ellis-Connell, Ryan V. Moriarty, Alexis J. Balgeman, Dane Gellerup, Gabrielle Barry, Andrea M. Weiler, Thomas C. Friedrich & Shelby L. O'Connor. (2018) Acute-Phase CD4 + T Cell Responses Targeting Invariant Viral Regions Are Associated with Control of Live Attenuated Simian Immunodeficiency Virus . Journal of Virology 92:21.
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Xintao HuAntonio ValentinYanhui CaiFrances DaytonMargherita RosatiEric G. Ramírez-SalazarViraj KulkarniKate E. BroderickNiranjan Y. SardesaiLinda S. WyattPatricia L. EarlBernard MossJames I. MullinsGeorge N. PavlakisBarbara K. Felber. (2018) DNA Vaccine–Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination. Human Gene Therapy 29:9, pages 1029-1043.
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Benedikt Asbach, Johannes P. Meier, Matthias Pfeifer, Josef Köstler & Ralf Wagner. (2018) Computational Design of Epitope-Enriched HIV-1 Gag Antigens with Preserved Structure and Function for Induction of Broad CD8+ T Cell Responses. Scientific Reports 8:1.
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