Advanced search
Publication Cover
Emerging Microbes & Infections Volume 11, 2022 - Issue 1
Submit an article Journal homepage
5,259
Views
20
CrossRef citations to date
0
Altmetric
Research Article

Outer membrane vesicles-transmitted virulence genes mediate the emergence of new antimicrobial-resistant hypervirulent Klebsiella pneumoniae

Yuneng Huaa Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China;b Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Jingyu Wangb Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Mei Huanga Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Yiyi Huangb Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Ruyi Zhangb Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Fan Bua Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Biao Yanga Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Juanjiang Chena Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Xiaomin Linb Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaView further author information
,
Xiumei Hua Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China;b Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
View further author information
,
Lei Zhengb Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
View further author information
&
Qian Wanga Center for Clinical Laboratory, Zhujiang Hospital, Southern Medical University, Guangzhou, People’s Republic of China;b Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-0299-4462View further author information
ORCID Icon show all
Pages 1281-1292 | Received 27 Jan 2022, Accepted 10 Apr 2022, Published online: 23 May 2022

Citations (20)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Cong Zhou, Hui Zhang, Maosuo Xu, Yajuan Liu, Baoyu Yuan, Yong Lin & Fang Shen. (2024) Within-Host Resistance and Virulence Evolution of a Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae ST11 Under Antibiotic Pressure. Infection and Drug Resistance 16, pages 7255-7270.
Read now
Junjun Chen, Huan Zhang & Xuelian Liao. (2024) Hypervirulent Klebsiella pneumoniae. Infection and Drug Resistance 16, pages 5243-5249.
Read now
Zhen Shen, Juanxiu Qin, Guoxiu Xiang, Tianchi Chen, Nadira Nurxat, Qianqian Gao, Chen Wang, Haomin Zhang, Yao Liu & Min Li. (2024) Outer membrane vesicles mediating horizontal transfer of the epidemic blaOXA-232 carbapenemase gene among Enterobacterales. Emerging Microbes & Infections 13:1.
Read now
Velia Verónica Rangel-Ramírez, Hilda Minerva González-Sánchez & César Lucio-García. (2023) Exosomes: from biology to immunotherapy in infectious diseases. Infectious Diseases 55:2, pages 79-107.
Read now

Articles from other publishers (16)

Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Kyung-Jin Cho & Young-Mog Kim. (2024) Bacterial extracellular vesicles: Modulation of biofilm and virulence properties. Acta Biomaterialia 178, pages 13-23.
Crossref
Fangfang Fan, Guangzhang Chen, Siqian Deng & Li Wei. (2024) Proteomic analysis of meropenem-induced outer membrane vesicles released by carbapenem-resistant Klebsiella pneumoniae . Microbiology Spectrum 12:2.
Crossref
Ya-Sung Yang, Hung-Jui Chen, Xiao-Chun Chen, Hung-Jen Tang, Fang-Ju Chang, Yun-Ling Huang, Yu-Ling Pan, Dinesh Kumar Kesavan, Huan-Yuan Chen, Hung-Sheng Shang, Shu-Chen Kuo, Te-Li Chen & Ming-Hsien Chiang. (2023) Elizabethkingia anophelis outer membrane vesicles as a novel vaccine candidate against infection: insights into immune response and potential for passive immunity . mSphere 8:6.
Crossref
Danni Pu, Jiankang Zhao, Kang Chang, Xianxia Zhuo & Bin Cao. (2023) “Superbugs” with hypervirulence and carbapenem resistance in Klebsiella pneumoniae: the rise of such emerging nosocomial pathogens in China. Science Bulletin 68:21, pages 2658-2670.
Crossref
Mohammad Habibur Rahman, Salauddin Al Azad, Mohammad Fahim Uddin, Maisha Farzana, Iffat Ara Sharmeen, Kaifi Sultana Kabbo, Anika Jabin, Ashfaque Rahman, Farhan Jamil, Sanjida Ahmed Srishti, Fahmida Haque Riya, Towhid Khan, Rasel Ahmed, Nurunnahar, Samiur Rahman, Mohammad Ferdousur Rahman Khan & Md. Bahanur Rahman. (2023) WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing Klebsiella pneumoniae strain: a novel molecular target of selective flavonoids. Molecular Diversity.
Crossref
Beatrice Marinacci, Paweł Krzyżek, Benedetta Pellegrini, Gabriele Turacchio & Rossella Grande. (2023) Latest Update on Outer Membrane Vesicles and Their Role in Horizontal Gene Transfer: A Mini-Review. Membranes 13:11, pages 860.
Crossref
Gloria Luz Paniagua-Contreras, Areli Bautista-Cerón, Rosario Morales-Espinosa, Gabriela Delgado, Felipe Vaca-Paniagua, Clara Estela Díaz-Velásquez, Aldo Hugo de la Cruz-Montoya, Luis Rey García-Cortés, María Patricia Sánchez-Yáñez & Eric Monroy-Pérez. (2023) Extensive Expression of the Virulome Related to Antibiotic Genotyping in Nosocomial Strains of Klebsiella pneumoniae. International Journal of Molecular Sciences 24:19, pages 14754.
Crossref
Chenshuo Luo, Yanshu Chen, Xueni Hu, Shanjian Chen, Yulan Lin, Xiaoqian Liu & Bin Yang. (2023) Genetic and Functional Analysis of the pks Gene in Clinical Klebsiella pneumoniae Isolates . Microbiology Spectrum 11:4.
Crossref
Minghui Wen, Jingyu Wang, Zihao Ou, Guangjun Nie, Ye Chen, Min Li, Zhiwei Wu, Sidong Xiong, Hongwei Zhou, Zifeng Yang, Gang Long, Jiacan Su, Han Liu, Yingying Jing, Zhenke Wen, Yuxuan Fu, Tieli Zhou, Hui Xie, Wenda Guan, Xi Sun, Zhang Wang, Juan Wang, Xunxun Chen, Linglei Jiang, Xiaolin Qin, Yicong Xue, Mei Huang, Xinyue Huang, Ruoru Pan, Haojun Zhen, Yuqi Du, Qianbei Li, Xixin Huang, Yuanyuan Wu, Pingping Wang, Kening Zhao, Bo Situ, Xiumei Hu & Lei Zheng. (2023) Bacterial extracellular vesicles: A position paper by the microbial vesicles task force of the Chinese society for extracellular vesicles. Interdisciplinary Medicine 1:3.
Crossref
Aline Castro Rodrigues Lucena, Mariana Galvão Ferrarini, Willian Klassen de Oliveira, Bruna Hilzendeger Marcon, Luis Gustavo Morello, Lysangela Ronalte Alves & Helisson Faoro. (2023) Modulation of Klebsiella pneumoniae Outer Membrane Vesicle Protein Cargo under Antibiotic Treatment. Biomedicines 11:6, pages 1515.
Crossref
Bin Tang, Awen Yang, Peilin Liu, Zhiqian Wang, Zijuan Jian, Xia Chen, Qun Yan, Xianghui Liang & Wenen Liu. (2023) Outer Membrane Vesicles Transmitting bla NDM-1 Mediate the Emergence of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae . Antimicrobial Agents and Chemotherapy 67:5.
Crossref
Xiaotuan Zhang, Changrui Qian, Miran Tang, Weiliang Zeng, Jingchun Kong, Cheng Fu, Chunquan Xu, Jianzhong Ye & Tieli Zhou. (2023) Carbapenemase-loaded outer membrane vesicles protect Pseudomonas aeruginosa by degrading imipenem and promoting mutation of antimicrobial resistance gene. Drug Resistance Updates 68, pages 100952.
Crossref
V. M. Chernov, A. A. Mouzykantov, N. B. Baranova & O. A. Chernova. (2023) Extracellular Vesicles of Bacteria Mediate Intercellular Communication: Practical Applications and Biosafety. Applied Biochemistry and Microbiology 59:2, pages 99-110.
Crossref
V. M. Chernov, A. A. Mouzykantov, N. B. Baranova & O. A. Chernova. (2023) Extracellular Vesicles of Bacteria Mediate Intercellular Communication: Practical Applications and Biosafety (Review). Прикладная биохимия и микробиология 59:2, pages 107-119.
Crossref
Jeong Yeon Kim, Jin Woong Suh, Jae Seong Kang, Sun Bean Kim, Young Kyung Yoon & Jang Wook Sohn. (2023) Gram-Negative Bacteria’s Outer Membrane Vesicles. Infection & Chemotherapy 55:1, pages 1.
Crossref
Ping Li, Wanying Luo, Tian-Xin Xiang, Yuhuan Jiang, Peng Liu, Dan-Dan Wei, Linping Fan, Shanshan Huang, Wenjian Liao, Yang Liu & Wei Zhang. (2022) Horizontal gene transfer via OMVs co-carrying virulence and antimicrobial-resistant genes is a novel way for the dissemination of carbapenem-resistant hypervirulent Klebsiella pneumoniae. Frontiers in Microbiology 13.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.