Artificial Cells, Nanomedicine, and Biotechnology, Volume 47, Issue 1 (2019)

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Artificial Cells, Nanomedicine, and Biotechnology, Volume 47, Issue 1 (2019)

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Research Article

Article
GINS complex subunit 2 (GINS2) plays a protective role in alcohol-induced brain injury
Chunhua Liu, Renfu Wang & Yu Zhang
Pages: 1-9
Published online: 04 Dec 2018
AbstractforGINS complex subunit 2 (GINS2) plays a protective role in alcohol-induced brain injury | Full Text | References | PDF (1.2 MB) | EPUB
  • 1925 Views
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Open Access
Article
Encapsulation of bone marrow-MSCs in PRP-derived fibrin microbeads and preliminary evaluation in a volumetric muscle loss injury rat model: modular muscle tissue engineering
Özge Lalegül-Ülker, Şükran Şeker, Ayşe Eser Elçin & Yaşar Murat Elçin
Pages: 10-21
Published online: 04 Dec 2018
AbstractforEncapsulation of bone marrow-MSCs in PRP-derived fibrin microbeads and preliminary evaluation in a volumetric muscle loss injury rat model: modular muscle tissue engineering | Full Text | References | PDF (1.8 MB) | EPUB
  • 3338 Views
  • 20 CrossRef citations
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Open Access
Article
Therapeutic hypothermia effectively reduces elevated extracellular ascorbate concentrations caused by acute spinal cord injury
Yawen Zhang, Yang Lv, Wenliang Ji, Rubing Zhou, Shan Gao & Fang Zhou
Pages: 22-29
Published online: 11 Dec 2018
AbstractforTherapeutic hypothermia effectively reduces elevated extracellular ascorbate concentrations caused by acute spinal cord injury | Full Text | References | PDF (1,014 KB) | EPUB
  • 2163 Views
  • 3 CrossRef citations
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Open Access
Article
Development of Lactobacillus kimchicus DCY51T-mediated gold nanoparticles for delivery of ginsenoside compound K: in vitro photothermal effects and apoptosis detection in cancer cells
Yeon-Ju Kim, Haribalan Perumalsamy, Josua Markus, Sri Renukadevi Balusamy, Chao Wang, Seong Ho Kang, Seungah Lee, Sang Yong Park, Sung Kim, Verónica Castro-Aceituno, Seung Hyun Kim & Deok Chun Yang
Pages: 30-44
Published online: 19 Jan 2019
AbstractforDevelopment of Lactobacillus kimchicus DCY51T-mediated gold nanoparticles for delivery of ginsenoside compound K: in vitro photothermal effects and apoptosis detection in cancer cells | Full Text | References | PDF (2.3 MB) | EPUB
  • 3998 Views
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Open Access
Article
Improved uptake and therapeutic intervention of curcumin via designing binary lipid nanoparticulate formulation for oral delivery in inflammatory bowel disorder
Manu Sharma, Shipra Sharma & Jyoti Wadhwa
Pages: 45-55
Published online: 19 Jan 2019
AbstractforImproved uptake and therapeutic intervention of curcumin via designing binary lipid nanoparticulate formulation for oral delivery in inflammatory bowel disorder | Full Text | References | PDF (1.1 MB) | EPUB
  • 3533 Views
  • 41 CrossRef citations
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Open Access
Article
Green synthesized selenium nanoparticles using Spermacoce hispida as carrier of s-allyl glutathione: to accomplish hepatoprotective and nephroprotective activity against acetaminophen toxicity
Vennila Krishnan, Chitra Loganathan & Palvannan Thayumanavan
Pages: 56-63
Published online: 22 Jan 2019
AbstractforGreen synthesized selenium nanoparticles using Spermacoce hispida as carrier of s-allyl glutathione: to accomplish hepatoprotective and nephroprotective activity against acetaminophen toxicity | Full Text | References | PDF (1.3 MB) | EPUB
  • 2704 Views
  • 14 CrossRef citations
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Open Access
Article
Design and synthesis of mucoadhesive nanogel containing farnesol: investigation of the effect on HWP1, SAP6 and Rim101 genes expression of Candida albicans in vitro
Fatemeh Nikoomanesh, Shahla Roudbarmohammadi, Mehdi Khoobi, Farnoosh Haghighi & Maryam Roudbary
Pages: 64-72
Published online: 19 Jan 2019
AbstractforDesign and synthesis of mucoadhesive nanogel containing farnesol: investigation of the effect on HWP1, SAP6 and Rim101 genes expression of Candida albicans in vitro | Full Text | References | PDF (970.2 KB) | EPUB
  • 2703 Views
  • 19 CrossRef citations
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Open Access
Article
Semisynthetic supra plasma expanders: a new class of therapeutics to improve microcircualtion in sickle cell anaemia
Fantao Meng, Dhananjaya Kaul, Sangeetha Thangaswamy, Savita Bhutoria, Gary Gerfen, Craig Branch, Marcos Intaglietta & Seetharama A. Acharya
Pages: 73-82
Published online: 19 Jan 2019
AbstractforSemisynthetic supra plasma expanders: a new class of therapeutics to improve microcircualtion in sickle cell anaemia | Full Text | References | PDF (1.2 MB) | EPUB
  • 2109 Views
  • 4 CrossRef citations
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Open Access
Article
Activation of MET promotes resistance to sorafenib in hepatocellular carcinoma cells via the AKT/ERK1/2-EGR1 pathway
Qing-Feng Xiang, Mei-Xiao Zhan, Yong Li, Hui Liang, Cong Hu, Yao-Ming Huang, Jing Xiao, Xu He, Yong-Jie Xin, Min-Shan Chen & Li-Gong Lu
Pages: 83-89
Published online: 19 Jan 2019
AbstractforActivation of MET promotes resistance to sorafenib in hepatocellular carcinoma cells via the AKT/ERK1/2-EGR1 pathway | Full Text | References | PDF (1.4 MB) | EPUB
  • 3786 Views
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Open Access
Article
Synthesis and characterization of PEG-functionalized graphene oxide as an effective pH-sensitive drug carrier
Mohamad Kazempour, Hassan Namazi, Abolfazl Akbarzadeh & Roya Kabiri
Pages: 90-94
Published online: 19 Jan 2019
AbstractforSynthesis and characterization of PEG-functionalized graphene oxide as an effective pH-sensitive drug carrier | Full Text | References | PDF (757.5 KB) | EPUB
  • 4511 Views
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Open Access
Article
Microvascular and systemic responses to novel PEGylated carboxyhaemoglobin-based oxygen carrier in a rat model of vaso-occlusive crisis
William H. Nugent, Ronald Jubin, Peter J. Buontempo, Friedericke Kazo & Bjorn K. Song
Pages: 95-103
Published online: 10 Feb 2019
AbstractforMicrovascular and systemic responses to novel PEGylated carboxyhaemoglobin-based oxygen carrier in a rat model of vaso-occlusive crisis | Full Text | References | PDF (1.3 MB) | EPUB
  • 1750 Views
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Open Access
Article
Biotin-functionalized copolymeric PEG-PCL micelles for in vivo tumour-targeted delivery of artemisinin
Hamed Nosrati, Parisa Barzegari, Hossein Danafar & Hamidreza Kheiri Manjili
Pages: 104-114
Published online: 19 Jan 2019
AbstractforBiotin-functionalized copolymeric PEG-PCL micelles for in vivo tumour-targeted delivery of artemisinin | Full Text | References | PDF (1.5 MB) | EPUB
  • 4189 Views
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Open Access

Retracted Article

Article
RETRACTED ARTICLE: Fluorescent labelling in living dental pulp stem cells by graphene oxide quantum dots
Xincong Li, Haowei Guo, Shuangshuang Ren, Ruirui Fan, Yijun Yu, He Zhang, Chao Liu & Leiying Miao
Pages: 115-122
Published online: 19 Jan 2019
AbstractforRETRACTED ARTICLE: Fluorescent labelling in living dental pulp stem cells by graphene oxide quantum dots | PDF (2.6 MB)
  • 2247 Views
  • 2 CrossRef citations
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Open Access

Research Article

Article
The study of establishment of an in vivo tumor model by three-dimensional cells culture systems methods and evaluation of antitumor effect of biotin-conjugated pullulan acetate nanoparticles
Hongli Chen, Xiangjuan Wei, Hongyang Chen, Hongliang Wei, Yongxue Wang, Wenbin Nan, Qiqing Zhang & Xuejun Wen
Pages: 123-131
Published online: 19 Jan 2019
AbstractforThe study of establishment of an in vivo tumor model by three-dimensional cells culture systems methods and evaluation of antitumor effect of biotin-conjugated pullulan acetate nanoparticles | Full Text | References | PDF (1.2 MB) | EPUB
Schematic illustration for the preparation of Bio-PA/EPI NPs using dialysis method and establishment of tumor model in vivo and in vitro.
  • 2345 Views
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Open Access
Article
Cytotoxicity, dose-enhancement and radiosensitization of glioblastoma cells with rare earth nanoparticles
Victor M. Lu, Felicity Crawshay-Williams, Benjamin White, Amy Elliot, Mark A. Hill & Helen E. Townley
Pages: 132-143
Published online: 19 Jan 2019
AbstractforCytotoxicity, dose-enhancement and radiosensitization of glioblastoma cells with rare earth nanoparticles | Full Text | References | PDF (1.3 MB) | EPUB
  • 3301 Views
  • 22 CrossRef citations
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Open Access
Article
Enhanced intestinal absorption of asenapine maleate by fabricating solid lipid nanoparticles using TPGS: elucidation of transport mechanism, permeability across Caco-2 cell line and in vivo pharmacokinetic studies
Mitali Patel, Veenu Mundada & Krutika Sawant
Pages: 144-153
Published online: 23 Jan 2019
AbstractforEnhanced intestinal absorption of asenapine maleate by fabricating solid lipid nanoparticles using TPGS: elucidation of transport mechanism, permeability across Caco-2 cell line and in vivo pharmacokinetic studies | Full Text | References | PDF (1.3 MB) | EPUB
  • 3513 Views
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Open Access
Article
Folate-conjugated human serum albumin-encapsulated resveratrol nanoparticles: preparation, characterization, bioavailability and targeting of liver tumors
Bolin Lian, Mingfang Wu, Ziqi Feng, Yiping Deng, Chen Zhong & Xiuhua Zhao
Pages: 154-165
Published online: 27 Jan 2019
AbstractforFolate-conjugated human serum albumin-encapsulated resveratrol nanoparticles: preparation, characterization, bioavailability and targeting of liver tumors | Full Text | References | PDF (1.6 MB) | EPUB
  • 4143 Views
  • 37 CrossRef citations
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Open Access
Article
Fabrication of silver nanoparticles using Arnebia hispidissima (Lehm.) A. DC. root extract and unravelling their potential biomedical applications
Shruti Nindawat & Veena Agrawal
Pages: 166-180
Published online: 04 Feb 2019
AbstractforFabrication of silver nanoparticles using Arnebia hispidissima (Lehm.) A. DC. root extract and unravelling their potential biomedical applications | Full Text | References | PDF (2.3 MB) | EPUB
  • 3059 Views
  • 41 CrossRef citations
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Open Access
Article
Liposomal doxorubicin loaded PLGA-PEG-PLGA based thermogel for sustained local drug delivery for the treatment of breast cancer
Dinglingge Cao, Xingxian Zhang, MD. Akabar, Yuan Luo, Hao Wu, Xue Ke & Tianyuan Ci
Pages: 181-191
Published online: 27 Jan 2019
AbstractforLiposomal doxorubicin loaded PLGA-PEG-PLGA based thermogel for sustained local drug delivery for the treatment of breast cancer | Full Text | References | PDF (1.6 MB) | EPUB
  • 7793 Views
  • 70 CrossRef citations
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Open Access
Article
Fabrication and evaluation a transferrin receptor targeting nano-drug carrier for cerebral infarction treatment
Junyi Shen, Zhiming Zhao, Wei Shang, Chunli Liu, Beibei Zhang, Zihan Xu & Hui Cai
Pages: 192-200
Published online: 19 Jan 2019
AbstractforFabrication and evaluation a transferrin receptor targeting nano-drug carrier for cerebral infarction treatment | Full Text | References | PDF (1.2 MB) | EPUB
  • 3745 Views
  • 19 CrossRef citations
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Open Access
Article
A systematic study and effect of PLA/Al2O3 nanoscaffolds as dental resins: mechanochemical properties
Mehdi Ranjbar, Gholamreza Dehghan Noudeh, Maryam-Alsadat Hashemipour & Iman Mohamadzadeh
Pages: 201-209
Published online: 19 Jan 2019
AbstractforA systematic study and effect of PLA/Al2O3 nanoscaffolds as dental resins: mechanochemical properties | Full Text | References | PDF (1.3 MB) | EPUB
  • 2776 Views
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Open Access

Original Articles

Article
Riboflavin immobilized Fe3O4 magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents
Ching-Yi Wu & Yu-Chie Chen
Pages: 210-220
Published online: 19 Jan 2019
AbstractforRiboflavin immobilized Fe3O4 magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents | Full Text | References | PDF (1.8 MB) | EPUB
  • 3069 Views
  • 20 CrossRef citations
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Open Access

Research Article

Article
Quartz crystal microbalance based histidine sensor
Merve Sönmezler, Erdoğan Özgür, Handan Yavuz & Adil Denizli
Pages: 221-227
Published online: 27 Jan 2019
AbstractforQuartz crystal microbalance based histidine sensor | Full Text | References | PDF (937.5 KB) | EPUB
  • 2462 Views
  • 14 CrossRef citations
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Open Access
Article
Ciprofloxacin HCl and quercetin functionalized electrospun nanofiber membrane: fabrication and its evaluation in full thickness wound healing
Gufran Ajmal, Gunjan Vasant Bonde, Sathish Thokala, Pooja Mittal, Gayasuddin Khan, Juhi Singh, Vivek Kumar Pandey & Brahmeshwar Mishra
Pages: 228-240
Published online: 27 Jan 2019
AbstractforCiprofloxacin HCl and quercetin functionalized electrospun nanofiber membrane: fabrication and its evaluation in full thickness wound healing | Full Text | References | PDF (2.5 MB) | EPUB
  • 4373 Views
  • 45 CrossRef citations
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Open Access
Article
In-vitro haemocompatibility of dextran-protein submicron particles
Chiraphat Kloypan, Nittiya Suwannasom, Saranya Chaiwaree, Ausanai Prapan, Kathrin Smuda, Nuttakorn Baisaeng, Axel Pruß, Radostina Georgieva & Hans Bäumler
Pages: 241-249
Published online: 19 Jan 2019
AbstractforIn-vitro haemocompatibility of dextran-protein submicron particles | Full Text | References | PDF (1.1 MB) | EPUB
  • 2528 Views
  • 7 CrossRef citations
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Open Access

Retracted Article

Article
RETRACTED ARTICLE: Flot2 targeted by miR-449 acts as a prognostic biomarker in glioma
Shaosong Huang, Shihao Zheng, Shengyue Huang, Hui Cheng, Ying Lin, Yuxing Wen & Wei Lin
Pages: 250-255
Published online: 19 Jan 2019
AbstractforRETRACTED ARTICLE: Flot2 targeted by miR-449 acts as a prognostic biomarker in glioma | PDF (1.7 MB)
  • 1849 Views
  • 11 CrossRef citations
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Open Access

Research Article

Article
Polymerization-sensitive switch-on monomer for terminal transferase activity assay
Bhagwan S. Batule, Chang Yeol Lee, Ki Soo Park & Hyun Gyu Park
Pages: 256-259
Published online: 27 Jan 2019
AbstractforPolymerization-sensitive switch-on monomer for terminal transferase activity assay | Full Text | References | PDF (953 KB) | EPUB
  • 2012 Views
  • 4 CrossRef citations
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Open Access
Article
Effect of exposure of osteoblast-like cells to low-dose silver nanoparticles: uptake, retention and osteogenic activity
Hongjun Xie, Pei Wang & Jie Wu
Pages: 260-267
Published online: 19 Jan 2019
AbstractforEffect of exposure of osteoblast-like cells to low-dose silver nanoparticles: uptake, retention and osteogenic activity | Full Text | References | PDF (1.2 MB) | EPUB
  • 2593 Views
  • 24 CrossRef citations
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Open Access

Review

Review
Efficacy and safety of nanoparticle albumin-bound paclitaxel in non-small cell lung cancer: a systematic review and meta-analysis
Hong Tan, Jing Hu & Shan Liu
Pages: 268-277
Published online: 02 Jan 2019
AbstractforEfficacy and safety of nanoparticle albumin-bound paclitaxel in non-small cell lung cancer: a systematic review and meta-analysis | Full Text | References | PDF (1.3 MB) | EPUB
  • 5343 Views
  • 19 CrossRef citations
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Open Access

Original Research Article

Article
MiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF
Hu Zhao, Wei Zhang, Xiaofeng Lai, Hehuan Zhu, Shenhang Zhang, Weizhen Wu, Shuiliang Wang, Minying Tang, Zhen Deng & Jianming Tan
Pages: 278-289
Published online: 23 Jan 2019
AbstractforMiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF | Full Text | References | PDF (1.8 MB) | EPUB
  • 3014 Views
  • 24 CrossRef citations
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Open Access

Research Article

Article
Effect of titanium implants with coatings of different pore sizes on adhesion and osteogenic differentiation of BMSCs
Wuchao Zhou, Ou Huang, Yanzi Gan, Qishun Li, Tian Zhou & Weihong Xi
Pages: 290-299
Published online: 27 Jan 2019
AbstractforEffect of titanium implants with coatings of different pore sizes on adhesion and osteogenic differentiation of BMSCs | Full Text | References | PDF (1.6 MB) | EPUB
  • 2743 Views
  • 21 CrossRef citations
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Open Access
Article
In vitro osteogenic differentiation of stem cells with different sources on composite scaffold containing natural bioceramic and polycaprolactone
Fatemeh Sadat Hosseini, Fatemeh Soleimanifar, Abdolreza Ardeshirylajimi, Saeid Vakilian, Majid Mossahebi-Mohammadi, Seyed Ehsan Enderami, Arash Khojasteh & Shohreh Zare Karizi
Pages: 300-307
Published online: 27 Jan 2019
AbstractforIn vitro osteogenic differentiation of stem cells with different sources on composite scaffold containing natural bioceramic and polycaprolactone | Full Text | References | PDF (1.2 MB) | EPUB
  • 2907 Views
  • 27 CrossRef citations
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Open Access
Article
Hsa_circ_0067997 promotes the progression of gastric cancer by inhibition of miR-515-5p and activation of X chromosome-linked inhibitor of apoptosis (XIAP)
Haibo Zhang, Xiumin Wang, Hongchun Huang, Yongfeng Wang, Fangfang Zhang & Shaofang Wang
Pages: 308-318
Published online: 27 Jan 2019
AbstractforHsa_circ_0067997 promotes the progression of gastric cancer by inhibition of miR-515-5p and activation of X chromosome-linked inhibitor of apoptosis (XIAP) | Full Text | References | PDF (1.6 MB) | EPUB
  • 2426 Views
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Open Access
Article
Comparative evaluation of hesperetin loaded nanoparticles for anticancer activity against C6 glioma cancer cells
Melike Ersoz, Aysegul Erdemir, Dilek Duranoglu, Deniz Uzunoglu, Tulin Arasoglu, Serap Derman & Banu Mansuroglu
Pages: 319-329
Published online: 27 Jan 2019
AbstractforComparative evaluation of hesperetin loaded nanoparticles for anticancer activity against C6 glioma cancer cells | Full Text | References | PDF (1.4 MB) | EPUB
  • 5066 Views
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Open Access
Article
Folate-modified and curcumin-loaded dendritic magnetite nanocarriers for the targeted thermo-chemotherapy of cancer cells
Alireza Montazerabadi, Jaber Beik, Rasoul Irajirad, Neda Attaran, Sajed Khaledi, Habib Ghaznavi & Ali Shakeri-Zadeh
Pages: 330-340
Published online: 27 Jan 2019
AbstractforFolate-modified and curcumin-loaded dendritic magnetite nanocarriers for the targeted thermo-chemotherapy of cancer cells | Full Text | References | PDF (1.5 MB) | EPUB
  • 3171 Views
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Open Access
Article
Green synthesis of zinc oxide nanoparticles using different plant extracts and their antibacterial activity against Xanthomonas oryzae pv. oryzae
Solabomi Olaitan Ogunyemi, Yasmine Abdallah, Muchen Zhang, Hatem Fouad, Xianxian Hong, Ezzeldin Ibrahim, Md. Mahidul Islam Masum, Afsana Hossain, Jianchu Mo & Bin Li
Pages: 341-352
Published online: 29 Jan 2019
AbstractforGreen synthesis of zinc oxide nanoparticles using different plant extracts and their antibacterial activity against Xanthomonas oryzae pv. oryzae | Full Text | References | PDF (1.8 MB) | EPUB
  • 23029 Views
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Open Access
Article
Biocompatible disulphide cross-linked sodium alginate derivative nanoparticles for oral colon-targeted drug delivery
Asila Dinie Ayub, Hock Ing Chiu, Siti Nur Aishah Mat Yusuf, Erazuliana Abd Kadir, Siti Hawa Ngalim & Vuanghao Lim
Pages: 353-369
Published online: 29 Jan 2019
AbstractforBiocompatible disulphide cross-linked sodium alginate derivative nanoparticles for oral colon-targeted drug delivery | Full Text | References | PDF (3.3 MB) | EPUB
  • 4407 Views
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Open Access
Article
Enhancement of the effect of BCG vaccine against tuberculosis using DDA/TDB liposomes containing a fusion protein of HspX, PPE44, and EsxV
Davood Mansury, Kiarash Ghazvini, Saeid Amel Jamehdar, Ali Badiee, Mohsen Tafaghodi, Amin Reza Nikpoor, Yousef Amini & Mahmoud Reza Jaafari
Pages: 370-377
Published online: 29 Jan 2019
AbstractforEnhancement of the effect of BCG vaccine against tuberculosis using DDA/TDB liposomes containing a fusion protein of HspX, PPE44, and EsxV | Full Text | References | PDF (966.5 KB) | EPUB
  • 2597 Views
  • 16 CrossRef citations
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Open Access
Article
Fabrication of hesperidin nanoparticles loaded by poly lactic co-Glycolic acid for improved therapeutic efficiency and cytotoxicity
Saja H. Ali, Ghassan M. Sulaiman, Mohammad M. F. Al-Halbosiy, Majid S. Jabir & Anaheed H. Hameed
Pages: 378-394
Published online: 29 Jan 2019
AbstractforFabrication of hesperidin nanoparticles loaded by poly lactic co-Glycolic acid for improved therapeutic efficiency and cytotoxicity | Full Text | References | PDF (2.7 MB) | EPUB
  • 6056 Views
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Review

Review
Polymers, responsiveness and cancer therapy
Anil M. Pethe & Khushwant S. Yadav
Pages: 395-405
Published online: 27 Jan 2019
AbstractforPolymers, responsiveness and cancer therapy | Full Text | References | PDF (1.1 MB) | EPUB
  • 4840 Views
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Open Access

Research Article

Article
Self-assembled thermal gold nanorod-loaded thermosensitive liposome-encapsulated ganoderic acid for antibacterial and cancer photochemotherapy
Weiwei Zhang, Wenwen Yu, Xiaoyuan Ding, Chenyang Yin, Jing Yan, Endong Yang, Feng Guo, Dongdong Sun & Weiyun Wang
Pages: 406-419
Published online: 06 Feb 2019
AbstractforSelf-assembled thermal gold nanorod-loaded thermosensitive liposome-encapsulated ganoderic acid for antibacterial and cancer photochemotherapy | Full Text | References | PDF (4.8 MB) | EPUB
  • 2811 Views
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Open Access
Article
Capecitabine-loaded nanoniosomes and evaluation of anticancer efficacy
R. Nazari-Vanani, K. Karimian, N. Azarpira & H. Heli
Pages: 420-426
Published online: 23 Jan 2019
AbstractforCapecitabine-loaded nanoniosomes and evaluation of anticancer efficacy | Full Text | References | PDF (999.9 KB) | EPUB
  • 4149 Views
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Article
Nano-Rifabutin entrapment within glucan microparticles enhances protection against intracellular Mycobacterium tuberculosis
Tarun K. Upadhyay, Nida Fatima, Akanksha Sharma, Deepak Sharma & Rolee Sharma
Pages: 427-435
Published online: 23 Jan 2019
AbstractforNano-Rifabutin entrapment within glucan microparticles enhances protection against intracellular Mycobacterium tuberculosis | Full Text | References | PDF (1 MB) | EPUB
  • 2710 Views
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Original Research Article

Article
Layered double hydroxide nanoparticles as an appealing nanoparticle in gene/plasmid and drug delivery system in C2C12 myoblast cells
Parivar Yazdani, Elham Mansouri, Shirin Eyvazi, Vahid Yousefi, Homan Kahroba, Mohammad Saeid Hejazi, Asghar Mesbahi, Vahideh Tarhriz & Mir Mahdi Abolghasemi
Pages: 436-442
Published online: 01 Feb 2019
AbstractforLayered double hydroxide nanoparticles as an appealing nanoparticle in gene/plasmid and drug delivery system in C2C12 myoblast cells | Full Text | References | PDF (1.1 MB) | EPUB
  • 3945 Views
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Research Article

Article
Stimuli-responsive polyvinylpyrrolidone-NIPPAm-lysine graphene oxide nano-hybrid as an anticancer drug delivery on MCF7 cell line
Maryam Ashjaran, Mirzaagha Babazadeh, Abolfazl Akbarzadeh, Soodabeh Davaran & Roya Salehi
Pages: 443-454
Published online: 27 Jan 2019
AbstractforStimuli-responsive polyvinylpyrrolidone-NIPPAm-lysine graphene oxide nano-hybrid as an anticancer drug delivery on MCF7 cell line | Full Text | References | PDF (1.6 MB) | EPUB
  • 2501 Views
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Review

Review
Gold nanoparticles and hepatitis B virus
Babak Negahdari, Mohammad Darvishi & Ali Asghar Saeedi
Pages: 455-461
Published online: 06 Mar 2019
AbstractforGold nanoparticles and hepatitis B virus | Full Text | References | PDF (888.7 KB) | EPUB
  • 4352 Views
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Review
Pain management using nanotechnology approaches
Siavash Beiranvand & Mohamad Masud Sorori
Pages: 462-468
Published online: 27 Jan 2019
AbstractforPain management using nanotechnology approaches | Full Text | References | PDF (707.3 KB) | EPUB
  • 6123 Views
  • 15 CrossRef citations
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Review
Gold nanoparticles and hepatitis B virus
Babak Negahdari, Mohammad Darvishi & Ali Asghar Saeedi
Pages: 469-474
Published online: 27 Jan 2019
AbstractforGold nanoparticles and hepatitis B virus | Full Text | References | PDF (797.2 KB) | EPUB
  • 4071 Views
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Open Access

Retracted Article

Article
RETRACTED ARTICLE: Brain-targeted glycyrrhizic-acid-loaded surface decorated nanoparticles for treatment of cerebral ischaemia and its toxicity assessment
Niyaz Ahmad, Abeer M. Al-Subaie, Rizwan Ahmad, Sonali Sharma, Md Aftab Alam, Mohammad Ashafaq, Rehan Abdur Rub & Farhan Jalees Ahmad
Pages: 475-490
Published online: 10 Feb 2019
AbstractforRETRACTED ARTICLE: Brain-targeted glycyrrhizic-acid-loaded surface decorated nanoparticles for treatment of cerebral ischaemia and its toxicity assessment | PDF (4.3 MB)
  • 2687 Views
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Research Article

Article
Expanded 3D nanofibre sponge scaffolds by gas-foaming technique enhance peripheral nerve regeneration
Feng Rao, Zhipeng Yuan, Ming Li, Fei Yu, Xingxing Fang, Baoguo Jiang, Yongqiang Wen & Peixun Zhang
Pages: 491-500
Published online: 03 Apr 2019
AbstractforExpanded 3D nanofibre sponge scaffolds by gas-foaming technique enhance peripheral nerve regeneration | Full Text | References | PDF (1.8 MB) | EPUB
  • 3549 Views
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Open Access
Article
Polyethyleneimine-polyethylene glycol copolymer targeted by anti-HER2 nanobody for specific delivery of transcriptionally targeted tBid containing construct
Batoul Saqafi & Fatemeh Rahbarizadeh
Pages: 501-511
Published online: 27 Feb 2019
AbstractforPolyethyleneimine-polyethylene glycol copolymer targeted by anti-HER2 nanobody for specific delivery of transcriptionally targeted tBid containing construct | Full Text | References | PDF (1.5 MB) | EPUB
  • 3264 Views
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Open Access
Article
Synthesis and characterization of gold nanoparticles from Abies spectabilis extract and its anticancer activity on bladder cancer T24 cells
Tao Wu, Xi Duan, Chunyan Hu, Changqiang Wu, Xiaobin Chen, Jing Huang, Junbo Liu & Shu Cui
Pages: 512-523
Published online: 27 Feb 2019
AbstractforSynthesis and characterization of gold nanoparticles from Abies spectabilis extract and its anticancer activity on bladder cancer T24 cells | Full Text | References | PDF (1.6 MB) | EPUB
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Review

Review
In vitro and in vivo characterization of pharmaceutical nanocarriers used for drug delivery
Akhlesh K. Jain & Suresh Thareja
Pages: 524-539
Published online: 20 Feb 2019
AbstractforIn vitro and in vivo characterization of pharmaceutical nanocarriers used for drug delivery | Full Text | References | PDF (1.6 MB) | EPUB
  • 23898 Views
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Research Article

Article
Microwave-assisted and one-step synthesis of PEG passivated fluorescent carbon dots from gelatin as an efficient nanocarrier for methotrexate delivery
Nasser Arsalani, Parinaz Nezhad-Mokhtari & Esmaiel Jabbari
Pages: 540-547
Published online: 04 Mar 2019
AbstractforMicrowave-assisted and one-step synthesis of PEG passivated fluorescent carbon dots from gelatin as an efficient nanocarrier for methotrexate delivery | Full Text | References | PDF (1.2 MB) | EPUB
  • 6254 Views
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Article
miR-429 suppresses cell growth and induces apoptosis of human thyroid cancer cell by targeting ZEB1
Guochang Wu, Haitao Zheng, Jie Xu, Yawen Guo, Guibin Zheng, Ci Ma, Shaolong Hao, Xincheng Liu, Huanjie Chen, Shujian Wei, Xicheng Song & Xiaojie Wang
Pages: 548-554
Published online: 08 Mar 2019
AbstractformiR-429 suppresses cell growth and induces apoptosis of human thyroid cancer cell by targeting ZEB1 | Full Text | References | PDF (932.6 KB) | EPUB
  • 2850 Views
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Article
SP1-induced up-regulation of lncRNA LUCAT1 promotes proliferation, migration and invasion of cervical cancer by sponging miR-181a
Liang Zhang, Shi-Kai Liu, Lili Song & Hai-Rong Yao
Pages: 555-563
Published online: 04 Mar 2019
AbstractforSP1-induced up-regulation of lncRNA LUCAT1 promotes proliferation, migration and invasion of cervical cancer by sponging miR-181a | Full Text | References | PDF (1.9 MB) | EPUB
  • 3029 Views
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Article
Chitosan-hyaluronan: promotion of mucociliary differentiation of respiratory epithelial cells and development of olfactory receptor neurons
Tsung-Wei Huang, Sheng-Tien Li & Tai-Horng Young
Pages: 564-570
Published online: 11 Mar 2019
AbstractforChitosan-hyaluronan: promotion of mucociliary differentiation of respiratory epithelial cells and development of olfactory receptor neurons | Full Text | References | PDF (1.2 MB) | EPUB
  • 2044 Views
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Article
Combinatorial therapeutic approach for treatment of oral squamous cell carcinoma
Rituraj Bharadwaj, Bhanu P. Sahu, Jayanta Haloi, Damiki Laloo, Prajjalendra Barooah, Chenole Keppen, Manab Deka & Subhash Medhi
Pages: 571-584
Published online: 04 Mar 2019
AbstractforCombinatorial therapeutic approach for treatment of oral squamous cell carcinoma | Full Text | References | PDF (3.3 MB) | EPUB
  • 3578 Views
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Article
The combined effects of hierarchical scaffolds and mechanical stimuli on ex vivo expansion of haematopoietic stem/progenitor cells
Ji Eun Kim, Eun Jin Lee, Yanru Wu, Yun Gyeong Kang & Jung-Woog Shin
Pages: 585-592
Published online: 04 Mar 2019
AbstractforThe combined effects of hierarchical scaffolds and mechanical stimuli on ex vivo expansion of haematopoietic stem/progenitor cells | Full Text | References | PDF (1.7 MB) | EPUB
  • 1843 Views
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Review

Review
Haemoglobin-based oxygen carriers and myocardial infarction
Timothy N. Estep
Pages: 593-601
Published online: 08 Mar 2019
AbstractforHaemoglobin-based oxygen carriers and myocardial infarction | Full Text | References | PDF (803.1 KB) | EPUB
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Research Article

Article
Notoginsenoside R1 promotes MC3T3-E1 differentiation by up-regulating miR-23a via MAPK and JAK1/STAT3 pathways
Chunsheng Wang, Huanwei Sun & Yiming Zhong
Pages: 602-608
Published online: 04 Mar 2019
AbstractforNotoginsenoside R1 promotes MC3T3-E1 differentiation by up-regulating miR-23a via MAPK and JAK1/STAT3 pathways | Full Text | References | PDF (877.7 KB) | EPUB
  • 2330 Views
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Review

Review
Ursolic acid nanoparticles for oral delivery prepared by emulsion solvent evaporation method: characterization, in vitro evaluation of radical scavenging activity and bioavailability
Lin Qiu, Xiuhua Zhao, Yuangang Zu, Yin Zhang, Yanjie Liu, Weiwei Wu & Yuanyuan Li
Pages: 609-620
Published online: 04 Mar 2019
AbstractforUrsolic acid nanoparticles for oral delivery prepared by emulsion solvent evaporation method: characterization, in vitro evaluation of radical scavenging activity and bioavailability | Full Text | References | PDF (1.9 MB) | EPUB
  • 3226 Views
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Research Article

Article
Fluorescence, turn-on detection of melamine based on its dual functions as fluorescence enhancer of DNA-AgNCs and Hg(II)-scavenger
Sehan Jeong, Woo Young Kwon, Sung Hyun Hwang, Jiye Shin, Yonghwan Kim, Miran Lee & Ki Soo Park
Pages: 621-625
Published online: 15 Mar 2019
AbstractforFluorescence, turn-on detection of melamine based on its dual functions as fluorescence enhancer of DNA-AgNCs and Hg(II)-scavenger | Full Text | References | PDF (782.8 KB) | EPUB
  • 2064 Views
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Article
Shikonin induces apoptosis and prosurvival autophagy in human melanoma A375 cells via ROS-mediated ER stress and p38 pathways
Yongkang Liu, Xing Kang, Geng Niu, Senlin He, Tingting Zhang, Yuwei Bai, Yi Li, Houyan Hao, Chao Chen, Zhexing Shou & Bin Li
Pages: 626-635
Published online: 15 Mar 2019
AbstractforShikonin induces apoptosis and prosurvival autophagy in human melanoma A375 cells via ROS-mediated ER stress and p38 pathways | Full Text | References | PDF (1.4 MB) | EPUB
  • 4291 Views
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Article
A PCR-lateral flow assay system based on gold magnetic nanoparticles for CYP2C19 genotyping and its clinical applications
Yan Xuhong, Zhang Sinong, Liang Jianping, Cai Yu, Zhu Juanli, Zhang Chao, Li Desheng, Hua Kai, Cui Yali & Hui Wenli
Pages: 636-643
Published online: 15 Mar 2019
AbstractforA PCR-lateral flow assay system based on gold magnetic nanoparticles for CYP2C19 genotyping and its clinical applications | Full Text | References | PDF (1.2 MB) | EPUB
  • 3326 Views
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Article
A potential dermal substitute using decellularized dermis extracellular matrix derived bio-ink
Joo-Yun Won, Mi-Hee Lee, Mi-Jeong Kim, Kyung-Hyun Min, Geunseon Ahn, Ji-Seok Han, Songwan Jin, Won-Soo Yun & Jin-Hyung Shim
Pages: 644-649
Published online: 15 Mar 2019
AbstractforA potential dermal substitute using decellularized dermis extracellular matrix derived bio-ink | Full Text | References | PDF (873.9 KB) | EPUB
  • 5682 Views
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Article
Graphene oxide-PLGA hybrid nanofibres for the local delivery of IGF-1 and BDNF in spinal cord repair
Su Pan, Zhiping Qi, Qiuju Li, Yue Ma, Chuan Fu, Shuang Zheng, Weijian Kong, Qinyi Liu & Xiaoyu Yang
Pages: 650-663
Published online: 04 Mar 2019
AbstractforGraphene oxide-PLGA hybrid nanofibres for the local delivery of IGF-1 and BDNF in spinal cord repair | Full Text | References | PDF (3.5 MB) | EPUB
  • 4507 Views
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Article
P435 HER2/neu-derived peptide conjugated to liposomes containing DOPE as an effective prophylactic vaccine formulation for breast cancer
Niloofar Farzad, Nastaran Barati, Amir Abbas Momtazi-Borojeni, Mona Yazdani, Atefeh Arab, Atefeh Razazan, Sheida Shariat, Mercedeh Mansourian, Azam Abbasi, Zahra Saberi, Ali Badiee, Seyed Amir Jalali & Mahmoud Reza Jaafari
Pages: 664-672
Published online: 04 Mar 2019
AbstractforP435 HER2/neu-derived peptide conjugated to liposomes containing DOPE as an effective prophylactic vaccine formulation for breast cancer | Full Text | References | PDF (1.7 MB) | EPUB
  • 3042 Views
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Article
Synergies of accelerating differentiation of bone marrow mesenchymal stem cells induced by low intensity pulsed ultrasound, osteogenic and endothelial inductive agent
Ruixin He, Junlin Chen, Jingwei Jiang, Baoru Liu, Dandan Liang, Weichen Zhou, Wenzhi Chen & Yan Wang
Pages: 673-683
Published online: 05 Mar 2019
AbstractforSynergies of accelerating differentiation of bone marrow mesenchymal stem cells induced by low intensity pulsed ultrasound, osteogenic and endothelial inductive agent | Full Text | References | PDF (3.3 MB) | EPUB
  • 2459 Views
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Article
Plastin 3 down-regulation augments the sensitivity of MDA-MB-231 cells to paclitaxel via the p38 MAPK signalling pathway
Yan Ma, Wenjia Lai, Minzhi Zhao, Chunyan Yue, Fanghao Shi, Ren Li & Zhiyuan Hu
Pages: 684-694
Published online: 04 Mar 2019
AbstractforPlastin 3 down-regulation augments the sensitivity of MDA-MB-231 cells to paclitaxel via the p38 MAPK signalling pathway | Full Text | References | PDF (1.7 MB) | EPUB
  • 2519 Views
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Review

Review
Combined vaccines for prophylaxis of infectious conditions
Pravin Shende & Mansi Waghchaure
Pages: 695-704
Published online: 04 Mar 2019
AbstractforCombined vaccines for prophylaxis of infectious conditions | Full Text | References | PDF (1.3 MB) | EPUB
  • 3919 Views
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Research Article

Article
Ultrasonically controlled albumin-conjugated liposomes for breast cancer therapy
Nahid S. Awad, Vinod Paul, Mohammad H. Al-Sayah & Ghaleb A. Husseini
Pages: 705-714
Published online: 15 Mar 2019
AbstractforUltrasonically controlled albumin-conjugated liposomes for breast cancer therapy | Full Text | References | PDF (2 MB) | EPUB
  • 2986 Views
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Article
Silver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata
Amir Ali, Sher Mohammad, Mubarak Ali Khan, Naveed Iqbal Raja, Mohammad Arif, Atif Kamil & Zia-ur-Rehman Mashwani
Pages: 715-724
Published online: 11 Mar 2019
AbstractforSilver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata | Full Text | References | PDF (1.5 MB) | EPUB
  • 8793 Views
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Article
MiR-483-3p regulates oxaliplatin resistance by targeting FAM171B in human colorectal cancer cells
Hui Liang, Yisong Xu, Qiang Zhang, Yu Yang, Yueyang Mou, Yingchun Gao, Rui Chen, Chao Chen & Penggao Dai
Pages: 725-736
Published online: 12 Mar 2019
AbstractforMiR-483-3p regulates oxaliplatin resistance by targeting FAM171B in human colorectal cancer cells | Full Text | References | PDF (1.4 MB) | EPUB
  • 3024 Views
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Article
Enhanced anti-proliferative and pro-apoptotic effects of metformin encapsulated PLGA-PEG nanoparticles on SKOV3 human ovarian carcinoma cells
Leila Faramarzi, Mehdi Dadashpour, Hadi Sadeghzadeh, Majid Mahdavi & Nosratollah Zarghami
Pages: 737-746
Published online: 20 Mar 2019
AbstractforEnhanced anti-proliferative and pro-apoptotic effects of metformin encapsulated PLGA-PEG nanoparticles on SKOV3 human ovarian carcinoma cells | Full Text | References | PDF (1.3 MB) | EPUB
  • 3859 Views
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Article
Chitosan nanoparticles induced the antitumor effect in hepatocellular carcinoma cells by regulating ROS-mediated mitochondrial damage and endoplasmic reticulum stress
Yibing Jiang, Xiwei Yu, Chang Su, Liang Zhao & Yijie Shi
Pages: 747-756
Published online: 15 Mar 2019
AbstractforChitosan nanoparticles induced the antitumor effect in hepatocellular carcinoma cells by regulating ROS-mediated mitochondrial damage and endoplasmic reticulum stress | Full Text | References | PDF (1.4 MB) | EPUB
  • 2703 Views
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Article
Inonotus obliquus polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance
Yi-Fang Chen, Jin-Juan Zheng, Chao Qu, Yao Xiao, Fang-Fang Li, Quan-Xin Jin, Hong-Hua Li, Fan-Ping Meng, Gui-Hua Jin & Dan Jin
Pages: 757-766
Published online: 11 Mar 2019
AbstractforInonotus obliquus polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance | Full Text | References | PDF (1.5 MB) | EPUB
  • 7401 Views
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Retracted Article

Article
RETRACTED ARTICLE: Long non-coding XIAP-AS1 regulates cell proliferation, invasion and cell cycle in colon cancer
Xiaohong Lu, Yuanjie Yu & Shiyun Tan
Pages: 767-775
Published online: 20 Mar 2019
AbstractforRETRACTED ARTICLE: Long non-coding XIAP-AS1 regulates cell proliferation, invasion and cell cycle in colon cancer | PDF (2.3 MB)
  • 1960 Views
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Research Article

Article
LncRNA SBF2-AS1 promotes the progression of cervical cancer by regulating miR-361-5p/FOXM1 axis
Fangyuan Gao, Jing Feng, Hairong Yao, Yanying Li, Jie Xi & Jun Yang
Pages: 776-782
Published online: 11 Mar 2019
AbstractforLncRNA SBF2-AS1 promotes the progression of cervical cancer by regulating miR-361-5p/FOXM1 axis | Full Text | References | PDF (1.1 MB) | EPUB
  • 2456 Views
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Article
In vitro model to compare the oxygen offloading behaviour of dodecafluoropentane emulsion (DDFPe)
Meghna S. Jayaraman, Kaitlin Graham & Evan C. Unger
Pages: 783-789
Published online: 15 Mar 2019
AbstractforIn vitro model to compare the oxygen offloading behaviour of dodecafluoropentane emulsion (DDFPe) | Full Text | References | PDF (1.1 MB) | EPUB
  • 1851 Views
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Article
Preparation, in vitro release and antibacterial activity evaluation of rifampicin and moxifloxacin-loaded poly(D,L-lactide-co-glycolide) microspheres
ZeWen Qiao, Zhi Yuan, Wenping Zhang, Daihao Wei & Ningmin Hu
Pages: 790-798
Published online: 20 Mar 2019
AbstractforPreparation, in vitro release and antibacterial activity evaluation of rifampicin and moxifloxacin-loaded poly(D,L-lactide-co-glycolide) microspheres | Full Text | References | PDF (1.4 MB) | EPUB
  • 2731 Views
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Article
mPEG-icariin nanoparticles for treating myocardial ischaemia
Yongqiang Zheng, Lingli Lu, Zhengli Yan, Sufang Jiang, Shanyi Yang, Yingzi Zhang, Kangwei Xu, Chunlian He, Xiaojun Tao & Qiufang Zhang
Pages: 799-809
Published online: 06 Mar 2019
AbstractformPEG-icariin nanoparticles for treating myocardial ischaemia | Full Text | References | PDF (2.3 MB) | EPUB
  • 2864 Views
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Article
A novel circular RNA, hsa_circ_0043278, acts as a potential biomarker and promotes non-small cell lung cancer cell proliferation and migration by regulating miR-520f
Jinggang Cui, Wei Li, Guohua Liu, Xiaojun Chen, Xiaolai Gao, Huiling Lu & Dang Lin
Pages: 810-821
Published online: 15 Mar 2019
AbstractforA novel circular RNA, hsa_circ_0043278, acts as a potential biomarker and promotes non-small cell lung cancer cell proliferation and migration by regulating miR-520f | Full Text | References | PDF (1.8 MB) | EPUB
  • 2847 Views
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Article
Effects of graphene oxide and graphene oxide quantum dots on the osteogenic differentiation of stem cells from human exfoliated deciduous teeth
Xin Yang, Qi Zhao, Yijing Chen, Yuanxiang Fu, Shushen Lu, Xinlin Yu, Dongsheng Yu & Wei Zhao
Pages: 822-832
Published online: 15 Mar 2019
AbstractforEffects of graphene oxide and graphene oxide quantum dots on the osteogenic differentiation of stem cells from human exfoliated deciduous teeth | Full Text | References | PDF (1.6 MB) | EPUB
  • 3119 Views
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Retracted Article

Article
RETRACTED ARTICLE: The Notch signal mediates macrophage polarization by regulating miR-125a/miR-99b expression
Qian Li, Xia He, Qiao Yu, Yuan Wu, Mingyu Du, Jing Chen, Fanyu Peng, Wenjun Zhang, Jie Chen, Yan Wang, Hanbo Chen, Hairong Wang, Dan He & Qiang Wang
Pages: 833-843
Published online: 11 Mar 2019
AbstractforRETRACTED ARTICLE: The Notch signal mediates macrophage polarization by regulating miR-125a/miR-99b expression | PDF (3.1 MB)
  • 2106 Views
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Review

Review
Advances in green synthesis of nanoparticles
Aman Gour & Narendra Kumar Jain
Pages: 844-851
Published online: 18 Mar 2019
AbstractforAdvances in green synthesis of nanoparticles | Full Text | References | PDF (878.6 KB) | EPUB
  • 63776 Views
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Research Article

Article
Physicochemical properties and oxygen affinity of glutaraldehyde polymerized crocodile hemoglobin: the new alternative hemoglobin source for hemoglobin-based oxygen carriers
Napaporn Roamcharern, Wisarut Payoungkiattikun, Preeyanan Anwised, Bancha Mahong, Nisachon Jangpromma, Sakda Daduang & Sompong Klaynongsruang
Pages: 852-861
Published online: 15 Mar 2019
AbstractforPhysicochemical properties and oxygen affinity of glutaraldehyde polymerized crocodile hemoglobin: the new alternative hemoglobin source for hemoglobin-based oxygen carriers | Full Text | References | PDF (1.4 MB) | EPUB
  • 3489 Views
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Article
Reliability of antioxidant potential and in vivo compatibility with extremophilic actinobacterial-mediated magnesium oxide nanoparticle synthesis
Kavitha Kandiah, Thenmozhi Jeevanantham & Balagurunathan Ramasamy
Pages: 862-872
Published online: 15 Mar 2019
AbstractforReliability of antioxidant potential and in vivo compatibility with extremophilic actinobacterial-mediated magnesium oxide nanoparticle synthesis | Full Text | References | PDF (1.7 MB) | EPUB
  • 2540 Views
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Article
Development and characterization of a novel conductive polyaniline-g-polystyrene/Fe3O4 nanocomposite for the treatment of cancer
Lida Ahmadkhani, Ebrahim Mostafavi, Samaneh Ghasemali, Roghayeh Baghban, Hamidreza Pazoki-Toroudi, Soodabeh Davaran, Javad Malakootikhah, Nahideh Asadi, Lala Mammadova, Siamak Saghfi, Thomas J. Webster & Abolfazl Akbarzadeh
Pages: 873-881
Published online: 15 Mar 2019
AbstractforDevelopment and characterization of a novel conductive polyaniline-g-polystyrene/Fe3O4 nanocomposite for the treatment of cancer | Full Text | References | PDF (1.6 MB) | EPUB
  • 2826 Views
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Review

Review
The use of stromal vascular fraction (SVF), platelet-rich plasma (PRP) and stem cells in the treatment of osteoarthritis: an overview of clinical trials
Sahar Mehranfar, Isa Abdi Rad, Ebrahim Mostafavi & Abolfazl Akbarzadeh
Pages: 882-890
Published online: 19 Mar 2019
AbstractforThe use of stromal vascular fraction (SVF), platelet-rich plasma (PRP) and stem cells in the treatment of osteoarthritis: an overview of clinical trials | Full Text | References | PDF (810.3 KB) | EPUB
  • 12644 Views
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Research Article

Article
Astaxanthin induces apoptosis and increases activity of antioxidant enzymes in LS-180 cells
Maryam Hormozi, Shadi Ghoreishi & Parasto Baharvand
Pages: 891-895
Published online: 15 Mar 2019
AbstractforAstaxanthin induces apoptosis and increases activity of antioxidant enzymes in LS-180 cells | Full Text | References | PDF (567.8 KB) | EPUB
  • 8803 Views
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Retracted Article

Article
RETRACTED ARTICLE: The biological function of long noncoding RNA FAL1 in oesophageal carcinoma cells
Zhiguo Yang, Dongyan Liu, Dan Wu, Fang Liu & Cuiping Liu
Pages: 896-903
Published online: 15 Mar 2019
AbstractforRETRACTED ARTICLE: The biological function of long noncoding RNA FAL1 in oesophageal carcinoma cells | PDF (2.2 MB)
  • 1360 Views
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Research Article

Article
Efficacy of Concanavalin-A conjugated nanotransfersomal gel of apigenin for enhanced targeted delivery of UV induced skin malignant melanoma
Manmohan S. Jangdey, Chanchal Deep Kaur & Swarnlata Saraf
Pages: 904-916
Published online: 11 Mar 2019
AbstractforEfficacy of Concanavalin-A conjugated nanotransfersomal gel of apigenin for enhanced targeted delivery of UV induced skin malignant melanoma | Full Text | References | PDF (1.3 MB) | EPUB
  • 2835 Views
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Article
Preparation of polyacrylamide/polylactic acid co-assembled core/shell nanofibers as designed beads for dapsone in vitro efficient delivery
Mehdi Ranjbar, Payam Khazaeli, Abbas Pardakhty, Batool Tahamipour & Arezou Amanatfard
Pages: 917-926
Published online: 11 Mar 2019
AbstractforPreparation of polyacrylamide/polylactic acid co-assembled core/shell nanofibers as designed beads for dapsone in vitro efficient delivery | Full Text | References | PDF (1.3 MB) | EPUB
  • 2063 Views
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Review

Review
Labour analgesia; Molecular pathway and the role of nanocarriers: a systematic review
Leila Kafshdooz, Houman Kahroba, Tayebeh Kafshdooz, Roghayeh Sheervalilou & Hojjat Pourfathi
Pages: 927-932
Published online: 15 Mar 2019
AbstractforLabour analgesia; Molecular pathway and the role of nanocarriers: a systematic review | Full Text | References | PDF (711.2 KB) | EPUB
  • 3398 Views
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Research Article

Article
Development and evaluation of doxorubicin self nanoemulsifying drug delivery system with Nigella Sativa oil against human hepatocellular carcinoma
Afreen Usmani, Anuradha Mishra, Md Arshad & Asif Jafri
Pages: 933-944
Published online: 19 Mar 2019
AbstractforDevelopment and evaluation of doxorubicin self nanoemulsifying drug delivery system with Nigella Sativa oil against human hepatocellular carcinoma | Full Text | References | PDF (1.4 MB) | EPUB
  • 4305 Views
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Original Articles

Article
Evaluation of Pistia stratiotes fractions as effective larvicide against Anopheles mosquitoes
Jincai Ma, Yunusa Adamu Ugya, Asma’u Isiyaku, Xiuyi Hua & Tijjani Sabiu Imam
Pages: 945-950
Published online: 11 Mar 2019
AbstractforEvaluation of Pistia stratiotes fractions as effective larvicide against Anopheles mosquitoes | Full Text | References | PDF (888.2 KB) | EPUB
  • 2793 Views
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Research Article

Article
Associations between IL-23R gene polymorphisms and the susceptibility of rheumatoid arthritis: a meta-analysis
Qinghua Zou, Yi Zhao, Yong Wang, Yongfei Fang & Yi Liu
Pages: 951-956
Published online: 11 Mar 2019
AbstractforAssociations between IL-23R gene polymorphisms and the susceptibility of rheumatoid arthritis: a meta-analysis | Full Text | References | PDF (752.5 KB) | EPUB
  • 2240 Views
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Article
Sustained release paclitaxel-loaded core-shell-structured solid lipid microparticles for intraperitoneal chemotherapy of ovarian cancer
Shuya Han, Pankaj Dwivedi, Farhana Akbar Mangrio, Monika Dwivedi, Renuka Khatik, David E. Cohn, Ting Si & Ronald X. Xu
Pages: 957-967
Published online: 20 Mar 2019
AbstractforSustained release paclitaxel-loaded core-shell-structured solid lipid microparticles for intraperitoneal chemotherapy of ovarian cancer | Full Text | References | PDF (1.6 MB) | EPUB
  • 2882 Views
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Article
Anti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy
Xueyuan Huang, Bin Wu, Jian Li, Yinghui Shang, Wansong Chen, Xinmin Nie & Rong Gui
Pages: 968-979
Published online: 18 Mar 2019
AbstractforAnti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy | Full Text | References | PDF (2.3 MB) | EPUB
  • 3502 Views
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Article
Accelerated infected wound healing by topical application of encapsulated Rosemary essential oil into nanostructured lipid carriers
Keyvan Khezri, Mohammad Reza Farahpour & Shokoofeh Mounesi Rad
Pages: 980-988
Published online: 11 Mar 2019
AbstractforAccelerated infected wound healing by topical application of encapsulated Rosemary essential oil into nanostructured lipid carriers | Full Text | References | PDF (1.4 MB) | EPUB
  • 8574 Views
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Article
Nano-erythrocyte membrane-chaperoned 5-fluorouracil liposomes as biomimetic delivery platforms to target hepatocellular carcinoma cell lines
Saeed A. AlQahtani, Gamaleldin I. Harisa, Mohamed M. Badran, Khalid M. AlGhamdi, Ashok Kumar, Mounir M. Salem-Bekhit, Sheikh F. Ahmad & Fars K. Alanazi
Pages: 989-996
Published online: 15 Mar 2019
AbstractforNano-erythrocyte membrane-chaperoned 5-fluorouracil liposomes as biomimetic delivery platforms to target hepatocellular carcinoma cell lines | Full Text | References | PDF (1.1 MB) | EPUB
  • 3549 Views
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Review

Review
ARTIFICIAL CELL evolves into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology
Thomas Ming Swi Chang
Pages: 997-1013
Published online: 04 Apr 2019
AbstractforARTIFICIAL CELL evolves into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology | Full Text | References | PDF (2.6 MB) | EPUB
  • 12726 Views
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Research Article

Article
Salidroside represses proliferation, migration and invasion of human lung cancer cells through AKT and MEK/ERK signal pathway
Mei Ren, Wenjing Xu & Tao Xu
Pages: 1014-1021
Published online: 18 Mar 2019
AbstractforSalidroside represses proliferation, migration and invasion of human lung cancer cells through AKT and MEK/ERK signal pathway | Full Text | References | PDF (1 MB) | EPUB
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Article
Engineered substrates with imprinted cell-like topographies induce direct differentiation of adipose-derived mesenchymal stem cells into Schwann cells
Mehrdad Moosazadeh Moghaddam, Shahin Bonakdar, Mohammad Ali Shokrgozar, Arash Zaminy, Hojatollah Vali & Shahab Faghihi
Pages: 1022-1035
Published online: 03 Apr 2019
AbstractforEngineered substrates with imprinted cell-like topographies induce direct differentiation of adipose-derived mesenchymal stem cells into Schwann cells | Full Text | References | PDF (2.7 MB) | EPUB
  • 3025 Views
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Article
Relationship between the expressions of PD-L1 and tumour-associated fibroblasts in gastric cancer
Linsong Mu, Wentao Yu, Hailong Su, Yang Lin, Wu Sui, Xiang Yu & Chengkun Qin
Pages: 1036-1042
Published online: 14 Apr 2019
AbstractforRelationship between the expressions of PD-L1 and tumour-associated fibroblasts in gastric cancer | Full Text | References | PDF (1,017 KB) | EPUB
  • 2967 Views
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Article
Salicin inhibits AGE-induced degradation of type II collagen and aggrecan in human SW1353 chondrocytes: therapeutic potential in osteoarthritis
Feng Gao & Shanyong Zhang
Pages: 1043-1049
Published online: 03 Apr 2019
AbstractforSalicin inhibits AGE-induced degradation of type II collagen and aggrecan in human SW1353 chondrocytes: therapeutic potential in osteoarthritis | Full Text | References | PDF (886.2 KB) | EPUB
  • 2711 Views
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Retracted Article

Article
RETRACTED ARTICLE: Kaempferol promotes proliferation, migration and differentiation of MC3T3-E1 cells via up-regulation of microRNA-101
Yang Wang, Hongyu Chen & Hanyang Zhang
Pages: 1050-1056
Published online: 03 Apr 2019
AbstractforRETRACTED ARTICLE: Kaempferol promotes proliferation, migration and differentiation of MC3T3-E1 cells via up-regulation of microRNA-101 | PDF (1.8 MB)
  • 2395 Views
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Original Paper

Article
Long non-coding RNA LINC00858 promotes cells proliferation, migration and invasion by acting as a ceRNA of miR-22-3p in colorectal cancer
Qian-Kun Sha, Lin Chen, Jia-Zhuang Xi & Hang Song
Pages: 1057-1066
Published online: 01 Apr 2019
AbstractforLong non-coding RNA LINC00858 promotes cells proliferation, migration and invasion by acting as a ceRNA of miR-22-3p in colorectal cancer | Full Text | References | PDF (1.4 MB) | EPUB
  • 2731 Views
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Research Article

Article
Vildagliptin inhibits high free fatty acid (FFA)-induced NLRP3 inflammasome activation in endothelial cells
Yanyan Qi, Xianhui Du, Xiangyan Yao & Yuanyuan Zhao
Pages: 1067-1074
Published online: 04 Apr 2019
AbstractforVildagliptin inhibits high free fatty acid (FFA)-induced NLRP3 inflammasome activation in endothelial cells | Full Text | References | PDF (970.5 KB) | EPUB
  • 3334 Views
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Article
Safeguarding the catalytic activity and stability of polyaniline chitosan silver nanocomposite bound beta-galactosidase against product inhibitors and structurally related compound
Maryam Khan & Qayyum Husain
Pages: 1075-1084
Published online: 03 Apr 2019
AbstractforSafeguarding the catalytic activity and stability of polyaniline chitosan silver nanocomposite bound beta-galactosidase against product inhibitors and structurally related compound | Full Text | References | PDF (1.6 MB) | EPUB
  • 1766 Views
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Article
Minicapsules encapsulating nanoparticles for targeting, apoptosis induction and treatment of colon cancer
Aakanchha Jain, Richa Jain, Sourabh Jain, Renuka Khatik & Dharam Veer Kohli
Pages: 1085-1093
Published online: 03 Apr 2019
AbstractforMinicapsules encapsulating nanoparticles for targeting, apoptosis induction and treatment of colon cancer | Full Text | References | PDF (1.1 MB) | EPUB
  • 2454 Views
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Article
Stem cells combined 3D electrospun nanofibrous and macrochannelled matrices: a preliminary approach in repair of rat cranial bones
İsmail Alper İşoğlu, Nimet Bölgen, Petek Korkusuz, İbrahim Vargel, Hakan Hamdi Çelik, Emine Kılıç, Elif Güzel, Tarık Çavuşoğlu, Duygu Uçkan & Erhan Pişkin
Pages: 1094-1100
Published online: 03 Apr 2019
AbstractforStem cells combined 3D electrospun nanofibrous and macrochannelled matrices: a preliminary approach in repair of rat cranial bones | Full Text | References | PDF (1.1 MB) | EPUB
  • 2123 Views
  • 8 CrossRef citations
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Article
Analysis of polymorphisms in genes associated with the FA/BRCA pathway in three patients with multiple primary malignant neoplasms
Le Wang, Hao Wang, Ting Wang, Jinhui Liu, Wei Chen, Yamin Wang, Chao Chen, Hongli Zhu & Penggao Dai
Pages: 1101-1112
Published online: 03 Apr 2019
AbstractforAnalysis of polymorphisms in genes associated with the FA/BRCA pathway in three patients with multiple primary malignant neoplasms | Full Text | References | PDF (1.4 MB) | EPUB
  • 3681 Views
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Article
Explorative analysis of the gene expression profile during liver regeneration of mouse: a microarray-based study
Li Yin, Yuanyuan Wang, Yingzi Lin, Guoying Yu & Qianfeng Xia
Pages: 1113-1121
Published online: 09 Apr 2019
AbstractforExplorative analysis of the gene expression profile during liver regeneration of mouse: a microarray-based study | Full Text | References | PDF (1.7 MB) | EPUB
  • 3862 Views
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Article
Biosynthesis of anti-leishmanial natural products in callus cultures of Artemisia scoparia
Reema Yousaf, Mubarak Ali Khan, Nazif Ullah, Imdad Khan, Obaid Hayat, Muhammad Aamir Shehzad, Irfan Khan, Faqeer Taj, Nizam Ud Din, Asghar Khan, Ijaz Naeem & Huma Ali
Pages: 1122-1131
Published online: 03 Apr 2019
AbstractforBiosynthesis of anti-leishmanial natural products in callus cultures of Artemisia scoparia | Full Text | References | PDF (1.1 MB) | EPUB
  • 2382 Views
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Review

Review
A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities
Seyyed Mojtaba Mousavi, Maryam Zarei, Seyyed Alireza Hashemi, Aziz Babapoor & Ali Mohammad Amani
Pages: 1132-1148
Published online: 03 Apr 2019
AbstractforA conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities | Full Text | References | PDF (2.1 MB) | EPUB
  • 7901 Views
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Review
Design, synthesis and characterization of enzyme-analogue-built polymer catalysts as artificial hydrolases
Divya Mathew, Benny Thomas & Karakkattu Subrahmanian Devaky
Pages: 1149-1172
Published online: 03 Apr 2019
AbstractforDesign, synthesis and characterization of enzyme-analogue-built polymer catalysts as artificial hydrolases | Full Text | References | PDF (3.2 MB) | EPUB
  • 3145 Views
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Research Article

Article
Synthesis and characterization of gold nanoparticles from aqueous leaf extract of Alternanthera sessilis and its anticancer activity on cervical cancer cells (HeLa)
Linhua Qian, Weihua Su, Yan Wang, Minyan Dang, Wenzhi Zhang & Changlin Wang
Pages: 1173-1180
Published online: 03 Apr 2019
AbstractforSynthesis and characterization of gold nanoparticles from aqueous leaf extract of Alternanthera sessilis and its anticancer activity on cervical cancer cells (HeLa) | Full Text | References | PDF (1.1 MB) | EPUB
  • 4264 Views
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Article
Improved antibacterial function of Rifampicin-loaded solid lipid nanoparticles on Brucella abortus
Jalal Ghaderkhani, Rasoul Yousefimashouf, Mohammadreza Arabestani, Ghodratollah Roshanaei, Sara Soleimani Asl & Roghayeh Abbasalipourkabir
Pages: 1181-1193
Published online: 03 Apr 2019
AbstractforImproved antibacterial function of Rifampicin-loaded solid lipid nanoparticles on Brucella abortus | Full Text | References | PDF (1.7 MB) | EPUB
  • 3815 Views
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Article
Antagonism of RIP1 using necrostatin-1 (Nec-1) ameliorated damage and inflammation of HBV X protein (HBx) in human normal hepatocytes
Linsen Xie & Yongjie Huang
Pages: 1194-1199
Published online: 09 Apr 2019
AbstractforAntagonism of RIP1 using necrostatin-1 (Nec-1) ameliorated damage and inflammation of HBV X protein (HBx) in human normal hepatocytes | Full Text | References | PDF (792 KB) | EPUB
  • 2398 Views
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Article
The mechanism of miR-16-5p protection on LPS-induced A549 cell injury by targeting CXCR3
Guo-Pan Liu, Wei-Wei Wang, Wen-Ying Lu & An-Quan Shang
Pages: 1200-1206
Published online: 08 Apr 2019
AbstractforThe mechanism of miR-16-5p protection on LPS-induced A549 cell injury by targeting CXCR3 | Full Text | References | PDF (987.8 KB) | EPUB
  • 2973 Views
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Retracted Article

Article
RETRACTED ARTICLE: Ras-ERK1/2 signalling promotes the development of osteosarcoma through regulation of H4K12ac through HAT1
Jingzhe Zhang, Meihan Liu, Wanguo Liu & Wenjun Wang
Pages: 1207-1215
Published online: 03 Apr 2019
AbstractforRETRACTED ARTICLE: Ras-ERK1/2 signalling promotes the development of osteosarcoma through regulation of H4K12ac through HAT1 | PDF (2.8 MB)
  • 1739 Views
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Research Article

Article
Synthesis of gold nanoparticles from leaf Panax notoginseng and its anticancer activity in pancreatic cancer PANC-1 cell lines
Lei Wang, Jianwei Xu, Ye Yan, Han Liu & Feng Li
Pages: 1216-1223
Published online: 03 Apr 2019
AbstractforSynthesis of gold nanoparticles from leaf Panax notoginseng and its anticancer activity in pancreatic cancer PANC-1 cell lines | Full Text | References | PDF (1.1 MB) | EPUB
  • 2824 Views
  • 33 CrossRef citations
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Article
Circular RNA (hsa_circ_0051240) promotes cell proliferation, migration and invasion in ovarian cancer through miR-637/KLK4 axis
Meiyin Zhang, Bairong Xia, Ye Xu, Yongjian Zhang, Jin Xu & Ge Lou
Pages: 1224-1233
Published online: 04 Apr 2019
AbstractforCircular RNA (hsa_circ_0051240) promotes cell proliferation, migration and invasion in ovarian cancer through miR-637/KLK4 axis | Full Text | References | PDF (1.7 MB) | EPUB
  • 3234 Views
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Retracted Article

Article
RETRACTED ARTICLE: LDH hybrid thermosensitive hydrogel for intravaginal delivery of anti-HIV drugs
Wenxue Tian, Shangcong Han, Xia Huang, Mei Han, Jie Cao, Yan Liang & Yong Sun
Pages: 1234-1240
Published online: 10 Apr 2019
AbstractforRETRACTED ARTICLE: LDH hybrid thermosensitive hydrogel for intravaginal delivery of anti-HIV drugs | PDF (2.6 MB)
  • 2096 Views
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Research Article

Article
LncRNA FOXD2-AS1 induces chondrocyte proliferation through sponging miR-27a-3p in osteoarthritis
Yang Wang, Lei Cao, Qiugen Wang, Jianhua Huang & Shuogui Xu
Pages: 1241-1247
Published online: 04 Apr 2019
AbstractforLncRNA FOXD2-AS1 induces chondrocyte proliferation through sponging miR-27a-3p in osteoarthritis | Full Text | References | PDF (1,021.3 KB) | EPUB
  • 2263 Views
  • 40 CrossRef citations
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Article
pPolyHb protects myocardial H9C2 cells against ischemia-reperfusion injury by regulating the Pink1-Parkin-mediated mitochondrial autophagy pathway
Wenjin Zhu, Fang Liu, Li Wang, Bo Yang, Yuwei Bai, Yanzhi Huang, Yaru Li, Wei Li, Yuemin Yuan, Chao Chen & Hongli Zhu
Pages: 1248-1255
Published online: 04 Apr 2019
AbstractforpPolyHb protects myocardial H9C2 cells against ischemia-reperfusion injury by regulating the Pink1-Parkin-mediated mitochondrial autophagy pathway | Full Text | References | PDF (1.1 MB) | EPUB
  • 2830 Views
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Article
Lixisenatide attenuates advanced glycation end products (AGEs)-induced degradation of extracellular matrix in human primary chondrocytes
Xin Li, Fangteng Jia, Zhengqing Zhu & Lanfeng Huang
Pages: 1256-1264
Published online: 03 Apr 2019
AbstractforLixisenatide attenuates advanced glycation end products (AGEs)-induced degradation of extracellular matrix in human primary chondrocytes | Full Text | References | PDF (1 MB) | EPUB
  • 2247 Views
  • 10 CrossRef citations
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Article
Propofol inhibits proliferation and epithelial-mesenchymal transition of MCF-7 cells by suppressing miR-21 expression
Qing Du, Xuezhi Zhang, Xin Zhang, Ming Wei, Hongmei Xu & Shilei Wang
Pages: 1265-1271
Published online: 03 Apr 2019
AbstractforPropofol inhibits proliferation and epithelial-mesenchymal transition of MCF-7 cells by suppressing miR-21 expression | Full Text | References | PDF (926.7 KB) | EPUB
  • 2618 Views
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Correction

Correction
Correction
Page: 1272
Published online: 03 Apr 2019
CitationforCorrection | Full Text | PDF (152.6 KB) | EPUB
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Research Article

Article
Inhibition of SF3b1 by pladienolide B evokes cycle arrest, apoptosis induction and p73 splicing in human cervical carcinoma cells
Qianjing Zhang, Cuixia Di, Junfang Yan, Fang Wang, Tao Qu, Yupei Wang, Yuhong Chen, Xuetian Zhang, Yang Liu, Hongying Yang & Hong Zhang
Pages: 1273-1280
Published online: 09 Apr 2019
AbstractforInhibition of SF3b1 by pladienolide B evokes cycle arrest, apoptosis induction and p73 splicing in human cervical carcinoma cells | Full Text | References | PDF (1.2 MB) | EPUB
  • 5533 Views
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Article
The effects of histamine H1 type receptor (H1R) in regulating osteoblastic cell differentiation and mineralization
Yanpeng Sun, Xiaodong Peng, Yanzhou Li, Husheng Ma, Dongfang Li & Xiangqin Shi
Pages: 1281-1287
Published online: 03 Apr 2019
AbstractforThe effects of histamine H1 type receptor (H1R) in regulating osteoblastic cell differentiation and mineralization | Full Text | References | PDF (893.1 KB) | EPUB
  • 1994 Views
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Article
The protective effects of saxagliptin against lipopolysaccharide (LPS)-induced inflammation and damage in human dental pulp cells
Xinxing Guo & Jing Chen
Pages: 1288-1294
Published online: 03 Apr 2019
AbstractforThe protective effects of saxagliptin against lipopolysaccharide (LPS)-induced inflammation and damage in human dental pulp cells | Full Text | References | PDF (899.8 KB) | EPUB
  • 2894 Views
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Original Articles

Article
Development and characterization of a novel cationic PEGylated niosome-encapsulated forms of doxorubicin, quercetin and siRNA for the treatment of cancer by using combination therapy
Mahdie Hemati, Fateme Haghiralsadat, Fatemeh Yazdian, Farzaneh Jafari, Ali Moradi & Zahra Malekpour-Dehkordi
Pages: 1295-1311
Published online: 22 Jul 2018
AbstractforDevelopment and characterization of a novel cationic PEGylated niosome-encapsulated forms of doxorubicin, quercetin and siRNA for the treatment of cancer by using combination therapy | Full Text | References | PDF (2.7 MB) | EPUB
  • 5390 Views
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Review

Review
Nanoparticle-based drug delivery in the inner ear: current challenges, limitations and opportunities
Rahul Mittal, Stefanie A. Pena, Angela Zhu, Nicolas Eshraghi, Arian Fesharaki, Elijah J. Horesh, Jeenu Mittal & Adrien A. Eshraghi
Pages: 1312-1320
Published online: 15 Apr 2019
AbstractforNanoparticle-based drug delivery in the inner ear: current challenges, limitations and opportunities | Full Text | References | PDF (1.1 MB) | EPUB
  • 6677 Views
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Research Article

Article
Synthesis of photoluminescent carbon dots and its effect on chondrocytes for knee joint therapy applications
Rui Sun & Shichao Liu
Pages: 1321-1325
Published online: 22 Apr 2019
AbstractforSynthesis of photoluminescent carbon dots and its effect on chondrocytes for knee joint therapy applications | Full Text | References | PDF (783.1 KB) | EPUB
  • 2132 Views
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Article
Photosensitizer effects of MWCNTs-COOH particles on CT26 fibroblastic cells exposed to laser irradiation
Nouraddin Abdi Goushbolagh, Marzieh Keshavarz, Mohammad Hosein Zare, Mohammad Hossein Bahreyni-Toosi, Masoud Kargar & Bagher Farhood
Pages: 1326-1334
Published online: 09 Apr 2019
AbstractforPhotosensitizer effects of MWCNTs-COOH particles on CT26 fibroblastic cells exposed to laser irradiation | Full Text | References | PDF (1.4 MB) | EPUB
  • 1675 Views
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Article
IL-33 drives the antitumour effects of dendritic cells via upregulating CYLD expression in pulmonary adenocarcinoma
Jiguang Zhang, Yangming Chen, Kai Chen, Yunchao Huang, Xunyu Xu, Qianshun Chen, Chen Huang, Jiewei Luo & Xing Lin
Pages: 1335-1341
Published online: 09 Apr 2019
AbstractforIL-33 drives the antitumour effects of dendritic cells via upregulating CYLD expression in pulmonary adenocarcinoma | Full Text | References | PDF (864.7 KB) | EPUB
  • 2449 Views
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Article
LncRNA HIF2PUT inhibited osteosarcoma stem cells proliferation, migration and invasion by regulating HIF2 expression
Ding Zhao, Sisi Wang, Xu Chu & Dongfeng Han
Pages: 1342-1348
Published online: 10 Apr 2019
AbstractforLncRNA HIF2PUT inhibited osteosarcoma stem cells proliferation, migration and invasion by regulating HIF2 expression | Full Text | References | PDF (1 MB) | EPUB
  • 2550 Views
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Article
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer
Jiayin Sun, Hui Zhang, Dan Tao, Fei Xie, Feng Liu, Chaohui Gu, Miao Wang, Liang Wang, Guosong Jiang, Zhendi Wang & Xingyuan Xiao
Pages: 1349-1356
Published online: 10 Apr 2019
AbstractforCircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer | Full Text | References | PDF (1.3 MB) | EPUB
  • 2992 Views
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Article
The therapeutic effect of secretome from human umbilical cord-derived mesenchymal stem cells in age-related osteoporosis
Min Liang, Wanguo Liu, Zhibin Peng, Shihong Lv, Ying Guan, Gang An, Yubo Zhang, Tianwen Huang & Yansong Wang
Pages: 1357-1366
Published online: 12 Apr 2019
AbstractforThe therapeutic effect of secretome from human umbilical cord-derived mesenchymal stem cells in age-related osteoporosis | Full Text | References | PDF (1.5 MB) | EPUB
  • 4297 Views
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Article
Biogenic zinc oxide nanoparticles-enhanced biosynthesis of lignans and neolignans in cell suspension cultures of Linum usitatissimum L
Bilal Haider Abbasi, Adnan Zahir, Waqar Ahmad, Muhammad Nadeem, Nathalie Giglioli-Guivarc’h & Christophe Hano
Pages: 1367-1373
Published online: 28 May 2019
AbstractforBiogenic zinc oxide nanoparticles-enhanced biosynthesis of lignans and neolignans in cell suspension cultures of Linum usitatissimum L | Full Text | References | PDF (1.3 MB) | EPUB
  • 3070 Views
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Article
Co-delivery of sorafenib and VEGF-siRNA via pH-sensitive liposomes for the synergistic treatment of hepatocellular carcinoma
Yao Yao, Tianqi Wang, Yongjun Liu & Na Zhang
Pages: 1374-1383
Published online: 12 Apr 2019
AbstractforCo-delivery of sorafenib and VEGF-siRNA via pH-sensitive liposomes for the synergistic treatment of hepatocellular carcinoma | Full Text | References | PDF (1.6 MB) | EPUB
  • 4553 Views
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Article
LncRNA ANRIL protects against oxygen and glucose deprivation (OGD)-induced injury in PC-12 cells: potential role in ischaemic stroke
Bin Liu, Wei Cao & Jian Xue
Pages: 1384-1395
Published online: 23 Apr 2019
AbstractforLncRNA ANRIL protects against oxygen and glucose deprivation (OGD)-induced injury in PC-12 cells: potential role in ischaemic stroke | Full Text | References | PDF (1.6 MB) | EPUB
  • 2424 Views
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Article
Using CuO nanoparticles and hyperthermia in radiotherapy of MCF-7 cell line: synergistic effect in cancer therapy
Hadi Esmaeili Govarchin Ghaleh, Leila Zarei, Bahman Mansori Motlagh & Nasrollah Jabbari
Pages: 1396-1403
Published online: 09 Apr 2019
AbstractforUsing CuO nanoparticles and hyperthermia in radiotherapy of MCF-7 cell line: synergistic effect in cancer therapy | Full Text | References | PDF (822.3 KB) | EPUB
  • 2726 Views
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Article
Production of Hypericum perforatum oil-loaded membranes for wound dressing material and in vitro tests
Özlem Eğri & Name Erdemir
Pages: 1404-1415
Published online: 04 Apr 2019
AbstractforProduction of Hypericum perforatum oil-loaded membranes for wound dressing material and in vitro tests | Full Text | References | PDF (1.9 MB) | EPUB
  • 4035 Views
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Article
Netrin-1 plays a critical role in regulating capacities of epidermal stem cells upon ultraviolet-B (UV-B) irradiation
Peng Wu, Yongqian Cao, Ran Zhao & Yibing Wang
Pages: 1416-1422
Published online: 23 Apr 2019
AbstractforNetrin-1 plays a critical role in regulating capacities of epidermal stem cells upon ultraviolet-B (UV-B) irradiation | Full Text | References | PDF (892.1 KB) | EPUB
  • 2124 Views
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Article
Association between NOS3 polymorphisms and osteonecrosis of the femoral head
Xiaodong Zhao, Fuqiang Yang, Luwei Sun & Ali Zhang
Pages: 1423-1427
Published online: 22 Apr 2019
AbstractforAssociation between NOS3 polymorphisms and osteonecrosis of the femoral head | Full Text | References | PDF (494.4 KB) | EPUB
  • 1793 Views
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Article
Comparative in vitro transportation of pentamidine across the blood-brain barrier using polycaprolactone nanoparticles and phosphatidylcholine liposomes
Geofrey Omarch, Yunus Kippie, Shireen Mentor, Naushaad Ebrahim, David Fisher, Grace Murilla, Hulda Swai & Admire Dube
Pages: 1428-1436
Published online: 22 Apr 2019
AbstractforComparative in vitro transportation of pentamidine across the blood-brain barrier using polycaprolactone nanoparticles and phosphatidylcholine liposomes | Full Text | References | PDF (1.1 MB) | EPUB
  • 2699 Views
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Article
pH-responsive carbon nanotube-based hybrid nanogels as the smart anticancer drug carrier
Amir Seyfoori, Sara Sarfarazijami & S. A. Seyyed Ebrahimi
Pages: 1437-1443
Published online: 16 Apr 2019
AbstractforpH-responsive carbon nanotube-based hybrid nanogels as the smart anticancer drug carrier | Full Text | References | PDF (1.1 MB) | EPUB
  • 3126 Views
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Retracted Article

Article
RETRACTED ARTICLE: Long non-coding RNA SNHG16 reduces hydrogen peroxide-induced cell injury in PC-12 cells by up-regulating microRNA-423-5p
Haochuan Liu, Bing Chen & Qingsan Zhu
Pages: 1444-1451
Published online: 12 Apr 2019
AbstractforRETRACTED ARTICLE: Long non-coding RNA SNHG16 reduces hydrogen peroxide-induced cell injury in PC-12 cells by up-regulating microRNA-423-5p | PDF (2.1 MB)
  • 1702 Views
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Research Article

Article
Effects of bronchial provocation test and bronchial dilation test for the diagnosis of lung diseases
Mingxia Feng, Xuemei Yang & Yong He
Pages: 1452-1457
Published online: 22 Apr 2019
AbstractforEffects of bronchial provocation test and bronchial dilation test for the diagnosis of lung diseases | Full Text | References | PDF (551.6 KB) | EPUB
  • 2149 Views
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Article
Knocking down miR-384 promotes growth and metastasis of osteosarcoma MG63 cells by targeting SLBP
Yang Wang, Hong Huang & Yi Li
Pages: 1458-1465
Published online: 22 Apr 2019
AbstractforKnocking down miR-384 promotes growth and metastasis of osteosarcoma MG63 cells by targeting SLBP | Full Text | References | PDF (1.2 MB) | EPUB
  • 2444 Views
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Retracted Article

Article
RETRACTED ARTICLE: Expression tendency and prognostic value of TCF21 in hepatocellular carcinoma
Wei Lu, Chao Yang, Peng Du, Jun-Li Zhang & Jia-Cheng Zhang
Pages: 1466-1470
Published online: 24 Apr 2019
AbstractforRETRACTED ARTICLE: Expression tendency and prognostic value of TCF21 in hepatocellular carcinoma | PDF (1.4 MB)
  • 1357 Views
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Article
RETRACTED ARTICLE: Association of the polymorphisms in FOXO1 gene and diabetic nephropathy risk
Jianxia Ma, Yongbin Pei, Peng Xue, Yan Wang, Xiaoxue Bao & Yukun Li
Pages: 1471-1475
Published online: 15 Apr 2019
AbstractforRETRACTED ARTICLE: Association of the polymorphisms in FOXO1 gene and diabetic nephropathy risk | PDF (1.2 MB)
  • 1585 Views
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Review

Review
Intelligent polymeric micelles for multidrug co-delivery and cancer therapy
Guangping Yu, Qian Ning, Zhongcheng Mo & Shengsong Tang
Pages: 1476-1487
Published online: 09 May 2019
AbstractforIntelligent polymeric micelles for multidrug co-delivery and cancer therapy | Full Text | References | PDF (1.1 MB) | EPUB
  • 4669 Views
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Research Article

Article
Biosynthesis, characterization and antibacterial activity of silver nanoparticles by the Arctic anti-oxidative bacterium Paracoccus sp. Arc7-R13
Zheng Zhang, Shuang Li, Xiaoqian Gu, Jiang Li & Xuezheng Lin
Pages: 1488-1495
Published online: 16 Apr 2019
AbstractforBiosynthesis, characterization and antibacterial activity of silver nanoparticles by the Arctic anti-oxidative bacterium Paracoccus sp. Arc7-R13 | Full Text | References | PDF (1.1 MB) | EPUB
  • 1835 Views
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Article
A novel cross-linked haemoglobin-based oxygen carrier is beneficial to sepsis in rats
Lei Kuang, Yu Zhu, Jie Zhang, Yue Wu, Kunlun Tian, Xiangyun Chen, Mingying Xue, Fei Chuen Tzang, Billi Lau, Bing Lou Wong, Liangming Liu & Tao Li
Pages: 1496-1504
Published online: 14 Apr 2019
AbstractforA novel cross-linked haemoglobin-based oxygen carrier is beneficial to sepsis in rats | Full Text | References | PDF (1.5 MB) | EPUB
  • 2781 Views
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Article
Determination and pharmacokinetic study of isothiouronium-modified pyrimidine-substituted curcumin analog (1G), a novel antitumor agent, in rat plasma by liquid chromatography–tandem mass spectrometry
Jialin Sun, Jinpeng Wang, Lin Ma, Tao Jiang, Xiao Li, Qie Guo, Xiangpeng Li & Zhongguo Sui
Pages: 1505-1512
Published online: 16 Apr 2019
AbstractforDetermination and pharmacokinetic study of isothiouronium-modified pyrimidine-substituted curcumin analog (1G), a novel antitumor agent, in rat plasma by liquid chromatography–tandem mass spectrometry | Full Text | References | PDF (1.6 MB) | EPUB
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Article
Downregulated MEG3 contributes to tumour progression and poor prognosis in oesophagal squamous cell carcinoma by interacting with miR-4261, downregulating DKK2 and activating the Wnt/β-catenin signalling
Ji Ma, Teng-Fei Li, Xin-Wei Han & Hui-Feng Yuan
Pages: 1513-1523
Published online: 16 Apr 2019
AbstractforDownregulated MEG3 contributes to tumour progression and poor prognosis in oesophagal squamous cell carcinoma by interacting with miR-4261, downregulating DKK2 and activating the Wnt/β-catenin signalling | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Geniposide alleviates lipopolysaccharide-caused apoptosis of murine kidney podocytes by activating Ras/Raf/MEK/ERK-mediated cell autophagy
Xia Li, Aijing Ma & Kun Liu
Pages: 1524-1532
Published online: 13 Apr 2019
AbstractforGeniposide alleviates lipopolysaccharide-caused apoptosis of murine kidney podocytes by activating Ras/Raf/MEK/ERK-mediated cell autophagy | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Targeted delivery of poly (methyl methacrylate) particles in colon cancer cells selectively attenuates cancer cell proliferation
Firdos Alam Khan, Sultan Akhtar, Dana Almohazey, Munther Alomari, Sarah Ameen Almofty, Ibrahim Badr & Abdelhamid Elaissari
Pages: 1533-1542
Published online: 22 Apr 2019
AbstractforTargeted delivery of poly (methyl methacrylate) particles in colon cancer cells selectively attenuates cancer cell proliferation | Full Text | References | PDF (1.9 MB) | EPUB
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Article
HBs antigen and mannose loading on the surface of iron oxide nanoparticles in order to immuno-targeting: fabrication, characterization, cellular and humoral immunoassay
Mahsa Rezaei, Seyed Nezamedin Hosseini, Ramazan Ali Khavari-Nejad, Farhood Najafi & Mehdi Mahdavi
Pages: 1543-1558
Published online: 22 Apr 2019
AbstractforHBs antigen and mannose loading on the surface of iron oxide nanoparticles in order to immuno-targeting: fabrication, characterization, cellular and humoral immunoassay | Full Text | References | PDF (2.4 MB) | EPUB
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Article
Optimization of composite cryoprotectant for freeze-drying Bifidobacterium bifidum BB01 by response surface methodology
He Chen, Mengqi Tian, Li Chen, Xiuxiu Cui, Jiangpeng Meng & Guowei Shu
Pages: 1559-1569
Published online: 22 Apr 2019
AbstractforOptimization of composite cryoprotectant for freeze-drying Bifidobacterium bifidum BB01 by response surface methodology | Full Text | References | PDF (1.8 MB) | EPUB
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Article
Allogenic chondrocyte/osteoblast-loaded β-tricalcium phosphate bioceramic scaffolds for articular cartilage defect treatment
Shuai Wu, Zhiguo Kai, Dong Wang, Lina Tao, Peng Zhang, Dawei Wang, Dongxing Liu, Shui Sun & Jian Zhong
Pages: 1570-1576
Published online: 22 Apr 2019
AbstractforAllogenic chondrocyte/osteoblast-loaded β-tricalcium phosphate bioceramic scaffolds for articular cartilage defect treatment | Full Text | References | PDF (2.1 MB) | EPUB
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Article
Comparative characterization of mesenchymal stem cells from human dental pulp and adipose tissue for bone regeneration potential
Qiaoqiao Jin, Keyong Yuan, Wenzhen Lin, Chenguang Niu, Rui Ma & Zhengwei Huang
Pages: 1577-1584
Published online: 26 Apr 2019
AbstractforComparative characterization of mesenchymal stem cells from human dental pulp and adipose tissue for bone regeneration potential | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Transplantation of mouse iPSCs into testis of azoospermic mouse model: in vivo and in vitro study
Forouzan Rahmani, Mansoureh Movahedin, Zohreh Mazaheri & Masoud Soleimani
Pages: 1585-1594
Published online: 22 Apr 2019
AbstractforTransplantation of mouse iPSCs into testis of azoospermic mouse model: in vivo and in vitro study | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Long noncoding RNA LINC-PINT inhibits non-small cell lung cancer progression through sponging miR-218-5p/PDCD4
Libin Zhang, Jing Hu, Jiagui Li, Qiuju Yang, Menghui Hao & Liang Bu
Pages: 1595-1602
Published online: 23 Apr 2019
AbstractforLong noncoding RNA LINC-PINT inhibits non-small cell lung cancer progression through sponging miR-218-5p/PDCD4 | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Cytotoxic and apoptotic properties of silver chloride nanoparticles synthesized using Escherichia coli cell-free supernatant on human breast cancer MCF 7 cell line
Razieh Bigdeli, Masoumeh Shahnazari, Erfan Panahnejad, Reza Ahangari Cohan, Aziz Dashbolaghi & Vahid Asgary
Pages: 1603-1609
Published online: 26 Apr 2019
AbstractforCytotoxic and apoptotic properties of silver chloride nanoparticles synthesized using Escherichia coli cell-free supernatant on human breast cancer MCF 7 cell line | Full Text | References | PDF (922.1 KB) | EPUB
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Article
Gold nano particles synthesized from Strychni semen and its anticancer activity in cholangiocarcinoma cell (KMCH-1)
Yuehua Li, Yang Ke, Hao Zou, Kun Wang, Songquan Huang, Thamaraiselvan Rengarajan & Lin Wang
Pages: 1610-1616
Published online: 10 May 2019
AbstractforGold nano particles synthesized from Strychni semen and its anticancer activity in cholangiocarcinoma cell (KMCH-1) | Full Text | References | PDF (968.8 KB) | EPUB
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Article
Green synthesis of gold nanoparticles from Scutellaria barbata and its anticancer activity in pancreatic cancer cell (PANC‐1)
Lei Wang, Jianwei Xu, Ye Yan, Han Liu, Thiruventhan Karunakaran & Feng Li
Pages: 1617-1627
Published online: 24 Apr 2019
AbstractforGreen synthesis of gold nanoparticles from Scutellaria barbata and its anticancer activity in pancreatic cancer cell (PANC‐1) | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Antagonism of NK-1R using aprepitant suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes
Xiaoping Liu, Yuelan Zhu, Wei Zheng, Tangliang Qian, Haiyu Wang & Xiujuan Hou
Pages: 1628-1634
Published online: 23 Apr 2019
AbstractforAntagonism of NK-1R using aprepitant suppresses inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes | Full Text | References | PDF (879.1 KB) | EPUB
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Article
Cancer cell membrane cloaking nanoparticles for targeted co-delivery of doxorubicin and PD-L1 siRNA
Mushi Chen, Ming Chen & Jiantai He
Pages: 1635-1641
Published online: 26 Apr 2019
AbstractforCancer cell membrane cloaking nanoparticles for targeted co-delivery of doxorubicin and PD-L1 siRNA | Full Text | References | PDF (911.8 KB) | EPUB
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Article
The effect of chrysin–curcumin-loaded nanofibres on the wound-healing process in male rats
Zoheyr Mohammadi, Mohsen Sharif Zak, Hasan Majdi, Ebrahim Mostafavi, Meisam Barati, Hamid Lotfimehr, Kambiz Ghaseminasab, Hamidreza Pazoki-Toroudi, Thomas J. Webster & Abolfazl Akbarzadeh
Pages: 1642-1652
Published online: 26 Apr 2019
AbstractforThe effect of chrysin–curcumin-loaded nanofibres on the wound-healing process in male rats | Full Text | References | PDF (1.7 MB) | EPUB
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Article
6-Gingerols (6G) reduces hypoxia-induced PC-12 cells apoptosis and autophagy through regulation of miR-103/BNIP3
Chunyang Kang, Mingyang Kang, Yingying Han, Tuo Zhang, Wei Quan & Jian Gao
Pages: 1653-1661
Published online: 02 May 2019
Abstractfor6-Gingerols (6G) reduces hypoxia-induced PC-12 cells apoptosis and autophagy through regulation of miR-103/BNIP3 | Full Text | References | PDF (1.2 MB) | EPUB
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Article
BMP-2-releasing gelatin microspheres/PLGA scaffolds for bone repairment of X-ray-radiated rabbit radius defects
Peng Xia, Song Wang, Zhiping Qi, Wei Zhang & Yifu Sun
Pages: 1662-1673
Published online: 29 Apr 2019
AbstractforBMP-2-releasing gelatin microspheres/PLGA scaffolds for bone repairment of X-ray-radiated rabbit radius defects | Full Text | References | PDF (1.8 MB) | EPUB
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Review
Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview
Muhammad Asim Farooq, Md Aquib, Anum Farooq, Daulat Haleem Khan, Mily Bazezy Joelle Maviah, Mensura Sied Filli, Samuel Kesse, Kofi Oti Boakye-Yiadom, Rukhshona Mavlyanova, Amna Parveen & Bo Wang
Pages: 1674-1692
Published online: 08 May 2019
AbstractforRecent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview | Full Text | References | PDF (1.5 MB) | EPUB
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Research Article

Article
Adipose tissue-derived ECM hydrogels and their use as 3D culture scaffold
Vasilena E. Getova, Joris A. van Dongen, Linda A. Brouwer & Martin C. Harmsen
Pages: 1693-1701
Published online: 07 May 2019
AbstractforAdipose tissue-derived ECM hydrogels and their use as 3D culture scaffold | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Synthesis and evaluation of hydrophobically modified fenugreek gum for potential hepatic drug delivery
Minghui Zhou, Boli Li, Xinhui Zhang, Shaolong He, Yanni Ma & Wenping Wang
Pages: 1702-1709
Published online: 07 May 2019
AbstractforSynthesis and evaluation of hydrophobically modified fenugreek gum for potential hepatic drug delivery | Full Text | References | PDF (1.7 MB) | EPUB
  • 1491 Views
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Article
Biomimetic cartilage scaffold with orientated porous structure of two factors for cartilage repair of knee osteoarthritis
Jianhua Wang, Yingying Wang, Xiaomin Sun, Deshuai Liu, Chenguang Huang, Jiulin Wu, Chunrong Yang & Qiqing Zhang
Pages: 1710-1721
Published online: 07 May 2019
AbstractforBiomimetic cartilage scaffold with orientated porous structure of two factors for cartilage repair of knee osteoarthritis | Full Text | References | PDF (3.5 MB) | EPUB
  • 4769 Views
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Article
MicroRNA-10b controls the metastasis and proliferation of colorectal cancer cells by regulating Krüppel-like factor 4
Yue Xie, Jing Zhao, Yanling Liang, Min Chen, Yihong Luo, Xiaobing Cui, Bo Jiang, Liang Peng & Xinying Wang
Pages: 1722-1729
Published online: 29 Apr 2019
AbstractforMicroRNA-10b controls the metastasis and proliferation of colorectal cancer cells by regulating Krüppel-like factor 4 | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Long noncoding RNA SBF2-AS1 act as a ceRNA to modulate cell proliferation via binding with miR-188-5p in acute myeloid leukemia
Yun-Jiao Tian, Yan-Hua Wang, Ai-Ju Xiao, Pei-Ling Li, Jia Guo, Tuan-Jie Wang & Dong-Ju Zhao
Pages: 1730-1737
Published online: 07 May 2019
AbstractforLong noncoding RNA SBF2-AS1 act as a ceRNA to modulate cell proliferation via binding with miR-188-5p in acute myeloid leukemia | Full Text | References | PDF (1 MB) | EPUB
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Article
Propofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells
Hai Sun, Yingjian Wang & Wenyu Zhang
Pages: 1738-1745
Published online: 03 May 2019
AbstractforPropofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells | Full Text | References | PDF (928.5 KB) | EPUB
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Co-SLD suppressed the growth of oral squamous cell carcinoma via disrupting mitochondrial function
Sirui Li, Guo Li, Taofeng Zhang, Jili Li, Quanyi Zhao, Baoping Zhang, Rui Wang, Rong Zhou, Jing Si, Lu Gan, Yang Liu, Hong Zhang & Bin Liu
Pages: 1746-1757
Published online: 07 May 2019
AbstractforCo-SLD suppressed the growth of oral squamous cell carcinoma via disrupting mitochondrial function | Full Text | References | PDF (1.6 MB) | EPUB
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Article
Salidroside mitigates hydrogen peroxide-induced injury by enhancement of microRNA-27a in human trabecular meshwork cells
Jun Zhao, Xiujuan Du, Meng Wang, Peiyao Yang & Juanmei Zhang
Pages: 1758-1765
Published online: 07 May 2019
AbstractforSalidroside mitigates hydrogen peroxide-induced injury by enhancement of microRNA-27a in human trabecular meshwork cells | Full Text | References | PDF (1.1 MB) | EPUB
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MicroRNA-27b-3p inhibits apoptosis of chondrocyte in rheumatoid arthritis by targeting HIPK2
Yizhao Zhou, Sihong Li, Ping Chen, Benyu Yang, Junjun Yang, Renfeng Liu, Jiamiao Li & Duo Xia
Pages: 1766-1771
Published online: 08 May 2019
AbstractforMicroRNA-27b-3p inhibits apoptosis of chondrocyte in rheumatoid arthritis by targeting HIPK2 | Full Text | References | PDF (744.5 KB) | EPUB
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Differentiation of spermatogonial stem cells by soft agar three-dimensional culture system
Elham Mohammadzadeh, Tooba Mirzapour, Mohammad Reza Nowroozi, Hamid Nazarian, Abbas Piryaei, Fatemeh Alipour, Sayed Mostafa Modarres Mousavi & Marefat Ghaffari Novin
Pages: 1772-1781
Published online: 26 May 2019
AbstractforDifferentiation of spermatogonial stem cells by soft agar three-dimensional culture system | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Long non-coding RNA NEAT1 promotes steatosis via enhancement of estrogen receptor alpha-mediated AQP7 expression in HepG2 cells
Xiaohua Fu, Jing Zhu, Lin Zhang & Jing Shu
Pages: 1782-1787
Published online: 07 May 2019
AbstractforLong non-coding RNA NEAT1 promotes steatosis via enhancement of estrogen receptor alpha-mediated AQP7 expression in HepG2 cells | Full Text | References | PDF (829.1 KB) | EPUB
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The role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity
Yan Chen, Lili Yan, Yan Zhang & Xianhui Yang
Pages: 1788-1796
Published online: 07 May 2019
AbstractforThe role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity | Full Text | References | PDF (1.1 MB) | EPUB
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Scutellaria barbata D. Don (SBD) protects oxygen glucose deprivation/reperfusion-induced injuries of PC12 cells by up-regulating Nrf2
Yanhua Wang, Bo Li & Xiaofen Zhang
Pages: 1797-1807
Published online: 07 May 2019
AbstractforScutellaria barbata D. Don (SBD) protects oxygen glucose deprivation/reperfusion-induced injuries of PC12 cells by up-regulating Nrf2 | Full Text | References | PDF (1.8 MB) | EPUB
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Article
Notoginsenoside R1 alleviates lipopolysaccharide-triggered PC-12 inflammatory damage via elevating microRNA-132
Yuanliang Sun, Bing Liu, Xiujun Zheng & Dechun Wang
Pages: 1808-1814
Published online: 07 May 2019
AbstractforNotoginsenoside R1 alleviates lipopolysaccharide-triggered PC-12 inflammatory damage via elevating microRNA-132 | Full Text | References | PDF (896.8 KB) | EPUB
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Article
Long non-coding RNA UCA1 exerts growth modulation by miR-15a in human thyroid cancer TPC-1 cells
Dandan Li, Shuai Hao & Jing Zhang
Pages: 1815-1822
Published online: 07 May 2019
AbstractforLong non-coding RNA UCA1 exerts growth modulation by miR-15a in human thyroid cancer TPC-1 cells | Full Text | References | PDF (1.1 MB) | EPUB
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Article
The dosage effects of dexamethasone on osteogenic activity andbiocompatibility of poly(lactic-co-glycolic acid)/hydroxyapatite nanofibers
Chang Li, Bo Wang, Xinchen Liu, Ziyi Pan, Chao Liu, Huayu Ma, Xueyan Liu, Lijun Liu & Chao Jiang
Pages: 1823-1832
Published online: 08 May 2019
AbstractforThe dosage effects of dexamethasone on osteogenic activity andbiocompatibility of poly(lactic-co-glycolic acid)/hydroxyapatite nanofibers | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Cell division cycle protein 42 regulates the inflammatory response in mice bearing inflammatory bowel disease
Le-Mei Dong, Xiao-Wei Chen, Xi-Xi He, Xue-Pei Jiang & Fang Wu
Pages: 1833-1838
Published online: 07 May 2019
AbstractforCell division cycle protein 42 regulates the inflammatory response in mice bearing inflammatory bowel disease | Full Text | References | PDF (933.3 KB) | EPUB
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The antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation
Yun Kuang, Hui Liu, Siyu Guo, Yufei Wang, Huijuan Zhang & Yanxiang Qiao
Pages: 1839-1845
Published online: 08 May 2019
AbstractforThe antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation | Full Text | References | PDF (961.7 KB) | EPUB
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Toxicity of microwave-assisted biosynthesized zinc nanoparticles in mice: a preliminary study
Azad Salimi, Hamid-Reza Rahimi, Hamid Forootanfar, Elham Jafari, Atefeh Ameri & Mojtaba Shakibaie
Pages: 1846-1858
Published online: 08 May 2019
AbstractforToxicity of microwave-assisted biosynthesized zinc nanoparticles in mice: a preliminary study | Full Text | References | PDF (2.3 MB) | EPUB
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Article

Article
The potential value of lncRNA-BC050642 in osteosarcoma origination and outcomes
Yang Yang, Mengxue Fei, Xinying Zhou, Yuejun Li & Dadi Jin
Pages: 1859-1866
Published online: 09 Aug 2019
AbstractforThe potential value of lncRNA-BC050642 in osteosarcoma origination and outcomes | Full Text | References | PDF (960.7 KB) | EPUB
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Article
Effect of electrical stimulation combined with graphene-oxide-based membranes on neural stem cell proliferation and differentiation
Chuan Fu, Su Pan, Yue Ma, Weijian Kong, Zhiping Qi & Xiaoyu Yang
Pages: 1867-1876
Published online: 10 May 2019
AbstractforEffect of electrical stimulation combined with graphene-oxide-based membranes on neural stem cell proliferation and differentiation | Full Text | References | PDF (1.5 MB) | EPUB
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Article
Emodin weakens liver inflammatory injury triggered by lipopolysaccharide through elevating microRNA-145 in vitro and in vivo
RuiJin Xie, Mei Liu & ShuJie Li
Pages: 1877-1887
Published online: 11 May 2019
AbstractforEmodin weakens liver inflammatory injury triggered by lipopolysaccharide through elevating microRNA-145 in vitro and in vivo | Full Text | References | PDF (1.4 MB) | EPUB
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Improved flowing behaviour and gas exchange of stored red blood cells by a compound porous structure
Jing Liu, Yusu Han, Wenda Hua, Ying Wang, Guoxing You, Penglong Li, Fulong Liao, Lian Zhao & Yongsheng Ding
Pages: 1888-1897
Published online: 10 May 2019
AbstractforImproved flowing behaviour and gas exchange of stored red blood cells by a compound porous structure | Full Text | References | PDF (1.4 MB) | EPUB
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Biomimetic hydroxyapatite/poly xylitol sebacic adibate/vitamin K nanocomposite for enhancing bone regeneration
Zhipeng Dai, Minyan Dang, Wenzhi Zhang, Sumathra Murugan, Seoh Wei Teh & Haiyan Pan
Pages: 1898-1907
Published online: 08 May 2019
AbstractforBiomimetic hydroxyapatite/poly xylitol sebacic adibate/vitamin K nanocomposite for enhancing bone regeneration | Full Text | References | PDF (1.7 MB) | EPUB
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Article
Identification of novel blood-based HCC-specific diagnostic biomarkers for human hepatocellular carcinoma
Li Yin, Na He, Chuizhe Chen, Nan Zhang, Yingzi Lin & Qianfeng Xia
Pages: 1908-1916
Published online: 10 May 2019
AbstractforIdentification of novel blood-based HCC-specific diagnostic biomarkers for human hepatocellular carcinoma | Full Text | References | PDF (1.7 MB) | EPUB
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Effects of Srxn1 on growth and Notch signalling of astrocyte induced by hydrogen peroxide
Lan Li, Guangjun Lin, Huizi Gu, Lei Yu & Changwei Ni
Pages: 1917-1923
Published online: 13 May 2019
AbstractforEffects of Srxn1 on growth and Notch signalling of astrocyte induced by hydrogen peroxide | Full Text | References | PDF (965 KB) | EPUB
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Article
Clinical characteristics and potential indicators for definite diagnosis of tuberculous pleural effusion
Xuemei Yang, Mingxia Feng, Ye Shen, Bo Deng, Yong He & Guoqiang Cao
Pages: 1924-1931
Published online: 16 May 2019
AbstractforClinical characteristics and potential indicators for definite diagnosis of tuberculous pleural effusion | Full Text | References | PDF (729.1 KB) | EPUB
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Article
Study of As2O3 regulating proliferation and apoptosis of Tca8113 cells by inhibiting the expression of Id-1
Yanfeng Zhu, Weihui Chen, Weiqun Guan, Yihong Fang & Chunfeng Hao
Pages: 1932-1937
Published online: 13 May 2019
AbstractforStudy of As2O3 regulating proliferation and apoptosis of Tca8113 cells by inhibiting the expression of Id-1 | Full Text | References | PDF (787.9 KB) | EPUB
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Article
Photosynthesized gold nanoparticles from Catharanthus roseus induces caspase-mediated apoptosis in cervical cancer cells (HeLa)
Yang Ke, Mohammed Saleh Al Aboody, Wael Alturaiki, Suliman A. Alsagaby, Faiz Abdulaziz Alfaiz, Vishnu Priya Veeraraghavan & Suresh Mickymaray
Pages: 1938-1946
Published online: 17 May 2019
AbstractforPhotosynthesized gold nanoparticles from Catharanthus roseus induces caspase-mediated apoptosis in cervical cancer cells (HeLa) | Full Text | References | PDF (1.2 MB) | EPUB
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Development of R8 modified epirubicin–dihydroartemisinin liposomes for treatment of non-small-cell lung cancer
Jing-Jing Liu, Wei Tang, Min Fu, Xiao-Qing Gong, Liang Kong, Xue-Min Yao, Ming Jing, Fu-Yi Cai, Xue-Tao Li & Rui-Jun Ju
Pages: 1947-1960
Published online: 13 May 2019
AbstractforDevelopment of R8 modified epirubicin–dihydroartemisinin liposomes for treatment of non-small-cell lung cancer | Full Text | References | PDF (4 MB) | EPUB
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Alantolactone induces apoptosis through ROS-mediated AKT pathway and inhibition of PINK1-mediated mitophagy in human HepG2 cells
Xing Kang, Hijuan Wang, Yanwei Li, Ying Xiao, Lili Zhao, Tingting Zhang, Shaohe Zhou, Xiaolun Zhou, Yi Li, Zhexing Shou, Chao Chen & Bin Li
Pages: 1961-1970
Published online: 22 May 2019
AbstractforAlantolactone induces apoptosis through ROS-mediated AKT pathway and inhibition of PINK1-mediated mitophagy in human HepG2 cells | Full Text | References | PDF (1.5 MB) | EPUB
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Cyclin D1 regulates osteoarthritis chondrocyte apoptosis via WNT3/β-catenin signalling
Yi-Yue Chen, You Chen, Wan-Chuan Wang, Qi- Tang, Ren Wu, Wei-Hong Zhu, Ding Li & Le-Le Liao
Pages: 1971-1977
Published online: 03 Jun 2019
AbstractforCyclin D1 regulates osteoarthritis chondrocyte apoptosis via WNT3/β-catenin signalling | Full Text | References | PDF (997 KB) | EPUB
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Mechanism of miR-148b inhibiting cell proliferation and migration of Schwann cells by regulating CALR
Zhenyu Zhou, Ning Zhang, Peilei Shi & Jin Xie
Pages: 1978-1983
Published online: 07 Jun 2019
AbstractforMechanism of miR-148b inhibiting cell proliferation and migration of Schwann cells by regulating CALR | Full Text | References | PDF (917.6 KB) | EPUB
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Parathyroid hormone-related protein activates HSCs via hedgehog signalling during liver fibrosis development
Shuying He, Jing Tang, Na Diao, Yan Liao, Jie Shi, Xiaoping Xu, Fang Xie & Lan Bai
Pages: 1984-1994
Published online: 16 Jul 2019
AbstractforParathyroid hormone-related protein activates HSCs via hedgehog signalling during liver fibrosis development | Full Text | References | PDF (1.9 MB) | EPUB
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Vascular protection of salicin on IL-1β-induced endothelial inflammatory response and damages in retinal endothelial cells
Yu Song, Xia Tian, Xuehong Wang & Hui Feng
Pages: 1995-2002
Published online: 20 May 2019
AbstractforVascular protection of salicin on IL-1β-induced endothelial inflammatory response and damages in retinal endothelial cells | Full Text | References | PDF (998.2 KB) | EPUB
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Orexin A ameliorates HBV X protein-induced cytotoxicity and inflammatory response in human hepatocytes
Li Wang, Tao He, Baishun Wan, Xiaoqian Wang & Ling Zhang
Pages: 2003-2009
Published online: 20 May 2019
AbstractforOrexin A ameliorates HBV X protein-induced cytotoxicity and inflammatory response in human hepatocytes | Full Text | References | PDF (874.5 KB) | EPUB
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Article
Quercetin protect cigarette smoke extracts induced inflammation and apoptosis in RPE cells
Qi Zhu, Mingxi Liu, Yuxi He & Bo Yang
Pages: 2010-2015
Published online: 23 May 2019
AbstractforQuercetin protect cigarette smoke extracts induced inflammation and apoptosis in RPE cells | Full Text | References | PDF (712.9 KB) | EPUB
  • 2925 Views
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Article
6-Gingerol protects cardiocytes H9c2 against hypoxia-induced injury by suppressing BNIP3 expression
Qi Ren, Shaojun Zhao & Changjie Ren
Pages: 2016-2023
Published online: 21 Jun 2019
Abstractfor6-Gingerol protects cardiocytes H9c2 against hypoxia-induced injury by suppressing BNIP3 expression | Full Text | References | PDF (1.1 MB) | EPUB
  • 2481 Views
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Article
Synthesis, identification and application of the novel metal-organic framework Fe3O4@PAA@ZIF-8 for the drug delivery of ciprofloxacin and investigation of antibacterial activity
Maryam Esfahanian, Mohammad Ali Ghasemzadeh & Seyyed Mohammad Hossein Razavian
Pages: 2024-2030
Published online: 21 May 2019
AbstractforSynthesis, identification and application of the novel metal-organic framework Fe3O4@PAA@ZIF-8 for the drug delivery of ciprofloxacin and investigation of antibacterial activity | Full Text | References | PDF (1.1 MB) | EPUB
  • 6426 Views
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Review

Review
DNA methylation abnormalities in atherosclerosis
Samira Tabaei & Seyyedeh Samaneh Tabaee
Pages: 2031-2041
Published online: 22 May 2019
AbstractforDNA methylation abnormalities in atherosclerosis | Full Text | References | PDF (1.1 MB) | EPUB
  • 9464 Views
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Research Article

Article
MiR-34b regulates cervical cancer cell proliferation and apoptosis
Zhen Cao, Gong Zhang, Conghua Xie & Yunfeng Zhou
Pages: 2042-2047
Published online: 23 May 2019
AbstractforMiR-34b regulates cervical cancer cell proliferation and apoptosis | Full Text | References | PDF (735.2 KB) | EPUB
  • 2318 Views
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Article
RETRACTED ARTICLE: K-RasG12V/Y40C-PI3K/AKT pathway regulates H1.4S35ph through PKA to promote the occurrence and development of osteosarcoma cancer
Jingzhe Zhang, Wanguo Liu, Hang Dong & Wenjun Wang
Pages: 2048-2057
Published online: 24 May 2019
AbstractforRETRACTED ARTICLE: K-RasG12V/Y40C-PI3K/AKT pathway regulates H1.4S35ph through PKA to promote the occurrence and development of osteosarcoma cancer | PDF (2.6 MB)
  • 1342 Views
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Research Article

Article
MiR-193b inhibits the growth and metastasis of renal cell carcinoma by targeting IGF1R
Jianhui Chen, Ting Deng, Xiaofan Li & Weizhong Cai
Pages: 2058-2064
Published online: 24 May 2019
AbstractforMiR-193b inhibits the growth and metastasis of renal cell carcinoma by targeting IGF1R | Full Text | References | PDF (906.1 KB) | EPUB
  • 2223 Views
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Article
Mechanism of miR-143-3p inhibiting proliferation, migration and invasion of osteosarcoma cells by targeting MAPK7
Yu Hou, Helin Feng, Jianbao Jiao, Ligang Qian, Bo Sun, Pingtao Chen, Qinggui Li & Zhixing Liang
Pages: 2065-2071
Published online: 24 May 2019
AbstractforMechanism of miR-143-3p inhibiting proliferation, migration and invasion of osteosarcoma cells by targeting MAPK7 | Full Text | References | PDF (945.3 KB) | EPUB
  • 1768 Views
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Article
Isolation and characterization of a novel thermophile; Bacillus haynesii, applied for the green synthesis of ZnO nanoparticles
Suriya Rehman, B. Rabindran Jermy, Sultan Akhtar, J. Francis Borgio, Sayed Abdul Azeez, Vijaya Ravinayagam, Reem Al Jindan, Zainab Hassan Alsalem, Abdullah Buhameid & Adil Gani
Pages: 2072-2082
Published online: 24 May 2019
AbstractforIsolation and characterization of a novel thermophile; Bacillus haynesii, applied for the green synthesis of ZnO nanoparticles | Full Text | References | PDF (1.8 MB) | EPUB
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Article
RETRACTED ARTICLE: Upregulation of long non-coding RNA OGFRP1 facilitates endometrial cancer through regulating miR-124-3p/SIRT1 axis and activating PI3K/AKT/GSK-3β pathway
Yuqiong Lv, Shaorong Chen, Jingjing Wu, Ruyin Lin, Limei Zhou, Guimin Chen, Huiqing Chen & Yumin Ke
Pages: 2083-2090
Published online: 26 May 2019
AbstractforRETRACTED ARTICLE: Upregulation of long non-coding RNA OGFRP1 facilitates endometrial cancer through regulating miR-124-3p/SIRT1 axis and activating PI3K/AKT/GSK-3β pathway | PDF (2.6 MB)
  • 1490 Views
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Research Article

Article
The long noncoding RNA linc00858 promotes progress of lung cancer through miR-3182/MMP2 axis
Mingqiang Xue, Dongfeng Shi, Guanghui Xu & Wenguang Wang
Pages: 2091-2097
Published online: 26 May 2019
AbstractforThe long noncoding RNA linc00858 promotes progress of lung cancer through miR-3182/MMP2 axis | Full Text | References | PDF (1 MB) | EPUB
  • 1700 Views
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Article
Abnormal expression of long noncoding RNA FGD5-AS1 affects the development of periodontitis through regulating miR-142-3p/SOCS6/NF-κB pathway
Hong Chen, Zedong Lan, Qiaomei Li & Yuehong Li
Pages: 2098-2106
Published online: 30 May 2019
AbstractforAbnormal expression of long noncoding RNA FGD5-AS1 affects the development of periodontitis through regulating miR-142-3p/SOCS6/NF-κB pathway | Full Text | References | PDF (1.4 MB) | EPUB
  • 2593 Views
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Article
Silver/silver chloride (Ag/AgCl) nanoparticles synthesized from Azadirachta indica lalex and its antibiofilm activity against fluconazole resistant Candida tropicalis
Mohammed Saleh Al Aboody
Pages: 2107-2113
Published online: 29 May 2019
AbstractforSilver/silver chloride (Ag/AgCl) nanoparticles synthesized from Azadirachta indica lalex and its antibiofilm activity against fluconazole resistant Candida tropicalis | Full Text | References | PDF (957.2 KB) | EPUB
  • 4158 Views
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Article
Integrated bioinformatics analysis of miRNA expression in Ewing sarcoma and potential regulatory effects of miR-21 via targeting ALCAM/CD166
Yuzhe Liu, Gaoyang Chen, He Liu, Zhaoyan Li, Qiwei Yang, Xinming Gu, Zhenwu Du, Guizhen Zhang & Jincheng Wang
Pages: 2114-2122
Published online: 29 May 2019
AbstractforIntegrated bioinformatics analysis of miRNA expression in Ewing sarcoma and potential regulatory effects of miR-21 via targeting ALCAM/CD166 | Full Text | References | PDF (1.4 MB) | EPUB
  • 2814 Views
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Article
Oral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation
Masoumeh Kurd, Soroor Sadegh Malvajerd, Saeed Rezaee, Mehrdad Hamidi & Katayoun Derakhshandeh
Pages: 2123-2133
Published online: 03 Jun 2019
AbstractforOral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation | Full Text | References | PDF (1.6 MB) | EPUB
  • 2602 Views
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Article
RETRACTED ARTICLE: Association between nucleotide-binding oligomerization domain protein 2 (NOD2) gene polymorphisms and Parkinson’s disease (PD) susceptibility
Meiling Xu, Shuangyan Zhang, Hong Zhao, Chi Ma & Yujun Pan
Pages: 2134-2138
Published online: 30 May 2019
AbstractforRETRACTED ARTICLE: Association between nucleotide-binding oligomerization domain protein 2 (NOD2) gene polymorphisms and Parkinson’s disease (PD) susceptibility | PDF (1.3 MB)
  • 1098 Views
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Research Article

Article
Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes
Qianjun Wang, Xiaomei Xu, Zhiqiang Kang, Zhentao Zhang & Yanmin Li
Pages: 2139-2145
Published online: 30 May 2019
AbstractforPaeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes | Full Text | References | PDF (1.1 MB) | EPUB
  • 2680 Views
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Article
Ameliorative effect of synthesized silver nanoparticles by green route method from Zingiber zerumbet on mycoplasmal pneumonia in experimental mice
Yong Yang, Wenping Song, Zongbo Chen, Qiubo Li & Li Liu
Pages: 2146-2154
Published online: 04 Jun 2019
AbstractforAmeliorative effect of synthesized silver nanoparticles by green route method from Zingiber zerumbet on mycoplasmal pneumonia in experimental mice | Full Text | References | PDF (1.1 MB) | EPUB
  • 3138 Views
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Article
The diagnostic performance of lysine(K)-specific demethylase 6B (KDM6B) in non-small cell lung cancer
Ting Ge, Ying Zhou & Hongmin Lu
Pages: 2155-2160
Published online: 03 Jun 2019
AbstractforThe diagnostic performance of lysine(K)-specific demethylase 6B (KDM6B) in non-small cell lung cancer | Full Text | References | PDF (695.6 KB) | EPUB
  • 1733 Views
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Article
Investigating the effect of near infrared photo thermal therapy folic acid conjugated gold nano shell on melanoma cancer cell line A375
Fateme Sadat Majidi, Elham Mohammadi, Bita Mehravi, Samira Nouri, Khadije Ashtari & Ali Neshasteh-riz
Pages: 2161-2170
Published online: 03 Jun 2019
AbstractforInvestigating the effect of near infrared photo thermal therapy folic acid conjugated gold nano shell on melanoma cancer cell line A375 | Full Text | References | PDF (1.3 MB) | EPUB
  • 3303 Views
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Article
Rabdosia rubescens Linn: green synthesis of gold nanoparticles and their anticancer effects against human lung cancer cells A549
Xi Zhang, Zhenyue Tan, Kunjing Jia, Wenzhi Zhang & Minyan Dang
Pages: 2171-2178
Published online: 04 Jun 2019
AbstractforRabdosia rubescens Linn: green synthesis of gold nanoparticles and their anticancer effects against human lung cancer cells A549 | Full Text | References | PDF (1 MB) | EPUB
  • 3418 Views
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Article
Pretreatment of ghrelin protects H9c2 cells against hypoxia/reoxygenation-induced cell death via PI3K/AKT and AMPK pathways
Yanbo Chen, Honggang Wang, Yong Zhang, Zhengping Wang, Shanshan Liu & Lianqun Cui
Pages: 2179-2187
Published online: 04 Jun 2019
AbstractforPretreatment of ghrelin protects H9c2 cells against hypoxia/reoxygenation-induced cell death via PI3K/AKT and AMPK pathways | Full Text | References | PDF (1.3 MB) | EPUB
  • 2786 Views
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Article
RETRACTED ARTICLE: Astragalus polysaccharide alleviates H2O2-triggered oxidative injury in human umbilical vein endothelial cells via promoting KLF2
Dongtao Li, Yan Liu, Rong Xu, Xin Jia, Xing Li, Cong Huo & Xiaoming Wang
Pages: 2188-2195
Published online: 04 Jun 2019
AbstractforRETRACTED ARTICLE: Astragalus polysaccharide alleviates H2O2-triggered oxidative injury in human umbilical vein endothelial cells via promoting KLF2 | PDF (2.8 MB)
  • 1588 Views
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Research Article

Article
Platforms for delivery of macromolecules to sites of DNA double-strand break repair
Zhen Cao, Deepika Goyal, Steffen E. Meiler, Yunfeng Zhou & William S. Dynan
Pages: 2196-2204
Published online: 04 Jun 2019
AbstractforPlatforms for delivery of macromolecules to sites of DNA double-strand break repair | Full Text | References | PDF (1.3 MB) | EPUB
  • 1654 Views
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Article
RETRACTED ARTICLE: Silence of lncRNA GAS5 alleviates high glucose toxicity to human renal tubular epithelial HK-2 cells through regulation of miR-27a
Lina Lv, Dandan Li, Fengqun Tian, Xia Li, Jing Zhang & Xiulian Yu
Pages: 2205-2212
Published online: 03 Jun 2019
AbstractforRETRACTED ARTICLE: Silence of lncRNA GAS5 alleviates high glucose toxicity to human renal tubular epithelial HK-2 cells through regulation of miR-27a | PDF (2.1 MB)
  • 2031 Views
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Research Article

Article
Anagliptin protects neuronal cells against endogenous amyloid β (Aβ)-induced cytotoxicity and apoptosis
Zhenbo Chen, Shanwei Tao, Xiaohui Li, Xudong Zeng, Mirong Zhang & Qinghe Yao
Pages: 2213-2220
Published online: 03 Jun 2019
AbstractforAnagliptin protects neuronal cells against endogenous amyloid β (Aβ)-induced cytotoxicity and apoptosis | Full Text | References | PDF (1 MB) | EPUB
  • 2481 Views
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Article
Long non-coding RNA ROR mitigates cobalt chloride-induced hypoxia injury through regulation of miR-145
Hai Ge, Jing Liu, Fengxian Liu, Yanan Sun & Rong Yang
Pages: 2221-2229
Published online: 05 Jun 2019
AbstractforLong non-coding RNA ROR mitigates cobalt chloride-induced hypoxia injury through regulation of miR-145 | Full Text | References | PDF (1.1 MB) | EPUB
  • 2222 Views
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Article
Biosynthesis and characterization of magnesium oxide and manganese dioxide nanoparticles using Matricaria chamomilla L. extract and its inhibitory effect on Acidovorax oryzae strain RS-2
Solabomi Olaitan Ogunyemi, Feng Zhang, Yasmine Abdallah, Muchen Zhang, Yanli Wang, Guochang Sun, Wen Qiu & Bin Li
Pages: 2230-2239
Published online: 04 Jun 2019
AbstractforBiosynthesis and characterization of magnesium oxide and manganese dioxide nanoparticles using Matricaria chamomilla L. extract and its inhibitory effect on Acidovorax oryzae strain RS-2 | Full Text | References | PDF (1.6 MB) | EPUB
  • 8062 Views
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Correction

Correction
Correction
Page: 2240
Published online: 07 Jun 2019
CitationforCorrection | Full Text | PDF (208.7 KB) | EPUB
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Article
RETRACTED ARTICLE: The value of FGF9 as a novel biomarker in the diagnosis of prostate cancer
Genggang Cui, Mingming Shao, Xingzhou Gu, Hongbo Guo, Shiqing Zhang, Jianlei Lu & Hongbin Ma
Pages: 2241-2245
Published online: 07 Jun 2019
AbstractforRETRACTED ARTICLE: The value of FGF9 as a novel biomarker in the diagnosis of prostate cancer | PDF (1.4 MB)
  • 1370 Views
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Research Article

Article
A novel prognostic score model based on combining systemic and hepatic inflammation markers in the prognosis of HBV-associated hepatocellular carcinoma patients
Tingting Zhang, Zhe Liu, Xiangqian Zhao, Zhiyuan Mao & Li Bai
Pages: 2246-2255
Published online: 06 Jun 2019
AbstractforA novel prognostic score model based on combining systemic and hepatic inflammation markers in the prognosis of HBV-associated hepatocellular carcinoma patients | Full Text | References | PDF (961.7 KB) | EPUB
  • 2418 Views
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Article
Swainsonine inhibits proliferation and collagen synthesis of NIH-3T3 cells by declining miR-21
Chao Li, Peipei Wang, Ziyang Fu, Yongtao Li & Shouju Li
Pages: 2256-2264
Published online: 11 Jun 2019
AbstractforSwainsonine inhibits proliferation and collagen synthesis of NIH-3T3 cells by declining miR-21 | Full Text | References | PDF (1.2 MB) | EPUB
  • 2515 Views
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Article
RETRACTED ARTICLE: Silence of lncRNA ANRIL represses cell growth and promotes apoptosis in retinoblastoma cells through regulating miR-99a and c-Myc
Xiaomin Wang, Xinxia Zhang, Yutong Han, Qiuli Wang, Yanfan Ren, Baojun Wang & Junxi Hu
Pages: 2265-2273
Published online: 11 Jun 2019
AbstractforRETRACTED ARTICLE: Silence of lncRNA ANRIL represses cell growth and promotes apoptosis in retinoblastoma cells through regulating miR-99a and c-Myc | PDF (2.6 MB)
  • 1540 Views
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Research Article

Article
Cardio-protective effects of salvianolic acid B on oxygen and glucose deprivation (OGD)-treated H9c2 cells
Bin Yang, Chunyan Zheng, Haichu Yu, Rui Zhang, Cong Zhao & Shanglang Cai
Pages: 2274-2281
Published online: 11 Jun 2019
AbstractforCardio-protective effects of salvianolic acid B on oxygen and glucose deprivation (OGD)-treated H9c2 cells | Full Text | References | PDF (1,004.7 KB) | EPUB
  • 2334 Views
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Article
The 100 top-cited studies in cancer immunotherapy
Yonggang Zhang, Liuliu Quan & Liang Du
Pages: 2282-2292
Published online: 06 Jun 2019
AbstractforThe 100 top-cited studies in cancer immunotherapy | Full Text | References | PDF (904.4 KB) | EPUB
  • 5936 Views
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Article
RETRACTED ARTICLE: Formaldehyde inhibits proliferation of bronchial epithelial cells by down-regulating miR-375
Lei Yu & ChunWen Li
Pages: 2293-2297
Published online: 07 Jun 2019
AbstractforRETRACTED ARTICLE: Formaldehyde inhibits proliferation of bronchial epithelial cells by down-regulating miR-375 | PDF (1.5 MB)
  • 1150 Views
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Research Article

Article
Cancer cell membrane coated silica nanoparticles loaded with ICG for tumour specific photothermal therapy of osteosarcoma
Jingwei Zhang, Yu Miao, Weifeng Ni, Haijun Xiao & Jieyuan Zhang
Pages: 2298-2305
Published online: 07 Jun 2019
AbstractforCancer cell membrane coated silica nanoparticles loaded with ICG for tumour specific photothermal therapy of osteosarcoma | Full Text | References | PDF (1.1 MB) | EPUB
  • 3892 Views
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Correction

Correction
Correction
Page: 2306
Published online: 14 Jun 2019
CitationforCorrection | Full Text | PDF (153.2 KB) | EPUB
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Article
RETRACTED ARTICLE: The pivotal role and mechanism of long non-coding RNA B3GALT5-AS1 in the diagnosis of acute pancreatitis
Linlin Wang, Xiaonan Zhao & Ye Wang
Pages: 2307-2315
Published online: 08 Jun 2019
AbstractforRETRACTED ARTICLE: The pivotal role and mechanism of long non-coding RNA B3GALT5-AS1 in the diagnosis of acute pancreatitis | PDF (2.6 MB)
  • 1821 Views
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Research Article

Article
NIR triggered glycosylated gold nanoshell as a photothermal agent on melanoma cancer cells
Samira Nouri, Elham Mohammadi, Bita Mehravi, Fatemehsadat Majidi, Khadijeh Ashtari, Ali Neshasteh-Riz & Samira Einali
Pages: 2316-2324
Published online: 11 Jun 2019
AbstractforNIR triggered glycosylated gold nanoshell as a photothermal agent on melanoma cancer cells | Full Text | References | PDF (1.2 MB) | EPUB
  • 2375 Views
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Retracted Article

Article
RETRACTED ARTICLE: GLP-1 receptor agonist lixisenatide protects against high free fatty acids-induced oxidative stress and inflammatory response
Qini Zhao, Haiming Xu, Lirong Zhang, Long Liu & Libo Wang
Pages: 2325-2332
Published online: 07 Jun 2019
AbstractforRETRACTED ARTICLE: GLP-1 receptor agonist lixisenatide protects against high free fatty acids-induced oxidative stress and inflammatory response | PDF (2 MB)
  • 1783 Views
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Research Article

Article
Interactive effects of AURKA polymorphisms with smoking on the susceptibility of oral cancer
Chao Huang, Lili Wang, Hongguang Song & Cungang Wu
Pages: 2333-2337
Published online: 07 Jun 2019
AbstractforInteractive effects of AURKA polymorphisms with smoking on the susceptibility of oral cancer | Full Text | References | PDF (531.5 KB) | EPUB
  • 1662 Views
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Article
Association between EPHX1 polymorphism rs1051740 and the risk of ovarian cancer: a meta-analysis
Ying Jin
Pages: 2338-2342
Published online: 07 Jun 2019
AbstractforAssociation between EPHX1 polymorphism rs1051740 and the risk of ovarian cancer: a meta-analysis | Full Text | References | PDF (591.9 KB) | EPUB
  • 2002 Views
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Article
RETRACTED ARTICLE: Ras-ERK signalling represses H1.4 phosphorylation at serine 36 to promote non-small-cell lung carcinoma cells growth and migration
Shaomin Shi, Jingzhe Zhang, Meihan Liu, Hang Dong & Ning Li
Pages: 2343-2351
Published online: 11 Jun 2019
AbstractforRETRACTED ARTICLE: Ras-ERK signalling represses H1.4 phosphorylation at serine 36 to promote non-small-cell lung carcinoma cells growth and migration | PDF (2.6 MB)
  • 1463 Views
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Research Article

Article
LINC00305 represses miR-124 expression to trigger inflammatory insults in the presence of lipopolysaccharide
Xiaoyan Li, Manqiu Yu, Liang Han, Lei Chen, Daxue Zhang, Guannan Zhou, Qiang Zhao & Taitao Sun
Pages: 2352-2360
Published online: 13 Jun 2019
AbstractforLINC00305 represses miR-124 expression to trigger inflammatory insults in the presence of lipopolysaccharide | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Bioconjugation as a smart immobilization approach for α-amylase enzyme using stimuli-responsive Eudragit-L100 polymer: a robust biocatalyst for applications in pharmaceutical industry
Heidi Mohamed Abdel-Mageed, Rasha Ali Radwan, Nermeen Zakaria AbuelEzz, Hebatallah Ahmed Nasser, Aliaa Ali El Shamy, Rana M. Abdelnaby & Nesrine Abdelrehim EL Gohary
Pages: 2361-2368
Published online: 13 Jun 2019
AbstractforBioconjugation as a smart immobilization approach for α-amylase enzyme using stimuli-responsive Eudragit-L100 polymer: a robust biocatalyst for applications in pharmaceutical industry | Full Text | References | PDF (855.5 KB) | EPUB
  • 3088 Views
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Article
Silence of MEG3 intensifies lipopolysaccharide-stimulated damage of human lung cells through modulating miR-4262
Xiaoliang Li, Qianqian Zhang & Zhigang Yang
Pages: 2369-2378
Published online: 11 Jun 2019
AbstractforSilence of MEG3 intensifies lipopolysaccharide-stimulated damage of human lung cells through modulating miR-4262 | Full Text | References | PDF (1.4 MB) | EPUB
  • 2323 Views
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Article
RETRACTED ARTICLE: Notoginsenoside R1 alleviates TNF-α-induced pancreatic β-cell Min6 apoptosis and dysfunction through up-regulation of miR-29a
Xiabo Chen, Renxiong Wei, Tinglong Jin & Hanguang Du
Pages: 2379-2388
Published online: 11 Jun 2019
AbstractforRETRACTED ARTICLE: Notoginsenoside R1 alleviates TNF-α-induced pancreatic β-cell Min6 apoptosis and dysfunction through up-regulation of miR-29a | PDF (3.4 MB)
  • 1673 Views
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Correction

Correction
Correction
Page: 2389
Published online: 17 Jun 2019
CitationforCorrection | Full Text | PDF (563.3 KB) | EPUB
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Correction
Correction
Page: 2390
Published online: 17 Jun 2019
CitationforCorrection | Full Text | PDF (236.3 KB) | EPUB
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Article
RETRACTED ARTICLE: Degradable poly-L-lysine-modified PLGA cell microcarriers with excellent antibacterial and osteogenic activity
Hanyang Zhang, Jianhang Jiao & Hui Jin
Pages: 2391-2404
Published online: 11 Jun 2019
AbstractforRETRACTED ARTICLE: Degradable poly-L-lysine-modified PLGA cell microcarriers with excellent antibacterial and osteogenic activity | PDF (3.4 MB)
  • 2277 Views
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Research Article

Article
Ultrasound assisted-phytofabricated Fe3O4 NPs with antioxidant properties and antibacterial effects on growth, biofilm formation, and spreading ability of multidrug resistant bacteria
Mehran Alavi & Naser Karimi
Pages: 2405-2423
Published online: 12 Jun 2019
AbstractforUltrasound assisted-phytofabricated Fe3O4 NPs with antioxidant properties and antibacterial effects on growth, biofilm formation, and spreading ability of multidrug resistant bacteria | Full Text | References | PDF (3.1 MB) | EPUB
  • 2848 Views
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Article
Biological mediated Ag nanoparticles from Barleria longiflora for antimicrobial activity and photocatalytic degradation using methylene blue
Vetrivel Cittrarasu, Balamuralikrishnan Balasubramanian, Durairaj Kaliannan, Sungkwon Park, Viji Maluventhan, Tanushri Kaul, Wen Chao Liu & Maruthupandian Arumugam
Pages: 2424-2430
Published online: 12 Jun 2019
AbstractforBiological mediated Ag nanoparticles from Barleria longiflora for antimicrobial activity and photocatalytic degradation using methylene blue | Full Text | References | PDF (1.2 MB) | EPUB
  • 3686 Views
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Article
Overexpression of the long non-coding RNA Oprm1 alleviates apoptosis from cerebral ischemia-reperfusion injury through the Oprm1/miR-155/GATA3 axis
Hongyu Jing, Lingyun Liu, Ye Jia, Hanxin Yao & Fuzhe Ma
Pages: 2431-2439
Published online: 12 Jun 2019
AbstractforOverexpression of the long non-coding RNA Oprm1 alleviates apoptosis from cerebral ischemia-reperfusion injury through the Oprm1/miR-155/GATA3 axis | Full Text | References | PDF (1.2 MB) | EPUB
  • 2365 Views
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Article
VHPKQHR peptide modified magnetic mesoporous nanoparticles for MRI detection of atherosclerosis lesions
Wan Xu, Shuihua Zhang, Quan Zhou & Wenli Chen
Pages: 2440-2448
Published online: 13 Jun 2019
AbstractforVHPKQHR peptide modified magnetic mesoporous nanoparticles for MRI detection of atherosclerosis lesions | Full Text | References | PDF (1.4 MB) | EPUB
  • 2788 Views
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Article
Hsa_Circ_0001206 is downregulated and inhibits cell proliferation, migration and invasion in prostate cancer
Zhenyu Song, Zhiyuan Zhuo, Zhe Ma, Chuansheng Hou, Gang Chen & Guoxiong Xu
Pages: 2449-2464
Published online: 14 Jun 2019
AbstractforHsa_Circ_0001206 is downregulated and inhibits cell proliferation, migration and invasion in prostate cancer | Full Text | References | PDF (3.3 MB) | EPUB
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Article
Synergistic effect of silver nanoparticles and polymyxin B against biofilm produced by Pseudomonas aeruginosa isolates of pus samples in vitro
Muhammad Salman, Rizwana Rizwana, Hayat Khan, Iqbal Munir, Muhammad Hamayun, Aquib Iqbal, Abdul Rehman, Khalid Amin, Ghayour Ahmed, Majid Khan, Ajmal Khan & Faiz Ul Amin
Pages: 2465-2472
Published online: 12 Jun 2019
AbstractforSynergistic effect of silver nanoparticles and polymyxin B against biofilm produced by Pseudomonas aeruginosa isolates of pus samples in vitro | Full Text | References | PDF (1.2 MB) | EPUB
  • 3379 Views
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Article
RETRACTED ARTICLE: Mirt2 functions in synergy with miR-377 to participate in inflammatory pathophysiology of Sjögren's syndrome
Miaomiao Xin, Hongda Liang, Hongyue Wang, Dawei Wen, Liqin Wang, Lei Zhao, Mingshu Sun & Jibo Wang
Pages: 2473-2480
Published online: 14 Jun 2019
AbstractforRETRACTED ARTICLE: Mirt2 functions in synergy with miR-377 to participate in inflammatory pathophysiology of Sjögren's syndrome | PDF (2 MB)
  • 2210 Views
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Article
Delivery of mesenchymal stem cells-derived extracellular vesicles with enriched miR-185 inhibits progression of OPMD
Lin Wang, Panpan Yin, Jiaqi Wang, Yuanyuan Wang, Zheng Sun, Yu Zhou & Xiaobing Guan
Pages: 2481-2491
Published online: 20 Jun 2019
AbstractforDelivery of mesenchymal stem cells-derived extracellular vesicles with enriched miR-185 inhibits progression of OPMD | Full Text | References | PDF (1.8 MB) | EPUB
  • 3772 Views
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Article
Angelica polysaccharide moderates hypoxia-evoked apoptosis and autophagy in rat neural stem cells by downregulation of BNIP3
Yongzhen Xue, Dongmei Li, Yige Zhang, Hang Gao & Hui Li
Pages: 2492-2499
Published online: 17 Jun 2019
AbstractforAngelica polysaccharide moderates hypoxia-evoked apoptosis and autophagy in rat neural stem cells by downregulation of BNIP3 | Full Text | References | PDF (1,017.3 KB) | EPUB
  • 2050 Views
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Article
Angiotensin I-converting enzyme gene plays a crucial role in the pathology of carcinomas in colorectal cancer
Keqian Zhang, Tianqi Mao, Zhicheng He, Xiaojiao Wu, Yu Peng, Yanrong Chen, Yan Dong, Zhihua Ruan & Zhe Wang
Pages: 2500-2506
Published online: 17 Jun 2019
AbstractforAngiotensin I-converting enzyme gene plays a crucial role in the pathology of carcinomas in colorectal cancer | Full Text | References | PDF (817.6 KB) | EPUB
  • 1496 Views
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Article
Knockdown of lncRNA LSINCT5 suppresses growth and metastasis of human glioma cells via up-regulating miR-451
Bin Liu, Wei Cao & Hui Ma
Pages: 2507-2515
Published online: 18 Jun 2019
AbstractforKnockdown of lncRNA LSINCT5 suppresses growth and metastasis of human glioma cells via up-regulating miR-451 | Full Text | References | PDF (1.4 MB) | EPUB
  • 1852 Views
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Article
Long non-coding RNA NEAT1 can predict various malignant tumour lympha node metastasis: a meta-analysis
Lei Zhang, Zhe Zhang & Zhenglun Yu
Pages: 2516-2520
Published online: 18 Jun 2019
AbstractforLong non-coding RNA NEAT1 can predict various malignant tumour lympha node metastasis: a meta-analysis | Full Text | References | PDF (640.3 KB) | EPUB
  • 1968 Views
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Article
Silence of lncRNA MIAT protects ATDC5 cells against lipopolysaccharides challenge via up-regulating miR-132
Chen Li, Su Pan, Yan Song, Yinqing Li & Ji Qu
Pages: 2521-2527
Published online: 17 Jun 2019
AbstractforSilence of lncRNA MIAT protects ATDC5 cells against lipopolysaccharides challenge via up-regulating miR-132 | Full Text | References | PDF (1.1 MB) | EPUB
  • 2066 Views
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Correction

Correction
Correction
Page: 2528
Published online: 17 Jun 2019
CitationforCorrection | Full Text | PDF (227.8 KB) | EPUB
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Research Article

Article
Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2
Nan Li, XiaoRong Guo, Lei Liu, Lu Wang & Rongjie Cheng
Pages: 2529-2535
Published online: 17 Jun 2019
AbstractforMolecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2 | Full Text | References | PDF (913.1 KB) | EPUB
  • 2277 Views
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Retracted Article

Article
RETRACTED ARTICLE: Long noncoding RNA SNHG15 enhances the development of colorectal carcinoma via functioning as a ceRNA through miR-141/SIRT1/Wnt/β-catenin axis
Xiantao Sun, Yang Bai, Chao Yang, Shengyun Hu, Zhili Hou & Guixian Wang
Pages: 2536-2544
Published online: 18 Jun 2019
AbstractforRETRACTED ARTICLE: Long noncoding RNA SNHG15 enhances the development of colorectal carcinoma via functioning as a ceRNA through miR-141/SIRT1/Wnt/β-catenin axis | PDF (3.1 MB)
  • 2166 Views
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Article
RETRACTED ARTICLE: Tetramethylpyrazine relieves LPS-induced pancreatic β-cell Min6 injury via regulation of miR-101/MKP-1
Dong Chen, Dong Cao & Ping Sui
Pages: 2545-2552
Published online: 19 Jun 2019
AbstractforRETRACTED ARTICLE: Tetramethylpyrazine relieves LPS-induced pancreatic β-cell Min6 injury via regulation of miR-101/MKP-1 | PDF (2.2 MB)
  • 1948 Views
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Research Article

Article
Sustainable production of biomass and industrially important secondary metabolites in cell cultures of selfheal (Prunella vulgaris L.) elicited by silver and gold nanoparticles
Hina Fazal, Bilal Haider Abbasi, Nisar Ahmad, Mohammad Ali, Syed Shujait Ali, Abbas Khan & Dong-Qing Wei
Pages: 2553-2561
Published online: 18 Jun 2019
AbstractforSustainable production of biomass and industrially important secondary metabolites in cell cultures of selfheal (Prunella vulgaris L.) elicited by silver and gold nanoparticles | Full Text | References | PDF (1.3 MB) | EPUB
  • 2928 Views
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Article
Designing an immunosensor for detection of Brucella abortus based on coloured silica nanoparticles
Arash Shams, Bahareh Rahimian Zarif, Mojtaba Salouti, Reza Shapouri & Sako Mirzaii
Pages: 2562-2568
Published online: 18 Jun 2019
AbstractforDesigning an immunosensor for detection of Brucella abortus based on coloured silica nanoparticles | Full Text | References | PDF (832.7 KB) | EPUB
  • 2380 Views
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Article
CGRP accelerates the pathogenesis of neurological heterotopic ossification following spinal cord injury
Xiguang Sang, Zhiyong Wang, Ping Shi, Yonggang Li & Lin Cheng
Pages: 2569-2574
Published online: 20 Jun 2019
AbstractforCGRP accelerates the pathogenesis of neurological heterotopic ossification following spinal cord injury | Full Text | References | PDF (967.9 KB) | EPUB
  • 2195 Views
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Article
Vacuolar protein sorting 4B regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells through the Wnt-β-catenin signalling pathway
Yuhua Pan, Ting Lu, Ling Peng, Zhao Chen, Meiyi Li, Kaiying Zhang, Fu Xiong & Buling Wu
Pages: 2575-2584
Published online: 20 Jun 2019
AbstractforVacuolar protein sorting 4B regulates the proliferation and odontoblastic differentiation of human dental pulp stem cells through the Wnt-β-catenin signalling pathway | Full Text | References | PDF (2 MB) | EPUB
  • 2169 Views
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Article
Oridonin relieves hypoxia-evoked apoptosis and autophagy via modulating microRNA-214 in H9c2 cells
Licheng Gong, Haiming Xu, Xiuli Zhang, Tao Zhang, Jingwei Shi & Hong Chang
Pages: 2585-2592
Published online: 21 Jun 2019
AbstractforOridonin relieves hypoxia-evoked apoptosis and autophagy via modulating microRNA-214 in H9c2 cells | Full Text | References | PDF (963.1 KB) | EPUB
  • 2565 Views
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Article
Chitosan nano-structure loaded with recombinant E. coli O157:H7 antigens as a vaccine candidate can effectively increase immunization capacity
Jaleh Khanifar, Ali Hatef Salmanian, Reza Haji Hosseini, Jafar Amani & Rohoallah Kazemi
Pages: 2593-2604
Published online: 26 Jun 2019
AbstractforChitosan nano-structure loaded with recombinant E. coli O157:H7 antigens as a vaccine candidate can effectively increase immunization capacity | Full Text | References | PDF (1.7 MB) | EPUB
  • 2024 Views
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Article
Bordetella pertussis antigens encapsulated into N-trimethyl chitosan nanoparticulate systems as a novel intranasal pertussis vaccine
Hamid Najminejad, Seyed Mehdi Kalantar, Ali Rezaei Mokarram, Mehran Dabaghian, Meghdad Abdollahpour-Alitappeh, Seyyed Mahmoud Ebrahimi, Majid Tebianian, Mahdi Fasihi Ramandi & Mohammad Hasan Sheikhha
Pages: 2605-2611
Published online: 26 Jun 2019
AbstractforBordetella pertussis antigens encapsulated into N-trimethyl chitosan nanoparticulate systems as a novel intranasal pertussis vaccine | Full Text | References | PDF (802.5 KB) | EPUB
  • 2540 Views
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Retracted Article

Article
RETRACTED ARTICLE: GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence
Huading Lu, Dawei Wang, Huizi Li, Junlong Zhong, Yimin Lin, Xianghe Xu & Bin Wang
Pages: 2612-2617
Published online: 25 Jun 2019
AbstractforRETRACTED ARTICLE: GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence | PDF (1.7 MB)
  • 2004 Views
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Research Article

Article
Salicin prevents TNF-α-induced cellular senescence in human umbilical vein endothelial cells (HUVECs)
Fei Guo, Rong Wu & Jian Xu
Pages: 2618-2623
Published online: 20 Jun 2019
AbstractforSalicin prevents TNF-α-induced cellular senescence in human umbilical vein endothelial cells (HUVECs) | Full Text | References | PDF (908.5 KB) | EPUB
  • 3045 Views
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Retracted Article

Article
RETRACTED ARTICLE: Overexpression of lncRNA ANRIL aggravated hydrogen peroxide-disposed injury in PC-12 cells via inhibiting miR-499a/PDCD4 axis-mediated PI3K/Akt/mTOR/p70S6K pathway
Zhiliang Guo, Lanlan Li, Yu Gao, Xiaoyun Zhang & Min Cheng
Pages: 2624-2633
Published online: 20 Jun 2019
AbstractforRETRACTED ARTICLE: Overexpression of lncRNA ANRIL aggravated hydrogen peroxide-disposed injury in PC-12 cells via inhibiting miR-499a/PDCD4 axis-mediated PI3K/Akt/mTOR/p70S6K pathway | PDF (3.6 MB)
  • 1605 Views
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Research Article

Article
A new method for early detection of pancreatic cancer biomarkers: detection of microRNAs by nanochannels
Jiasheng Xu, Kaili Liao, Zhonghua Fu & Zhenfang Xiong
Pages: 2634-2640
Published online: 20 Jun 2019
AbstractforA new method for early detection of pancreatic cancer biomarkers: detection of microRNAs by nanochannels | Full Text | References | PDF (998.1 KB) | EPUB
  • 3279 Views
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Article
FAK mediates BMP9-induced osteogenic differentiation via Wnt and MAPK signaling pathway in synovial mesenchymal stem cells
Weiwei Zheng, Xueping Gu, Xingwei Sun, Qin Wu & Hu Dan
Pages: 2641-2649
Published online: 26 Jun 2019
AbstractforFAK mediates BMP9-induced osteogenic differentiation via Wnt and MAPK signaling pathway in synovial mesenchymal stem cells | Full Text | References | PDF (1.7 MB) | EPUB
  • 1996 Views
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Article
Serum miR-663 expression and the diagnostic value in colorectal cancer
Ning Wang, Liyi Zeng, Zhaoxia Li, Yanfang Zhen & Huoming Chen
Pages: 2650-2653
Published online: 26 Jun 2019
AbstractforSerum miR-663 expression and the diagnostic value in colorectal cancer | Full Text | References | PDF (503 KB) | EPUB
  • 1678 Views
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Article
Emodin protects against lipopolysaccharide-induced inflammatory injury in HaCaT cells through upregulation of miR-21
Yanping Song, Xueling Cui, Ruilan Zhao, Lanying Hu, Yanjun Li & Cuiling Liu
Pages: 2654-2661
Published online: 28 Jun 2019
AbstractforEmodin protects against lipopolysaccharide-induced inflammatory injury in HaCaT cells through upregulation of miR-21 | Full Text | References | PDF (1.2 MB) | EPUB
  • 2999 Views
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Retracted Article

Article
RETRACTED ARTICLE: Shikonin inhibits proliferation, migration, invasion and promotes apoptosis in NCI-N87 cells via inhibition of PI3K/AKT signal pathway
Liushun Jia, Zhen Zhu, Hongbo Li & Yaofeng Li
Pages: 2662-2669
Published online: 01 Jul 2019
AbstractforRETRACTED ARTICLE: Shikonin inhibits proliferation, migration, invasion and promotes apoptosis in NCI-N87 cells via inhibition of PI3K/AKT signal pathway | PDF (2.6 MB)
  • 2109 Views
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Research Article

Article
Silencing long non-coding RNA SNHG6 restrains proliferation, migration and invasion of Wilms’ tumour cell lines by regulating miR-15a
Limin Su, Aiying Wu, Weitong Zhang & Xianchun Kong
Pages: 2670-2677
Published online: 01 Jul 2019
AbstractforSilencing long non-coding RNA SNHG6 restrains proliferation, migration and invasion of Wilms’ tumour cell lines by regulating miR-15a | Full Text | References | PDF (1.1 MB) | EPUB
  • 1523 Views
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Article
Emodin relieves hypoxia-triggered injury via elevation of microRNA-25 in PC-12 cells
Mingjuan Cao, Yuqing Fang, Wei Jia, Yao Wang, Jingyi Sun & Dingbo Tao
Pages: 2678-2687
Published online: 01 Jul 2019
AbstractforEmodin relieves hypoxia-triggered injury via elevation of microRNA-25 in PC-12 cells | Full Text | References | PDF (1.3 MB) | EPUB
  • 1758 Views
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Retracted Article

Article
RETRACTED ARTICLE: Amygdalin reduces lipopolysaccharide-induced chronic liver injury in rats by down-regulating PI3K/AKT, JAK2/STAT3 and NF-κB signalling pathways
Yang Yang, Jie Zhao, Xiaoqin Song, Lifeng Li, Fuqin Li, Jia Shang & Wei-Wei Wang
Pages: 2688-2697
Published online: 01 Jul 2019
AbstractforRETRACTED ARTICLE: Amygdalin reduces lipopolysaccharide-induced chronic liver injury in rats by down-regulating PI3K/AKT, JAK2/STAT3 and NF-κB signalling pathways | PDF (2.9 MB)
  • 1855 Views
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Article
RETRACTED ARTICLE: Long non-coding RNA H19 down-regulates miR-181a to facilitate endothelial angiogenic function
Aidong Zhu, Lifen Chu, Qiuju Ma & Yu Li
Pages: 2698-2705
Published online: 03 Jul 2019
AbstractforRETRACTED ARTICLE: Long non-coding RNA H19 down-regulates miR-181a to facilitate endothelial angiogenic function | PDF (2.1 MB)
  • 1782 Views
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Research Article

Article
Characterization of DNA hydroxymethylation profile in cervical cancer
Jing Wang, Yi Su, Yongju Tian, Yan Ding & Xiuli Wang
Pages: 2706-2714
Published online: 04 Jul 2019
AbstractforCharacterization of DNA hydroxymethylation profile in cervical cancer | Full Text | References | PDF (1.2 MB) | EPUB
  • 3331 Views
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Article
HOXC6 in the prognosis of prostate cancer
Junyu Zhou, Xiaogang Yang, Peng Song, Hongwei Wang & Xiumei Wang
Pages: 2715-2720
Published online: 04 Jul 2019
AbstractforHOXC6 in the prognosis of prostate cancer | Full Text | References | PDF (687.1 KB) | EPUB
  • 2997 Views
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Article
Magnetite nanoparticle as a support for stabilization of chondroitinase ABCI
Hossein Askaripour, Manouchehr Vossoughi, Khosro Khajeh & Iran Alemzadeh
Pages: 2721-2728
Published online: 05 Jul 2019
AbstractforMagnetite nanoparticle as a support for stabilization of chondroitinase ABCI | Full Text | References | PDF (1.1 MB) | EPUB
  • 1589 Views
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Article
Baicalein blocked cervical carcinoma cell proliferation by targeting CCND1 via Wnt/β-catenin signaling pathway
Xiulian Xia, Jiyi Xia, Hai Yang, Yan Li, Shengyue Liu, Yong Cao, Li Tang & Xiaolan Yu
Pages: 2729-2736
Published online: 08 Jul 2019
AbstractforBaicalein blocked cervical carcinoma cell proliferation by targeting CCND1 via Wnt/β-catenin signaling pathway | Full Text | References | PDF (1.3 MB) | EPUB
  • 1931 Views
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Article
Green synthesis of gold nanoparticles using a Cordyceps militaris extract and their antiproliferative effect in liver cancer cells (HepG2)
Yujiang Ji, Yang Cao & Yong Song
Pages: 2737-2745
Published online: 14 Jul 2019
AbstractforGreen synthesis of gold nanoparticles using a Cordyceps militaris extract and their antiproliferative effect in liver cancer cells (HepG2) | Full Text | References | PDF (1.1 MB) | EPUB
  • 3550 Views
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Article
Puerarin attenuates hypoxia-resulted damages in neural stem cells by up-regulating microRNA-214
Baoying Wang, Wenna Ma & Huiyu Yang
Pages: 2746-2753
Published online: 08 Jul 2019
AbstractforPuerarin attenuates hypoxia-resulted damages in neural stem cells by up-regulating microRNA-214 | Full Text | References | PDF (1 MB) | EPUB
  • 1609 Views
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Article
ASF1A regulates H4Y72 phosphorylation and promotes autophagy in colon cancer cells via a kinase activity
Fei Qiu, Yun Wang, Xianqun Chu & Jing Wang
Pages: 2754-2763
Published online: 09 Jul 2019
AbstractforASF1A regulates H4Y72 phosphorylation and promotes autophagy in colon cancer cells via a kinase activity | Full Text | References | PDF (1.1 MB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: Long noncoding RNA HAGLROS regulates apoptosis and autophagy in Parkinson’s disease via regulating miR-100/ATG10 axis and PI3K/Akt/mTOR pathway activation
Tao Peng, Xiaoyan Liu, Jingtao Wang, Yu Liu, Zhenqiang Fu, Xingrong Ma, Junmin Li, Guifang Sun, Yangfei Ji, Jingjing Lu, Wencui Wan & Hong Lu
Pages: 2764-2774
Published online: 12 Jul 2019
AbstractforRETRACTED ARTICLE: Long noncoding RNA HAGLROS regulates apoptosis and autophagy in Parkinson’s disease via regulating miR-100/ATG10 axis and PI3K/Akt/mTOR pathway activation | PDF (3.2 MB)
  • 2738 Views
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Research Article

Article
Tofacitinib inhibits ox-LDL-induced adhesion of THP-1 monocytes to endothelial cells
Xiaoyang Yang, Mengjie Wan, Zhiyong Cheng, Zhiming Wang & Qingxia Wu
Pages: 2775-2782
Published online: 08 Jul 2019
AbstractforTofacitinib inhibits ox-LDL-induced adhesion of THP-1 monocytes to endothelial cells | Full Text | References | PDF (923.7 KB) | EPUB
  • 2675 Views
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Article
Glioblastoma U-87MG tumour cells suppressed by ZnO folic acid-conjugated nanoparticles: an in vitro study
Zahra Hamod Marfavi, Mona Farhadi, Seyed Behnamedin Jameie, Masoomeh Zahmatkeshan, Vahid Pirhajati & Manasadat Jameie
Pages: 2783-2790
Published online: 09 Jul 2019
AbstractforGlioblastoma U-87MG tumour cells suppressed by ZnO folic acid-conjugated nanoparticles: an in vitro study | Full Text | References | PDF (967.8 KB) | EPUB
  • 2467 Views
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Article
microRNA-103 promotes LPS-induced inflammatory injury by targeting c-Myc in HK-2 cells
Wei Zhang, Wenyan Deng & Yingying Wang
Pages: 2791-2799
Published online: 08 Jul 2019
AbstractformicroRNA-103 promotes LPS-induced inflammatory injury by targeting c-Myc in HK-2 cells | Full Text | References | PDF (1.2 MB) | EPUB
  • 1972 Views
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Review

Review
MicroRNA-based potential diagnostic, prognostic and therapeutic applications in triple-negative breast cancer
Qian Tang, Hu Ouyang, Dongxiu He, Cuiyun Yu & Guotao Tang
Pages: 2800-2809
Published online: 09 Jul 2019
AbstractforMicroRNA-based potential diagnostic, prognostic and therapeutic applications in triple-negative breast cancer | Full Text | References | PDF (969.1 KB) | EPUB
  • 4240 Views
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Review
Research progress on therapeutic targeting of quiescent cancer cells
Jinhua Zhang, Jing Si, Lu Gan, Cuixia Di, Yi Xie, Chao Sun, Hongyan Li, Menghuan Guo & Hong Zhang
Pages: 2810-2819
Published online: 09 Jul 2019
AbstractforResearch progress on therapeutic targeting of quiescent cancer cells | Full Text | References | PDF (943.5 KB) | EPUB
  • 4790 Views
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Research Article

Article
Transcriptome profiling of cervical cancer cells acquired resistance to cisplatin by deep sequencing
Yamin Wang, Linna Liu & Zhong Chen
Pages: 2820-2829
Published online: 11 Jul 2019
AbstractforTranscriptome profiling of cervical cancer cells acquired resistance to cisplatin by deep sequencing | Full Text | References | PDF (1.8 MB) | EPUB
  • 2986 Views
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Article
Gold nano-particles (AuNPs) carrying miR-326 targets PDK1/AKT/c-myc axis in hepatocellular carcinoma
Yichao Mo, Longguang He, Zeru Lai, Zhiheng Wan, Qinshou Chen, Sibo Pan, Liangfu Li, Dasheng Li, Junwei Huang, Fan Xue & Siyao Che
Pages: 2830-2837
Published online: 12 Jul 2019
AbstractforGold nano-particles (AuNPs) carrying miR-326 targets PDK1/AKT/c-myc axis in hepatocellular carcinoma | Full Text | References | PDF (1.1 MB) | EPUB
  • 1073 Views
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Free Access
Article
Micro/nanostructured TiO2/ZnO coating enhances osteogenic activity of SaOS-2 cells
Ranran Zhang, Nan Xu, Xujie Liu, Xing Yang, Hao Yan, Jing Ma, Qingling Feng & Zhijian Shen
Pages: 2838-2845
Published online: 15 Jul 2019
AbstractforMicro/nanostructured TiO2/ZnO coating enhances osteogenic activity of SaOS-2 cells | Full Text | References | PDF (1.4 MB) | EPUB
  • 2201 Views
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Article
Synthesis of silver nanoparticles (AgNPs) from leaf extract of Salvia miltiorrhiza and its anticancer potential in human prostate cancer LNCaP cell lines
Ke Zhang, Xiaodong Liu, Samson Oliver Abraham Samuel Ravi, Arunkumar Ramachandran, Ibrahim Abdel Aziz Ibrahim, Anmar M. Nassir & Jiapei Yao
Pages: 2846-2854
Published online: 12 Jul 2019
AbstractforSynthesis of silver nanoparticles (AgNPs) from leaf extract of Salvia miltiorrhiza and its anticancer potential in human prostate cancer LNCaP cell lines | Full Text | References | PDF (1.4 MB) | EPUB
  • 3467 Views
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Retracted Article

Article
RETRACTED ARTICLE: Involvement of NORAD/miR-608/STAT3 axis in carcinostasis effects of physcion 8-O-β-glucopyranoside on ovarian cancer cells
Xiaohong Yang, Yimin Yan, Yuhuan Chen, Jingwen Li & Jing Yang
Pages: 2855-2865
Published online: 12 Jul 2019
AbstractforRETRACTED ARTICLE: Involvement of NORAD/miR-608/STAT3 axis in carcinostasis effects of physcion 8-O-β-glucopyranoside on ovarian cancer cells | PDF (3.9 MB)
  • 1658 Views
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Research Article

Article
Lidocaine inhibits proliferation and metastasis of lung cancer cell via regulation of miR-539/EGFR axis
Hai Sun & Yan Sun
Pages: 2866-2874
Published online: 12 Jul 2019
AbstractforLidocaine inhibits proliferation and metastasis of lung cancer cell via regulation of miR-539/EGFR axis | Full Text | References | PDF (1.6 MB) | EPUB
  • 2765 Views
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Article
Geniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p
Shaolong Ma, Chao Zhang, Ziyan Zhang, Yuxuan Dai, Rui Gu & Rui Jiang
Pages: 2875-2881
Published online: 15 Jul 2019
AbstractforGeniposide protects PC12 cells from lipopolysaccharide-evoked inflammatory injury via up-regulation of miR-145-5p | Full Text | References | PDF (941.7 KB) | EPUB
  • 2699 Views
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Article
Ras-AKT signaling represses the phosphorylation of histone H1.5 at threonine 10 via GSK3 to promote the progression of glioma
Ben Sang, Jianjing Sun, Dongxu Yang, Zhen Xu & Yuzhen Wei
Pages: 2882-2890
Published online: 15 Jul 2019
AbstractforRas-AKT signaling represses the phosphorylation of histone H1.5 at threonine 10 via GSK3 to promote the progression of glioma | Full Text | References | PDF (1.2 MB) | EPUB
  • 2195 Views
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Article
p300 Acetylates JHDM1A to inhibit osteosarcoma carcinogenesis
Yongkun Wang, Baozhen Sun, Qiao Zhang, Hang Dong & Jingzhe Zhang
Pages: 2891-2899
Published online: 15 Jul 2019
Abstractforp300 Acetylates JHDM1A to inhibit osteosarcoma carcinogenesis | Full Text | References | PDF (1.1 MB) | EPUB
  • 1719 Views
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Article
The protective effects of lycopus lucidus turcz in diabetic retinopathy and its possible mechanisms
Jinlu Liu, Sai Bhuvanagiri & Xiaohan Qu
Pages: 2900-2908
Published online: 15 Jul 2019
AbstractforThe protective effects of lycopus lucidus turcz in diabetic retinopathy and its possible mechanisms | Full Text | References | PDF (1.5 MB) | EPUB
  • 1980 Views
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Retracted Article

Article
RETRACTED ARTICLE: Quercetin supports cell viability and inhibits apoptosis in cardiocytes by down-regulating miR-199a
Gongliang Guo, Licheng Gong, Liqun Sun & Haiming Xu
Pages: 2909-2916
Published online: 15 Jul 2019
AbstractforRETRACTED ARTICLE: Quercetin supports cell viability and inhibits apoptosis in cardiocytes by down-regulating miR-199a | PDF (2 MB)
  • 1358 Views
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Correction

Correction
Correction
Page: 2917
Published online: 17 Jul 2019
CitationforCorrection | Full Text | PDF (196.6 KB) | EPUB
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Article
Bone marrow mesenchymal stem cell-derived exosome uptake and retrograde transport can occur at peripheral nerve endings
Rui Ren, Xiao-Hong Tan, Jiu-Hong Zhao, Quan-Peng Zhang, Xian-Fang Zhang, Zhi-Jian Ma, Ya-Nan Peng, Qi-Bing Liu, Hai-Ying Zhang, Yun-Qing Li, Rui He, Zhen-Qiang Zhao & Xi-Nan Yi
Pages: 2918-2929
Published online: 18 Jul 2019
AbstractforBone marrow mesenchymal stem cell-derived exosome uptake and retrograde transport can occur at peripheral nerve endings | Full Text | References | PDF (2 MB) | EPUB
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Article
Cinnamon attenuates adiposity and affects the expression of metabolic genes in Diet-Induced obesity model of zebrafish
Navrinder Kaur, Heerak Chugh, Vartika Tomar, Meena Kishore Sakharkar, Sujata K. Dass & Ramesh Chandra
Pages: 2930-2939
Published online: 18 Jul 2019
AbstractforCinnamon attenuates adiposity and affects the expression of metabolic genes in Diet-Induced obesity model of zebrafish | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Arbutin protects HK-2 cells against high glucose-induced apoptosis and autophagy by up-regulating microRNA-27a
Lina Lv, Jing Zhang, Fengqun Tian, Xia Li, Dandan Li & Xiulian Yu
Pages: 2940-2947
Published online: 19 Jul 2019
AbstractforArbutin protects HK-2 cells against high glucose-induced apoptosis and autophagy by up-regulating microRNA-27a | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Roles of CaMKIIβ in the neurotoxicity induced by ropivacaine hydrochloride in dorsal root ganglion
Xianjie Wen, Yiqun Li, Xingqing Liu, Can Sun, Jinbing Lin, Wenli Zhang, Yabin Wu & Xiaoping Wang
Pages: 2948-2956
Published online: 18 Jul 2019
AbstractforRoles of CaMKIIβ in the neurotoxicity induced by ropivacaine hydrochloride in dorsal root ganglion | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Large-scale quantitative genomics analyzes the circRNA expression profile and identifies the key circRNA in regulating cell proliferation during the proliferation phase of rat LR
Xueqiang Guo, Wei Jin, Cuifang Chang, Yi Ding, Yahao Wang, Lifei Li, Yanhui Chen, Jingbo Zhang, Cunshuan Xu, Guangwen Chen & Jianlin Guo
Pages: 2957-2966
Published online: 18 Jul 2019
AbstractforLarge-scale quantitative genomics analyzes the circRNA expression profile and identifies the key circRNA in regulating cell proliferation during the proliferation phase of rat LR | Full Text | References | PDF (2.1 MB) | EPUB
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Article
Ginsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells
Jianqiang Zhang, Jing Wang, Xinan Wu & Yuhui Wei
Pages: 2967-2971
Published online: 17 Jul 2019
AbstractforGinsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells | Full Text | References | PDF (663.6 KB) | EPUB
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Original Articles

Article
Protective effect of ginsenoside Rg1 on attenuating anti-GBM glomerular nephritis by activating NRF2 signalling
Xiaojuan Guo, Jingyuan Zhang, Min Liu & Guo Chen Zhao
Pages: 2972-2979
Published online: 19 Jul 2019
AbstractforProtective effect of ginsenoside Rg1 on attenuating anti-GBM glomerular nephritis by activating NRF2 signalling | Full Text | References | PDF (1.1 MB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: Bilobalide protects H9c2 cell from oxygen-glucose-deprivation-caused damage via upregulation of miR-27a
Ailin Cao & Xiangting Li
Pages: 2980-2988
Published online: 19 Jul 2019
AbstractforRETRACTED ARTICLE: Bilobalide protects H9c2 cell from oxygen-glucose-deprivation-caused damage via upregulation of miR-27a | PDF (2.5 MB)
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Research Article

Article
Correlation between HCN4 gene polymorphisms and lone atrial fibrillation risk
Xiao-Hong Li, Ya-Min Hu, Guang-Li Yin & Ping Wu
Pages: 2989-2993
Published online: 18 Jul 2019
AbstractforCorrelation between HCN4 gene polymorphisms and lone atrial fibrillation risk | Full Text | References | PDF (551.5 KB) | EPUB
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Article
RETRACTED ARTICLE: Long non-coding RNA CCAT2 acts as an oncogene in osteosarcoma through regulation of miR-200b/VEGF
Juntao Liu, Dehai Kong, Deping Sun & Jianmin Li
Pages: 2994-3003
Published online: 19 Jul 2019
AbstractforRETRACTED ARTICLE: Long non-coding RNA CCAT2 acts as an oncogene in osteosarcoma through regulation of miR-200b/VEGF | PDF (2.6 MB)
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Research Article

Article
TNF-α induces apoptosis of human nucleus pulposus cells via activating the TRIM14/NF-κB signalling pathway
Hao Zhu, Bao Sun & Qiang Shen
Pages: 3004-3012
Published online: 19 Jul 2019
AbstractforTNF-α induces apoptosis of human nucleus pulposus cells via activating the TRIM14/NF-κB signalling pathway | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Upregulation of long noncoding RNA RP4 exacerbates hypoxia injury in cardiomyocytes through regulating miR-939/Bnip3/Wnt/β-catenin pathway
Jingfeng Rong, Jijie Xu, Qian Liu, Yaoyao Wu, Honglin Guo, Ting Mu, Hua Zhou & Hao Chi
Pages: 3013-3020
Published online: 19 Jul 2019
AbstractforUpregulation of long noncoding RNA RP4 exacerbates hypoxia injury in cardiomyocytes through regulating miR-939/Bnip3/Wnt/β-catenin pathway | Full Text | References | PDF (1.3 MB) | EPUB
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Article
CD24 expression indicates healthier phenotype and less tendency of cellular senescence in human nucleus pulposus cells
Shu-Hua Yang, Ming-Hsiao Hu, Chang-Chin Wu, Chih-Wei Chen, Yuan-Hui Sun & Kai-Chiang Yang
Pages: 3021-3028
Published online: 23 Jul 2019
AbstractforCD24 expression indicates healthier phenotype and less tendency of cellular senescence in human nucleus pulposus cells | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Synthesis and characterization of gold nanoparticles from Marsdenia tenacissima and its anticancer activity of liver cancer HepG2 cells
Lupeng Li, Wenzhi Zhang, Vidya Devanatha Desikan Seshadri & Guangshao Cao
Pages: 3029-3036
Published online: 22 Jul 2019
AbstractforSynthesis and characterization of gold nanoparticles from Marsdenia tenacissima and its anticancer activity of liver cancer HepG2 cells | Full Text | References | PDF (1.2 MB) | EPUB
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Article
RETRACTED ARTICLE: MiR-29a inhibits the progression of oral squamous cell carcinoma by targeting Wnt/β-catenin signalling pathway
Chao Huang, Lili Wang, Hongguang Song & Cungang Wu
Pages: 3037-3042
Published online: 25 Jul 2019
AbstractforRETRACTED ARTICLE: MiR-29a inhibits the progression of oral squamous cell carcinoma by targeting Wnt/β-catenin signalling pathway | PDF (1.5 MB)
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Article
RETRACTED ARTICLE: Upregulation of lncRNA HAGLROS enhances the development of nasopharyngeal carcinoma via modulating miR-100/ATG14 axis-mediated PI3K/AKT/mTOR signals
Wei Zhang, Yanle Zhang & Shoumin Xi
Pages: 3043-3052
Published online: 23 Jul 2019
AbstractforRETRACTED ARTICLE: Upregulation of lncRNA HAGLROS enhances the development of nasopharyngeal carcinoma via modulating miR-100/ATG14 axis-mediated PI3K/AKT/mTOR signals | PDF (3.1 MB)
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Article
The prognostic roles of cyclooxygenase-2 for patients with basal cell carcinoma
Yang Chen & Jilong Liu
Pages: 3053-3057
Published online: 23 Jul 2019
AbstractforThe prognostic roles of cyclooxygenase-2 for patients with basal cell carcinoma | Full Text | References | PDF (600.7 KB) | EPUB
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Article
Synergistic effects of polyaniline and pulsed electromagnetic field to stem cells osteogenic differentiation on polyvinylidene fluoride scaffold
Ali Mirzaei, Ehsan Saburi, Seyed Ehsan Enderami, Matineh Barati Bagherabad, Seyedeh Elnaz Enderami, Mahmood Chokami, Abbas Shapouri Moghadam, Reza Salarinia, Abdolreza Ardeshirylajimi, Vahid Mansouri & Fatemeh Soleimanifar
Pages: 3058-3066
Published online: 24 Jul 2019
AbstractforSynergistic effects of polyaniline and pulsed electromagnetic field to stem cells osteogenic differentiation on polyvinylidene fluoride scaffold | Full Text | References | PDF (1.4 MB) | EPUB
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Article

Article
The expression level and clinical significance of lncRNA X91348 in hepatocellular carcinoma
Zhen Zeng, Jinghui Dong, Yinyin Li, Zheng Dong, Ze Liu, Jiagan Huang, Yonggang Wang, Yunhuan Zhen & Yinying Lu
Pages: 3067-3071
Published online: 26 Jul 2019
AbstractforThe expression level and clinical significance of lncRNA X91348 in hepatocellular carcinoma | Full Text | References | PDF (575.9 KB) | EPUB
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Research Article

Article
miR-34a inhibits proliferation, migration and invasion of paediatric neuroblastoma cells via targeting HNF4α
Zhiping Li & Huijun Chen
Pages: 3072-3078
Published online: 25 Jul 2019
AbstractformiR-34a inhibits proliferation, migration and invasion of paediatric neuroblastoma cells via targeting HNF4α | Full Text | References | PDF (932.6 KB) | EPUB
  • 1929 Views
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Article
Cisplatin-functionalized three-dimensional magnetic SBA-16 for treating breast cancer cells (MCF-7)
Munther Alomari, B. Rabindran Jermy, Vijaya Ravinayagam, Sultan Akhtar, Sarah Ameen Almofty, Suriya Rehman, Hiba Bahmdan, Sayed AbdulAzeez & J. Francis Borgio
Pages: 3079-3086
Published online: 27 Jul 2019
AbstractforCisplatin-functionalized three-dimensional magnetic SBA-16 for treating breast cancer cells (MCF-7) | Full Text | References | PDF (1.6 MB) | EPUB
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Article
The efficacy and potential mechanism of cnidium lactone to inhibit osteoclast differentiation
Jun-Yang Liang, Wen-Liang Wu, Yun-Xia Chen & Haichun Liu
Pages: 3087-3093
Published online: 25 Jul 2019
AbstractforThe efficacy and potential mechanism of cnidium lactone to inhibit osteoclast differentiation | Full Text | References | PDF (1.3 MB) | EPUB
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Article

Article
Progress of titanium strut for cervical reconstruction with nano-graphene oxide loaded hydroxyapatite/polyamide composite and interbody fusion after corpectomy with anterior plate fixation
Hongli Pang, Hailong Tian, Shaobo Qiu, Ning Wang & Yu-Qiang Wang
Pages: 3094-3100
Published online: 25 Jul 2019
AbstractforProgress of titanium strut for cervical reconstruction with nano-graphene oxide loaded hydroxyapatite/polyamide composite and interbody fusion after corpectomy with anterior plate fixation | Full Text | References | PDF (943.6 KB) | EPUB
  • 1882 Views
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Article
Gold nano particles synthesized from Magnolia officinalis and anticancer activity in A549 lung cancer cells
Yuanyuan Zheng, Jianwu Zhang, Rui Zhang, Zhuang Luo, Chu Wang & Shaoqing Shi
Pages: 3101-3109
Published online: 25 Jul 2019
AbstractforGold nano particles synthesized from Magnolia officinalis and anticancer activity in A549 lung cancer cells | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Clinical efficacy and safety of statin treatment after carotid artery stenting
Lingya Qiao, Shibo Wang, Qiang Jia, Ji Bian, Yimu Fan & Xiaolin Xu
Pages: 3110-3115
Published online: 27 Jul 2019
AbstractforClinical efficacy and safety of statin treatment after carotid artery stenting | Full Text | References | PDF (574.6 KB) | EPUB
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Article
Association between the FMR1 CGG repeat lengths and the severity of idiopathic primary ovarian insufficiency: a meta analysis
Jing Huang, Wenxiang Zhang, Yingchun Liu, Ying Liu, Jing Wang & Hong Jiang
Pages: 3116-3122
Published online: 27 Jul 2019
AbstractforAssociation between the FMR1 CGG repeat lengths and the severity of idiopathic primary ovarian insufficiency: a meta analysis | Full Text | References | PDF (987.6 KB) | EPUB
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Article
Prolonged functional life span of artificial red cells in blood circulation by repeated methylene blue injections
Hiromi Sakai & Cassandra Leong
Pages: 3123-3128
Published online: 27 Jul 2019
AbstractforProlonged functional life span of artificial red cells in blood circulation by repeated methylene blue injections | Full Text | References | PDF (803.6 KB) | EPUB
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Article

Article
Long non-coding RNA NEAT1 inhibits oxidative stress-induced vascular endothelial cell injury by activating the miR-181d-5p/CDKN3 axis
Min Zhang, Xueting Wang, Jing Yao & Zhaohui Qiu
Pages: 3129-3137
Published online: 29 Jul 2019
AbstractforLong non-coding RNA NEAT1 inhibits oxidative stress-induced vascular endothelial cell injury by activating the miR-181d-5p/CDKN3 axis | Full Text | References | PDF (1.3 MB) | EPUB
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Article
Effect of polymorphism on IL1A to cancer susceptibility: Evidence based on 34,016 subjects
Haoran Xia, Yiding Chen, Jialin Meng & Chaozhao Liang
Pages: 3138-3152
Published online: 30 Jul 2019
AbstractforEffect of polymorphism on IL1A to cancer susceptibility: Evidence based on 34,016 subjects | Full Text | References | PDF (1.9 MB) | EPUB
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Article
Alkannin restrains oral squamous carcinoma cell growth, migration and invasion by regulating microRNA-9/RECK axis
Yulong Mao, Weiwei Zhang, Ronghe Zhang & Jinhua Zuo
Pages: 3153-3162
Published online: 26 Jul 2019
AbstractforAlkannin restrains oral squamous carcinoma cell growth, migration and invasion by regulating microRNA-9/RECK axis | Full Text | References | PDF (1.4 MB) | EPUB
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Article
RETRACTED ARTICLE: MicroRNA-183 affects the development of gastric cancer by regulating autophagy via MALAT1-miR-183-SIRT1 axis and PI3K/AKT/mTOR signals
Huiying Li, Chengyan He, Xuekui Wang, Hai Wang, Guangxian Nan & Ling Fang
Pages: 3163-3171
Published online: 26 Jul 2019
AbstractforRETRACTED ARTICLE: MicroRNA-183 affects the development of gastric cancer by regulating autophagy via MALAT1-miR-183-SIRT1 axis and PI3K/AKT/mTOR signals | PDF (2.4 MB)
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Research Article

Article
Long non-coding RNA SDPR-AS affects the development of non-small cell lung cancer by regulating SDPR through p38 MAPK/ERK signals
Junfei Zhu, Lili Wang & Ruomin Liao
Pages: 3172-3179
Published online: 27 Jul 2019
AbstractforLong non-coding RNA SDPR-AS affects the development of non-small cell lung cancer by regulating SDPR through p38 MAPK/ERK signals | Full Text | References | PDF (1.1 MB) | EPUB
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Article
SOX13 dependent PAX8 expression promotes the proliferation of gastric carcinoma cells
Liang-Yu Bie, Dan Li, Yan Wei, Ning Li, Xiao-Bing Chen & Su-Xia Luo
Pages: 3180-3187
Published online: 27 Jul 2019
AbstractforSOX13 dependent PAX8 expression promotes the proliferation of gastric carcinoma cells | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Mechanism of miR-15a regulating the growth and apoptosis of human knee joint chondrocytes by targeting SMAD2
Tengjun Ma, Yan Cheng & Liang Tan
Pages: 3188-3193
Published online: 01 Aug 2019
AbstractforMechanism of miR-15a regulating the growth and apoptosis of human knee joint chondrocytes by targeting SMAD2 | Full Text | References | PDF (747.9 KB) | EPUB
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Article
Angelica polysaccharide mitigates lipopolysaccharide-evoked inflammatory injury by regulating microRNA-10a in neuronal cell line HT22
Yuni Zhou, Xiaoqian Guo, Weimei Chen & Jun Liu
Pages: 3194-3201
Published online: 28 Jul 2019
AbstractforAngelica polysaccharide mitigates lipopolysaccharide-evoked inflammatory injury by regulating microRNA-10a in neuronal cell line HT22 | Full Text | References | PDF (991.9 KB) | EPUB
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Article
Baicalein inhibits proliferation and collagen synthesis of mice fibroblast cell line NIH/3T3 by regulation of miR-9/insulin-like growth factor-1 axis
Li Yang, Xueli Li, Shoumin Zhang, Jinghui Song & Tingting Zhu
Pages: 3202-3211
Published online: 30 Jul 2019
AbstractforBaicalein inhibits proliferation and collagen synthesis of mice fibroblast cell line NIH/3T3 by regulation of miR-9/insulin-like growth factor-1 axis | Full Text | References | PDF (1.2 MB) | EPUB
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Article
Green synthesis of silver nanoparticles from Alpinia officinarum mitigates cisplatin-induced nephrotoxicity via down-regulating apoptotic pathway in rats
Zhiping Zhang, Guangda Xin, Guangyu Zhou, Qianyu Li, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Dayu Wang & Feng Liu
Pages: 3212-3221
Published online: 30 Jul 2019
AbstractforGreen synthesis of silver nanoparticles from Alpinia officinarum mitigates cisplatin-induced nephrotoxicity via down-regulating apoptotic pathway in rats | Full Text | References | PDF (1.3 MB) | EPUB
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Article

Article
Preparation, characterization and in vitro evaluation of PEGylated nanoliposomal containing etoposide on lung cancer
Fatemeh Zare Kazemabadi, Amir Heydarinasab, Azim Akbarzadeh & Mehdi Ardjmand
Pages: 3222-3230
Published online: 02 Aug 2019
AbstractforPreparation, characterization and in vitro evaluation of PEGylated nanoliposomal containing etoposide on lung cancer | Full Text | References | PDF (1.7 MB) | EPUB
  • 3139 Views
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Article
SHP2 inhibitor specifically suppresses the stemness of KRAS-mutant non-small cell lung cancer cells
Lei Jiang, Weiping Xu, Yi Chen & Yue Zhang
Pages: 3231-3238
Published online: 02 Aug 2019
AbstractforSHP2 inhibitor specifically suppresses the stemness of KRAS-mutant non-small cell lung cancer cells | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Saxagliptin suppresses degradation of type II collagen and aggrecan in primary human chondrocytes: a therapeutic implication in osteoarthritis
Ning Hu, Xuan Gong, Shijie Yin, Qi Li, Hao Chen, Yuwan Li, Feilong Li, Leilei Qing, Jianye Yang, Sizheng Zhu, Jiawei Wang & Junchao Li
Pages: 3239-3245
Published online: 31 Jul 2019
AbstractforSaxagliptin suppresses degradation of type II collagen and aggrecan in primary human chondrocytes: a therapeutic implication in osteoarthritis | Full Text | References | PDF (883.3 KB) | EPUB
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Article
Identification of lncRNA biomarkers in lung squamous cell carcinoma using comprehensive analysis of lncRNA mediated ceRNA network
Rui Li, Yi-E Yang, Jia Jin, Meng-Yu Zhang, Xiao Liu, Xiao-Xia Liu, Yun-Hong Yin & Yi-Qing Qu
Pages: 3246-3258
Published online: 31 Jul 2019
AbstractforIdentification of lncRNA biomarkers in lung squamous cell carcinoma using comprehensive analysis of lncRNA mediated ceRNA network | Full Text | References | PDF (2.2 MB) | EPUB
  • 3291 Views
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Article

Article
Lunasin abrogates the expression of matrix metalloproteinases and reduction of type II collagen
Weihua Dai, Zhiyong Liang, Hongbo Liu, Guangzong Zhao & Chunfang Ju
Pages: 3259-3264
Published online: 01 Aug 2019
AbstractforLunasin abrogates the expression of matrix metalloproteinases and reduction of type II collagen | Full Text | References | PDF (820.5 KB) | EPUB
  • 1994 Views
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Article
Luteolin exhibits anti-breast cancer property through up-regulating miR-203
Guanglei Gao, Rongli Ge, Yuzhou Li & Shengcui Liu
Pages: 3265-3271
Published online: 01 Aug 2019
AbstractforLuteolin exhibits anti-breast cancer property through up-regulating miR-203 | Full Text | References | PDF (1.2 MB) | EPUB
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Article
The diagnostic effect of sequential detection of ADA screening and T-SPOT assay in pleural effusion patients
Mingxia Feng, Fenfen Sun, Fang Wang & Guoqiang Cao
Pages: 3272-3277
Published online: 05 Aug 2019
AbstractforThe diagnostic effect of sequential detection of ADA screening and T-SPOT assay in pleural effusion patients | Full Text | References | PDF (661.6 KB) | EPUB
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Article
MiR-638 suppresses the progression of oral squamous cell carcinoma through wnt/β-catenin pathway by targeting phospholipase D1
Kai-Liang Tang, Han-Ying Tang, Yi- Du, Tian Tian & Shi-Jiang Xiong
Pages: 3278-3285
Published online: 05 Aug 2019
AbstractforMiR-638 suppresses the progression of oral squamous cell carcinoma through wnt/β-catenin pathway by targeting phospholipase D1 | Full Text | References | PDF (1.1 MB) | EPUB
  • 1351 Views
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Article
MiR-629-3p-induced downregulation of SFTPC promotes cell proliferation and predicts poor survival in lung adenocarcinoma
Bin Li, Yu-Qi Meng, Zheng Li, Ci Yin, Jun-Ping Lin, Duo-Jie Zhu & Shao-Bo Zhang
Pages: 3286-3296
Published online: 05 Aug 2019
AbstractforMiR-629-3p-induced downregulation of SFTPC promotes cell proliferation and predicts poor survival in lung adenocarcinoma | Full Text | References | PDF (1.9 MB) | EPUB
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Article

Article
Biologically synthesized green gold nanoparticles from Siberian ginseng induce growth-inhibitory effect on melanoma cells (B16)
Fenglian Wu, Jun Zhu, Guoliang Li, Jiaxin Wang, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan & Qingfu Zhang
Pages: 3297-3305
Published online: 05 Aug 2019
AbstractforBiologically synthesized green gold nanoparticles from Siberian ginseng induce growth-inhibitory effect on melanoma cells (B16) | Full Text | References | PDF (1.1 MB) | EPUB
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Article
RETRACTED ARTICLE: Sevoflurane suppresses migration and invasion of glioma cells by regulating miR-146b-5p and MMP16
Le Zhang, Jun Wang, Zhijie Fu, YanQiu Ai, Yanrong Li, Ying Wang & Yanping Wang
Pages: 3306-3314
Published online: 06 Aug 2019
AbstractforRETRACTED ARTICLE: Sevoflurane suppresses migration and invasion of glioma cells by regulating miR-146b-5p and MMP16 | PDF (2 MB)
  • 1647 Views
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Research Article

Article
Clinicopathological and prognostic value of LINC01296 in cancers: a meta-analysis
Wei Feng, Cui Zhai, Wenhua Shi, Qianqian Zhang, Xin Yan, Jian Wang, Qingting Wang & Manxiang Li
Pages: 3315-3321
Published online: 06 Aug 2019
AbstractforClinicopathological and prognostic value of LINC01296 in cancers: a meta-analysis | Full Text | References | PDF (943.4 KB) | EPUB
  • 1829 Views
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Article

Article
Long noncoding RNA DLEU1 aggravates osteosarcoma carcinogenesis via regulating the miR-671-5p/DDX5 axis
Xinxin Chen, Chengyong Zhang & Xiao Wang
Pages: 3322-3328
Published online: 05 Aug 2019
AbstractforLong noncoding RNA DLEU1 aggravates osteosarcoma carcinogenesis via regulating the miR-671-5p/DDX5 axis | Full Text | References | PDF (935.3 KB) | EPUB
  • 1719 Views
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Research Article

Article
The use of TLR2 modified BMSCs for enhanced bone regeneration in the inflammatory micro-environment
Qin Zhou, Xiaoyu Gu, Jiachen Dong, Chao Zhu, Zhen Cai, Dongmei He, Chi Yang, Ling Xu & Jiawei Zheng
Pages: 3329-3337
Published online: 06 Aug 2019
AbstractforThe use of TLR2 modified BMSCs for enhanced bone regeneration in the inflammatory micro-environment | Full Text | References | PDF (1.5 MB) | EPUB
  • 2672 Views
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Article
Characterization of synergistic antibacterial effect of silver nanoparticles and ebselen
Xueqing Chen, Heming Chen, Hongying Zhang, Yanjuan Peng, Fuchang Deng, Jiye Gao, Chunli Chai, Song Tang, Xin Zuo, Jun Lu & Huamao Du
Pages: 3338-3349
Published online: 07 Aug 2019
AbstractforCharacterization of synergistic antibacterial effect of silver nanoparticles and ebselen | Full Text | References | PDF (1.5 MB) | EPUB
  • 2457 Views
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Article
Silencing circular RNA circZNF609 restrains growth, migration and invasion by up-regulating microRNA-186-5p in prostate cancer
Chengjun Jin, Weiming Zhao, Zijian Zhang & Wanpeng Liu
Pages: 3350-3358
Published online: 07 Aug 2019
AbstractforSilencing circular RNA circZNF609 restrains growth, migration and invasion by up-regulating microRNA-186-5p in prostate cancer | Full Text | References | PDF (1.4 MB) | EPUB
  • 2178 Views
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Article
RETRACTED ARTICLE: The circular RNA circ-ITCH acts as a tumour suppressor in osteosarcoma via regulating miR-22
Chongmin Ren, Jia Liu, Bingxin Zheng, Peng Yan, Yuerong Sun & Bin Yue
Pages: 3359-3367
Published online: 07 Aug 2019
AbstractforRETRACTED ARTICLE: The circular RNA circ-ITCH acts as a tumour suppressor in osteosarcoma via regulating miR-22 | PDF (2.4 MB)
  • 1860 Views
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Research Article

Article
Knockdown of ANGPTL-4 inhibits inflammatory response and extracellular matrix accumulation in glomerular mesangial cells cultured under high glucose condition
Linfang Qin, Ruimin Zhang, Suxia Yang, Fang Chen & Jun Shi
Pages: 3368-3373
Published online: 07 Aug 2019
AbstractforKnockdown of ANGPTL-4 inhibits inflammatory response and extracellular matrix accumulation in glomerular mesangial cells cultured under high glucose condition | Full Text | References | PDF (750.4 KB) | EPUB
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Article
Sirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy
Hongliang Ying, Boda Ying, Jinrui Zhang & Daliang Kong
Pages: 3374-3381
Published online: 07 Aug 2019
AbstractforSirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy | Full Text | References | PDF (1.1 MB) | EPUB
  • 1919 Views
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Review

Review
Integrated metabolomics and 16S rRNA sequencing to investigate the regulation of Chinese yam on antibiotic-induced intestinal dysbiosis in rats
Yaping Sun, Tong Liu, Yanpo Si, Bing Cao, Yanli Zhang, Xiaoke Zheng & Weisheng Feng
Pages: 3382-3390
Published online: 19 Aug 2019
AbstractforIntegrated metabolomics and 16S rRNA sequencing to investigate the regulation of Chinese yam on antibiotic-induced intestinal dysbiosis in rats | Full Text | References | PDF (1.2 MB) | EPUB
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Research Article

Article
Evaluation of antiarthritic activity of nimbolide against Freund’s adjuvant induced arthritis in rats
Xin Cui, Ruijing Wang, Peimin Bian, Qingke Wu, Vidya Devanatha Desikan Seshadri & Lun Liu
Pages: 3391-3398
Published online: 08 Aug 2019
AbstractforEvaluation of antiarthritic activity of nimbolide against Freund’s adjuvant induced arthritis in rats | Full Text | References | PDF (1 MB) | EPUB
  • 6441 Views
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Correction

Correction
Correction
Page: 3399
Published online: 09 Aug 2019
CitationforCorrection | Full Text | PDF (178.5 KB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: Repression of lncRNA-SVUGP2 mediated by EZH2 contributes to the development of non-small cell lung cancer via brisking Wnt/β-catenin signal
Sen Wei, Jinghao Liu, Xin Li & Xingyu Liu
Pages: 3400-3409
Published online: 12 Aug 2019
AbstractforRETRACTED ARTICLE: Repression of lncRNA-SVUGP2 mediated by EZH2 contributes to the development of non-small cell lung cancer via brisking Wnt/β-catenin signal | PDF (3 MB)
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Research Article

Article
Circular RNA ZFR accelerates non-small cell lung cancer progression by acting as a miR-101-3p sponge to enhance CUL4B expression
Haifeng Zhang, Xiaolong Wang, Baoli Hu, Feng Zhang, Haitao Wei & Li Li
Pages: 3410-3416
Published online: 13 Aug 2019
AbstractforCircular RNA ZFR accelerates non-small cell lung cancer progression by acting as a miR-101-3p sponge to enhance CUL4B expression | Full Text | References | PDF (1.1 MB) | EPUB
  • 2200 Views
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Article
Methylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus
Lian Bai, Junwu Li, Mani Panagal, Biruntha M.Durairaj Sekar
Pages: 3417-3422
Published online: 13 Aug 2019
AbstractforMethylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus | Full Text | References | PDF (707.6 KB) | EPUB
  • 1970 Views
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Article

Article
Development of polypyrrole/collagen/nano-strontium substituted bioactive glass composite for boost sciatic nerve rejuvenation in vivo
Bo Lin, Guoqing Dun, Dongzhu Jin & Yaowu Du
Pages: 3423-3430
Published online: 11 Aug 2019
AbstractforDevelopment of polypyrrole/collagen/nano-strontium substituted bioactive glass composite for boost sciatic nerve rejuvenation in vivo | Full Text | References | PDF (1.3 MB) | EPUB
  • 1713 Views
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Article
Towards osteogenic differentiation of human dental pulp stem cells on PCL-PEG-PCL/zeolite nanofibrous scaffolds
Mahdieh Alipour, Marziyeh Aghazadeh, Abolfazl Akbarzadeh, Zahra Vafajoo, Zahra Aghazadeh & Vahideh Raeisdasteh Hokmabad
Pages: 3431-3437
Published online: 14 Aug 2019
AbstractforTowards osteogenic differentiation of human dental pulp stem cells on PCL-PEG-PCL/zeolite nanofibrous scaffolds | Full Text | References | PDF (1.2 MB) | EPUB
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Article
A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care
Shufeng Yi, Fan Yang, Cunle Jie & Guiqin Zhang
Pages: 3438-3447
Published online: 14 Aug 2019
AbstractforA novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care | Full Text | References | PDF (1.9 MB) | EPUB
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Research Article

Article
Oxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel
Xiaona An, Xiaotong Sun, Xiaomei Yang, Dejie Liu, Yonghao Hou, Hongli Chen & Jianbo Wu
Pages: 3448-3455
Published online: 14 Aug 2019
AbstractforOxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel | Full Text | References | PDF (1.2 MB) | EPUB
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Article

Article
Hyaluronic acid-modified selenium nanoparticles for enhancing the therapeutic efficacy of paclitaxel in lung cancer therapy
Jianjun Zou, Shan Su, Zhuohong Chen, Feng Liang, Yunyun Zeng, Wenchang Cen, Xianlan Zhang, Yu Xia & Donglan Huang
Pages: 3456-3464
Published online: 30 Aug 2019
AbstractforHyaluronic acid-modified selenium nanoparticles for enhancing the therapeutic efficacy of paclitaxel in lung cancer therapy | Full Text | References | PDF (1.4 MB) | EPUB
  • 4149 Views
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Article
Inhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer
Hong-Jun Xie, Jing Zhao, DongZhi Zhuo-Ma, NorBu Zhan-Dui, Aga Er-Bu & Tashi Tsering
Pages: 3465-3477
Published online: 21 Aug 2019
AbstractforInhibiting tumour metastasis by DQA modified paclitaxel plus ligustrazine micelles in treatment of non-small-cell lung cancer | Full Text | References | PDF (2.4 MB) | EPUB
  • 1605 Views
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Article
Silencing circular ANRIL protects HK-2 cells from lipopolysaccharide-induced inflammatory injury through up-regulating microRNA-9
Wenyan Deng, Kai Chen, Shuxia Liu & Yingying Wang
Pages: 3478-3484
Published online: 21 Aug 2019
AbstractforSilencing circular ANRIL protects HK-2 cells from lipopolysaccharide-induced inflammatory injury through up-regulating microRNA-9 | Full Text | References | PDF (996 KB) | EPUB
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Article
Functionalized selenium nanoparticles enhance the anti-EV71 activity of oseltamivir in human astrocytoma cell model
Jiayu Zhong, Yu Xia, Liang Hua, Xiaomin Liu, Misi Xiao, Tiantian Xu, Bing Zhu & Hong Cao
Pages: 3485-3491
Published online: 19 Aug 2019
AbstractforFunctionalized selenium nanoparticles enhance the anti-EV71 activity of oseltamivir in human astrocytoma cell model | Full Text | References | PDF (1.1 MB) | EPUB
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Research Article

Article
Long non-coding RNA UCA1 relieves cardiomyocytes H9c2 injury aroused by oxygen-glucose deprivation via declining miR-122
Zaiwei Zhang, Hu Li, Zhiyuan Cui, Zhongxing Zhou, Shasha Chen, Jie Ma, Lijuan Hou, Xiaoyu Pan & Qiaoju Li
Pages: 3492-3499
Published online: 21 Aug 2019
AbstractforLong non-coding RNA UCA1 relieves cardiomyocytes H9c2 injury aroused by oxygen-glucose deprivation via declining miR-122 | Full Text | References | PDF (1.1 MB) | EPUB
  • 1995 Views
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Article

Article
RETRACTED ARTICLE: Anti-gastric cancer effect of Salidroside through elevating miR-99a expression
Lin Yang, Yanan Yu, Qi Zhang, Xiaoyu Li, Cuiping Zhang, Tao Mao, Siliang Liu & Zibin Tian
Pages: 3500-3510
Published online: 21 Aug 2019
AbstractforRETRACTED ARTICLE: Anti-gastric cancer effect of Salidroside through elevating miR-99a expression | PDF (2.3 MB)
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Retracted Article

Article
RETRACTED ARTICLE: LncRNA TUG1 protects against cardiomyocyte ischaemia reperfusion injury by inhibiting HMGB1
Hanyu Shi, Zhenhua Dong & Haiqing Gao
Pages: 3511-3516
Published online: 21 Aug 2019
AbstractforRETRACTED ARTICLE: LncRNA TUG1 protects against cardiomyocyte ischaemia reperfusion injury by inhibiting HMGB1 | PDF (1.7 MB)
  • 1760 Views
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Article

Article
Synthesis of sevoflurane loaded reduced graphene oxide nanoparticles system for neuroprotective effects for preconditioning against focal cerebral ischaemia
Qinjuan Wu, Mingfeng Qin & Kun Zhang
Pages: 3517-3523
Published online: 27 Aug 2019
AbstractforSynthesis of sevoflurane loaded reduced graphene oxide nanoparticles system for neuroprotective effects for preconditioning against focal cerebral ischaemia | Full Text | References | PDF (855.8 KB) | EPUB
  • 1244 Views
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Review

Review
Tailoring synthetic polymeric biomaterials towards nerve tissue engineering: a review
Hamed Amani, Hanif Kazerooni, Hossein Hassanpoor, Abolfazl Akbarzadeh & Hamidreza Pazoki-Toroudi
Pages: 3524-3539
Published online: 22 Aug 2019
AbstractforTailoring synthetic polymeric biomaterials towards nerve tissue engineering: a review | Full Text | References | PDF (2.4 MB) | EPUB
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Research Article

Article
Sublingual immunotherapy of atopic dermatitis in mite-sensitized patients: a multi-centre, randomized, double-blind, placebo-controlled study
Lunfei Liu, Jisu Chen, Jinhua Xu, Qinping Yang, Chaoying Gu, Chunya Ni, Linfeng Li, Xueyan Lu, Zhirong Yao, Jianfeng Tao, Yifeng Guo, Hong Fang, Yingguo Ding, Qihong Qian, Naihui Zhou, Miaomiao Wang, Danqi Deng, Hong Xie, Shenqiu Li, Yongchu Huang, Naiqing Zhao & Min Zheng
Pages: 3540-3547
Published online: 22 Aug 2019
AbstractforSublingual immunotherapy of atopic dermatitis in mite-sensitized patients: a multi-centre, randomized, double-blind, placebo-controlled study | Full Text | References | PDF (945.4 KB) | EPUB
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Original Articles

Article
Zinc oxide nanoparticles synthesized from Allium cepa prevents UVB radiation mediated inflammation in human epidermal keratinocytes (HaCaT cells)
Fenglian Wu, Yanxin Chen, Guoliang Li, Donglai Zhu, Lianying Wang & Jiaxin Wang
Pages: 3548-3558
Published online: 28 Aug 2019
AbstractforZinc oxide nanoparticles synthesized from Allium cepa prevents UVB radiation mediated inflammation in human epidermal keratinocytes (HaCaT cells) | Full Text | References | PDF (1.3 MB) | EPUB
  • 2747 Views
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Research Article

Article
The study of mechanism of miR-34c-5p targeting FLOT2 to regulate proliferation, migration and invasion of osteosarcoma cells
Yuqiang Wang, Xiaohua Wang, Jiqiang Tang, Xuetao Su & YaJun Miao
Pages: 3559-3568
Published online: 26 Aug 2019
AbstractforThe study of mechanism of miR-34c-5p targeting FLOT2 to regulate proliferation, migration and invasion of osteosarcoma cells | Full Text | References | PDF (1.7 MB) | EPUB
  • 1476 Views
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Article
GPR39 agonist TC-G 1008 promotes osteoblast differentiation and mineralization in MC3T3-E1 cells
Xingyu Chai, Wencan Zhang, Bingying Chang, Xianli Feng, Jiang Song, Le Li, Chenxiao Yu, Junyong Zhao & Haipeng Si
Pages: 3569-3576
Published online: 26 Aug 2019
AbstractforGPR39 agonist TC-G 1008 promotes osteoblast differentiation and mineralization in MC3T3-E1 cells | Full Text | References | PDF (1 MB) | EPUB
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Article

Article
Anticarcinogenic potential of gold nanoparticles synthesized from Trichosanthes kirilowii in colon cancer cells through the induction of apoptotic pathway
Xiaodong Han, Xiaojia Jiang, Lanjie Guo, Yongxin Wang, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Zhigang Wang & Dandan Cao
Pages: 3577-3584
Published online: 28 Aug 2019
AbstractforAnticarcinogenic potential of gold nanoparticles synthesized from Trichosanthes kirilowii in colon cancer cells through the induction of apoptotic pathway | Full Text | References | PDF (1.1 MB) | EPUB
  • 2712 Views
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Research Article

Article
Long noncoding RNA DRAIC acts as a microRNA-122 sponge to facilitate nasopharyngeal carcinoma cell proliferation, migration and invasion via regulating SATB1
Bing Liao, Zhi Wang, Yaqiong Zhu, Meiqun Wang & Yuehui Liu
Pages: 3585-3597
Published online: 09 Sep 2019
AbstractforLong noncoding RNA DRAIC acts as a microRNA-122 sponge to facilitate nasopharyngeal carcinoma cell proliferation, migration and invasion via regulating SATB1 | Full Text | References | PDF (2.1 MB) | EPUB
  • 1632 Views
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Article
Application of biological variation and six sigma models to evaluate analytical quality of six HbA1c analyzers and design quality control strategy
Xia Wang, Dongmei Wen, Weijia Wang, Minghuan Suo & Ting Hu
Pages: 3598-3602
Published online: 28 Aug 2019
AbstractforApplication of biological variation and six sigma models to evaluate analytical quality of six HbA1c analyzers and design quality control strategy | Full Text | References | PDF (617.5 KB) | EPUB
  • 2038 Views
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Article
Low intensity pulsed ultrasound promotes the migration of bone marrow- derived mesenchymal stem cells via activating FAK-ERK1/2 signalling pathway
Junlin Chen, Jingwei Jiang, Wei Wang, Juan Qin, Jinyun Chen, Wenzhi Chen & Yan Wang
Pages: 3603-3613
Published online: 30 Aug 2019
AbstractforLow intensity pulsed ultrasound promotes the migration of bone marrow- derived mesenchymal stem cells via activating FAK-ERK1/2 signalling pathway | Full Text | References | PDF (1.8 MB) | EPUB
  • 2872 Views
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Article
Juglanin inhibits IL-1β-induced inflammation in human chondrocytes
Xinxin Chen, Chengyong Zhang, Xiao Wang & Shousong Huo
Pages: 3614-3620
Published online: 30 Aug 2019
AbstractforJuglanin inhibits IL-1β-induced inflammation in human chondrocytes | Full Text | References | PDF (1.2 MB) | EPUB
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Review

Review
A promising cancer diagnosis and treatment strategy: targeted cancer therapy and imaging based on antibody fragment
Xuhong Zhao, Qian Ning, Zhongcheng Mo & Shengsong Tang
Pages: 3621-3630
Published online: 30 Aug 2019
AbstractforA promising cancer diagnosis and treatment strategy: targeted cancer therapy and imaging based on antibody fragment | Full Text | References | PDF (985.1 KB) | EPUB
  • 3089 Views
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Research Article

Article
MiR-463-3p inhibits tibial nerve regeneration via post-transcriptional suppression of SPRR1A
Jun Zhao & Chunfang Wu
Pages: 3631-3637
Published online: 30 Aug 2019
AbstractforMiR-463-3p inhibits tibial nerve regeneration via post-transcriptional suppression of SPRR1A | Full Text | References | PDF (919.3 KB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: The circular RNA hsa-circ-0072309 plays anti-tumour roles by sponging miR-100 through the deactivation of PI3K/AKT and mTOR pathways in the renal carcinoma cell lines
Tao Chen, Shixiu Shao, Wenxian Li, Yong Liu & Yanwei Cao
Pages: 3638-3648
Published online: 28 Aug 2019
AbstractforRETRACTED ARTICLE: The circular RNA hsa-circ-0072309 plays anti-tumour roles by sponging miR-100 through the deactivation of PI3K/AKT and mTOR pathways in the renal carcinoma cell lines | PDF (3 MB)
  • 2164 Views
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Article
RETRACTED ARTICLE: Long noncoding RNA HAGLROS promotes the process of mantle cell lymphoma by regulating miR-100/ATG5 axis and involving in PI3K/AKT/mTOR signal
Guangfu Mu, Qian Liu, Si Wu, Yong Xia & Qing Fang
Pages: 3649-3656
Published online: 09 Sep 2019
AbstractforRETRACTED ARTICLE: Long noncoding RNA HAGLROS promotes the process of mantle cell lymphoma by regulating miR-100/ATG5 axis and involving in PI3K/AKT/mTOR signal | PDF (2.7 MB)
  • 1357 Views
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Research Article

Article
Baicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway
Hailiang Yu, Bin Chen & Qi Ren
Pages: 3657-3663
Published online: 03 Sep 2019
AbstractforBaicalin relieves hypoxia-aroused H9c2 cell apoptosis by activating Nrf2/HO-1-mediated HIF1α/BNIP3 pathway | Full Text | References | PDF (1.1 MB) | EPUB
  • 9955 Views
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Article
OB-RGRP regulates the phosphorylation of JAK2 and STAT3 in primary rat adipocytes
Xiaolin Li, Weihong Shi, Guohui Wu, Xu Qin, Guanqun Wan, Qi Zeng & Yungang Hu
Pages: 3664-3670
Published online: 06 Sep 2019
AbstractforOB-RGRP regulates the phosphorylation of JAK2 and STAT3 in primary rat adipocytes | Full Text | References | PDF (1 MB) | EPUB
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Article

Article
miR-342 suppresses the proliferation and invasion of acute myeloid leukemia by targeting Naa10p
Haiyan Wang, Heng He & Chunyan Yang
Pages: 3671-3676
Published online: 09 Sep 2019
AbstractformiR-342 suppresses the proliferation and invasion of acute myeloid leukemia by targeting Naa10p | Full Text | References | PDF (767.6 KB) | EPUB
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Research Article

Article
Involvement of NF-κB signaling pathway in the regulation of PRKAA1-mediated tumorigenesis in gastric cancer
Yangmei Zhang, Xichang Zhou, Qinglin Zhang, Youwei Zhang, Xiang Wang & Long Cheng
Pages: 3677-3686
Published online: 06 Sep 2019
AbstractforInvolvement of NF-κB signaling pathway in the regulation of PRKAA1-mediated tumorigenesis in gastric cancer | Full Text | References | PDF (1.7 MB) | EPUB
  • 1913 Views
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Article

Article
PTEN negatively regulates the expression of pro-inflammatory cytokines and chemokines of fibroblast-like synoviocytes in adjuvant-induced arthritis
Xiao-Feng Li, Xin Chen, Jing Bao, Le Xu, Lei Zhang, Cheng Huang, Xiao-Ming Meng & Jun Li
Pages: 3687-3696
Published online: 06 Sep 2019
AbstractforPTEN negatively regulates the expression of pro-inflammatory cytokines and chemokines of fibroblast-like synoviocytes in adjuvant-induced arthritis | Full Text | References | PDF (1.4 MB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: miR-200a-3p plays tumor suppressor roles in gastric cancer cells by targeting KLF12
Changhe Jia, Yanrui Zhang, Yi Xie, Ying Ren, Haihui Zhang, Yinglei Zhou, Ning Gao, Songze Ding & Shuangyin Han
Pages: 3697-3703
Published online: 10 Sep 2019
AbstractforRETRACTED ARTICLE: miR-200a-3p plays tumor suppressor roles in gastric cancer cells by targeting KLF12 | PDF (2 MB)
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Research Article

Article
Cilostazol ameliorates high free fatty acid (FFA)-induced activation of NLRP3 inflammasome in human vascular endothelial cells
Xing Wang, Huiling Huang, Chen Su, Qiaoqing Zhong & Guifu Wu
Pages: 3704-3710
Published online: 13 Sep 2019
AbstractforCilostazol ameliorates high free fatty acid (FFA)-induced activation of NLRP3 inflammasome in human vascular endothelial cells | Full Text | References | PDF (882.5 KB) | EPUB
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Article
Downregulation of miR-146a promotes tumorigenesis of cervical cancer stem cells via VEGF/CDC42/PAK1 signaling pathway
Zhihong Dong, Chunxia Yu, Kuerban Rezhiya, Aier Gulijiahan & Xinling Wang
Pages: 3711-3719
Published online: 16 Sep 2019
AbstractforDownregulation of miR-146a promotes tumorigenesis of cervical cancer stem cells via VEGF/CDC42/PAK1 signaling pathway | Full Text | References | PDF (1.2 MB) | EPUB
  • 2003 Views
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Article
Matrine derivate MASM protects murine MC3T3-E1 osteoblastic cells against dexamethasone-induced apoptosis via the regulation of USP14/p53
Panyu Zhou, Demeng Xia, Yang Wang, Hongdi Lv, Ziqin Wang, Malcolm Xing, Qingjie Zhao & Shuogui Xu
Pages: 3720-3728
Published online: 16 Sep 2019
AbstractforMatrine derivate MASM protects murine MC3T3-E1 osteoblastic cells against dexamethasone-induced apoptosis via the regulation of USP14/p53 | Full Text | References | PDF (1.5 MB) | EPUB
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Article

Article
Effect of miR-21 on apoptosis in hepatoblastoma cell through activating ASPP2/p38 signaling pathway in vitro and in vivo
Lili Liu, Likun Wang, Xidong Li, Ping Tian, Hao Xu, Zenglian Li & Enqin Liu
Pages: 3729-3736
Published online: 19 Sep 2019
AbstractforEffect of miR-21 on apoptosis in hepatoblastoma cell through activating ASPP2/p38 signaling pathway in vitro and in vivo | Full Text | References | PDF (1.1 MB) | EPUB
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Research Article

Article
LINC01354 enhances the proliferation and invasion of lung cancer cells by regulating miR-340-5p/ATF1 signaling pathway
Gaojie Yang, Chongyi Yang, Yahui She, Zuojun Shen & Peng Gao
Pages: 3737-3744
Published online: 20 Sep 2019
AbstractforLINC01354 enhances the proliferation and invasion of lung cancer cells by regulating miR-340-5p/ATF1 signaling pathway | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Osteopontin promotes rat hepatocyte proliferation both in vitro and in vivo
Gaiping Wang, Peipei Chu, Meng Chen, Liya Cheng, Congcong Zhao, Shasha Chen, Xiaofang Li, Ganggang Yang & Cuifang Chang
Pages: 3745-3757
Published online: 22 Sep 2019
AbstractforOsteopontin promotes rat hepatocyte proliferation both in vitro and in vivo | Full Text | References | PDF (1.8 MB) | EPUB
  • 2819 Views
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Article
CTRP3 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells
Jian Zhang & Jing He
Pages: 3758-3764
Published online: 26 Sep 2019
AbstractforCTRP3 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells | Full Text | References | PDF (895.4 KB) | EPUB
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Article
Activation of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the development of breast cancer via activating CXCL8 and NF-kB pathway
Tongbo Yi, Xiaoqing Zhou, Kai Sang, Xuchen Huang, Jian Zhou & Lan Ge
Pages: 3765-3773
Published online: 26 Sep 2019
AbstractforActivation of lncRNA lnc-SLC4A1-1 induced by H3K27 acetylation promotes the development of breast cancer via activating CXCL8 and NF-kB pathway | Full Text | References | PDF (1.3 MB) | EPUB
  • 3136 Views
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Article
Uric acid and sphingomyelin enhance autophagy in iPS cell-originated cardiomyocytes through lncRNA MEG3/miR-7-5p/EGFR axis
Yinyin Cao, Junxiang Wen, Yang Li, Weicheng Chen, Yao Wu, Jian Li & Guoying Huang
Pages: 3774-3785
Published online: 27 Sep 2019
AbstractforUric acid and sphingomyelin enhance autophagy in iPS cell-originated cardiomyocytes through lncRNA MEG3/miR-7-5p/EGFR axis | Full Text | References | PDF (1.7 MB) | EPUB
  • 3297 Views
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Article
PLCG2 promotes hepatocyte proliferation in vitro via NF-κB and ERK pathway by targeting bcl2, myc and ccnd1
Donghui Ma, Fang Lian & Xiaobai Wang
Pages: 3786-3792
Published online: 24 Sep 2019
AbstractforPLCG2 promotes hepatocyte proliferation in vitro via NF-κB and ERK pathway by targeting bcl2, myc and ccnd1 | Full Text | References | PDF (846.6 KB) | EPUB
  • 2373 Views
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Article
Macrophage-derived exosomes accelerate wound healing through their anti-inflammation effects in a diabetic rat model
Mengdie Li, Tao Wang, He Tian, Guohua Wei, Liang Zhao & Yijie Shi
Pages: 3793-3803
Published online: 26 Sep 2019
AbstractforMacrophage-derived exosomes accelerate wound healing through their anti-inflammation effects in a diabetic rat model | Full Text | References | PDF (2.2 MB) | EPUB
  • 8414 Views
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Article
Mesenchymal stem cells derived exosomal miR-323-3p promotes proliferation and inhibits apoptosis of cumulus cells in polycystic ovary syndrome (PCOS)
Yinghui Zhao, Mei Tao, Meiling Wei, Shengye Du, Hongping Wang & Xiaohong Wang
Pages: 3804-3813
Published online: 24 Sep 2019
AbstractforMesenchymal stem cells derived exosomal miR-323-3p promotes proliferation and inhibits apoptosis of cumulus cells in polycystic ovary syndrome (PCOS) | Full Text | References | PDF (1.3 MB) | EPUB
  • 4976 Views
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Article
Association of TP73-AS1 gene polymorphisms with the risk and survival of gastric cancer in a Chinese Han Population
Wangwang Chen, Jian Xiao, Liang Shi, Linling Lin, Mingkun Jiang, Yugang Ge, Zengliang Li, Hao Fan, Li Yang & Zekuan Xu
Pages: 3814-3822
Published online: 24 Sep 2019
AbstractforAssociation of TP73-AS1 gene polymorphisms with the risk and survival of gastric cancer in a Chinese Han Population | Full Text | References | PDF (963.4 KB) | EPUB
  • 1580 Views
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Article
DPP-4 inhibitor anagliptin protects against hypoxia-induced cytotoxicity in cardiac H9C2 cells
Yunxiang Ma, Junkai Wang, Changhua Wang, Qiong Zhang, Yannan Xu, Huajin Liu, Xia Xiang & Jiangwei Ma
Pages: 3823-3831
Published online: 26 Sep 2019
AbstractforDPP-4 inhibitor anagliptin protects against hypoxia-induced cytotoxicity in cardiac H9C2 cells | Full Text | References | PDF (1.2 MB) | EPUB
  • 2082 Views
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Article
Facile green synthesis of bismuth sulfide radiosensitizer via biomineralization of albumin natural molecule for chemoradiation therapy aim
Hamed Nosrati, Fatemeh Abhari, Jalil Charmi, Mohammad Rahmati, Behrooz Johari, Sedigheh Azizi, Hamed Rezaeejam & Hossein Danafar
Pages: 3832-3838
Published online: 26 Sep 2019
AbstractforFacile green synthesis of bismuth sulfide radiosensitizer via biomineralization of albumin natural molecule for chemoradiation therapy aim | Full Text | References | PDF (1.1 MB) | EPUB
  • 1993 Views
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Article
Sinomenine restrains breast cancer cells proliferation, migration and invasion via modulation of miR-29/PDCD-4 axis
Guanglei Gao, Xiaolin Liang & Wenyan Ma
Pages: 3839-3846
Published online: 26 Sep 2019
AbstractforSinomenine restrains breast cancer cells proliferation, migration and invasion via modulation of miR-29/PDCD-4 axis | Full Text | References | PDF (1.1 MB) | EPUB
  • 2135 Views
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Article
Knockdown of lncRNA Gm11974 protect against cerebral ischemic reperfusion through miR-766-3p/NR3C2 axis
Jiangping Cai, Shina Shangguan, Guoqian Li, Yazhen Cai, Yuanjie Chen, Gaoting Ma, Zhongrong Miao, Lian Liu & Yiming Deng
Pages: 3847-3853
Published online: 26 Sep 2019
AbstractforKnockdown of lncRNA Gm11974 protect against cerebral ischemic reperfusion through miR-766-3p/NR3C2 axis | Full Text | References | PDF (985.7 KB) | EPUB
  • 2186 Views
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Article
Upregulation of lncRNA H19 promotes nasopharyngeal carcinoma proliferation and metastasis in let-7 dependent manner
Yujie Zhang, Ronghua Zhu, Jia Wang, Zheqing Cui, Ying Wang & Yulin Zhao
Pages: 3854-3861
Published online: 26 Sep 2019
AbstractforUpregulation of lncRNA H19 promotes nasopharyngeal carcinoma proliferation and metastasis in let-7 dependent manner | Full Text | References | PDF (1 MB) | EPUB
  • 1584 Views
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Article
ZBTB20 promotes cell migration and invasion of gastric cancer by inhibiting IκBα to induce NF-κB activation
Yangmei Zhang, Xichang Zhou, ManMan Zhang, Long Cheng, Youwei Zhang & Xiang Wang
Pages: 3862-3872
Published online: 26 Sep 2019
AbstractforZBTB20 promotes cell migration and invasion of gastric cancer by inhibiting IκBα to induce NF-κB activation | Full Text | References | PDF (2.1 MB) | EPUB
  • 2343 Views
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Article
An integrated analysis of the circRNA–miRNA–mRNA network reveals novel insights into potential mechanisms of cell proliferation during liver regeneration
Gaiping Wang, Xueqiang Guo, Liya Cheng, Peipei Chu, Meng Chen, Yanhui Chen & Cuifang Chang
Pages: 3873-3884
Published online: 28 Sep 2019
AbstractforAn integrated analysis of the circRNA–miRNA–mRNA network reveals novel insights into potential mechanisms of cell proliferation during liver regeneration | Full Text | References | PDF (1.5 MB) | EPUB
  • 2855 Views
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Retracted Article

Article
RETRACTED ARTICLE: MicroRNA-3194-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by decreasing Wnt/β-catenin signaling through targeting BCL9
Bowen Yao, Yazhao Li, Liang Wang, Tianxiang Chen, Yongshen Niu, Qingguang Liu & Zhikui Liu
Pages: 3885-3895
Published online: 27 Sep 2019
AbstractforRETRACTED ARTICLE: MicroRNA-3194-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by decreasing Wnt/β-catenin signaling through targeting BCL9 | PDF (5.1 MB)
  • 1798 Views
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Research Article

Article
Long non-coding RNA LINC00473 promotes glioma cells proliferation and invasion by impairing miR-637/CDK6 axis
Qiansheng Zhang, Genwei Wang, Liping Xu, Zhiqiang Yao & Laijun Song
Pages: 3896-3903
Published online: 27 Sep 2019
AbstractforLong non-coding RNA LINC00473 promotes glioma cells proliferation and invasion by impairing miR-637/CDK6 axis | Full Text | References | PDF (1.3 MB) | EPUB
  • 1390 Views
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Article
Junduqing extractive promotes the apoptosis of nasopharyngeal carcinoma cells through down-regulating Mcl-1 and Bcl-xL and up-regulating Caspase-3, Caspase-8 and Caspase-9
Weiguo Zhao, Lei Tang, Shan Gao, Ling Xin, Haiyong Zhang & Yunjing Li
Pages: 3904-3912
Published online: 29 Sep 2019
AbstractforJunduqing extractive promotes the apoptosis of nasopharyngeal carcinoma cells through down-regulating Mcl-1 and Bcl-xL and up-regulating Caspase-3, Caspase-8 and Caspase-9 | Full Text | References | PDF (1.6 MB) | EPUB
  • 1391 Views
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Retracted Article

Article
RETRACTED ARTICLE: The anti-osteosarcoma property of ailanthone through regulation of miR-126/VEGF-A axis
Daliang Kong, Boda Ying, Jinrui Zhang & Hongliang Ying
Pages: 3913-3919
Published online: 01 Oct 2019
AbstractforRETRACTED ARTICLE: The anti-osteosarcoma property of ailanthone through regulation of miR-126/VEGF-A axis | PDF (2.6 MB)
  • 1045 Views
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Research Article

Article
Circular RNA ADAM9 facilitates the malignant behaviours of pancreatic cancer by sponging miR-217 and upregulating PRSS3 expression
Chenju Xing, Hua Ye, Weiwei Wang, Miaomiao Sun, Jianying Zhang, Zhihua Zhao & Guozhong Jiang
Pages: 3920-3928
Published online: 06 Dec 2019
AbstractforCircular RNA ADAM9 facilitates the malignant behaviours of pancreatic cancer by sponging miR-217 and upregulating PRSS3 expression | Full Text | References | PDF (1.6 MB) | EPUB
  • 2407 Views
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Article
Taraxasterol from Taraxacum prevents concanavalin A-induced acute hepatic injury in mice via modulating TLRs/NF-κB and Bax/Bc1-2 signalling pathways
Rui Sang, Yifan Yu, Bingjie Ge, Lu Xu, Zheng Wang & Xuemei Zhang
Pages: 3929-3937
Published online: 01 Oct 2019
AbstractforTaraxasterol from Taraxacum prevents concanavalin A-induced acute hepatic injury in mice via modulating TLRs/NF-κB and Bax/Bc1-2 signalling pathways | Full Text | References | PDF (1.3 MB) | EPUB
  • 2502 Views
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Retracted Article

Article
RETRACTED ARTICLE: Lentinan protects cardiomyocytes against hypoxia-induced injury by regulation of microRNA-22/Sirt1
Shaohui Zhang & Yongliang Zhao
Pages: 3938-3946
Published online: 04 Oct 2019
AbstractforRETRACTED ARTICLE: Lentinan protects cardiomyocytes against hypoxia-induced injury by regulation of microRNA-22/Sirt1 | PDF (2.7 MB)
  • 1436 Views
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Research Article

Article
Notoginsenoside R1 alleviates high glucose-evoked damage in RSC96 cells through down-regulation of miR-503
Weiwei Wang, Yan Hao & Feng Li
Pages: 3947-3954
Published online: 04 Oct 2019
AbstractforNotoginsenoside R1 alleviates high glucose-evoked damage in RSC96 cells through down-regulation of miR-503 | Full Text | References | PDF (1.1 MB) | EPUB
  • 2365 Views
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Retracted Article

Article
RETRACTED ARTICLE: Belinostat suppresses cell proliferation by inactivating Wnt/β-catenin pathway and promotes apoptosis through regulating PKC pathway in breast cancer
Pengwei Lu, Yuanting Gu, Lin Li, Fang Wang, Xue Yang & Yunqing Yang
Pages: 3955-3960
Published online: 01 Oct 2019
AbstractforRETRACTED ARTICLE: Belinostat suppresses cell proliferation by inactivating Wnt/β-catenin pathway and promotes apoptosis through regulating PKC pathway in breast cancer | PDF (1.5 MB)
  • 1532 Views
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Research Article

Article
The interaction between self – assembling peptides and emodin and the controlled release of emodin from in-situ hydrogel
Weipeng Wei, Cui Meng, Yuhe Wang, Yongsheng Huang, Wenbin Du, Hongfang Li, Yanfei Liu, Hong Song & Fushan Tang
Pages: 3961-3975
Published online: 07 Oct 2019
AbstractforThe interaction between self – assembling peptides and emodin and the controlled release of emodin from in-situ hydrogel | Full Text | References | PDF (2.5 MB) | EPUB
  • 2204 Views
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Article
Exosomal miR-320d derived from adipose tissue-derived MSCs inhibits apoptosis in cardiomyocytes with atrial fibrillation (AF)
Lina Liu, Haoran Zhang, Hongyu Mao, Xiaohong Li & Yamin Hu
Pages: 3976-3984
Published online: 08 Oct 2019
AbstractforExosomal miR-320d derived from adipose tissue-derived MSCs inhibits apoptosis in cardiomyocytes with atrial fibrillation (AF) | Full Text | References | PDF (1.3 MB) | EPUB
  • 2916 Views
  • 43 CrossRef citations
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Article
GAS5, a FoxO1-actived long noncoding RNA, promotes propofol-induced oral squamous cell carcinoma apoptosis by regulating the miR-1297-GSK3β axis
Chengshun Gao, Chunmei Ren, Zhongxi Liu, Li Zhang, Ranran Tang & Xiaojie Li
Pages: 3985-3993
Published online: 04 Oct 2019
AbstractforGAS5, a FoxO1-actived long noncoding RNA, promotes propofol-induced oral squamous cell carcinoma apoptosis by regulating the miR-1297-GSK3β axis | Full Text | References | PDF (1.6 MB) | EPUB
  • 2466 Views
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Retracted Article

Article
RETRACTED ARTICLE: Lycium barbarum polysaccharide alleviates oxygen glucose deprivation-induced PC-12 cells damage by up-regulating miR-24
Shiqing Song, Faliang Lin, Pengyan Zhu, Changyan Wu, Shuling Zhao, Qiao Han & Xiaomei Li
Pages: 3994-4000
Published online: 07 Oct 2019
AbstractforRETRACTED ARTICLE: Lycium barbarum polysaccharide alleviates oxygen glucose deprivation-induced PC-12 cells damage by up-regulating miR-24 | PDF (2.1 MB)
  • 1552 Views
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Research Article

Article
Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway
Tianqi Li, Yudi Xiong, Qingqing Wang, Fengxia Chen, Yangyang Zeng, Xiaoyan Yu, Yuan Wang, Fuxiang Zhou & Yunfeng Zhou
Pages: 4001-4011
Published online: 07 Oct 2019
AbstractforRibociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway | Full Text | References | PDF (1.9 MB) | EPUB
  • 4415 Views
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Article
Anticancer activity of green synthesised gold nanoparticles from Marsdenia tenacissima inhibits A549 cell proliferation through the apoptotic pathway
Butong Sun, Nanjun Hu, Leng Han, Yanan Pi, Yu Gao & Kang Chen
Pages: 4012-4019
Published online: 08 Oct 2019
AbstractforAnticancer activity of green synthesised gold nanoparticles from Marsdenia tenacissima inhibits A549 cell proliferation through the apoptotic pathway | Full Text | References | PDF (1.2 MB) | EPUB
  • 5830 Views
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Article
Poly-l-lactic acid scaffold incorporated chitosan-coated mesoporous silica nanoparticles as pH-sensitive composite for enhanced osteogenic differentiation of human adipose tissue stem cells by dexamethasone delivery
Mohammad Porgham Daryasari, Mehdi Dusti Telgerd, Mohammad Hossein Karami, Ali Zandi-Karimi, Hamid Akbarijavar, Mehdi Khoobi, Ehsan Seyedjafari, Gebremariam Birhanu, Pegah Khosravian & Fatemeh SadatMahdavi
Pages: 4020-4029
Published online: 09 Oct 2019
AbstractforPoly-l-lactic acid scaffold incorporated chitosan-coated mesoporous silica nanoparticles as pH-sensitive composite for enhanced osteogenic differentiation of human adipose tissue stem cells by dexamethasone delivery | Full Text | References | PDF (1.6 MB) | EPUB
  • 3117 Views
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Article
Protective functions of salvianolic acid B in PC-12 cells against hydrogen peroxide-triggered damage by mediation of microRNA-26a
Niansheng Liu & Mingfu Fan
Pages: 4030-4037
Published online: 11 Oct 2019
AbstractforProtective functions of salvianolic acid B in PC-12 cells against hydrogen peroxide-triggered damage by mediation of microRNA-26a | Full Text | References | PDF (1.2 MB) | EPUB
  • 1493 Views
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Article
Circ_0026344 restrains metastasis of human colorectal cancer cells via miR-183
Tao Shen, Xianshuo Cheng, Xin Liu, Cuifeng Xia, Hongtao Zhang, Dingguo Pan, Xuan Zhang & Yunfeng Li
Pages: 4038-4045
Published online: 14 Oct 2019
AbstractforCirc_0026344 restrains metastasis of human colorectal cancer cells via miR-183 | Full Text | References | PDF (1.1 MB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: Lycium barbarum polysaccharide alleviates IL-1β-evoked chondrogenic ATDC5 cell inflammatory injury through mediation of microRNA-124
Huawei Ni, Guoxiu Wang, Yu Xu, Xiaomin Gu, Chengzhang Sun & Haibo Li
Pages: 4046-4052
Published online: 14 Oct 2019
AbstractforRETRACTED ARTICLE: Lycium barbarum polysaccharide alleviates IL-1β-evoked chondrogenic ATDC5 cell inflammatory injury through mediation of microRNA-124 | PDF (2.4 MB)
  • 1379 Views
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Research Article

Article
Efficacy of nanodiamond–doxorubicin complexes on human breast adenocarcinoma cell lines
Kitsakorn Locharoenrat
Pages: 4053-4058
Published online: 14 Oct 2019
AbstractforEfficacy of nanodiamond–doxorubicin complexes on human breast adenocarcinoma cell lines | Full Text | References | PDF (1 MB) | EPUB
  • 2478 Views
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Article
Silibinin declines blue light-induced apoptosis and inflammation through MEK/ERK/CREB of retinal ganglion cells
Ying Shen, Haixia Zhao, Zhaoge Wang, Wenying Guan, Xin Kang, Xue Tai & Yaru Sun
Pages: 4059-4065
Published online: 20 Oct 2019
AbstractforSilibinin declines blue light-induced apoptosis and inflammation through MEK/ERK/CREB of retinal ganglion cells | Full Text | References | PDF (856.5 KB) | EPUB
  • 2565 Views
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Retracted Article

Review
RETRACTED ARTICLE: Nanoscale drug delivery strategies for therapy of ovarian cancer: conventional vs targeted
Swati Gupta, Yashwant Pathak, Manish K. Gupta & Suresh P. Vyas
Pages: 4066-4088
Published online: 18 Oct 2019
AbstractforRETRACTED ARTICLE: Nanoscale drug delivery strategies for therapy of ovarian cancer: conventional vs targeted | PDF (3.4 MB)
  • 4081 Views
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Article
RETRACTED ARTICLE: Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF
Gang Wang, Ping Wang, Xiaojun Yan & Jing Liu
Pages: 4089-4096
Published online: 21 Oct 2019
AbstractforRETRACTED ARTICLE: Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF | PDF (3 MB)
  • 920 Views
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Research Article

Article
Characterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles
Fan Li, Yuqin Wen, Yan Zhang, Kangyu Zheng, Junfeng Ban, Qingchun Xie, Yifeng Wen, Qing Liu, Fohua Chen, Zhenjie Mo, Lizhong Liu, Yanzhong Chen & Zhufen Lu
Pages: 4097-4108
Published online: 30 Oct 2019
AbstractforCharacterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles | Full Text | References | PDF (1.6 MB) | EPUB
  • 3305 Views
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Correction

Correction
Correction
Page: 4109
Published online: 30 Oct 2019
CitationforCorrection | Full Text | PDF (141 KB) | EPUB
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Research Article

Article
MiR-199a-5p regulates rat liver regeneration and hepatocyte proliferation by targeting TNF-α TNFR1/TRADD/CASPASE8/CASPASE3 signalling pathway
Chunyan Zhang, Bingyu Ye, Jiaojiao Wei, Qiwen Wang, Cunshuan Xu & Guoying Yu
Pages: 4110-4118
Published online: 04 Nov 2019
AbstractforMiR-199a-5p regulates rat liver regeneration and hepatocyte proliferation by targeting TNF-α TNFR1/TRADD/CASPASE8/CASPASE3 signalling pathway | Full Text | References | PDF (1.3 MB) | EPUB
  • 2058 Views
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Correction

Correction
Correction
Page: 4119
Published online: 04 Nov 2019
CitationforCorrection | Full Text | PDF (188.9 KB) | EPUB
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Research Article

Article
Circ-PRMT5 promotes gastric cancer progression by sponging miR-145 and miR-1304 to upregulate MYC
Wenbo Du, Ding Li, Xiaomin Guo, Ping Li, Xin Li, Shuping Tong, Junhui Tong, Lihua Kuang & Daoming Liang
Pages: 4120-4130
Published online: 08 Nov 2019
AbstractforCirc-PRMT5 promotes gastric cancer progression by sponging miR-145 and miR-1304 to upregulate MYC | Full Text | References | PDF (1.8 MB) | EPUB
  • 2598 Views
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Article
Sinomenine hydrochloride exerts antitumor outcome in ovarian cancer cells by inhibition of long non-coding RNA HOST2 expression
Yuting Xu, Tao Jiang, Changhe Wang & Fei Wang
Pages: 4131-4138
Published online: 08 Nov 2019
AbstractforSinomenine hydrochloride exerts antitumor outcome in ovarian cancer cells by inhibition of long non-coding RNA HOST2 expression | Full Text | References | PDF (1 MB) | EPUB
  • 1368 Views
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Review

Review
Clinicopathological and prognostic significance of epithelial cell transforming sequence 2 expression in cancers: a systematic review and meta-analysis
Bin Li, Jun-Ping Lin, Zheng Li, Ci Yin, Jian-Bao Yang & Yu-Qi Meng
Pages: 4139-4148
Published online: 07 Nov 2019
AbstractforClinicopathological and prognostic significance of epithelial cell transforming sequence 2 expression in cancers: a systematic review and meta-analysis | Full Text | References | PDF (1.5 MB) | EPUB
  • 1078 Views
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Review
The role of myeloid-derived suppressor cells in the pathogenesis of rheumatoid arthritis; anti- or pro-inflammatory cells?
Misagh Rajabinejad, Farhad Salari, Ali Gorgin Karaji & Alireza Rezaiemanesh
Pages: 4149-4158
Published online: 07 Nov 2019
AbstractforThe role of myeloid-derived suppressor cells in the pathogenesis of rheumatoid arthritis; anti- or pro-inflammatory cells? | Full Text | References | PDF (1.6 MB) | EPUB
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Retracted Article

Article
RETRACTED ARTICLE: Effect of miR-181a-3p on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting BMP10
GuiLu Tao, Ping Mao, HaoNan Guan, MinFei Jiang, Tongbin Chu, CunDi Zhong & JiaZheng Liu
Pages: 4159-4164
Published online: 12 Nov 2019
AbstractforRETRACTED ARTICLE: Effect of miR-181a-3p on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting BMP10 | PDF (1.6 MB)
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Research Article

Article
Protective mechanism of GPR30 agonist G1 against ultraviolet B-induced injury in epidermal stem cells
Yaqin Zhang, Li Li, Yangchun Xu, Xiaoli Zhao & Fuqiu Li
Pages: 4165-4171
Published online: 12 Nov 2019
AbstractforProtective mechanism of GPR30 agonist G1 against ultraviolet B-induced injury in epidermal stem cells | Full Text | References | PDF (965.9 KB) | EPUB
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Article
Astragaloside-IV protects H9C2(2-1) cardiomyocytes from high glucose-induced injury via miR-34a-mediated autophagy pathway
Yaobin Zhu, Xin Qian, Jingjing Li, Xing Lin, Jiewei Luo, Jianbin Huang & Zhao Jin
Pages: 4172-4181
Published online: 12 Nov 2019
AbstractforAstragaloside-IV protects H9C2(2-1) cardiomyocytes from high glucose-induced injury via miR-34a-mediated autophagy pathway | Full Text | References | PDF (1.3 MB) | EPUB
  • 3459 Views
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Article
Anti-tumour effects of a xenogeneic fibroblast activation protein-based whole cell tumour vaccine in murine tumour models
Meihua Chen, Guangchao Xu, Ming Fan, Hongyuan Jia, Ling Xiao & Jinyi Lang
Pages: 4182-4193
Published online: 14 Nov 2019
AbstractforAnti-tumour effects of a xenogeneic fibroblast activation protein-based whole cell tumour vaccine in murine tumour models | Full Text | References | PDF (3.2 MB) | EPUB
  • 1940 Views
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Article
Clinical efficacy and safety of anti-PD-1/PD-L1 treatments in non-small cell lung cancer (NSCLC)
Tian Zeng, Qin Qin, Zhiheng Bian & Jianjun Li
Pages: 4194-4201
Published online: 12 Nov 2019
AbstractforClinical efficacy and safety of anti-PD-1/PD-L1 treatments in non-small cell lung cancer (NSCLC) | Full Text | References | PDF (1.1 MB) | EPUB
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Article
Protective effects of phenformin on zebrafish embryonic neurodevelopmental toxicity induced by X-ray radiation
Lu Gan, Menghuan Guo, Jing Si, Jinhua Zhang, Zhiyuan Liu, Jin Zhao, Fang Wang, Junfang Yan, Hongyan Li & Hong Zhang
Pages: 4202-4210
Published online: 12 Nov 2019
AbstractforProtective effects of phenformin on zebrafish embryonic neurodevelopmental toxicity induced by X-ray radiation | Full Text | References | PDF (1.1 MB) | EPUB
  • 1843 Views
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Article
Co-encapsulation of magnetic Fe3O4 nanoparticles and doxorubicin into biocompatible PLGA-PEG nanocarriers for early detection and treatment of tumours
Chenghua Liang, Nan Li, Zikai Cai, Rongpu Liang, Xiaoming Zheng, Li Deng, Longbao Feng, Rui Guo & Bo Wei
Pages: 4211-4221
Published online: 12 Nov 2019
AbstractforCo-encapsulation of magnetic Fe3O4 nanoparticles and doxorubicin into biocompatible PLGA-PEG nanocarriers for early detection and treatment of tumours | Full Text | References | PDF (1.5 MB) | EPUB
  • 2778 Views
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Review

Review
AuNPs as an important inorganic nanoparticle applied in drug carrier systems
Wen Li, Zhiwen Cao, Rui Liu, Linlin Liu, Hui Li, Xiang Li, Youwen Chen, Cheng Lu & Yuanyan Liu
Pages: 4222-4233
Published online: 12 Nov 2019
AbstractforAuNPs as an important inorganic nanoparticle applied in drug carrier systems | Full Text | References | PDF (1.3 MB) | EPUB
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Research Article

Article
Montelukast promotes mitochondrial biogenesis via CREB/PGC-1α in human bronchial epithelial cells
Huan Wang, Yali Cheng, Ying Liu, Jiang Shi & Zhe Cheng
Pages: 4234-4239
Published online: 14 Nov 2019
AbstractforMontelukast promotes mitochondrial biogenesis via CREB/PGC-1α in human bronchial epithelial cells | Full Text | References | PDF (821.9 KB) | EPUB
  • 2578 Views
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Article
Multiple retrograde tracing methods compatible with 3DISCO clearing
Shuai Han, Dongdong Li, Yuhui Kou, Zhongguo Fu & Xiaofeng Yin
Pages: 4240-4247
Published online: 12 Nov 2019
AbstractforMultiple retrograde tracing methods compatible with 3DISCO clearing | Full Text | References | PDF (1.2 MB) | EPUB
  • 3100 Views
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Article
Preparation of a nanovaccine against Brucella melitensis M16 based on PLGA nanoparticles and oligopolysaccharide antigen
Masoud Maleki, Mojtaba Salouti, Mehdi Shafiee Ardestani & Alireza Talebzadeh
Pages: 4248-4256
Published online: 13 Nov 2019
AbstractforPreparation of a nanovaccine against Brucella melitensis M16 based on PLGA nanoparticles and oligopolysaccharide antigen | Full Text | References | PDF (1.2 MB) | EPUB
  • 1738 Views
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Article
KRas-ERK signalling promotes the onset and maintenance of uveal melanoma through regulating JMJD6-mediated H2A.X phosphorylation at tyrosine 39
Yaping Li, Peng Yu, Ying Zou, Wenrui Cai, Weixuan Sun & Ning Han
Pages: 4257-4265
Published online: 17 Nov 2019
AbstractforKRas-ERK signalling promotes the onset and maintenance of uveal melanoma through regulating JMJD6-mediated H2A.X phosphorylation at tyrosine 39 | Full Text | References | PDF (1.2 MB) | EPUB
  • 1981 Views
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Article
Rapid and quantitative detection of urinary Cyfra21-1 using fluorescent nanosphere-based immunochromatographic test strip for diagnosis and prognostic monitoring of bladder cancer
Qifang Lei, Linlin Zhao, Shuixian Ye, Yue Sun, Fangjie Xie, Hong Zhang, Fangjian Zhou & Song Wu
Pages: 4266-4272
Published online: 15 Nov 2019
AbstractforRapid and quantitative detection of urinary Cyfra21-1 using fluorescent nanosphere-based immunochromatographic test strip for diagnosis and prognostic monitoring of bladder cancer | Full Text | References | PDF (762.1 KB) | EPUB
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Retraction

Retraction
Statement of Retraction
Page: 4273
Published online: 18 Nov 2019
CitationforStatement of Retraction | Full Text | PDF (152.2 KB) | EPUB
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Research Article

Article
Ras-PI3K pathway promotes osteosarcoma progression via regulating VRK1-mediated H2A phosphorylation at threonine 120
Xianlun Xu & Hao Yu
Pages: 4274-4283
Published online: 06 Dec 2019
AbstractforRas-PI3K pathway promotes osteosarcoma progression via regulating VRK1-mediated H2A phosphorylation at threonine 120 | Full Text | References | PDF (1.3 MB) | EPUB
  • 2070 Views
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Article
LINC01518 knockdown inhibits tumorigenicity by suppression of PIK3CA/Akt pathway in oesophageal squamous cell carcinoma
Donghong Zhang, Haifeng Zhang, Xiaolong Wang, Baoli Hu, Feng Zhang, Haitao Wei & Li Li
Pages: 4284-4292
Published online: 06 Dec 2019
AbstractforLINC01518 knockdown inhibits tumorigenicity by suppression of PIK3CA/Akt pathway in oesophageal squamous cell carcinoma | Full Text | References | PDF (1.2 MB) | EPUB
  • 1349 Views
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Article

Article
Cross-linked nanoparticles of silk fibroin with proanthocyanidins as a promising vehicle of indocyanine green for photo-thermal therapy of glioma
De-Li ZhuGe, Li-Fen Wang, Rui Chen, Xin-Ze Li, Zhi-Wei Huang, Qing Yao, Bin Chen, Ying-Zheng Zhao, He-Lin Xu & Jian-Dong Yuan
Pages: 4293-4304
Published online: 06 Dec 2019
AbstractforCross-linked nanoparticles of silk fibroin with proanthocyanidins as a promising vehicle of indocyanine green for photo-thermal therapy of glioma | Full Text | References | PDF (2.3 MB) | EPUB
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