Advanced search
Publication Cover
Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 46, 2018 - Issue sup3
Submit an article Journal homepage
6,368
Views
63
CrossRef citations to date
0
Altmetric
Original Articles

Novel alternatives to extracellular vesicle-based immunotherapy – exosome mimetics derived from natural killer cells

Liya ZhuDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Prakash GangadaranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Senthilkumar KalimuthuDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Ji Min OhDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Se Hwan BaekDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Shin Young JeongDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Sang-Woo LeeDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
,
Jaetae LeeDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaView further author information
&
Byeong-Cheol AhnDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South KoreaCorrespondence[email protected]
View further author information
 show all
Pages 166-179 | Received 06 Apr 2018, Accepted 05 Jun 2018, Published online: 09 Aug 2018

Citations (63)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Ting Huyan, Hongduo Li, Hourong Peng, Jinzhao Chen, Ruixin Yang, Wei Zhang & Qi Li. (2020) Extracellular Vesicles – Advanced Nanocarriers in Cancer Therapy: Progress and Achievements. International Journal of Nanomedicine 15, pages 6485-6502.
Read now
Chun-Hua Wu, Jingbo Li, Li Li, Jianping Sun, Muller Fabbri, Alan S. Wayne, Robert C. Seeger & Ambrose Y. Jong. (2019) Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells. Journal of Extracellular Vesicles 8:1.
Read now

Articles from other publishers (61)

Lianghui Huang, Enguang Wu, Jiawei Liao, Zongyi Wei, Jin Wang & Zhenhua Chen. (2023) Research Advances of Engineered Exosomes as Drug Delivery Carrier. ACS Omega 8:46, pages 43374-43387.
Crossref
Ting Feng, Yilin Wan, Shengsheng Cui & Yanlei Liu. (2023) The Role of Extracellular Vesicles in Tumor Therapy and Imaging. Advanced Therapeutics.
Crossref
Zahra Hatami, Zahra Sadat Hashemi, Mohamad Eftekhary, Ala Amiri, Vahid Karpisheh, Kaveh Nasrollahi & Reza Jafari. (2023) Natural killer cell-derived exosomes for cancer immunotherapy: innovative therapeutics art. Cancer Cell International 23:1.
Crossref
Yu Long, Nannan Wei, Peizhe Yuan, Xiaoying Lv, Xiangming Song, Ziyang Zhu, Qingyao Liu, Dawei Jiang, Xiaoli Lan & Yongkang Gai. (2023) NIRF/PET imaging of γδ T cells via metabolic glycoengineering and bioorthogonal labeling. Chemical Engineering Journal 470, pages 144127.
Crossref
Ana Macedo-Pereira, Cláudia Martins, Jorge Lima & Bruno Sarmento. (2023) Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?. Journal of Controlled Release 358, pages 98-115.
Crossref
Nazira El-Hage, Matthew J. Haney, Yuling Zhao, Myosotys Rodriguez, Zhanhong Wu, Mori Liu, Carson J. Swain, Hong Yuan & Elena V. Batrakova. (2023) Extracellular Vesicles Released by Genetically Modified Macrophages Activate Autophagy and Produce Potent Neuroprotection in Mouse Model of Lysosomal Storage Disorder, Batten Disease. Cells 12:11, pages 1497.
Crossref
David W. Greening, Rong Xu, Anukreity Ale, Christoph E. Hagemeyer & Weisan Chen. (2023) Extracellular vesicles as next generation immunotherapeutics. Seminars in Cancer Biology 90, pages 73-100.
Crossref
Endong Zhang, Philana Phan & Zongmin Zhao. (2023) Cellular nanovesicles for therapeutic immunomodulation: A perspective on engineering strategies and new advances. Acta Pharmaceutica Sinica B 13:5, pages 1789-1827.
Crossref
Yuchen Qi, Xiang Zhao, Yan Dong, Min Wang, Junyi Wang, Zhichao Fan, Qin Weng, Hua Yu & Jianjun Li. (2023) Opportunities and challenges of natural killer cell-derived extracellular vesicles. Frontiers in Bioengineering and Biotechnology 11.
Crossref
Alvin Man Lung Chan, Jin Min Cheah, Yogeswaran Lokanathan, Min Hwei Ng & Jia Xian Law. (2023) Natural Killer Cell-Derived Extracellular Vesicles as a Promising Immunotherapeutic Strategy for Cancer: A Systematic Review. International Journal of Molecular Sciences 24:4, pages 4026.
Crossref
Aun Raza, Gustavo Rodrigues Rossi, Taskeen Iqbal Janjua, Fernando Souza-Fonseca-Guimaraes & Amirali Popat. (2023) Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy. Trends in Biotechnology 41:1, pages 77-92.
Crossref
Raphael J. Crum, Héctor Capella-Monsonís, Jordan Chang, Marley J. Dewey, Brian D. Kolich, Kelsey T. Hall, Salma O. El-Mossier, David G. Nascari, George S. Hussey & Stephen F. Badylak. (2023) Biocompatibility and biodistribution of matrix-bound nanovesicles in vitro and in vivo. Acta Biomaterialia 155, pages 113-122.
Crossref
Matteo Moschetta, Martina Trevisani, Valentina Castagnola & Mattia Bramini. 2023. New Insights Into Glioblastoma. New Insights Into Glioblastoma 435 475 .
Hui‐Chong Lau, Dong Woo Han, Jinhee Park, Edwine Lehner, Carina Kals, Claudia Arzt, Elisabeth Bayer, Daniela Auer, Tanja Schally, Eva Grasmann, Han Fang, Jae‐Young Lee, Hyun Soo Lee, Jinah Han, Mario Gimona, Eva Rohde, Shingyu Bae & Seung Wook Oh. (2022) GMP‐compliant manufacturing of biologically active cell‐derived vesicles produced by extrusion technology. Journal of Extracellular Biology 1:12.
Crossref
Xiao‐Yu Zhu, Tian‐Yu Wang, Hao‐Ran Jia & Fu‐Gen Wu. (2022) Immunocyte‐Derived Nanodrugs for Cancer Therapy. Advanced Functional Materials 32:51.
Crossref
Antonia Reale, Tiffany Khong & Andrew Spencer. (2022) Extracellular Vesicles and Their Roles in the Tumor Immune Microenvironment. Journal of Clinical Medicine 11:23, pages 6892.
Crossref
Chongchao Hou, Qiang Wu, Lizhou Xu, Rongwei Cui, Rongying Ou, Danyang Li & Yunsheng Xu. (2022) Exploiting the potential of extracellular vesicles as delivery vehicles for the treatment of melanoma. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Akhil Srivastava, Shipra Rathore, Anupama Munshi & Rajagopal Ramesh. (2022) Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment. Seminars in Cancer Biology 86, pages 80-100.
Crossref
Ophélie Delcorte, Jonathan Degosserie & Christophe E. Pierreux. (2022) Role of Extracellular Vesicles in Thyroid Physiology and Diseases: Implications for Diagnosis and Treatment. Biomedicines 10:10, pages 2585.
Crossref
Yuan Du, Hongyi Wang, Yang Yang, Jianfeng Zhang, Yue Huang, Shunwu Fan, Chenhui Gu, Liqing Shangguan & Xianfeng Lin. (2022) Extracellular Vesicle Mimetics: Preparation from Top‐Down Approaches and Biological Functions. Advanced Healthcare Materials 11:19.
Crossref
Kewen Qian, Wenyan Fu, Tian Li, Jian Zhao, Changhai Lei & Shi Hu. (2022) The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy. Journal of Experimental & Clinical Cancer Research 41:1.
Crossref
Serena Lucotti, Candia M Kenific, Haiying Zhang & David Lyden. (2022) Extracellular vesicles and particles impact the systemic landscape of cancer. The EMBO Journal 41:18.
Crossref
Leili Shabani, Milad Abbasi, Masoomeh Amini, Ali Mohammad Amani & Ahmad Vaez. (2022) The brilliance of nanoscience over cancer therapy: Novel promising nanotechnology-based methods for eradicating glioblastoma. Journal of the Neurological Sciences 440, pages 120316.
Crossref
Xiaofeng Dai, Yongju Ye & Fule He. (2022) Emerging innovations on exosome-based onco-therapeutics. Frontiers in Immunology 13.
Crossref
Dolores Aguilar-Cazares, Rodolfo Chavez-Dominguez, Mario Marroquin-Muciño, Mario Perez-Medina, Jesus J. Benito-Lopez, Angel Camarena, Uriel Rumbo-Nava & Jose S. Lopez-Gonzalez. (2022) The systemic-level repercussions of cancer-associated inflammation mediators produced in the tumor microenvironment. Frontiers in Endocrinology 13.
Crossref
Xin-Chi Jiang, Tianyuan Zhang & Jian-Qing Gao. (2022) The in vivo fate and targeting engineering of crossover vesicle-based gene delivery system. Advanced Drug Delivery Reviews 187, pages 114324.
Crossref
Zahra Fekrirad, Amir Barzegar Behrooz, Shokoofeh Ghaemi, Arezou Khosrojerdi, Atefeh Zarepour, Ali Zarrabi, Ehsan Arefian & Saeid Ghavami. (2022) Immunology Meets Bioengineering: Improving the Effectiveness of Glioblastoma Immunotherapy. Cancers 14:15, pages 3698.
Crossref
Quan Liu, Xian Zhang & Jun Zhang. (2022) Exosome-Based Nanoplatforms: The Emerging Tools for Breast Cancer Therapy. Frontiers in Oncology 12.
Crossref
Yanan Zheng, Mei Li, Bowen Weng, Haijiao Mao & Jiyuan Zhao. (2022) Exosome-based delivery nanoplatforms: next-generation theranostic platforms for breast cancer. Biomaterials Science 10:7, pages 1607-1625.
Crossref
Ying-Yi Lin, Chung-Yi Chen, Dik-Lung Ma, Chung-Hang Leung, Chu-Yu Chang & Hui-Min David Wang. (2022) Cell-derived artificial nanovesicle as a drug delivery system for malignant melanoma treatment. Biomedicine & Pharmacotherapy 147, pages 112586.
Crossref
Lidija Filipović, Milica Kojadinović & Milica Popović. (2022) Exosomes and exosome-mimetics as targeted drug carriers: Where we stand and what the future holds?. Journal of Drug Delivery Science and Technology 68, pages 103057.
Crossref
Chunxiao Qi, Xiangsheng Liu, Dengke Zhi, Yifan Tai, Yufei Liu, Qiqi Sun, Kai Wang, Shufang Wang, Adam C. Midgley & Deling Kong. (2021) Exosome-mimicking nanovesicles derived from efficacy-potentiated stem cell membrane and secretome for regeneration of injured tissue. Nano Research 15:2, pages 1680-1690.
Crossref
Jing Wang, Motao Zhu & Guangjun Nie. (2021) Biomembrane-based nanostructures for cancer targeting and therapy: From synthetic liposomes to natural biomembranes and membrane-vesicles. Advanced Drug Delivery Reviews 178, pages 113974.
Crossref
Yi-Hsuan Ou, Jeremy Liang, Bertrand Czarny, Matthias G. Wacker, Victor Yu, Jiong-Wei Wang & Giorgia Pastorin. (2021) Extracellular Vesicle (EV) biohybrid systems for cancer therapy: Recent advances and future perspectives. Seminars in Cancer Biology 74, pages 45-61.
Crossref
Alice Grangier, Julien Branchu, Jeanne Volatron, Max Piffoux, Florence Gazeau, Claire Wilhelm & Amanda K.A. Silva. (2021) Technological advances towards extracellular vesicles mass production. Advanced Drug Delivery Reviews 176, pages 113843.
Crossref
Yong-Jiang Li, Jun-Yong Wu, Jihua Liu, Wenjie Xu, Xiaohan Qiu, Si Huang, Xiong-Bin Hu & Da-Xiong Xiang. (2021) Artificial exosomes for translational nanomedicine. Journal of Nanobiotechnology 19:1.
Crossref
Allyson M. Cochran & Jacki Kornbluth. (2021) Extracellular Vesicles From the Human Natural Killer Cell Line NK3.3 Have Broad and Potent Anti-Tumor Activity. Frontiers in Cell and Developmental Biology 9.
Crossref
Stephanie M. Kronstadt, Alex E. Pottash, Daniel Levy, Sheng Wang, Wei Chao & Steven M. Jay. (2021) Therapeutic Potential of Extracellular Vesicles for Sepsis Treatment. Advanced Therapeutics 4:7.
Crossref
Firoozeh Alavian & Sorayya Ghasemi. (2021) The Effectiveness of Nanoparticles on Gene Therapy for Glioblastoma Cells Apoptosis: A Systematic Review. Current Gene Therapy 21:3, pages 230-245.
Crossref
Feifeng Wu, Min Xie, Marady Hun, Zhou She, Cuifang Li, Senlin Luo, Xiaoyu Chen, Wuqing Wan, Chuan Wen & Jidong Tian. (2021) Natural Killer Cell-Derived Extracellular Vesicles: Novel Players in Cancer Immunotherapy. Frontiers in Immunology 12.
Crossref
Carolyn Marar, Bartholomew Starich & Denis Wirtz. (2021) Extracellular vesicles in immunomodulation and tumor progression. Nature Immunology 22:5, pages 560-570.
Crossref
Leila Pourtalebi Jahromi, Mohammad‐Ali Shahbazi, Aziz Maleki, Amir Azadi & Hélder A. Santos. (2021) Chemically Engineered Immune Cell‐Derived Microrobots and Biomimetic Nanoparticles: Emerging Biodiagnostic and Therapeutic Tools. Advanced Science 8:8.
Crossref
Heidi Schwarzenbach & Peter B. Gahan. (2021) Exosomes in Immune Regulation. Non-Coding RNA 7:1, pages 4.
Crossref
Fataneh Tavasolian, Ahmad Z. Hosseini, Mohsen Rashidi, Sara Soudi, Elham Abdollahi, Amir A. Momtazi-Borojeni, Thozhukat Sathyapalan & Amirhossein Sahebkar. (2021) The Impact of Immune Cell-derived Exosomes on Immune Response Initiation and Immune System Function. Current Pharmaceutical Design 27:2, pages 197-205.
Crossref
Ya-Ju Chang & Kuei-Chun Wang. 2021. Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases. Cellular Mechanotransduction Mechanisms in Cardiovascular and Fibrotic Diseases 255 277 .
Yi-Hsuan Ou, Shui Zou, Wei Jiang Goh, Jiong-Wei Wang, Matthias Wacker, Bertrand Czarny & Giorgia Pastorin. 2021. Bio-Carrier Vectors. Bio-Carrier Vectors 147 170 .
Kaixiang Feng, Runsheng Ma, Lele Zhang, Hongqiang Li, Yifeng Tang, Gongbo Du, Dongpeng Niu & Detao Yin. (2020) The Role of Exosomes in Thyroid Cancer and Their Potential Clinical Application. Frontiers in Oncology 10.
Crossref
Amirhossein Bahreyni, Yasir Mohamud & Honglin Luo. (2020) Emerging nanomedicines for effective breast cancer immunotherapy. Journal of Nanobiotechnology 18:1.
Crossref
Fanny A. Pelissier Vatter, Serena Lucotti & Haiying Zhang. (2020) Recent Advances in Experimental Models of Breast Cancer Exosome Secretion, Characterization and Function. Journal of Mammary Gland Biology and Neoplasia 25:4, pages 305-317.
Crossref
Xiwei Wang, Zheng XiangYinping LiuChunyu Huang, Yujun Pei, Xia WangHui Zhi, Wilfred Hing-Sang Wong, Haiming Wei, Irene Oi-Lin Ng, Pamela Pui-Wah Lee, Godfrey Chi-Fung ChanYu-Lung LauWenwei Tu. (2020) Exosomes derived from Vδ2-T cells control Epstein-Barr virus–associated tumors and induce T cell antitumor immunity. Science Translational Medicine 12:563.
Crossref
Simona Villata, Marta Canta & Valentina Cauda. (2020) EVs and Bioengineering: From Cellular Products to Engineered Nanomachines. International Journal of Molecular Sciences 21:17, pages 6048.
Crossref
Ying Lu, Ning Lan, Yigan Zhang, Xin Nie, Shuangshuang Pu & Wenzhen Yuan. (2020) Role of extracellular vesicles in the progression, diagnosis and treatment of thyroid cancer (Review). International Journal of Oncology.
Crossref
Lorenzo Taiarol, Beatrice Formicola, Roberta Dal Magro, Silvia Sesana & Francesca Re. (2020) An update of nanoparticle-based approaches for glioblastoma multiforme immunotherapy. Nanomedicine 15:19, pages 1861-1871.
Crossref
Mei Lu & Yuanyu Huang. (2020) Bioinspired exosome-like therapeutics and delivery nanoplatforms. Biomaterials 242, pages 119925.
Crossref
Amirmohammad Nasiri Kenari, Lesley Cheng & Andrew F. Hill. (2020) Methods for loading therapeutics into extracellular vesicles and generating extracellular vesicles mimetic-nanovesicles. Methods 177, pages 103-113.
Crossref
Anna Di Pace, Nicola Tumino, Francesca Besi, Claudia Alicata, Libenzio Conti, Enrico Munari, Enrico Maggi, Paola Vacca & Lorenzo Moretta. (2020) Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor in Exosome-Mediated Cytotoxicity against Tumor. Cancers 12:3, pages 661.
Crossref
Cao Dai Phung, Tuan Hiep Tran & Jong Oh Kim. (2020) Engineered nanoparticles to enhance natural killer cell activity towards onco-immunotherapy: a review. Archives of Pharmacal Research 43:1, pages 32-45.
Crossref
Prakash Gangadaran & Byeong-Cheol Ahn. 2020. Bioluminescent Imaging. Bioluminescent Imaging 203 210 .
Yue-Feng Zhang, Jin-Bo Shi & Chao Li. (2019) Small extracellular vesicle loading systems in cancer therapy: Current status and the way forward. Cytotherapy 21:11, pages 1122-1136.
Crossref
Irene Golán, Laura Rodríguez de la Fuente & Jose Costoya. (2018) NK Cell-Based Glioblastoma Immunotherapy. Cancers 10:12, pages 522.
Crossref
Enrico Spugnini, Mariantonia Logozzi, Rossella Di Raimo, Davide Mizzoni & Stefano Fais. (2018) A Role of Tumor-Released Exosomes in Paracrine Dissemination and Metastasis. International Journal of Molecular Sciences 19:12, pages 3968.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.