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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 46, 2018 - Issue sup3
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Research Article

Transdermal delivery system of nanostructured lipid carriers loaded with Celastrol and Indomethacin: optimization, characterization and efficacy evaluation for rheumatoid arthritis

Qian KangDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
,
Jia LiuDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
,
Ying ZhaoDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
,
Xin LiuDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
,
Xin-Yan LiuDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
,
Yong-Jie WangDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
,
Nuo-Lan MoDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China
&
Qing WuDepartment of TCM Pharmaceutics, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, ChinaCorrespondence[email protected]
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Pages 585-597 | Received 20 Jun 2018, Accepted 17 Jul 2018, Published online: 11 Oct 2018

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Uzma M, Dhanwini R. Prasad, Sunayana N, Vinay B. Raghavendra & Shilpashree H.P.. (2022) Studies of in vitro antioxidant and anti-inflammatory activities of gold nanoparticles biosynthesised from a medicinal plant, Commiphora wightii. Materials Technology 37:9, pages 915-925.
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Fen Qiu, Long Xi, Shengshuang Chen, Yonghua Zhao, Zhenping Wang & Ying Zheng. (2021) Celastrol Niosome Hydrogel Has Anti-Inflammatory Effect on Skin Keratinocytes and Circulation without Systemic Drug Exposure in Psoriasis Mice. International Journal of Nanomedicine 16, pages 6171-6182.
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Apoorva Phadke & Purnima Amin. (2021) A Recent Update on Drug Delivery Systems for Pain Management. Journal of Pain & Palliative Care Pharmacotherapy 35:3, pages 175-214.
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Jian Huang, Zhengji Wang, Zihe Chen, Chunxin Huang, Ying Wang, Xing Li, Weiyang Lv, Guiqiang Qi & Huilin Liu. (2023) Ultrasound-mediated multifunctional magnetic microbubbles for drug delivery of celastrol in VX2 liver transplant tumors. Drug Delivery and Translational Research.
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Thivya Balendran, Keith Lim, John A. Hamilton & Adrian A. Achuthan. (2023) Targeting transcription factors for therapeutic benefit in rheumatoid arthritis. Frontiers in Immunology 14.
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Rohitas Deshmukh. (2023) Rheumatoid arthritis: Pathophysiology, current therapeutic strategies and recent advances in targeted drug delivery system. Materials Today Communications 35, pages 105877.
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Lingarkar Silpavathi, Mukesh Kumar Das & Debajyoti Das. (2021) Anti-arthritic potentials of aqueous and methanolic leaf extracts of Ardisia solanacea on complete Freund’s adjuvant induced rheumatoid arthritis in rats. Advances in Traditional Medicine 23:1, pages 111-119.
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Hongtao Shang, Ayesha Younas & Nan Zhang. (2022) Recent advances on transdermal delivery systems for the treatment of arthritic injuries: From classical treatment to nanomedicines. WIREs Nanomedicine and Nanobiotechnology 14:3.
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Daohe Wei, Han Yang, Yue Zhang, Xinhui Zhang, Jian Wang, Xiaoli Wu & Jin Chang. (2022) Nano-traditional Chinese medicine: a promising strategy and its recent advances. Journal of Materials Chemistry B 10:16, pages 2973-2994.
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Despoina Despotopoulou, Nefeli Lagopati, Stergios Pispas, Maria Gazouli, Costas Demetzos & Natassa Pippa. (2022) The technology of transdermal delivery nanosystems: from design and development to preclinical studies. International Journal of Pharmaceutics 611, pages 121290.
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Shilpa Raval, Parva Jani, Pravin Patil, Parth Thakkar & Krutika Sawant. (2021) Enhancement of bioavailability through transdermal drug delivery of paliperidone palmitate-loaded nanostructured lipid carriers. Therapeutic Delivery 12:8, pages 583-596.
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Pushkaraj Rajendra Wagh, Preshita Desai, Sunil Prabhu & Jeffrey Wang. (2021) Nanotechnology-Based Celastrol Formulations and Their Therapeutic Applications. Frontiers in Pharmacology 12.
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Ruijiang Liu, Zhixiang Lv, Xiao Liu, Wei Huang, Shuai Pan, Ruitong Yin, Lulu Yu, You Li, Yanling Zhang, Shaoshuai Zhang, Rongzhu Lu, Yongjin Li & Shasha Li. (2021) Improved delivery system for celastrol-loaded magnetic Fe3O4/α-Fe2O3 heterogeneous nanorods: HIF-1α-related apoptotic effects on SMMC-7721 cell. Materials Science and Engineering: C 125, pages 112103.
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Long Chen, Yuanzheng Wang, Li Sun, Jerry Yan & Hai‐Quan Mao. (2021) Nanomedicine Strategies for Anti‐Inflammatory Treatment of Noninfectious Arthritis. Advanced Healthcare Materials 10:11.
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Yue Huo, Ya Xi Han, Priyanka Singh, Jong Pyo Kang, Jian Yu Pu, Chun Hong Piao & Deok Chun Yang. (2021) Antimicrobial, antioxidant, and anticancer potentials of AgCl nanoparticles biosynthesized by Flavobacterium panacis. Applied Physics A 127:4.
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Maimoona Qindeel, Muhammad Hameed Ullah, Fakhar-ud-Din, Naveed Ahmed & Asim.ur. Rehman. (2020) Recent trends, challenges and future outlook of transdermal drug delivery systems for rheumatoid arthritis therapy. Journal of Controlled Release 327, pages 595-615.
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Rui Li, Yanping Li, Jinhang Zhang, Qinhui Liu, Tong Wu, Jian Zhou, Hui Huang, Qin Tang, Cuiyuan Huang, Ya Huang, Zijing Zhang, Guorong Zhang, Yingnan Zhao, Liang Ma, Yanhuan Feng, Li Mo, Min Han & Jinhan He. (2020) Targeted delivery of celastrol to renal interstitial myofibroblasts using fibronectin-binding liposomes attenuates renal fibrosis and reduces systemic toxicity. Journal of Controlled Release 320, pages 32-44.
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Mohamed Haider, Shifaa M. Abdin, Leena Kamal & Gorka Orive. (2020) Nanostructured Lipid Carriers for Delivery of Chemotherapeutics: A Review. Pharmaceutics 12:3, pages 288.
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Xinyan Liu, Lingyan Xu, Xin Liu, Yongjie Wang, Ying Zhao, Qian Kang, Jia Liu, Hai Lan, Ling Yu & Qing Wu. (2020) Combination of essential oil from Zanthoxylum bungeanum Maxim. and a microemulsion system: Permeation enhancement effect on drugs with different lipophilicity and its mechanism. Journal of Drug Delivery Science and Technology 55, pages 101309.
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Kumar Janakiraman, Venkateshwaran Krishnaswami, Vaidevi Sethuraman, Vijaya Rajendran & Ruckmani Kandasamy. (2019) Development of methotrexate-loaded cubosomes with improved skin permeation for the topical treatment of rheumatoid arthritis. Applied Nanoscience 9:8, pages 1781-1796.
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