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Emerging Microbes & Infections Volume 10, 2021 - Issue 1
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Research Article

Hepatitis B virus nucleocapsid uncoating: biological consequences and regulation by cellular nucleases

Jin Hua Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USA;b Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
,
Liudi Tanga Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USA;c Microbiology and Immunology Graduate Program, Drexel University College of Medicine, Philadelphia, PA, USAView further author information
,
Junjun Chenga Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USAORCID Iconhttps://orcid.org/0000-0002-3926-1481View further author information
ORCID Icon,
Tianlun Zhoua Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USAView further author information
,
Yuhuan Lib Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaView further author information
,
Jinhong Changa Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USAORCID Iconhttps://orcid.org/0000-0002-6723-494XView further author information
ORCID Icon,
Qiong Zhaoa Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-1491-8205View further author information
ORCID Icon &
Ju-Tao Guoa Department of Experimental Medicine, Baruch S. Blumberg Institute, Doylestown, PA, USACorrespondence[email protected]
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Pages 852-864 | Received 10 Dec 2020, Accepted 14 Apr 2021, Published online: 01 May 2021

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Peng-Hui Zeng & Wen-Jun Yin. (2023) The cGAS/STING signaling pathway: a cross-talk of infection, senescence and tumors. Cell Cycle 22:1, pages 38-56.
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Yu-Chen Chuang, Kuen-Nan Tsai & Jing-Hsiung James Ou. (2022) Pathogenicity and virulence of Hepatitis B virus. Virulence 13:1, pages 258-296.
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Articles from other publishers (12)

Michael Nassal. (2023) How many steps to a feasible mouse model of hepatitis B virus infection?. Hepatology 77:4, pages 1090-1094.
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Xiaoyang Yu, Quanxin Long, Sheng Shen, Zhentao Liu, Jithin Chandran, Junjie Zhang, Hao Ding, Hu Zhang, Dawei Cai, Elena S. Kim, Yufei Huang & Haitao Guo. (2023) Screening of an epigenetic compound library identifies BRD4 as a potential antiviral target for hepatitis B virus covalently closed circular DNA transcription. Antiviral Research 211, pages 105552.
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Megan A. Mendenhall, Xupeng Hong & Jianming Hu. (2023) Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation. Viruses 15:3, pages 642.
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Liudi Tang, Ping An, Qiong Zhao, Cheryl A. Winkler, Jinhong Chang & Ju-Tao Guo. (2023) Heat Shock Protein Family A Member 1 Promotes Intracellular Amplification of Hepatitis B Virus Covalently Closed Circular DNA. Journal of Virology 97:1.
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Cong Xu, Jieqing Fan, Danyang Liu, Aimaier Tuerdi, Juanjuan Chen, Yuning Wei, Yanfang Pan, Huaixin Dang, Xiong Wei, Ashraf Siddig Yousif, Jeysen Yogaratnam, Qiong Zhou, Henri Lichenstein & Tian Xu. (2023) Alpha‐kinase 1 (ALPK1) agonist DF‐006 demonstrates potent efficacy in mouse and primary human hepatocyte (PHH) models of hepatitis B. Hepatology 77:1, pages 275-289.
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Qiong Zhao, Jinhong Chang, Rene Rijnbrand, Angela M. Lam, Michael J. Sofia, Andrea Cuconati & Ju-Tao Guo. (2022) Pregenomic RNA Launch Hepatitis B Virus Replication System Facilitates the Mechanistic Study of Antiviral Agents and Drug-Resistant Variants on Covalently Closed Circular DNA Synthesis. Journal of Virology 96:24.
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Xiaobin Zheng, Yanran Wan, Min Tao, Jiangjiang Yuan, Kun Zhang, Jing Wang, Youjun Zhang, Pei Liang & Qingjun Wu. (2022) Obstructor, a Frankliniella occidentalis protein, promotes transmission of tomato spotted wilt orthotospovirus . Insect Science.
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Ji Xi, Xiuji Cui, Kuancheng Liu, Haitao Liu, Joseph Wang & Jianming Hu. (2022) Region-Specific Hepatitis B Virus Genome Exposure from Nucleocapsid Modulated by Capsid Linker Sequence and Inhibitor: Implications for Uncoating. Journal of Virology 96:8.
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Sandra Huérfano, Vojtech Šroller, Kateřina Bruštíková, Lenka Horníková & Jitka Forstová. (2022) The Interplay between Viruses and Host DNA Sensors. Viruses 14:4, pages 666.
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Yanhua Tang, Hongyan Liang, Ge Zeng, Sheng Shen & Jian Sun. (2022) Advances in new antivirals for chronic hepatitis B. Chinese Medical Journal 135:5, pages 571-583.
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Alexander L. Marchetti, Hu Zhang, Elena S. Kim, Xiaoyang Yu, Sunbok Jang, Mu Wang & Haitao Guo. (2022) Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation. Journal of Virology 96:2.
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Lei Wei & Alexander Ploss. (2021) Mechanism of Hepatitis B Virus cccDNA Formation. Viruses 13:8, pages 1463.
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