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Study of the effects of polymerized porcine hemoglobin (pPolyHb) in an acute anemia rat model

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Pages 694-700 | Received 01 Aug 2016, Accepted 22 Aug 2016, Published online: 09 Dec 2016

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Hitomi Iwasaki, Kyoko Yokomaku, Moeka Kureishi, Keisuke Igarashi, Ryo Hashimoto, Mitsutomo Kohno, Masayuki Iwazaki, Risa Haruki, Motofusa Akiyama, Kenichi Asai, Yuka Nakamura, Ryosuke Funaki, Yoshitsugu Morita & Teruyuki Komatsu. (2018) Hemoglobin–albumin cluster: physiological responses after exchange transfusion into rats and blood circulation persistence in dogs. Artificial Cells, Nanomedicine, and Biotechnology 46:sup3, pages 621-629.
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Yuesheng Shen, Wenjin Zhu, Mengye Zhao, Guige Zhao, Geng Niu, Yuwei Bai, Bo Yang, Chao Chen & Hongli Zhu. (2018) Study of the pharmacokinetics of polymerized porcine hemoglobin (pPolyHb). Artificial Cells, Nanomedicine, and Biotechnology 46:7, pages 1373-1379.
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Articles from other publishers (4)

Wataru Okamoto, Yuuki Hiwatashi, Tatsuhiro Kobayashi, Yoshitsugu Morita, Hiroto Onozawa, Masayuki Iwazaki, Mitsutomo Kohno, Hirotaka Tomiyasu, Ryota Tochinai, Radostina Georgieva, Hans Bäumler & Teruyuki Komatsu. (2023) Poly(2-ethyl-2-oxazoline)-Conjugated Hemoglobins as a Red Blood Cell Substitute. ACS Applied Bio Materials.
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Wataru Okamoto, Mai Hasegawa, Tomone Usui, Tomonori Kashima, Sho Sakata, Tatsuhiko Hamano, Hiroto Onozawa, Ryo Hashimoto, Masayuki Iwazaki, Mitsutomo Kohno & Teruyuki Komatsu. (2022) Hemoglobin–albumin clusters as an artificial O 2 carrier: Physicochemical properties and resuscitation from hemorrhagic shock in rats . Journal of Biomedical Materials Research Part B: Applied Biomaterials 110:8, pages 1827-1838.
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Alexander T. Williams, Cynthia R. Muller, Allyn M. Eaker, Donald A. Belcher, Crystal Bolden-Rush, Andre F. Palmer & Pedro Cabrales. (2020) Polymerized Hemoglobin With Increased Molecular Size Reduces Toxicity in Healthy Guinea Pigs. ACS Applied Bio Materials 3:5, pages 2976-2985.
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Yuxiao Tang, Ruirui Qi, Huiwen Wu, Wencai Shi, Yan Xu & Min Li. (2019) Reduction of hemoglobin, not iron, inhibited maturation of red blood cells in male rats exposed to high intensity endurance exercises. Journal of Trace Elements in Medicine and Biology 52, pages 263-269.
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