4,725
Views
49
CrossRef citations to date
0
Altmetric
Addendum

The immune system in Duchenne muscular dystrophy: Friend or foe

, &
Article: e1010966 | Received 21 Nov 2014, Accepted 19 Jan 2015, Published online: 17 Mar 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Shouta Miyatake, Yuko Shimizu-Motohashi, Shin’ichi Takeda & Yoshitsugu Aoki. (2016) Anti-inflammatory drugs for Duchenne muscular dystrophy: focus on skeletal muscle-releasing factors. Drug Design, Development and Therapy 10, pages 2745-2758.
Read now
Heidi R. Fuller, Laura C. Graham, Maica Llavero Hurtado & Thomas M. Wishart. (2016) Understanding the molecular consequences of inherited muscular dystrophies: advancements through proteomic experimentation. Expert Review of Proteomics 13:7, pages 659-671.
Read now
Dariusz C. Górecki. (2016) Dystrophin: The dead calm of a dogma. Rare Diseases 4:1.
Read now

Articles from other publishers (46)

Zhi Jiang, Hongmei Liao, Liwen Wu, Wenjing Hu, Liming Yang, Bo Chen, Zeshu Ning, Jingwen Tang, Rong Xu, Mei Chen, Feng Guo & Shulei Liu. (2023) Association between blood eosinophil count and Duchenne muscular dystrophy severity and prognosis: a retrospective cohort study. Italian Journal of Pediatrics 49:1.
Crossref
Addeli Bez Batti Angulski, Nora Hosny, Houda Cohen, Ashley A. Martin, Dongwoo Hahn, Jack Bauer & Joseph M. Metzger. (2023) Duchenne muscular dystrophy: disease mechanism and therapeutic strategies. Frontiers in Physiology 14.
Crossref
Ziyu Chen, HaiQiang Lan, ZhaoHong Liao, JingWen Huang, XiaoTing Jian, Jijie Hu & Hua Liao. (2022) Regulatory T cells-centered regulatory networks of skeletal muscle inflammation and regeneration. Cell & Bioscience 12:1.
Crossref
Luana Tripodi, Davide Molinaro, Francesco Fortunato, Carolina Mella, Barbara Cassani, Yvan Torrente & Andrea Farini. (2022) Immunoproteasome Inhibition Ameliorates Aged Dystrophic Mouse Muscle Environment. International Journal of Molecular Sciences 23:23, pages 14657.
Crossref
Katherine G. English, Andrea L. Reid, Adrienne Samani, Gerald J. F. Coulis, S. Armando Villalta, Christopher J. Walker, Sharon Tamir & Matthew S. Alexander. (2022) Next-Generation SINE Compound KPT−8602 Ameliorates Dystrophic Pathology in Zebrafish and Mouse Models of DMD. Biomedicines 10:10, pages 2400.
Crossref
Marielle Saclier, Giuseppe Angelini, Chiara Bonfanti, Giada Mura, Giulia Temponi & Graziella Messina. (2022) Selective ablation of Nfix in macrophages attenuates muscular dystrophy by inhibiting fibro‐adipogenic progenitor‐dependent fibrosis . The Journal of Pathology 257:3, pages 352-366.
Crossref
Carlos D. Vera, Angela Zhang, Paul D. Pang & Joseph C. Wu. (2022) Treating Duchenne Muscular Dystrophy: The Promise of Stem Cells, Artificial Intelligence, and Multi-Omics. Frontiers in Cardiovascular Medicine 9.
Crossref
Jacopo Morroni, Leonardo Schirone, Valentina Valenti, Clemens Zwergel, Carles Sánchez Riera, Sergio Valente, Daniele Vecchio, Sonia Schiavon, Rino Ragno, Antonello Mai, Sebastiano Sciarretta, Biliana Lozanoska-Ochser & Marina Bouchè. (2022) Inhibition of PKCθ Improves Dystrophic Heart Phenotype and Function in a Novel Model of DMD Cardiomyopathy. International Journal of Molecular Sciences 23:4, pages 2256.
Crossref
Lizzia Raffaghello, Elisa Principi, Serena Baratto, Chiara Panicucci, Sara Pintus, Francesca Antonini, Genny Del Zotto, Andrea Benzi, Santina Bruzzone, Paolo Scudieri, Carlo Minetti, Elisabetta Gazzerro & Claudio Bruno. (2022) P2X7 Receptor Antagonist Reduces Fibrosis and Inflammation in a Mouse Model of Alpha-Sarcoglycan Muscular Dystrophy. Pharmaceuticals 15:1, pages 89.
Crossref
Luana Tripodi, Chiara Villa, Davide Molinaro, Yvan Torrente & Andrea Farini. (2021) The Immune System in Duchenne Muscular Dystrophy Pathogenesis. Biomedicines 9:10, pages 1447.
Crossref
Heike Kölbel, Corinna Preuße, Lukas Brand, Arpad Moers, Adela Della Marina, Markus Schuelke, Andreas Roos, Hans‐Hilmar Goebel, Ulrike Schara‐Schmidt & Werner Stenzel. (2021) Inflammation, fibrosis and skeletal muscle regeneration in LGMDR9 are orchestrated by macrophages. Neuropathology and Applied Neurobiology 47:6, pages 856-866.
Crossref
Xiangsheng Liu, Xiaodong Xie, Jinhong Jiang, Matthew Lin, Emily Zheng, Waveley Qiu, Iwin Yeung, Motao Zhu, Qinglin Li, Tian Xia & Huan Meng. (2021) Use of Nanoformulation to Target Macrophages for Disease Treatment. Advanced Functional Materials 31:38, pages 2104487.
Crossref
Andrea Farini, Chiara Villa, Luana Tripodi, Mariella Legato & Yvan Torrente. (2021) Role of Immunoglobulins in Muscular Dystrophies and Inflammatory Myopathies. Frontiers in Immunology 12.
Crossref
Andrea L. Reid & Matthew S. Alexander. (2021) The Interplay of Mitophagy and Inflammation in Duchenne Muscular Dystrophy. Life 11:7, pages 648.
Crossref
Andrea Farini, Clementina Sitzia, Chiara Villa, Barbara Cassani, Luana Tripodi, Mariella Legato, Marzia Belicchi, Pamela Bella, Caterina Lonati, Stefano Gatti, Massimiliano Cerletti & Yvan Torrente. (2021) Defective dystrophic thymus determines degenerative changes in skeletal muscle. Nature Communications 12:1.
Crossref
Jenna M. Kastenschmidt, Gerald Coulis, Philip K. Farahat, Phillip Pham, Rodolfo Rios, Therese T. Cristal, Ali H. Mannaa, Rachel E. Ayer, Rayan Yahia, Archis A. Deshpande, Brandon S. Hughes, Adam K. Savage, Carlee R. Giesige, Scott Q. Harper, Richard M. Locksley, Tahseen Mozaffar & S. Armando Villalta. (2021) A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Reports 35:2, pages 108997.
Crossref
Madalina-Gabriela Barbu, Andreea-Elena Boboc, Lidia Filip, Oana-Larisa Bugnar, Dragos Cretoiu, Nicolae Suciu, Oana Daniela Toader, Sanda Maria Cretoiu & Silviu-Cristian Voinea. 2021. Background and Management of Muscular Atrophy. Background and Management of Muscular Atrophy.
Niraj Kumar Srivastava, Ramakant Yadav & Somnath Mukherjee. 2021. The Molecular Immunology of Neurological Diseases. The Molecular Immunology of Neurological Diseases 51 74 .
Paul Dowling, Stephen Gargan, Margit Zweyer, Michael Henry, Paula Meleady, Dieter Swandulla & Kay Ohlendieck. (2020) Proteome-wide Changes in the mdx-4cv Spleen due to Pathophysiological Cross Talk with Dystrophin-Deficient Skeletal Muscle. iScience 23:9, pages 101500.
Crossref
Brandon N. VanderVeen, E. Angela Murphy & James A. Carson. (2020) The Impact of Immune Cells on the Skeletal Muscle Microenvironment During Cancer Cachexia. Frontiers in Physiology 11.
Crossref
Jana Zschüntzsch, Pia Vanessa Jouvenal, Yaxin Zhang, Florian Klinker, Malte Tiburcy, David Liebetanz, Dörthe Malzahn, Heinrich Brinkmeier & Jens Schmidt. (2020) Long‐term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy. Journal of Cachexia, Sarcopenia and Muscle 11:4, pages 1018-1031.
Crossref
PadmaKumar NarayananBrian R. CurtisLijiang ShenEugene SchneiderJoseph A. TamiSuzanne PazSebastien A. BurelLi-Jung TaiTodd MachemerT. Jesse KwohShuting XiaSanford J. ShattilJoseph L. WitztumJeffery A. EngelhardtScott P. HenryBrett P. MoniaSteven G. Hughes. (2020) Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia. Nucleic Acid Therapeutics 30:2, pages 94-103.
Crossref
Melina Messing, Sia Cecilia Jan-Abu & Kelly McNagny. (2020) Group 2 Innate Lymphoid Cells: Central Players in a Recurring Theme of Repair and Regeneration. International Journal of Molecular Sciences 21:4, pages 1350.
Crossref
Yvan Torrente, Pamela Bella, Luana Tripodi, Chiara Villa & Andrea Farini. (2020) Role of Insulin-Like Growth Factor Receptor 2 across Muscle Homeostasis: Implications for Treating Muscular Dystrophy. Cells 9:2, pages 441.
Crossref
Giuseppe Rizzo, Rosanna Di Maggio, Anna Benedetti, Jacopo Morroni, Marina Bouche & Biliana Lozanoska-Ochser. (2020) Splenic Ly6Chi monocytes are critical players in dystrophic muscle injury and repair. JCI Insight 5:2.
Crossref
Rylie M. Hightower, Andrea L. Reid, Devin E. Gibbs, Yimin Wang, Jeffrey J. Widrick, Louis M. Kunkel, Jenna M. Kastenschmidt, S. Armando Villalta, Thomas van Groen, Hua Chang, Savanna Gornisiewicz, Yosef Landesman, Sharon Tamir & Matthew S. Alexander. (2020) The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice. Molecular Therapy 28:1, pages 189-201.
Crossref
Christopher N.J. Young, Maxime R.F. Gosselin, Robin Rumney, Aleksandra Oksiejuk, Natalia Chira, Lukasz Bozycki, Paweł Matryba, Kacper Łukasiewicz, Alex P. Kao, Joseph Dunlop, Samuel C. Robson, Krzysztof Zabłocki & Dariusz C. Górecki. (2020) Total Absence of Dystrophin Expression Exacerbates Ectopic Myofiber Calcification and Fibrosis and Alters Macrophage Infiltration Patterns. The American Journal of Pathology 190:1, pages 190-205.
Crossref
Simon Alexander Kranig, Raphaela Tschada, Maylis Braun, Christian Patry, Johannes Pöschl, David Frommhold & Hannes Hudalla. (2019) Dystrophin deficiency promotes leukocyte recruitment in mdx mice. Pediatric Research 86:2, pages 188-194.
Crossref
Douglas Florindo Pinheiro, Rafael F. da Silva, Thiago Morais Barbosa, Jaciara F. G. Gama, Aline C. Gomes, Thereza Quirico-Santos & Jussara Lagrota-Candido. (2019) Omentum acts as a regulatory organ controlling skeletal muscle repair of mdx mice diaphragm. Cell and Tissue Research 377:2, pages 269-279.
Crossref
Clementina Sitzia, Mirella Meregalli, Marzia Belicchi, Andrea Farini, Maddalena Arosio, Denise Bestetti, Chiara Villa, Luca Valenti, Paolo Brambilla & Yvan Torrente. (2019) Preliminary Evidences of Safety and Efficacy of Flavonoids- and Omega 3-Based Compound for Muscular Dystrophies Treatment: A Randomized Double-Blind Placebo Controlled Pilot Clinical Trial. Frontiers in Neurology 10.
Crossref
Albert C. Sek, Ian N. Moore, Margery G. Smelkinson, Katherine Pak, Mahnaz Minai, Roberta Smith, Michelle Ma, Caroline M. Percopo & Helene F. Rosenberg. (2019) Eosinophils Do Not Drive Acute Muscle Pathology in the mdx Mouse Model of Duchenne Muscular Dystrophy. The Journal of Immunology 203:2, pages 476-484.
Crossref
Harmen Reyngoudt, Alfredo L. Lopez Kolkovsky & Pierre G. Carlier. (2019) Free intramuscular Mg 2+ concentration calculated using both 31 P and 1 H NMRS‐based pH in the skeletal muscle of Duchenne muscular dystrophy patients . NMR in Biomedicine, pages e4115.
Crossref
Francesca De SantaLaura VitielloAlessio TorcinaroElisabetta Ferraro. (2019) The Role of Metabolic Remodeling in Macrophage Polarization and Its Effect on Skeletal Muscle Regeneration. Antioxidants & Redox Signaling 30:12, pages 1553-1598.
Crossref
Jenna M. Kastenschmidt, Ali H. Mannaa, Karissa J. Muñoz & S. Armando Villalta. 2019. Muscle Gene Therapy. Muscle Gene Therapy 121 139 .
Nicole Green, Justin Walker, Alexandria Bontrager, Molly Zych & Erika R. Geisbrecht. (2018) A tissue communication network coordinating innate immune response during muscle stress. Journal of Cell Science 131:24.
Crossref
Kelley M. Virgilio, Kyle S. Martin, Shayn M. Peirce & Silvia S. Blemker. (2018) Agent-based model illustrates the role of the microenvironment in regeneration in healthy and mdx skeletal muscle . Journal of Applied Physiology 125:5, pages 1424-1439.
Crossref
Kenneth M. Estrellas, Liam Chung, Lindsay A. Cheu, Kaitlyn Sadtler, Shoumyo Majumdar, Jyothi Mula, Matthew T. Wolf, Jennifer H. Elisseeff & Kathryn R. Wagner. (2018) Biological scaffold–mediated delivery of myostatin inhibitor promotes a regenerative immune response in an animal model of Duchenne muscular dystrophy. Journal of Biological Chemistry 293:40, pages 15594-15605.
Crossref
Silvia Parolo, Luca Marchetti, Mario Lauria, Karla Misselbeck, Marie-Pier Scott-Boyer, Laura Caberlotto & Corrado Priami. (2018) Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy. PLOS ONE 13:3, pages e0194225.
Crossref
Omid Mashinchian, Addolorata Pisconti, Emmeran Le Moal & C. Florian Bentzinger. 2018. Myogenesis in Development and Disease. Myogenesis in Development and Disease 23 65 .
Harmen Reyngoudt, Suna Turk & Pierre G. Carlier. (2018) 1 H NMRS of carnosine combined with 31 P NMRS to better characterize skeletal muscle pH dysregulation in Duchenne muscular dystrophy . NMR in Biomedicine 31:1, pages e3839.
Crossref
Bruno Ghirotto Nunes, Flávio Vieira Loures, Heloisa Maria Siqueira Bueno, Erica Baroni Cangussu, Ernesto Goulart, Giuliana Castello Coatti, Elia Garcia Caldini, Antonio Condino-Neto & Mayana Zatz. (2017) Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin–utrophin double knockout mice. European Journal of Human Genetics 25:12, pages 1388-1396.
Crossref
David P. Burns, Jane Rowland, Leonie Canavan, Kevin H. Murphy, Molly Brannock, Dervla O'Malley, Ken D. O'Halloran & Deirdre Edge. (2017) Restoration of pharyngeal dilator muscle force in dystrophin-deficient ( mdx ) mice following co-treatment with neutralizing interleukin-6 receptor antibodies and urocortin 2 . Experimental Physiology 102:9, pages 1177-1193.
Crossref
Sandra Murphy, Paul Dowling, Margit Zweyer, Michael Henry, Paula Meleady, Rustam R. Mundegar, Dieter Swandulla & Kay Ohlendieck. (2017) Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy. International Journal of Molecular Medicine 39:6, pages 1357-1370.
Crossref
Sandra Murphy, Heinrich Brinkmeier, Mirjam Krautwald, Michael Henry, Paula Meleady & Kay Ohlendieck. (2017) Proteomic profiling of the dystrophin complex and membrane fraction from dystrophic mdx muscle reveals decreases in the cytolinker desmoglein and increases in the extracellular matrix stabilizers biglycan and fibronectin. Journal of Muscle Research and Cell Motility 38:2, pages 251-268.
Crossref
Boel De Paepe. 2017. Cytokine Effector Functions in Tissues. Cytokine Effector Functions in Tissues 149 162 .
Sébastien S. Dufresne, Jérôme Frenette & Nicolas A. Dumont. (2016) Inflammation et régénération musculaire. médecine/sciences 32:6-7, pages 591-597.
Crossref