2,609
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Oral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation

, , ORCID Icon, ORCID Icon & ORCID Icon
Pages 2123-2133 | Received 05 Mar 2019, Accepted 30 Apr 2019, Published online: 03 Jun 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Srinivas Reddy Jitta, Navya Ajitkumar Bhaskaran, Shirleen Miriam Marques & Lalit Kumar. (2022) Recent advances in nanoformulation development of Ritonavir, a key protease inhibitor used in the treatment of HIV-AIDS. Expert Opinion on Drug Delivery 19:9, pages 1133-1148.
Read now
Parnian Mohammadi, Reza Mahjub, Mojdeh Mohammadi, Katayoun Derakhshandeh, Ali Ghaleiha & Mohammad Mehdi Mahboobian. (2021) Pharmacokinetics and brain distribution studies of perphenazine-loaded solid lipid nanoparticles. Drug Development and Industrial Pharmacy 47:1, pages 146-152.
Read now

Articles from other publishers (19)

Prasanta Kumar Mohapatra, Rajnish Srivastava, Krishna Kumar Varshney, Sunit Kumar Sahoo & Asha Kesari. (2023) A Computational Approach for Exploring Indinavir as a Potent Protease Inhibitor and Development of Its Microsphere for Anticancer Activity. Journal of Pharmaceutical Innovation.
Crossref
Cheng Ji. (2023) Molecular Factors and Pathways of Hepatotoxicity Associated with HIV/SARS-CoV-2 Protease Inhibitors. International Journal of Molecular Sciences 24:9, pages 7938.
Crossref
Sankha Bhattacharya, Vipan Kumar Parihar, Neeraj Singh, Ketan Hatware, Amit Page, Mayank Sharma, Mahendra Kumar Prajapati, Abhishek Kanugo, Datta Pawde, Saurabh Maru, Girdhari Lal Gupta & Sunil Kanvinde. (2023) Targeted delivery of panitumumab-scaffold bosutinib-encapsulated polycaprolactone nanoparticles for EGFR-overexpressed colorectal cancer. Nanomedicine 18:9, pages 713-741.
Crossref
Khaled Y. Mahmoud, Nahla A. Elhesaisy, Abdelrahman R. Rashed, Ebram S. Mikhael, Mahmoud I. Fadl, Mahmoud S. Elsadek, Merna A. Mohamed, Merna A. Mostafa, Mohamed A. Hassan, Omar M. Halema, Youssef H. Elnemer & Shady A. Swidan. (2023) Exploring the potential of intranasally administered naturally occurring quercetin loaded into polymeric nanocapsules as a novel platform for the treatment of anxiety. Scientific Reports 13:1.
Crossref
Muhammad Aanish Ali, Nagina Rehman, Tae Joo Park & Muhammad Abdul Basit. (2023) Antiviral role of nanomaterials: a material scientist's perspective. RSC Advances 13:1, pages 47-79.
Crossref
Kasey S. Leung, Sajjad Shirazi, Lyndon F. Cooper & Sriram Ravindran. (2022) Biomaterials and Extracellular Vesicle Delivery: Current Status, Applications and Challenges. Cells 11:18, pages 2851.
Crossref
Deepak A. Subramanian, Robert Langer & Giovanni Traverso. (2022) Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems. Journal of Nanobiotechnology 20:1.
Crossref
Lei Yin, Yiling Pang, Lin Shan & Jingkai Gu. (2022) The In Vivo Pharmacokinetics of Block Copolymers Containing Polyethylene Glycol Used in Nanocarrier Drug Delivery Systems. Drug Metabolism and Disposition 50:6, pages 827-836.
Crossref
Divya Soundararajan, Lakshmi Narashimhan Ramana, Prakash Shankaran & Uma Maheswari Krishnan. (2022) Nanoparticle-based strategies to target HIV-infected cells. Colloids and Surfaces B: Biointerfaces 213, pages 112405.
Crossref
Myla Lôbo de Souza, Victor de Albuquerque Wanderley Sales, Larissa Pereira Alves, Widson Michael dos Santos, Leslie Raphael de Moura Ferraz, Gustavo Siqueira de Andrade Lima, Larissa Morgana dos Santos Mendes, Larissa Araújo Rolim & Pedro José Rolim Neto. (2022) A Systematic Review of Functionalized Polymeric Nanoparticles to Improve Intestinal Permeability of Drugs and Biological Products. Current Pharmaceutical Design 28:5, pages 410-426.
Crossref
Farshid Hajibabaei, Samira Sharifinia, Neda Hosseinpour Moghadam, Sadegh Salehzadeh, Katayoun Derakhshandeh & Sadegh Khazalpour. (2022) In vitro anticancer activities, multi-spectroscopic and in silico DNA binding studies of propranolol drug and its new Zn(II) complex. Results in Chemistry 4, pages 100575.
Crossref
Josef Jampílek & Katarina Kráľová. 2022. Nanotechnological Applications in Virology. Nanotechnological Applications in Virology 129 171 .
Archita Jha & Yashwant Pathak. 2022. Nanotheranostics for Treatment and Diagnosis of Infectious Diseases. Nanotheranostics for Treatment and Diagnosis of Infectious Diseases 127 149 .
Geetika Wadhwa, Kowthavarapu Venkata Krishna, Sunil Kumar Dubey & Rajeev Taliyan. (2021) Development and validation of RP-HPLC method for quantification of repaglinide in mPEG-PCL polymeric nanoparticles: QbD-driven optimization, force degradation study, and assessment of in vitro release mathematic modeling. Microchemical Journal 168, pages 106491.
Crossref
Jonathan Sampath Franklyne, Ponnusamy Manogaran Gopinath, Amitava Mukherjee & Natarajan Chandrasekaran. (2021) Nanoemulsions: The rising star of antiviral therapeutics and nanodelivery system—current status and prospects. Current Opinion in Colloid & Interface Science 54, pages 101458.
Crossref
Muthupandian Saravanan, Ebrahim Mostafavi, Savariar Vincent, Hadush Negash, Rajapriya Andavar, Venkatesan Perumal, Namas Chandra, Selvaraju Narayanasamy, Kalishwaralal Kalimuthu & Hamed Barabadi. (2021) Nanotechnology-based approaches for emerging and re-emerging viruses: Special emphasis on COVID-19. Microbial Pathogenesis 156, pages 104908.
Crossref
Vidiksha Bhushan, Mark P. Heitz, Gary A. Baker & Siddharth Pandey. (2021) Ionic Liquid-Controlled Shape Transformation of Spherical to Nonspherical Polymersomes via Hierarchical Self-Assembly of a Diblock Copolymer. Langmuir 37:16, pages 5081-5088.
Crossref
Govind Soni, Ketaki Kale, Saritha Shetty, M.K. Gupta & Khushwant S. Yadav. (2020) Quality by design (QbD) approach in processing polymeric nanoparticles loading anticancer drugs by high pressure homogenizer. Heliyon 6:4, pages e03846.
Crossref
Niza, Nieto-Jiménez, Noblejas-López, Bravo, Castro-Osma, Cruz-Martínez, Buchaca, Posadas, Canales-Vázquez, Lara-Sanchez, Hermida-Merino, Solano, Ocaña & Alonso-Moreno. (2019) Poly(Cyclohexene Phthalate) Nanoparticles for Controlled Dasatinib Delivery in Breast Cancer Therapy. Nanomaterials 9:9, pages 1208.
Crossref