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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 45, 2017 - Issue 4
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Articles

RETRACTED ARTICLE: The effect of safranal loaded mucoadhesive nanoemulsion on oxidative stress markers in cerebral ischemia

Niyaz AhmadDepartment of Pharmaceutics, College of Clinical Pharmacy, Dammam University, Dammam, Kingdom of Saudi Arabia; Correspondence[email protected]
,
Rizwan AhmadDepartment of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Dammam University, Dammam, Kingdom of Saudi Arabia;
,
Atta Abbas NaqviDepartment of Pharmacy Practice, College of Clinical Pharmacy, University of Dammam, Dammam, Kingdom of Saudi Arabia;
,
Mohammad AshafaqNeuroscience and Toxicology Unit, College of Pharmacy, Jazan University, Jazan, Kingdom of Saudi Arabia;
,
Md Aftab AlamDepartment of Pharmaceutics, School of Medical and Allied Sciences, Galgotias University, Gautam Budh Nagar, Greater, Noida, India;
,
Farhan Jalees AhmadNanomedicine Lab, Department of Pharmaceutics, Faculty of Pharmacy, Hamdard Nagar, Jamia Hamdard, New Delhi, India;
&
Mastour Safer Al-GhamdiDepartment of Pharmacology, College of Clinical Pharmacy, University of Dammam, Dammam, Kingdom of Saudi Arabia
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Pages 775-787 | Received 02 Jun 2016, Accepted 22 Aug 2016, Published online: 09 Sep 2016

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Asmaa S. Shahat, Wafaa A. Hassan & Wael M. El-Sayed. (2022) N-Acetylcysteine and Safranal prevented the brain damage induced by hyperthyroidism in adult male rats. Nutritional Neuroscience 25:2, pages 231-245.
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Jia Liu, Lei Chen, Xin Zhang, Lixiao Pan & Lili Jiang. (2020) The Protective Effects of Juglanin in Cerebral Ischemia Reduce Blood–Brain Barrier Permeability via Inhibition of VEGF/VEGFR2 Signaling. Drug Design, Development and Therapy 14, pages 3165-3175.
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Minjuan Wang, Chengliang Li & Wei Shi. (2020) Stomatin-like protein-2 confers neuroprotection effect in oxygen-glucose deprivation/reoxygenation-injured neurons by regulating AMPK/Nrf2 signalling. Journal of Drug Targeting 28:6, pages 600-608.
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Amit Alexander, Mukta Agrawal, Ajaz Uddin, Sabahuddin Siddique, Ahmed M Shehata, Mahmoud A Shaker, Syed Ata Ur Rahman, Mohi Iqbal M Abdul & Mohamed A Shaker. (2019) Recent expansions of novel strategies towards the drug targeting into the brain. International Journal of Nanomedicine 14, pages 5895-5909.
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Niyaz Ahmad, Abeer M. Al-Subaie, Rizwan Ahmad, Sonali Sharma, Md Aftab Alam, Mohammad Ashafaq, Rehan Abdur Rub & Farhan Jalees Ahmad. (2019) RETRACTED ARTICLE: Brain-targeted glycyrrhizic-acid-loaded surface decorated nanoparticles for treatment of cerebral ischaemia and its toxicity assessment. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 475-490.
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Niyaz Ahmad, Rizwan Ahmad, Md Aftab Alam, Farhan Jalees Ahmad & Mohd Amir. (2018) RETRACTED ARTICLE: Impact of ultrasonication techniques on the preparation of novel Amiloride-nanoemulsion used for intranasal delivery in the treatment of epilepsy. Artificial Cells, Nanomedicine, and Biotechnology 46:sup3, pages 192-207.
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Guoping Wang, Yuanbo Wu & Yuyou Zhu. (2018) RETRACTED ARTICLE: Mechanism of MALAT1 preventing apoptosis of vascular endothelial cells induced by oxygen–glucose deficiency and reoxidation. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 798-805.
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Imran Khan, Ashutosh Bahuguna, Monika Bhardwaj, Tejinder Pal Khaket & Sun Chul Kang. (2018) Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 664-675.
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Niyaz Ahmad, Rizwan Ahmad, Atta Abbas Naqvi, Md Aftab Alam, Mohammad Ashafaq, Rehan Abdur Rub & Farhan Jalees Ahmad. (2018) RETRACTED ARTICLE: Intranasal delivery of quercetin-loaded mucoadhesive nanoemulsion for treatment of cerebral ischaemia. Artificial Cells, Nanomedicine, and Biotechnology 46:4, pages 717-729.
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Niyaz Ahmad. (2017) Rasagiline-encapsulated chitosan-coated PLGA nanoparticles targeted to the brain in the treatment of parkinson's disease. Journal of Liquid Chromatography & Related Technologies 40:13, pages 677-690.
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Niyaz Ahmad, Rizwan Ahmad, Atta Abbas Naqvi, Md Aftab Alam, Mohammad Ashafaq, Zeenat Iqbal & Farhan Jalees Ahmad. (2017) Isolation, characterization, and quantification of curcuminoids and their comparative effects in cerebral ischemia. Journal of Liquid Chromatography & Related Technologies 40:3, pages 133-146.
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Articles from other publishers (27)

Nagwa Ibrahim Shehata, Dina Mohamed Abd EL-Salam, Roqaya Mahmoud Hussein & Sherine Maher Rizk. (2023) Effect of safranal or candesartan on 3-nitropropionicacid-induced biochemical, behavioral and histological alterations in a rat model of Huntington’s disease. PLOS ONE 18:11, pages e0293660.
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Shashi Kiran Misra & Kamla Pathak. (2023) Nose-to-Brain Targeting via Nanoemulsion: Significance and Evidence. Colloids and Interfaces 7:1, pages 23.
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Mohamad Taleuzzaman, Sanjay Chauhan, Devendra Singh Tomar, Pankaj Kumar Singh, Isha Talwar & Md Noushad Javed. 2022. Nanotechnology in Functional Foods. Nanotechnology in Functional Foods 161 191 .
Mohammad Imran, Ajay Kumar, Akshay Vyawahare, Puspita Saha, Anas Ahmad, Md. Meraj Ansari, Rakesh Kumar Mishra, Aneesh Ali, Abdul Quaiyoom Khan & Rehan Khan. 2022. Regenerative Therapies in Ischemic Stroke Recovery. Regenerative Therapies in Ischemic Stroke Recovery 53 83 .
Md Shahidul Islam, Fazli Azim, Hedaeytullah Saju, Arman Zargaran, Meysam Shirzad, Mostofa Kamal, Kaniz Fatema, Sumbul Rehman, M.A. Momith Azad & Somayeh Ebrahimi-Barough. (2021) Pesticides and Parkinson’s disease: Current and future perspective. Journal of Chemical Neuroanatomy 115, pages 101966.
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Ahmad Fotoohi, Mohammad Raman Moloudi, Saed Hosseini, Kambiz Hassanzadeh, Marco Feligioni & Esmael Izadpanah. (2021) A Novel Pharmacological Protective Role for Safranal in an Animal Model of Huntington’s Disease. Neurochemical Research 46:6, pages 1372-1379.
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Fatemeh Forouzanfar, Elham Asadpour, Hossein Hosseinzadeh, Mohammad Taher Boroushaki, Afrouz Adab, Seyedeh Hoda Dastpeiman & Hamid R. Sadeghnia. (2020) Safranal protects against ischemia-induced PC12 cell injury through inhibiting oxidative stress and apoptosis. Naunyn-Schmiedeberg's Archives of Pharmacology 394:4, pages 707-716.
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Waleed H. Almalki, Saad Alghamdi, Abdulaziz Alzahrani & Wenzhi Zhang. (2021) Emerging paradigms in treating cerebral infarction with nanotheranostics: opportunities and clinical challenges. Drug Discovery Today 26:3, pages 826-835.
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Niyaz Ahmad, Rizwan Ahmad, Mohd Amir, Md Aftab Alam, Mortaja Zaki Almakhamel, Abuzer Ali, Ayaz Ahmad & Kamran Ashraf. (2021) Ischemic brain treated with 6-gingerol loaded mucoadhesive nanoemulsion via intranasal delivery and their comparative pharmacokinetic effect in brain. Journal of Drug Delivery Science and Technology 61, pages 102130.
Crossref
Oznur Saroglu, Hatice Bekiroglu & Ayse Karadag. 2021. Saffron. Saffron 183 220 .
Elwira Lasoń. (2020) Topical Administration of Terpenes Encapsulated in Nanostructured Lipid-Based Systems. Molecules 25:23, pages 5758.
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Niyaz Ahmad, Rizwan Ahmad, Sadiq Al Qatifi, Mahdi Alessa, Hassan Al Hajji & Md Sarafroz. (2020) A bioanalytical UHPLC based method used for the quantification of Thymoquinone-loaded-PLGA-nanoparticles in the treatment of epilepsy. BMC Chemistry 14:1.
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Huang-Ping Yu, Fu-Chao Liu, Cheng-Yu Lin, Ani Umoro, Jiří Trousil, Tsong-Long Hwang & Jia-You Fang. (2020) Suppression of neutrophilic inflammation can be modulated by the droplet size of anti-inflammatory nanoemulsions. Nanomedicine 15:8, pages 773-791.
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Zi-Qi Liu, Na Liu, Si-Si Huang, Miao-Miao Lin, Shu Qin, Jun-Chao Wu, Zhong-Qin Liang, Zheng-Hong Qin & Yan Wang. (2020) NADPH protects against kainic acid-induced excitotoxicity via autophagy-lysosome pathway in rat striatum and primary cortical neurons. Toxicology 435, pages 152408.
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Saeideh Nozohouri, Ali Ehsan Sifat, Bhuvaneshwar Vaidya & Thomas J. Abbruscato. (2020) Novel approaches for the delivery of therapeutics in ischemic stroke. Drug Discovery Today 25:3, pages 535-551.
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Niyaz Ahmad, Rizwan Ahmad, Ridha Alrasheed, Hassan Almatar, Abdullah Al-Ramadan, Mohd Amir & Md Sarafroz. (2020) Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy. Pharmaceutics 12:3, pages 203.
Crossref
Niyaz Ahmad, Rizwan Ahmad, Farhan Jalees Ahmad, Wasim Ahmad, Md Aftab Alam, Mohd Amir & Abuzer Ali. (2020) Poloxamer-chitosan-based Naringenin nanoformulation used in brain targeting for the treatment of cerebral ischemia. Saudi Journal of Biological Sciences 27:1, pages 500-517.
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Amin Mokhtari-Zaer, Saeideh Saadat, Vahideh Ghorani, Arghavan Memarzia & Mohammad Hossein Boskabady. 2020. Saffron. Saffron 193 217 .
Saeed Samarghandian & Tahereh Farkhondeh. 2020. Saffron. Saffron 103 116 .
Elaheh Mirhadi, Hooriyeh Nassirli & Bizhan Malaekeh-Nikouei. (2019) An updated review on therapeutic effects of nanoparticle-based formulations of saffron components (safranal, crocin, and crocetin). Journal of Pharmaceutical Investigation 50:1, pages 47-58.
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Niyaz Ahmad, Rizwan Ahmad, Md Aftab Alam, Farhan Jalees Ahmad & Rehan Abdur Rub. (2019) Quantification and Evaluation of Glycyrrhizic Acid-loaded Surface Decorated Nanoparticles by UHPLC-MS/MS and used in the Treatment of Cerebral Ischemia. Current Pharmaceutical Analysis 16:1, pages 24-39.
Crossref
Tourandokht Baluchnejadmojarad, Seyed-Mahdi Mohamadi-Zarch & Mehrdad Roghani. (2019) Safranal, an active ingredient of saffron, attenuates cognitive deficits in amyloid β-induced rat model of Alzheimer’s disease: underlying mechanisms. Metabolic Brain Disease 34:6, pages 1747-1759.
Crossref
Faye Bolan, Irene Louca, Calvin Heal & Catriona J. Cunningham. (2019) The Potential of Biomaterial-Based Approaches as Therapies for Ischemic Stroke: A Systematic Review and Meta-Analysis of Pre-clinical Studies. Frontiers in Neurology 10.
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Zahra Karami, Mohammad Reza Saghatchi Zanjani & Mehrdad Hamidi. (2019) Nanoemulsions in CNS drug delivery: recent developments, impacts and challenges. Drug Discovery Today 24:5, pages 1104-1115.
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Sathyasivam Kaviarasi, Eiji Yuba, Atsushi Harada & Uma Maheswari Krishnan. (2019) Emerging paradigms in nanotechnology for imaging and treatment of cerebral ischemia. Journal of Controlled Release 300, pages 22-45.
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Telma Bezerra Soares, Luís Loureiro, Ana Carvalho, Maria Elisabete C.D. Real Oliveira, Alberto Dias, Bruno Sarmento & Marlene Lúcio. (2018) Lipid nanocarriers loaded with natural compounds: Potential new therapies for age related neurodegenerative diseases?. Progress in Neurobiology 168, pages 21-41.
Crossref
Kumud Madan & Sanju Nanda. (2018) In-vitro evaluation of antioxidant, anti-elastase, anti-collagenase, anti-hyaluronidase activities of safranal and determination of its sun protection factor in skin photoaging. Bioorganic Chemistry 77, pages 159-167.
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