Advanced search
Publication Cover
Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 46, 2018 - Issue 7
Submit an article Journal homepage
2,358
Views
40
CrossRef citations to date
0
Altmetric
Original Articles

Enhancement of anticancer activity by silibinin and paclitaxel combination on the ovarian cancer

Fatima Pashaei-AslMolecular Biology Laboratory, Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;
,
Roghiyeh Pashaei-AslDepartment of Anatomy, Medical School, Iran University of Medical Science, Tehran, Iran; ;Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran;
,
Khodadad KhodadadiGenetic Research Theme, Murdoch Children's Research Institute, Royal Children's Hospital, The University of Melbourne, Melbourne, Australia;
,
Abolfazl AkbarzadehDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; ;Universal Scientific Education and Research Network (USERN), Tabriz, Iran;
,
Esmaeil EbrahimieInstitute of Biotechnology, Shiraz University, Shiraz, Iran; ;School of Medicine, The University of Adelaide, Adelaide, Australia;
&
Maryam PashaiaslDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; ;Women's Reproductive Health Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran; ;Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, IranCorrespondence[email protected]
Pages 1483-1487 | Received 22 Apr 2017, Accepted 28 Aug 2017, Published online: 08 Sep 2017

Citations (40)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Prabha Tiwari & Kaushala Prasad Mishra. (2023) Role of Plant-Derived Flavonoids in Cancer Treatment. Nutrition and Cancer 75:2, pages 430-449.
Read now
Arjun Patra, Swaha Satpathy, Pradeep K. Naik, Mohsin Kazi & Muhammad Delwar Hussain. (2022) Folate receptor-targeted PLGA-PEG nanoparticles for enhancing the activity of genistein in ovarian cancer. Artificial Cells, Nanomedicine, and Biotechnology 50:1, pages 228-239.
Read now
Meghanath B. Shete, Ashwini S. Deshpande & Pravin Shende. (2022) Silybin-based herbal nanocarriers: an advancement in anticancer therapy. Materials Technology 37:13, pages 2832-2852.
Read now
Zhichun Yang, Qionghui Pan, Dingfang Zhang, Jianqiang Chen, Yinda Qiu, Xiaojing Chen, Feiyun Zheng & Feng Lin. (2019) Silibinin restores the sensitivity of cisplatin and taxol in A2780-resistant cell and reduces drug-induced hepatotoxicity. Cancer Management and Research 11, pages 7111-7122.
Read now
Xin Jin, Jianping Zhou, Zhenhai Zhang & Huixia Lv. (2018) The combined administration of parthenolide and ginsenoside CK in long circulation liposomes with targeted tLyp-1 ligand induce mitochondria-mediated lung cancer apoptosis. Artificial Cells, Nanomedicine, and Biotechnology 46:sup3, pages 931-942.
Read now

Articles from other publishers (35)

Rohan Ghadi, Pawan Kumar Pandey, Akash Gabhale, Aaradhya Wadikar, M. Dharshini, Kaushik Kuche, Tushar Date & Sanyog Jain. (2023) Genipin-crosslinked albumin nanoparticles containing neratinib and silibinin: A dual-death therapy for triple negative breast cancer. International Journal of Pharmaceutics 648, pages 123570.
Crossref
Elnaz Salmani-Javan, Davoud Jafari-Gharabaghlou, Esat Bonabi & Nosratollah Zarghami. (2023) Fabricating niosomal-PEG nanoparticles co-loaded with metformin and silibinin for effective treatment of human lung cancer cells. Frontiers in Oncology 13.
Crossref
Aisha Nawaz, Sumera Zaib, Imtiaz Khan, Abrar Ahmed, Kiran Shahzadi & Huma Riaz. (2023) Silybum marianum: An Overview of its Phytochemistry and Pharmacological Activities with Emphasis on Potential Anticancer Properties. Anti-Cancer Agents in Medicinal Chemistry 23:13, pages 1519-1534.
Crossref
Hemlata Bhardwaj, Neeru Vasudeva & Sunil Sharma. (2023) Possible Mechanism and Pharmacological Activities of a Flavolignan Silibinin. Current Bioactive Compounds 19:7.
Crossref
Trang Thi Thu Nguyen, Bao Quang Gia Le, Vy Tran Hanh Nguyen, Jae‐Hyoung Lee, Ngoc Xuan Dat Mai, Linh Ho Thuy Nguyen & Tan Le Hoang Doan. (2023) Microwave‐Assisted Synthesis of Porous Biomolecule‐Incorporated Metal‐Organic Frameworks as Efficient Nanocarriers for Anti‐Cancer Drugs. ChemistrySelect 8:25.
Crossref
Md Sohel, Suraiya Aktar, Partha Biswas, Md. Al Amin, Md. Arju Hossain, Nasim Ahmed, Md. Imrul Hasan Mim, Farhadul Islam & Abdullah Al Mamun. (2023) Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: A comprehensive review. Cancer Medicine 12:13, pages 14556-14583.
Crossref
Ghulam Mustafa, Dilawar Hassan, Gustavo Ruiz-Pulido, Mehrab Pourmadadi, Mohammad Mahdi Eshaghi, Razieh Behzadmehr, Fatemeh Soltani Tehrani, Abbas Rahdar, Dora Iliana Medina & Sadanand Pandey. (2023) Nanoscale drug delivery systems for cancer therapy using paclitaxel— A review of challenges and latest progressions. Journal of Drug Delivery Science and Technology 84, pages 104494.
Crossref
Chaithanya Chelakkot, Vipin Shankar Chelakkot, Youngkee Shin & Kyoung Song. (2023) Modulating Glycolysis to Improve Cancer Therapy. International Journal of Molecular Sciences 24:3, pages 2606.
Crossref
Kapish Kapoor, Priyal Jain & Joohee Pradhan. 2023. Bioprospecting of Tropical Medicinal Plants. Bioprospecting of Tropical Medicinal Plants 767 788 .
Eshita Sharma, Dharam Chand Attri, Priyanka Sati, Praveen Dhyani, Agnieszka Szopa, Javad Sharifi-Rad, Christophe Hano, Daniela Calina & William C. Cho. (2022) Recent updates on anticancer mechanisms of polyphenols. Frontiers in Cell and Developmental Biology 10.
Crossref
Zahra Shakoori, Roghiyeh Pashaei-Asl, Maryam Pashaiasl, Soodabeh Davaran, Hossein Ghanbari, Esmaeil Ebrahimie & Seyed Mahdi Rezayat. (2022) Biocompatibility study of P (N-isopropylacrylamide)-based nanocomposite and its cytotoxic effect on HeLa cells as a drug delivery system for Cisplatin. Journal of Drug Delivery Science and Technology 71, pages 103254.
Crossref
Saeed Tavakoli, Farahnaz Khalighi-Sigaroodi, Reza Hagiaghaee, Mahdi Yaghoobi & Reza Ghafarzadegan. (2022) Purification, identification, and standardization of silybin A & B composition from Silybum marianum (L.) Gaertn. . Journal of Medicinal Plants 21:81, pages 1-11.
Crossref
Cláudia Pinto, Honorina Cidade, Madalena Pinto & Maria Elizabeth Tiritan. (2021) Chiral Flavonoids as Antitumor Agents. Pharmaceuticals 14:12, pages 1267.
Crossref
Hardeep Singh Tuli, Sonam Mittal, Diwakar Aggarwal, Gaurav Parashar, Nidarshana Chaturvedi Parashar, Sushil Kumar Upadhyay, Tushar Singh Barwal, Aklank Jain, Ginpreet Kaur, Raj Savla, Katrin Sak, Manoj Kumar, Mehmet Varol, Ashif Iqubal & Anil Kumar Sharma. (2021) Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance. Seminars in Cancer Biology 73, pages 196-218.
Crossref
Meirong Huo, Honglan Wang, Lingchao Li, Yuqing Tong, Chengxia Hu, Yongwei Gu, Jiyong Liu & Tingjie Yin. (2021) Redox-sensitive hyaluronic acid-cholesterol nanovehicles potentiate efficient transmembrane internalization and controlled release for penetrated “full-line” inhibition of pre-metastatic initiation. Journal of Controlled Release 336, pages 89-104.
Crossref
Pooja Rathaur, Mehul N. Soni, Brijesh Gelat, Rakesh Rawal, Himanshu A. Pandya & Kaid Johar. (2021) Network pharmacology-based evaluation of natural compounds with paclitaxel for the treatment of metastatic breast cancer. Toxicology and Applied Pharmacology 423, pages 115576.
Crossref
Qiaobin Hu, Yingjian Lu & Yangchao Luo. (2021) Recent advances in dextran-based drug delivery systems: From fabrication strategies to applications. Carbohydrate Polymers 264, pages 117999.
Crossref
Hend M. Nawara, Said M. Afify, Ghmkin Hassan, Maram H. Zahra, Akimasa Seno & Masaharu Seno. (2021) Paclitaxel-Based Chemotherapy Targeting Cancer Stem Cells from Mono- to Combination Therapy. Biomedicines 9:5, pages 500.
Crossref
Sidharth Mehan, Saloni Rahi, Shubham Upadhayay & Andleeb Khan. 2021. Polyphenols-based Nanotherapeutics for Cancer Management. Polyphenols-based Nanotherapeutics for Cancer Management 95 141 .
Farhad Soleimani, Rasoul Sharifi, Minoo Mahmoodi & Seyed Mehrdad Kassaee. (2020) The effects of silibinin on oxidative stress and microRNA-10b expression in animal models of breast cancer. Turkish Journal of Biochemistry 45:6, pages 707-713.
Crossref
Suyan Xu, Hongyan Zhang, Aifeng Wang, Yongcheng Ma, Yuan Gan & Guofeng Li. (2020) Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1. Cellular & Molecular Biology Letters 25:1.
Crossref
Kalpana Tilekar, Neha Upadhyay, Cristina V. Iancu, Vadim Pokrovsky, Jun-yong Choe & C.S. Ramaa. (2020) Power of two: combination of therapeutic approaches involving glucose transporter (GLUT) inhibitors to combat cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1874:2, pages 188457.
Crossref
Diana S. Antal, Florina Ardelean, Stefana Avram, Ioana Z. Pavel, Corina Danciu, Codruta Soica & Cristina Dehelean. (2020) Flavonolignans: One Step Further in the Broad-Spectrum Approach of Cancer. Anti-Cancer Agents in Medicinal Chemistry 20:15, pages 1817-1830.
Crossref
Zeinab Nouri, Sajad Fakhri, Keyvan Nouri, Carly E. Wallace, Mohammad Hosein Farzaei & Anupam Bishayee. (2020) Targeting Multiple Signaling Pathways in Cancer: The Rutin Therapeutic Approach. Cancers 12:8, pages 2276.
Crossref
Simona Dobiasová, Kateřina Řehořová, Denisa Kučerová, David Biedermann, Kristýna Káňová, Lucie Petrásková, Kamila Koucká, Radka Václavíková, Kateřina Valentová, Tomáš Ruml, Tomáš Macek, Vladimír Křen & Jitka Viktorová. (2020) Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential. Antioxidants 9:5, pages 455.
Crossref
Meirong Huo, Honglan Wang, Ying Zhang, Han Cai, Pan Zhang, Lingchao Li, Jianping Zhou & Tingjie Yin. (2020) Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation. Journal of Controlled Release 321, pages 198-210.
Crossref
Dominique Delmas, Jianbo Xiao, Anne Vejux & Virginie Aires. (2020) Silymarin and Cancer: A Dual Strategy in Both in Chemoprevention and Chemosensitivity. Molecules 25:9, pages 2009.
Crossref
Sara Rahbar, Maryam Pashaiasl, Maryam Ezzati, Yadollah Ahmadi AsrBadr, Manijeh Mohammadi‐Dehcheshmeh, Seyed Abolgasem Mohammadi & Marefat Ghaffari Novin. (2019) MicroRNA‐based regulatory circuit involved in sperm infertility. Andrologia 52:1.
Crossref
Fu Xiaomeng, Lv Lei, An Jinghong, Jiang Juan, Yue Qi & Yuan Dandan. (2020) Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway. Brazilian Journal of Medical and Biological Research 53:6.
Crossref
Hua Luo, Chi Teng Vong, Hanbin Chen, Yan Gao, Peng Lyu, Ling Qiu, Mingming Zhao, Qiao Liu, Zehua Cheng, Jian Zou, Peifen Yao, Caifang Gao, Jinchao Wei, Carolina Oi Lam Ung, Shengpeng Wang, Zhangfeng Zhong & Yitao Wang. (2019) Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine. Chinese Medicine 14:1.
Crossref
Tahereh Hosseinabadi, Zahra Lorigooini, Maryam Tabarzad, Bahare Salehi, Célia F. Rodrigues, Natália Martins & Javad Sharifi‐Rad. (2019) Silymarin antiproliferative and apoptotic effects: Insights into its clinical impact in various types of cancer. Phytotherapy Research 33:11, pages 2849-2861.
Crossref
Faramarz Rahmatizadeh, Shiva Gholizadeh-Ghaleh Aziz, Khodadad KhodadadiMaryam Lale AtaeiEsmaeil EbrahimieJafar Soleimani RadMaryam Pashaiasl. (2019) Bidirectional and Opposite Effects of Naïve Mesenchymal Stem Cells Ontumor Growth and Progression. Advanced Pharmaceutical Bulletin 9:4, pages 539-558.
Crossref
Weixiao An, Honglin Lai, Yangyang Zhang, Minghua Liu, Xiukun Lin & Shousong Cao. (2019) Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese Medicines. Frontiers in Pharmacology 10.
Crossref
Shiva Gholizadeh‐Ghaleh Aziz, Zahra Fardyazar & Maryam Pashaiasl. (2019) The human amniotic fluid mesenchymal stem cells therapy on, SKOV3, ovarian cancer cell line. Molecular Genetics & Genomic Medicine 7:7.
Crossref
Elina Abaev-Schneiderman, Lee Admoni-Elisha & Dan Levy. (2019) SETD3 is a positive regulator of DNA-damage-induced apoptosis. Cell Death & Disease 10:2.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.