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Research Article

Apathy in amyotrophic lateral sclerosis: insights from Dimensional Apathy Scale

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Pages 434-442 | Received 05 Nov 2016, Accepted 21 Mar 2017, Published online: 21 Apr 2017

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Mansur A. Kutlubaev, Jashelle Caga, Ying Xu, Daria K. Areprintseva, Ekaterina V. Pervushina & Matthew C. Kiernan. (2023) Apathy in amyotrophic lateral sclerosis: systematic review and meta-analysis of frequency, correlates, and outcomes. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24:1-2, pages 14-23.
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Tina Taule, Annbjørg Spilde Morland, Jörg Aßmus, Ole-Bjørn Tysnes & Tiina Rekand. (2022) Translation, cultural adaptation, and validation of a screening test for cognitive and behavioural changes in amyotrophic lateral sclerosis. Disability and Rehabilitation 44:23, pages 7069-7077.
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Isabel K. Gosselt, Tanja C. W. Nijboer & Michael A. Van Es. (2020) An overview of screening instruments for cognition and behavior in patients with ALS: selecting the appropriate tool for clinical practice. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21:5-6, pages 324-336.
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William Huynh, Rebekah Ahmed, Colin J. Mahoney, Chilan Nguyen, Sicong Tu, Jashelle Caga, Patricia Loh, Cindy S-Y Lin & Matthew C. Kiernan. (2020) The impact of cognitive and behavioral impairment in amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics 20:3, pages 281-293.
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Ratko Radakovic, Sarah McGrory, Siddharthan Chandran, Robert Swingler, Suvankar Pal, Laura Stephenson, Shuna Colville, Judy Newton, John M. Starr & Sharon Abrahams. (2020) The brief Dimensional Apathy Scale: A short clinical assessment of apathy. The Clinical Neuropsychologist 34:2, pages 423-435.
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Jashelle Caga, Sharpley Hsieh, Elizabeth Highton-Williamson, Margaret C. Zoing, Eleanor Ramsey, Emma Devenney, Rebekah M. Ahmed, Anne Hogden & Matthew C. Kiernan. (2018) The burden of apathy for caregivers of patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19:7-8, pages 599-605.
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Annabelle Arnould, Lucien Rochat, Philippe Azouvi & Martial van der Linden. (2018) Self-appraisals and episodic memory: Different psychological factors related to patient versus informant reports of apathy in severe traumatic brain injury. Journal of Clinical and Experimental Neuropsychology 40:7, pages 650-662.
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Francesca Trojsi, Federica Di Nardo, Giulia D'Alvano, Carla Passaniti, Minoo Sharbafshaaer, Fabrizio Canale, Antonio Russo, Marcello Silvestro, Luigi Lavorgna, Mario Cirillo, Fabrizio Esposito, Gioacchino Tedeschi & Mattia Siciliano. (2023) Cognitive, behavioral, and brain functional connectivity correlates of fatigue in amyotrophic lateral sclerosis. Brain and Behavior 13:7.
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Qian-Qian Wei, Yuan Guo, Shirong Li, Tianmi Yang, Yanbing Hou, Ruwei Ou, Junyu Lin, Qirui Jiang & Huifang Shang. (2023) Prevalence and associated factors of apathy in Chinese ALS patients. Frontiers in Psychology 14.
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Marit Sofie Oseland, Unni Sveen & Tina Taule. (2023) 'It’s become a theatre’: relational experiences of family carers and people with Amyotrophic lateral sclerosis (ALS) after cognitive impairment emerges. F1000Research 12, pages 1092.
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Barbara Poletti, Federica Solca, Sabrina Maffi, Silvia Torre, Laura Carelli, Edoardo Nicolò Aiello, Roberta Ferrucci, Alberto Priori, Alessia Monti, Federico Verde, Nicola Ticozzi, Simone Migliore, Eugenia Scaricamazza, Melissa Casella, Ferdinando Squitieri, Andrea Ciammola & Vincenzo Silani. (2022) Semiology and determinants of apathy across neurodegenerative motor disorders: A comparison between amyotrophic lateral sclerosis, Parkinson’s and Huntington’s disease. Frontiers in Aging Neuroscience 14.
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Pei He, Binjun He, Shu Li, Wen Chai, Wei Rao, Yu Zhu, Wenzhi Chen, Ping Zhang, Xiong Zhang, Haili Pan & Renshi Xu. (2022) Distribution Features and Potential Effects of Serotonin in the Cerebrum of SOD1 G93A Transgenic Mice. eneuro 9:6, pages ENEURO.0001-22.2022.
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Angela Genge, Benjamin Rix Brooks, Björn Oskarsson, Alexander Kalin, Ming Ji, Stephen Apple & Laura Bower. (2022) Analysis of the US Safety Data for Edaravone (Radicava®) From the Third Year After Launch. Drugs in R&D 22:3, pages 205-211.
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Simona Raimo, Luigi Trojano, Mariachiara Gaita, Florindo d'Onofrio, Daniele Spitaleri & Gabriella Santangelo. (2022) Relationship between apathy and cognitive dysfunctions in multiple sclerosis: A 4-year prospective longitudinal study. Multiple Sclerosis and Related Disorders 63, pages 103929.
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Giulia Lafond-Brina & Anne Bonnefond. (2022) The stability of multidimensional subclinical apathy during a pandemic and its relations to psycho-behavioral factors. Scientific Reports 12:1.
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Jashelle Caga, Sicong Tu, Thanuja Dharmadasa, Nga Y. Tse, Margaret C. Zoing, William Huynh, Colin Mahoney, Rebekah M. Ahmed & Matthew C. Kiernan. (2021) Apathy is associated with parietal cortical-subcortical dysfunction in ALS. Cortex 145, pages 341-349.
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Mindaugas Jurgelis, Wei Binh Chong, Kelly J. Atkins, Patrick S. Cooper, James P. Coxon & Trevor T.-J. Chong. (2021) Heightened effort discounting is a common feature of both apathy and fatigue. Scientific Reports 11:1.
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Ratko Radakovic, Shuna Colville, Denise Cranley, John M. Starr, Suvankar Pal & Sharon Abrahams. (2020) Multidimensional Apathy in Behavioral Variant Frontotemporal Dementia, Primary Progressive Aphasia, and Alzheimer Disease. Journal of Geriatric Psychiatry and Neurology 34:5, pages 349-356.
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Kelly J. Atkins, Sophie C. Andrews, Trevor T.‐J. Chong & Julie C. Stout. (2021) Multidimensional Apathy: The Utility of the Dimensional Apathy Scale in Huntington's Disease. Movement Disorders Clinical Practice 8:3, pages 361-370.
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Teresa Salas, Ratko Radakovic, Víctor Rodriguez-Castillo, Saúl Marín, Delia Chaverri & Francisco Rodriguez-Santos. (2020) Spanish Adaptation of the Dimensional Apathy Scale (DAS) in Amyotrophic Lateral Sclerosis. Frontiers in Neurology 11.
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Ratko Radakovic, Debbie Gray, Kaitlin Dudley, Eneida Mioshi, David Dick, Giulia Melchiorre, Harry Gordon, Judith Newton, Shuna Colville, Suvankar Pal, Siddharthan Chandran & Sharon Abrahams. (2020) Reliability and validity of the brief dimensional apathy scale. Archives of Clinical Neuropsychology 35:5, pages 539-544.
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Lise M’Barek, Ratko Radakovic, Malika Noquet, Alexandre Laurent & Philippe Allain. (2018) Different aspects of emotional processes in apathy: Application of the French translated dimensional apathy scale. Current Psychology 39:2, pages 564-570.
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S. Raimo, L. Trojano, M. Gaita, D. Spitaleri & G. Santangelo. (2020) Assessing apathy in multiple sclerosis: Validation of the dimensional apathy scale and comparison with apathy evaluation scale. Multiple Sclerosis and Related Disorders 38, pages 101870.
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Paramita Chaudhuri, Kailash P. Prajapati, Bibin G. Anand, Kriti Dubey & Karunakar Kar. (2019) Amyloid cross-seeding raises new dimensions to understanding of amyloidogenesis mechanism. Ageing Research Reviews 56, pages 100937.
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Mattia Siciliano, Luigi Trojano, Francesca Trojsi, Maria Rosaria Monsurrò, Gioacchino Tedeschi & Gabriella Santangelo. (2019) Assessing anxiety and its correlates in amyotrophic lateral sclerosis: The state‐trait anxiety inventory. Muscle & Nerve 60:1, pages 47-55.
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Monica Consonni, Stefano F Cappa, Eleonora Dalla Bella, Valeria Elisa Contarino & Giuseppe Lauria. (2019) Cortical correlates of behavioural change in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery & Psychiatry 90:4, pages 380-386.
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Jashelle Caga, Sharpley Hsieh, Patricia Lillo, Kaitlin Dudley & Eneida Mioshi. (2019) The Impact of Cognitive and Behavioral Symptoms on ALS Patients and Their Caregivers. Frontiers in Neurology 10.
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Ratko Radakovic & Sharon Abrahams. (2018) Multidimensional apathy: evidence from neurodegenerative disease. Current Opinion in Behavioral Sciences 22, pages 42-49.
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Ratko Radakovic, Laura Stephenson, Judith Newton, Christopher Crockford, Robert Swingler, Siddharthan Chandran & Sharon Abrahams. (2017) Multidimensional apathy and executive dysfunction in amyotrophic lateral sclerosis. Cortex 94, pages 142-151.
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Gabriella Santangelo, Alfonsina D’Iorio, Fausta Piscopo, Sofia Cuoco, Katia Longo, Marianna Amboni, Chiara Baiano, Domenico Tafuri, Maria Teresa Pellecchia, Paolo Barone & Carmine Vitale. (2017) Assessment of apathy minimising the effect of motor dysfunctions in Parkinson’s disease: a validation study of the dimensional apathy scale. Quality of Life Research 26:9, pages 2533-2540.
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