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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 45, 2017 - Issue 4
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Study of the effects of polymerized porcine hemoglobin (pPolyHb) in an acute anemia rat model

Huifang LiuCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China;
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Chengbin YanCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China;
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Kunping YanCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China;
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Wenjin ZhuSchool of public health, The First Affiliated Hospital of Xi’ an Jiaotong University, Xi’an, PR China
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Yuesheng ShenCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China;
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Bo YangCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China;
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Chao ChenCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China;
&
Hongli ZhuCollege of Life Science, Northwest University, Xi’an, PR China; ;National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi’an, PR China; Correspondence[email protected]
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Pages 694-700 | Received 01 Aug 2016, Accepted 22 Aug 2016, Published online: 09 Dec 2016

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Hitomi Iwasaki, Kyoko Yokomaku, Moeka Kureishi, Keisuke Igarashi, Ryo Hashimoto, Mitsutomo Kohno, Masayuki Iwazaki, Risa Haruki, Motofusa Akiyama, Kenichi Asai, Yuka Nakamura, Ryosuke Funaki, Yoshitsugu Morita & Teruyuki Komatsu. (2018) Hemoglobin–albumin cluster: physiological responses after exchange transfusion into rats and blood circulation persistence in dogs. Artificial Cells, Nanomedicine, and Biotechnology 46:sup3, pages 621-629.
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Chen Guo & Thomas Ming Swi Chang. (2018) Long term safety and immunological effects of a nanobiotherapeutic, bovine poly-[hemoglobin-catalase-superoxide dismutase-carbonic anhydrase], after four weekly 5% blood volume top-loading followed by a challenge of 30% exchange transfusion. Artificial Cells, Nanomedicine, and Biotechnology 46:7, pages 1349-1363.
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Yuesheng Shen, Wenjin Zhu, Mengye Zhao, Guige Zhao, Geng Niu, Yuwei Bai, Bo Yang, Chao Chen & Hongli Zhu. (2018) Study of the pharmacokinetics of polymerized porcine hemoglobin (pPolyHb). Artificial Cells, Nanomedicine, and Biotechnology 46:7, pages 1373-1379.
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Articles from other publishers (4)

Wataru Okamoto, Yuuki Hiwatashi, Tatsuhiro Kobayashi, Yoshitsugu Morita, Hiroto Onozawa, Masayuki Iwazaki, Mitsutomo Kohno, Hirotaka Tomiyasu, Ryota Tochinai, Radostina Georgieva, Hans Bäumler & Teruyuki Komatsu. (2023) Poly(2-ethyl-2-oxazoline)-Conjugated Hemoglobins as a Red Blood Cell Substitute. ACS Applied Bio Materials.
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Wataru Okamoto, Mai Hasegawa, Tomone Usui, Tomonori Kashima, Sho Sakata, Tatsuhiko Hamano, Hiroto Onozawa, Ryo Hashimoto, Masayuki Iwazaki, Mitsutomo Kohno & Teruyuki Komatsu. (2022) Hemoglobin–albumin clusters as an artificial O 2 carrier: Physicochemical properties and resuscitation from hemorrhagic shock in rats . Journal of Biomedical Materials Research Part B: Applied Biomaterials 110:8, pages 1827-1838.
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Alexander T. Williams, Cynthia R. Muller, Allyn M. Eaker, Donald A. Belcher, Crystal Bolden-Rush, Andre F. Palmer & Pedro Cabrales. (2020) Polymerized Hemoglobin With Increased Molecular Size Reduces Toxicity in Healthy Guinea Pigs. ACS Applied Bio Materials 3:5, pages 2976-2985.
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Yuxiao Tang, Ruirui Qi, Huiwen Wu, Wencai Shi, Yan Xu & Min Li. (2019) Reduction of hemoglobin, not iron, inhibited maturation of red blood cells in male rats exposed to high intensity endurance exercises. Journal of Trace Elements in Medicine and Biology 52, pages 263-269.
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